JP2007528876A5 - - Google Patents
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- Publication number
- JP2007528876A5 JP2007528876A5 JP2006554335A JP2006554335A JP2007528876A5 JP 2007528876 A5 JP2007528876 A5 JP 2007528876A5 JP 2006554335 A JP2006554335 A JP 2006554335A JP 2006554335 A JP2006554335 A JP 2006554335A JP 2007528876 A5 JP2007528876 A5 JP 2007528876A5
- Authority
- JP
- Japan
- Prior art keywords
- film
- caffeine
- active ingredient
- mixture
- starch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical group CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims 14
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims 7
- 229960001948 caffeine Drugs 0.000 claims 7
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims 7
- 239000004480 active ingredient Substances 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 229920002472 Starch Polymers 0.000 claims 4
- 235000019698 starch Nutrition 0.000 claims 4
- 239000008107 starch Substances 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 229920000881 Modified starch Polymers 0.000 claims 1
- 239000004368 Modified starch Substances 0.000 claims 1
- 238000013019 agitation Methods 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 235000019426 modified starch Nutrition 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
Claims (13)
- 活性成分とフィルム形成性成分とを含む混合物を形成し、該混合物を基材材料上にコーティングすることによりフィルムを形成し、次いで湿分約１５重量％未満の含水率まで該フィルムを乾燥させることによって調製された、活性成分を含有する可溶性のフィルムであって、前記活性成分が、室温において約１ｇ／４ｍＬ未満の水溶性を有し、そして該活性成分を含有する可溶性フィルムの単回投与形態の投与に所望の作用を与えるのに十分な量でフィルム中に存在するものである、フィルム。
- 前記活性成分の室温における水溶性が約１ｇ／１０ｍＬ未満である、請求項１に記載のフィルム。
- 前記混合物が溶液の形態を成す、請求項１に記載のフィルム。
- 前記混合物に熱及び／又は撹拌を加えると、溶液が形成される、請求項３に記載のフィルム。
- 前記混合物が懸濁液の形態を成す、請求項１に記載のフィルム。
- 前記活性成分がカフェインである、請求項３に記載のフィルム。
- 最終調製されたフィルムの重量を基準として約１８乾燥重量％以上のカフェインを含む、請求項６に記載のフィルム。
- 約２０乾燥重量％以上のカフェインを含む、請求項７に記載のフィルム。
- 約２５乾燥重量％以上のカフェインを含む、請求項８に記載のフィルム。
- 前記フィルム形成性成分が、約８５％以上の化工澱粉を含む澱粉成分を含むものである、請求項１に記載のフィルム。
- 前記澱粉は、ヒドロキシアルキル化澱粉及びスクシネート化澱粉から成る群から選択されるものである、請求項１０に記載のフィルム。
- フィルムの重量を基準として、約１８乾燥重量％以上のカフェインを含む、可溶性のカフェイン含有フィルム。
- 単回投与フィルム当たり約２０ｍｇ〜約３０ｍｇのカフェインを含む、単回投与用の請求項１２に記載の可溶性のカフェイン含有フィルム。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/783,080 US20050186257A1 (en) | 2004-02-20 | 2004-02-20 | Dissolvable film and method of manufacture |
| PCT/US2005/006106 WO2005082048A2 (en) | 2004-02-20 | 2005-02-18 | Dissolvable film and method of manufacture |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012262781A Division JP2013056935A (ja) | 2004-02-20 | 2012-11-30 | 可溶性フィルム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007528876A JP2007528876A (ja) | 2007-10-18 |
| JP2007528876A5 true JP2007528876A5 (ja) | 2008-04-03 |
Family
ID=34861142
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006554335A Withdrawn JP2007528876A (ja) | 2004-02-20 | 2005-02-18 | 可溶性フィルム及び製造方法 |
| JP2012262781A Pending JP2013056935A (ja) | 2004-02-20 | 2012-11-30 | 可溶性フィルム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012262781A Pending JP2013056935A (ja) | 2004-02-20 | 2012-11-30 | 可溶性フィルム |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20050186257A1 (ja) |
| EP (1) | EP1715846A2 (ja) |
| JP (2) | JP2007528876A (ja) |
| CN (2) | CN1921832A (ja) |
| WO (1) | WO2005082048A2 (ja) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8627828B2 (en) | 2003-11-07 | 2014-01-14 | U.S. Smokeless Tobacco Company Llc | Tobacco compositions |
| BRPI0415741B1 (pt) | 2003-11-07 | 2013-07-23 | composições de tabaco e métodos de fabricação de uma composição de tabaco | |
| US20060228319A1 (en) * | 2005-04-11 | 2006-10-12 | Vona Samuel A Jr | Personal cleansing and shaving films |
| US20070190013A1 (en) * | 2006-02-13 | 2007-08-16 | Yeli Zhang | Film and film-forming compositions |
| US20070258941A1 (en) * | 2006-05-02 | 2007-11-08 | Pfister Brian E | Methods and compositions for remediation of disc herniation by modifying structure |
| US20070292482A1 (en) * | 2006-06-14 | 2007-12-20 | Conopco, Inc., D/B/A Unilever | Delivery System |
| US20070292480A1 (en) * | 2006-06-14 | 2007-12-20 | Conopco, Inc., D/B/A Unilever | Delivery System for Ingestible Components |
