JP2007528409A - プロテアーゼインヒビターの低用量吸入による慢性閉塞性肺疾患の処置 - Google Patents
プロテアーゼインヒビターの低用量吸入による慢性閉塞性肺疾患の処置 Download PDFInfo
- Publication number
- JP2007528409A JP2007528409A JP2007503004A JP2007503004A JP2007528409A JP 2007528409 A JP2007528409 A JP 2007528409A JP 2007503004 A JP2007503004 A JP 2007503004A JP 2007503004 A JP2007503004 A JP 2007503004A JP 2007528409 A JP2007528409 A JP 2007528409A
- Authority
- JP
- Japan
- Prior art keywords
- aat
- functionally active
- less
- active portion
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES OF CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D1/00—Cigars; Cigarettes
- A24D1/002—Cigars; Cigarettes with additives, e.g. for flavouring
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES OF CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter tips or filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces of cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/14—Use of materials for tobacco smoke filters of organic materials as additive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials Engineering (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55185604P | 2004-03-09 | 2004-03-09 | |
| PCT/US2005/007959 WO2005086915A2 (en) | 2004-03-09 | 2005-03-09 | Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007528409A true JP2007528409A (ja) | 2007-10-11 |
| JP2007528409A5 JP2007528409A5 (https=) | 2009-08-06 |
Family
ID=34976236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007503004A Pending JP2007528409A (ja) | 2004-03-09 | 2005-03-09 | プロテアーゼインヒビターの低用量吸入による慢性閉塞性肺疾患の処置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7914771B2 (https=) |
| EP (1) | EP1737499A4 (https=) |
| JP (1) | JP2007528409A (https=) |
| AU (1) | AU2005221151A1 (https=) |
| CA (1) | CA2559062A1 (https=) |
| WO (1) | WO2005086915A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016528234A (ja) * | 2013-08-05 | 2016-09-15 | フォールマン、ジェラルド | 喫煙の悪影響を減らす新規手段 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060257324A1 (en) | 2000-05-22 | 2006-11-16 | Chiesi Farmaceutici S.P.A. | Pharmaceutical solution formulations for pressurised metered dose inhalers |
| EP1737499A4 (en) * | 2004-03-09 | 2009-07-22 | Arriva Pharmaceuticals Inc | TREATMENT OF CHRONIC OBSTRUCTIVE LUNG DISEASE BY INHALATION OF LOW DOSES OF A PROTEASE HEMMER |
| EP1981572B1 (en) | 2006-02-09 | 2012-11-21 | Kamada Ltd. | Pulmonary delivery of alpha-i proteinase inhibitor |
| WO2008053199A1 (en) * | 2006-10-30 | 2008-05-08 | Astrazeneca Ab | Combination therapy for the treatment of respiratory diseases |
| GB0716026D0 (en) * | 2007-08-16 | 2007-09-26 | Norton Healthcare Ltd | An inhalable medicament |
| AU2012275295B2 (en) * | 2011-06-28 | 2016-11-10 | Inhibrx, Lp | WAP domain fusion polypeptides and methods of use thereof |
| US10400029B2 (en) | 2011-06-28 | 2019-09-03 | Inhibrx, Lp | Serpin fusion polypeptides and methods of use thereof |
| KR102231139B1 (ko) * | 2011-06-28 | 2021-03-24 | 인히브릭스, 인크. | 세르핀 융합 폴리펩타이드 및 이의 이용 방법 |
| GB201200525D0 (en) | 2011-12-19 | 2012-02-29 | Teva Branded Pharmaceutical Prod R & D Inc | An inhalable medicament |
| KR20140108516A (ko) | 2011-12-30 | 2014-09-11 | 그리폴스, 에스.에이. | 폐 악화의 발현 또는 진행을 지연시키기 위한 알파1-프로테이나제 억제제 |
| WO2014089262A1 (en) * | 2012-12-07 | 2014-06-12 | Virginia Commonwealth University | Diagnosis and therapy of chronic inflammation-induced disorders |
| US10034866B2 (en) | 2014-06-19 | 2018-07-31 | Teva Branded Pharmaceutical Products R&D, Inc. | Inhalable medicament comprising tiotropium |
| WO2018116300A1 (en) * | 2016-12-22 | 2018-06-28 | Kamada Ltd. | Dry powder formulations of alpha-1 antitrypsin |
| EP3915574A1 (en) * | 2020-05-27 | 2021-12-01 | Grifols Worldwide Operations Limited | Method for the treatment of cytokine release syndrome |
