JP2007530598A - マクロファージ遊走阻害因子の阻害に関する、化合物、組成物、作製プロセス、および使用方法 - Google Patents
マクロファージ遊走阻害因子の阻害に関する、化合物、組成物、作製プロセス、および使用方法 Download PDFInfo
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- JP2007530598A JP2007530598A JP2007505270A JP2007505270A JP2007530598A JP 2007530598 A JP2007530598 A JP 2007530598A JP 2007505270 A JP2007505270 A JP 2007505270A JP 2007505270 A JP2007505270 A JP 2007505270A JP 2007530598 A JP2007530598 A JP 2007530598A
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US55644004P | 2004-03-26 | 2004-03-26 | |
| PCT/US2005/010444 WO2005094329A2 (en) | 2004-03-26 | 2005-03-28 | Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor |
Publications (2)
| Publication Number | Publication Date |
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| JP2007530598A true JP2007530598A (ja) | 2007-11-01 |
| JP2007530598A5 JP2007530598A5 (https=) | 2008-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2007505270A Pending JP2007530598A (ja) | 2004-03-26 | 2005-03-28 | マクロファージ遊走阻害因子の阻害に関する、化合物、組成物、作製プロセス、および使用方法 |
Country Status (9)
| Country | Link |
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| US (3) | US20050250826A1 (https=) |
| EP (1) | EP1727542A4 (https=) |
| JP (1) | JP2007530598A (https=) |
| CN (1) | CN101098697B (https=) |
| AU (1) | AU2005228417A1 (https=) |
| BR (1) | BRPI0507818A (https=) |
| CA (1) | CA2557166C (https=) |
| MX (1) | MXPA06010793A (https=) |
| WO (1) | WO2005094329A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013161933A1 (ja) * | 2012-04-26 | 2013-10-31 | 富山化学工業株式会社 | 重水素化含窒素複素環カルボキサミド誘導体 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005219788B2 (en) | 2004-03-05 | 2010-06-03 | Nissan Chemical Corporation | Isoxazoline-substituted benzamide compound and noxious organism control agent |
| TW200803740A (en) | 2005-12-16 | 2008-01-16 | Du Pont | 5-aryl isoxazolines for controlling invertebrate pests |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| EP2004192B1 (en) * | 2006-03-24 | 2014-03-12 | The Feinstein Institute for Medical Research | Modified macrophage migration inhibitory factor inhibitors |
| AU2008261793A1 (en) | 2007-06-13 | 2008-12-18 | E. I. Du Pont De Nemours And Company | Isoxazoline insecticides |
| TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
| ES2549731T3 (es) | 2007-06-27 | 2015-11-02 | E. I. Du Pont De Nemours And Company | Método para el control de plagas en animales |
| TWI649303B (zh) | 2007-08-17 | 2019-02-01 | 杜邦股份有限公司 | 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法 |
| US8367584B2 (en) | 2007-10-03 | 2013-02-05 | E.I. Du Pont De Nemours And Company | Naphthalene isoxazoline compounds for control of invertebrate pests |
| TWI518076B (zh) | 2008-04-09 | 2016-01-21 | 杜邦股份有限公司 | 製備雜環化合物之方法 |
| US8691824B2 (en) | 2008-08-04 | 2014-04-08 | Chdi Foundation, Inc. | Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
| US8765735B2 (en) | 2009-05-18 | 2014-07-01 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US9149465B2 (en) | 2009-05-18 | 2015-10-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US8927551B2 (en) | 2009-05-18 | 2015-01-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| WO2011066482A2 (en) * | 2009-11-25 | 2011-06-03 | Cytokine Pharmasciences, Inc. | Chiral synthesis of isoxazolines, isoxazoline compounds, and uses thereof |
| WO2011091040A1 (en) * | 2010-01-19 | 2011-07-28 | Cytokine Pharmasciences, Inc. | Use of isoxazoline compounds and compositions in bladder cancer |
| RS54677B1 (sr) | 2010-05-27 | 2016-08-31 | E. I. Du Pont De Nemours And Company | Kristalni oblici 4-[5-[3-hloro-5-(trifluorometil)fenil]-4,5 -dihidro-5-(trifluorometil)-3-izoksazolil]-n-[2-okso-2-[(2,2,2-trifluoroetil)amino]etil]-1-naftalenkarboksamida |
| WO2013010955A1 (en) | 2011-07-15 | 2013-01-24 | Morphosys Ag | Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt) |
| SI2750677T1 (sl) | 2011-08-30 | 2017-10-30 | Chdi Foundation, Inc. | Inhibitorji kinurenin-3-monooksigenaze, farmacevtski sestavki in postopki njihove uporabe |
| KR20140072037A (ko) | 2011-08-30 | 2014-06-12 | 씨에이치디아이 파운데이션, 인코포레이티드 | 키뉴레닌-3-모노옥시게나제 억제제, 약학적 조성물 및 이의 사용 방법 |
| WO2013184884A1 (en) | 2012-06-06 | 2013-12-12 | Basf Corporation | Improved methods for botanical and/or algae extraction |
| EP2944310B1 (en) | 2014-05-16 | 2018-03-21 | Mifcare | MIF inhibitors for the acute or chronic treatment of pulmonary hypertension |
