JP2007522195A5 - - Google Patents
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- JP2007522195A5 JP2007522195A5 JP2006552692A JP2006552692A JP2007522195A5 JP 2007522195 A5 JP2007522195 A5 JP 2007522195A5 JP 2006552692 A JP2006552692 A JP 2006552692A JP 2006552692 A JP2006552692 A JP 2006552692A JP 2007522195 A5 JP2007522195 A5 JP 2007522195A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- cells
- cell
- support matrix
- matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 35
- 210000004027 cell Anatomy 0.000 claims 29
- 239000011159 matrix material Substances 0.000 claims 18
- 206010052428 Wound Diseases 0.000 claims 12
- 208000027418 Wounds and injury Diseases 0.000 claims 12
- 210000002950 fibroblast Anatomy 0.000 claims 10
- 102000009123 Fibrin Human genes 0.000 claims 9
- 108010073385 Fibrin Proteins 0.000 claims 9
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 9
- 229950003499 fibrin Drugs 0.000 claims 9
- 238000011534 incubation Methods 0.000 claims 6
- 210000003491 skin Anatomy 0.000 claims 6
- 239000000463 material Substances 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- 230000002500 effect on skin Effects 0.000 claims 3
- 230000000699 topical effect Effects 0.000 claims 3
- 108010049003 Fibrinogen Proteins 0.000 claims 2
- 102000008946 Fibrinogen Human genes 0.000 claims 2
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 claims 2
- 108090000190 Thrombin Proteins 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940012952 fibrinogen Drugs 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 2
- 238000006116 polymerization reaction Methods 0.000 claims 2
- 230000001698 pyrogenic effect Effects 0.000 claims 2
- 239000002356 single layer Substances 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 229960004072 thrombin Drugs 0.000 claims 2
- 108010039627 Aprotinin Proteins 0.000 claims 1
- 206010056340 Diabetic ulcer Diseases 0.000 claims 1
- 208000028990 Skin injury Diseases 0.000 claims 1
- 208000000558 Varicose Ulcer Diseases 0.000 claims 1
- 238000005299 abrasion Methods 0.000 claims 1
- 229960004405 aprotinin Drugs 0.000 claims 1
- 230000018109 developmental process Effects 0.000 claims 1
- 230000000642 iatrogenic effect Effects 0.000 claims 1
- ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical group C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 claims 1
- 210000002510 keratinocyte Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 230000009758 senescence Effects 0.000 claims 1
- 230000037380 skin damage Effects 0.000 claims 1
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 claims 1
- 229960000401 tranexamic acid Drugs 0.000 claims 1
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0403226A GB0403226D0 (en) | 2004-02-13 | 2004-02-13 | Means of packaging a wound healing composition |
| GB0403220A GB0403220D0 (en) | 2004-02-13 | 2004-02-13 | Wound healing composition |
| GB0403226.4 | 2004-02-13 | ||
| GB0403220.7 | 2004-02-13 | ||
| US55619404P | 2004-03-25 | 2004-03-25 | |
| US55615504P | 2004-03-25 | 2004-03-25 | |
| US60/556,194 | 2004-03-25 | ||
| US60/556,155 | 2004-03-25 | ||
| GB0426252A GB0426252D0 (en) | 2004-11-30 | 2004-11-30 | Wound healing composition |
| GB0426252.3 | 2004-11-30 | ||
| US63242504P | 2004-12-01 | 2004-12-01 | |
| US60/632,425 | 2004-12-01 | ||
| PCT/GB2005/000523 WO2005079822A2 (en) | 2004-02-13 | 2005-02-14 | Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012135016A Division JP6141603B2 (ja) | 2004-02-13 | 2012-06-14 | 創傷治療組成物 |
| JP2014258639A Division JP6141821B2 (ja) | 2004-02-13 | 2014-12-22 | 創傷治癒組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007522195A JP2007522195A (ja) | 2007-08-09 |
| JP2007522195A5 true JP2007522195A5 (https=) | 2008-04-10 |
| JP5706058B2 JP5706058B2 (ja) | 2015-04-22 |
Family
ID=34891423
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006552692A Expired - Fee Related JP5706058B2 (ja) | 2004-02-13 | 2005-02-14 | 創傷治療組成物 |