| US12440488B2 (en) | 2020-12-01 | 2025-10-14 | Reverspah Llc | Methods and compositions for treating chronic obstructive pulmonary disease, asthma, pneumonia, bronchitis, cystic fibrosis, pulmonary edema, interstitial lung disease, sarcoidosis, idiopathic pulmonary fibrosis, acute respiratory distress syndrome, and pulmonary arterial hypertension |
| US11324694B1 (en) * | 2021-10-28 | 2022-05-10 | Cmpd Licensing, Llc | Nebulization formulations for delivery to lower respiratory tract |
| WO2023091081A2 (en) * | 2021-11-16 | 2023-05-25 | Agency For Science, Technology And Research | Inhalable recombinant protein powder formulation for treating genetic and autoimmune disorders |
| EP4480493A1 (en) | 2023-06-22 | 2024-12-25 | AATEC Medical GmbH | A recombinant human alpha-1 antitrypsin glycoprotein for treating non-viral inflammatory diseases of the lung |
Citations (4)
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| JPH1045799A (ja) * | 1982-08-13 | 1998-02-17 | Zymogenetics Inc | 形質転換酵母を用いて製造した蛋白質 |
| WO2003035610A1 (en) * | 2001-10-26 | 2003-05-01 | Shionogi & Co., Ltd. | Sulfonamide derivative having mmp inhibitory activity |
| JP2003523393A (ja) * | 2000-02-25 | 2003-08-05 | アラキス リミテッド | 呼吸器疾患治療用メタロプロティナーゼ阻害剤 |
| WO2003091242A1 (en) * | 2002-04-26 | 2003-11-06 | Takeda Pharmaceutical Company Limited | Novel thiol derivative, process for producing the same and use thereof |
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| US4083372A (en) | 1976-05-24 | 1978-04-11 | Robert Boden | Cigarette-simulating inhaler |
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| US4870008A (en) | 1983-08-12 | 1989-09-26 | Chiron Corporation | Secretory expression in eukaryotes |
| US4752576A (en) | 1984-06-14 | 1988-06-21 | Chiron Corporation | Expression of α-1 antitrypsin in yeast |
| US4732973A (en) | 1984-06-14 | 1988-03-22 | Chiron Corporation | Active site modified protease α-1-antitrypsin inhibitors |
| US4837148A (en) | 1984-10-30 | 1989-06-06 | Phillips Petroleum Company | Autonomous replication sequences for yeast strains of the genus pichia |
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-
2005
- 2005-03-09 EP EP05725249A patent/EP1737499A4/en not_active Withdrawn
- 2005-03-09 JP JP2007503004A patent/JP2007528409A/ja active Pending
- 2005-03-09 CA CA002559062A patent/CA2559062A1/en not_active Abandoned
- 2005-03-09 WO PCT/US2005/007959 patent/WO2005086915A2/en not_active Ceased
- 2005-03-09 US US11/077,276 patent/US7914771B2/en not_active Expired - Fee Related
- 2005-03-09 AU AU2005221151A patent/AU2005221151A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1045799A (ja) * | 1982-08-13 | 1998-02-17 | Zymogenetics Inc | 形質転換酵母を用いて製造した蛋白質 |
| JP2003523393A (ja) * | 2000-02-25 | 2003-08-05 | アラキス リミテッド | 呼吸器疾患治療用メタロプロティナーゼ阻害剤 |
| WO2003035610A1 (en) * | 2001-10-26 | 2003-05-01 | Shionogi & Co., Ltd. | Sulfonamide derivative having mmp inhibitory activity |
| WO2003091242A1 (en) * | 2002-04-26 | 2003-11-06 | Takeda Pharmaceutical Company Limited | Novel thiol derivative, process for producing the same and use thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016528234A (ja) * | 2013-08-05 | 2016-09-15 | フォールマン、ジェラルド | 喫煙の悪影響を減らす新規手段 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1737499A4 (en) | 2009-07-22 |
| WO2005086915A2 (en) | 2005-09-22 |
| US7914771B2 (en) | 2011-03-29 |
| EP1737499A2 (en) | 2007-01-03 |
| CA2559062A1 (en) | 2005-09-22 |
| WO2005086915A3 (en) | 2006-03-23 |
| AU2005221151A1 (en) | 2005-09-22 |
| US20050201951A1 (en) | 2005-09-15 |
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Legal Events
| Date | Code | Title | Description |
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Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20080307 |
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| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090622 |
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