| AU2015289492B2 (en) | 2014-07-17 | 2020-02-20 | Chdi Foundation, Inc. | Methods and compositions for treating HIV-related disorders |
| US11397182B2 (en) | 2014-10-07 | 2022-07-26 | Cornell University | Methods for prognosing and preventing metastatic liver disease |
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| JPH03220180A (ja) * | 1990-01-24 | 1991-09-27 | Taiho Yakuhin Kogyo Kk | イソキサゾリン誘導体 |
| JPH0741459A (ja) * | 1993-07-29 | 1995-02-10 | Sumitomo Pharmaceut Co Ltd | 新規エラスターゼ阻害剤 |
| JP2002507965A (ja) * | 1997-06-20 | 2002-03-12 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス） | 新規な２−（イミノメチル）アミノフェニル誘導体、その製造、医薬としての用途及びこれを含有する医薬組成物 |
| WO2002100332A2 (en) * | 2001-06-08 | 2002-12-19 | Cytokine Pharmasciences, Inc. | Isoxazoline compounds having mif antagonist activity |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4933464A (en) * | 1988-04-25 | 1990-06-12 | W. R. Grace & Co.-Conn. | Process for forming 3-phenylisoxazolines and 3-phenylisoxazoles |
| JP2738486B2 (ja) * | 1992-11-20 | 1998-04-08 | ファイザー製薬株式会社 | 抗炎症剤としての新規なイソオキサゾリン類 |
| US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
| CN1046274C (zh) * | 1993-11-26 | 1999-11-10 | 辉瑞大药厂 | 用作消炎剂的异噁唑啉化合物 |
| JP2818820B2 (ja) * | 1993-11-26 | 1998-10-30 | ファイザー・インク． | 抗炎症剤としての３−アリール−２−イソオキサゾリン類 |
| DE69503769T2 (de) * | 1994-03-09 | 1998-12-03 | Pfizer Inc., New York, N.Y. | Isoxazoline verbindung zur hemmung tnf-freigabe |
| US6492428B1 (en) * | 2000-07-26 | 2002-12-10 | The Picower Institute For Medical Research | Compounds having MIF antagonist activity |
| US6420188B1 (en) * | 1996-02-16 | 2002-07-16 | The Picower Institute For Medical Research | Screening assay for the identification of inhibitors for macrophage migration inhibitory factor |
| US6335445B1 (en) * | 1997-03-24 | 2002-01-01 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them |
| CA2389229A1 (en) * | 1999-10-29 | 2001-05-10 | The Picower Institute For Medical Research | Compounds having mif antagonist activity |
| US20050202010A1 (en) * | 2003-08-29 | 2005-09-15 | Giroir Brett P. | Method of treatment and bioassay involving macrophage migration inhibitory factor (MIF) as cardiac-derived myocardial depressant factor |
| WO2005058845A2 (en) * | 2003-12-19 | 2005-06-30 | Novo Nordisk A/S | Novel glucagon antagonists/inverse agonists |
-
2005
- 2005-03-28 US US11/090,128 patent/US20050250826A1/en not_active Abandoned
- 2005-03-28 EP EP05742932A patent/EP1727542A4/en not_active Withdrawn
- 2005-03-28 BR BRPI0507818-0A patent/BRPI0507818A/pt not_active IP Right Cessation
- 2005-03-28 CN CN2005800098795A patent/CN101098697B/zh not_active Expired - Fee Related
- 2005-03-28 WO PCT/US2005/010444 patent/WO2005094329A2/en not_active Ceased
- 2005-03-28 JP JP2007505270A patent/JP2007530598A/ja active Pending
- 2005-03-28 MX MXPA06010793A patent/MXPA06010793A/es active IP Right Grant
- 2005-03-28 CA CA2557166A patent/CA2557166C/en not_active Expired - Fee Related
- 2005-03-28 AU AU2005228417A patent/AU2005228417A1/en not_active Abandoned
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2007
- 2007-05-01 US US11/742,978 patent/US20080113997A1/en not_active Abandoned
-
2012
- 2012-09-25 US US13/626,816 patent/US20130225586A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03220180A (ja) * | 1990-01-24 | 1991-09-27 | Taiho Yakuhin Kogyo Kk | イソキサゾリン誘導体 |
| JPH0741459A (ja) * | 1993-07-29 | 1995-02-10 | Sumitomo Pharmaceut Co Ltd | 新規エラスターゼ阻害剤 |
| JP2002507965A (ja) * | 1997-06-20 | 2002-03-12 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス） | 新規な２−（イミノメチル）アミノフェニル誘導体、その製造、医薬としての用途及びこれを含有する医薬組成物 |
| WO2002100332A2 (en) * | 2001-06-08 | 2002-12-19 | Cytokine Pharmasciences, Inc. | Isoxazoline compounds having mif antagonist activity |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013161933A1 (ja) * | 2012-04-26 | 2013-10-31 | 富山化学工業株式会社 | 重水素化含窒素複素環カルボキサミド誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005228417A1 (en) | 2005-10-13 |
| US20080113997A1 (en) | 2008-05-15 |
| US20050250826A1 (en) | 2005-11-10 |
| WO2005094329A8 (en) | 2006-01-05 |
| CA2557166A1 (en) | 2005-10-13 |
| CN101098697A (zh) | 2008-01-02 |
| WO2005094329A3 (en) | 2007-02-08 |
| US20130225586A1 (en) | 2013-08-29 |
| EP1727542A4 (en) | 2009-08-05 |
| EP1727542A2 (en) | 2006-12-06 |
| CN101098697B (zh) | 2010-11-10 |
| CA2557166C (en) | 2015-06-30 |
| MXPA06010793A (es) | 2006-12-19 |
| BRPI0507818A (pt) | 2007-07-10 |
| WO2005094329A2 (en) | 2005-10-13 |
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