| JP2012135016A Expired - Fee Related JP6141603B2 (ja) | 2004-02-13 | 2012-06-14 | 創傷治療組成物 |
| JP2014258639A Expired - Fee Related JP6141821B2 (ja) | 2004-02-13 | 2014-12-22 | 創傷治癒組成物 |
| JP2015075997A Pending JP2015134815A (ja) | 2004-02-13 | 2015-04-02 | 創傷治療組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012135016A Expired - Fee Related JP6141603B2 (ja) | 2004-02-13 | 2012-06-14 | 創傷治療組成物 |
| JP2014258639A Expired - Fee Related JP6141821B2 (ja) | 2004-02-13 | 2014-12-22 | 創傷治癒組成物 |
| JP2015075997A Pending JP2015134815A (ja) | 2004-02-13 | 2015-04-02 | 創傷治療組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8765169B2 (https=) |
| EP (2) | EP1718317A1 (https=) |
| JP (4) | JP5706058B2 (https=) |
| AU (2) | AU2005215213C1 (https=) |
| CA (2) | CA2556098C (https=) |
| WO (2) | WO2005079822A2 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0224986D0 (en) | 2002-10-28 | 2002-12-04 | Smith & Nephew | Apparatus |
| US8779053B2 (en) | 2003-08-25 | 2014-07-15 | Dow Global Technologies Llc | Coating compositions |
| US9169406B2 (en) | 2003-08-25 | 2015-10-27 | Dow Global Technologies Llc | Coating compositions |
| US8946329B2 (en) | 2003-08-25 | 2015-02-03 | Dow Global Technologies Llc | Coating compositions |
| US8722787B2 (en) | 2003-08-25 | 2014-05-13 | Dow Global Technologies Llc | Coating composition and articles made therefrom |
| US11298453B2 (en) | 2003-10-28 | 2022-04-12 | Smith & Nephew Plc | Apparatus and method for wound cleansing with actives |
| US8765169B2 (en) | 2004-02-13 | 2014-07-01 | Smith & Nephew, Inc. | Wound healing profile |
| GB0508531D0 (en) | 2005-04-27 | 2005-06-01 | Smith & Nephew | Sai with ultrasound |
| US7753894B2 (en) | 2004-04-27 | 2010-07-13 | Smith & Nephew Plc | Wound cleansing apparatus with stress |
| GB0409446D0 (en) | 2004-04-28 | 2004-06-02 | Smith & Nephew | Apparatus |
| CN100402097C (zh) * | 2006-07-24 | 2008-07-16 | 暨南大学 | 琼脂/胶原皮肤创伤修复敷料及其制备方法和应用 |
| FR2917629B1 (fr) * | 2007-06-22 | 2009-09-11 | Oreal | Utilisation cosmetique de proteines de type apolipoproteine d |
| WO2009045543A1 (en) * | 2007-10-04 | 2009-04-09 | The Regents Of The University Of California | Treatment of conditions related to shock |
| GB2457870A (en) | 2007-12-21 | 2009-09-02 | Intercytex Ltd | Wound Dressing Applicator |
| PT2352472T (pt) * | 2008-11-04 | 2017-04-11 | Stratatech Corp | Equivalentes de pele secos e irradiados prontos a utilizar |
| ES2677945T3 (es) * | 2009-08-25 | 2018-08-07 | Servicio Andaluz De Salud | Producción de tejidos artificiales mediante ingeniería tisular utilizando biomateriales de fibrina y agarosa |
| WO2012045083A2 (en) | 2010-10-02 | 2012-04-05 | The Regents Of The University Of California | Minimizing intestinal dysfunction |
| WO2012085298A1 (es) * | 2010-12-22 | 2012-06-28 | Universidad De Valladolid (40%) | Gel de fibrina que contiene células del limbo esclerocorneal y su uso en bioingeniería de la superficie ocular |
| FR2999083B1 (fr) * | 2012-12-12 | 2015-01-23 | Univ Nantes | Pansement contenant des fibroblastes et des keratinocytes foetaux |
| JP6258968B2 (ja) | 2012-12-28 | 2018-01-10 | ダウ グローバル テクノロジーズ エルエルシー | コーティング組成物およびそれから作製される物品 |
| US9422444B2 (en) | 2012-12-28 | 2016-08-23 | Dow Global Technologies Llc | Coating compositions |
| US10010658B2 (en) | 2013-05-10 | 2018-07-03 | Smith & Nephew Plc | Fluidic connector for irrigation and aspiration of wounds |
| US20160213714A1 (en) * | 2015-01-23 | 2016-07-28 | Everon Biosciences, Inc. | Induction of cellular senescence for tissue therapies |
| GB201504124D0 (en) | 2015-03-11 | 2015-04-22 | Proqr Therapeutics B V | Oligonucleotides |
| RU2657202C1 (ru) * | 2017-06-13 | 2018-06-08 | Государственное бюджетное учреждение здравоохранения "Научно-исследовательский институт - краевая клиническая больница имени профессора С.В. Очаповского" Министерства Здравоохранения Краснодарского края (ГБУЗ "НИИ-ККБ N 1 им. проф. Очаповского" Минздрава Краснодарского края | Способ кожной аутопластики |