| US20080220029A1 (en) * | 2007-03-05 | 2008-09-11 | Charlene Ng | Fast-dissolving/disintegrating film preparation having high proportion of active |
| CA2691236A1 (en) * | 2007-06-29 | 2009-01-08 | Union Carbide Chemicals & Plastics Technology Llc | Personal care dissolvable films |
| JP2010532374A (ja) * | 2007-06-29 | 2010-10-07 | ユニオン カーバイド ケミカルズ アンド プラスティックス テクノロジー エルエルシー | ヘアスタイリングおよびコンディショニングパーソナルケアフィルム |
| BRPI0811707A2 (pt) * | 2007-06-29 | 2014-09-30 | Union Carbide Chem Plastic | Película dissolvível para cuidados pessoais |
| WO2009005814A2 (en) * | 2007-07-03 | 2009-01-08 | Marchitto Kevin S | Drug-delivery patch comprising a dissolvable layer and uses thereof |
| US20090298946A1 (en) * | 2008-06-02 | 2009-12-03 | Cleavelin Cody R | Local Anesthetic Deactivation |
| WO2010086989A1 (ja) | 2009-01-29 | 2010-08-05 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
| US20110136815A1 (en) * | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| CN102821754B (zh) | 2010-03-26 | 2014-06-18 | 陶氏环球技术有限责任公司 | 多层熔融挤出膜 |
| JP5751868B2 (ja) | 2010-03-30 | 2015-07-22 | 日東電工株式会社 | フィルム状製剤及びその製造方法 |
| JP2011207847A (ja) | 2010-03-30 | 2011-10-20 | Nitto Denko Corp | フィルム状製剤及びその製造方法 |
| CN103403108B (zh) | 2010-12-13 | 2016-08-10 | 奥驰亚客户服务有限责任公司 | 制备印刷溶液和制造图案化的香烟包装物的方法 |
| US11707082B2 (en) | 2010-12-13 | 2023-07-25 | Altria Client Services Llc | Process of preparing printing solution and making patterned cigarette wrapper |
| JP5841433B2 (ja) | 2012-01-11 | 2016-01-13 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
| WO2014070485A1 (en) * | 2012-10-22 | 2014-05-08 | 2010 Mfi, Llc | Dissolvable strip for treatment of oral thermal burns |
| US11446364B2 (en) | 2012-11-14 | 2022-09-20 | Smith & Nephew, Inc. | Stable thermolysin hydrogel |
| US11452698B2 (en) | 2013-03-15 | 2022-09-27 | Smith & Nephew, Inc. | Dissolvable gel-forming film for delivery of active agents |
| JP6574556B2 (ja) | 2014-08-27 | 2019-09-11 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
| US20160220480A1 (en) * | 2015-02-03 | 2016-08-04 | Intelgenx Corp. | Oral dosage film exhibiting enhanced mucosal penetration |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03112450A (ja) * | 1989-09-24 | 1991-05-14 | Masahiko Maeda | 眠気防止用チューインガム |
| JP2863586B2 (ja) * | 1990-02-27 | 1999-03-03 | 株式会社ロッテ | 眼気防止チューインガム |
| AU2703795A (en) * | 1994-06-23 | 1996-01-19 | Procter & Gamble Company, The | Treatment of nicotine craving and/or smoking withdrawal symptoms with a transdermal or transmucosal composition containing nicotine and caffeine or xanthine |
| US6596298B2 (en) * | 1998-09-25 | 2003-07-22 | Warner-Lambert Company | Fast dissolving orally comsumable films |
| DE19954421A1 (de) * | 1999-11-12 | 2001-05-31 | Lohmann Therapie Syst Lts | Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen |
| WO2002074238A2 (en) * | 2001-02-16 | 2002-09-26 | Lavipharm Laboratories Inc. | Water soluble and palatable complexes |
| WO2003030883A1 (en) * | 2001-10-12 | 2003-04-17 | Kosmos Pharma | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| JP2003213038A (ja) * | 2001-11-16 | 2003-07-30 | Natl Starch & Chem Investment Holding Corp | デンプンを含有するフィルム |
| DE10207394B4 (de) * | 2002-02-21 | 2007-03-29 | Lts Lohmann Therapie-Systeme Ag | Geschmacksmaskierte oblatenförmige Arzneizubereitung |
| US20050013847A1 (en) * | 2003-04-14 | 2005-01-20 | Fmc Corporation | Delivery systems of homogeneous, thermoreversible alginate films |
-
2004
- 2004-02-20 US US10/783,080 patent/US20050186257A1/en not_active Abandoned
-
2005
- 2005-02-18 WO PCT/US2005/006106 patent/WO2005082048A2/en not_active Application Discontinuation
- 2005-02-18 CN CNA2005800051712A patent/CN1921832A/zh active Pending
- 2005-02-18 EP EP05723811A patent/EP1715846A2/en not_active Withdrawn
- 2005-02-18 JP JP2006554335A patent/JP2007528876A/ja not_active Withdrawn
- 2005-02-18 CN CN2012100625634A patent/CN102600111A/zh active Pending
-
2012
- 2012-11-30 JP JP2012262781A patent/JP2013056935A/ja active Pending
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