| RU2702152C1 (ru) * | 2018-11-15 | 2019-10-04 | Государственное бюджетное учреждение здравоохранения "Научно-исследовательский институт - краевая клиническая больница N 1 имени профессора С.В. Очаповского" Министерства здравоохранения Краснодарского края (ГБУЗ "НИИ-ККБ N 1 им. проф. Очаповского" Минздрава Краснодарского края) | Способ лечения донорской раны живота |
| US11654057B2 (en) | 2020-04-09 | 2023-05-23 | Bio 54, Llc | Devices for bleeding reduction and methods of making and using the same |
| CN111614010B (zh) * | 2020-05-12 | 2021-04-13 | 中国长江电力股份有限公司 | 500kV焊接型GIL管道母线分解检修方法 |
| JP7486227B2 (ja) * | 2020-06-30 | 2024-05-17 | 株式会社 レオロジー機能食品研究所 | 皮膚改善用組成物 |
| CN113967128B (zh) * | 2020-07-24 | 2023-04-25 | 烟台蓝创生物技术有限公司 | 一种去除海藻酸盐敷料中热原的方法 |
| US11642324B1 (en) | 2022-03-01 | 2023-05-09 | Bio 54, Llc | Topical tranexamic acid compositions and methods of use thereof |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RO106655B1 (ro) | 1986-04-18 | 1993-06-30 | Marrow Tech Inc | Sistem tridimensional de cultura de tesuturi si celule |
| FR2597499A1 (fr) | 1986-04-18 | 1987-10-23 | Merieux Inst | Procede de culture microbiologique sur supports de collagene, supports pour ce procede et produits obtenus |
| US4963489A (en) | 1987-04-14 | 1990-10-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
| US4837379A (en) | 1988-06-02 | 1989-06-06 | Organogenesis Inc. | Fibrin-collagen tissue equivalents and methods for preparation thereof |
| US7229959B1 (en) * | 1990-11-27 | 2007-06-12 | The American National Red Cross | Supplemented fibrin matrix delivery systems |
| DE4127570A1 (de) | 1991-08-21 | 1993-02-25 | Battelle Institut E V | Verfahren zur lokalen antibakteriellen therapie von wunden |
| RU2023424C1 (ru) | 1993-01-13 | 1994-11-30 | Научно-производственный центр трансплантации и культивирования тканей | Способ лечения раны |
| US5591444A (en) | 1995-07-28 | 1997-01-07 | Isolagen Technologies, Inc. | Use of autologous dermal fibroblasts for the repair of skin and soft tissue defects |
| AU6662698A (en) | 1997-02-20 | 1998-09-09 | Gregory S. Keller | Augmentation and repair of dermal, subcutaneous, and vocal cord tissue defects |
| JP3333108B2 (ja) | 1997-04-08 | 2002-10-07 | 学校法人東海大学 | 上皮性組織移植片およびその製造方法 |
| DE69808291T2 (de) | 1997-06-26 | 2003-06-26 | Smith & Nephew Plc, London | Wundverbände mit biologisch abbaubarer Zellverankerungsschicht |
| US6150505A (en) * | 1997-09-19 | 2000-11-21 | Hadasit Medical Research Services & Development Ltd. | Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII |
| AU2798599A (en) * | 1998-02-27 | 1999-09-15 | Bioelastics Research Ltd. | Injectable implants for tissue augmentation and restoration |
| WO1999051164A1 (en) | 1998-04-03 | 1999-10-14 | Reprogenesis, Inc. | Soft tissue reconstructor and method of use |
| US6432710B1 (en) * | 1998-05-22 | 2002-08-13 | Isolagen Technologies, Inc. | Compositions for regenerating tissue that has deteriorated, and methods for using such compositions |
| CA2334364C (en) | 1998-06-05 | 2011-01-04 | Organogenesis Inc. | Bioengineered flat sheet graft prostheses |
| US6699287B2 (en) * | 1998-09-24 | 2004-03-02 | Korea Atomic Energy Research Institute | Dermal scaffold using alkaline pre-treated chitosan matrix or alkaline pre-treated chitosan and alkaline pre-treated collagen mixed matrix |
| US6124522A (en) * | 1998-11-24 | 2000-09-26 | Schroeder; Mark R. | Packaging for adhesive-sided articles to allow one-handed application |
| CA2351511A1 (en) | 1998-11-25 | 2000-06-02 | Jan Marcussen | A layered product ready for non-touch application and a method for producing such a product |
| RU2195889C2 (ru) | 1999-05-24 | 2003-01-10 | Парамонов Борис Алексеевич | Способ дермабразии |
| US6733530B1 (en) * | 1999-08-02 | 2004-05-11 | Eric Sun-Yin Chan | Material and method for engraftment of a composite biocompatible skin graft on the neodermis of artificial skin |
| US6699470B1 (en) * | 1999-10-12 | 2004-03-02 | Massachusetts Institute Of Technology | Mesh-gel constructs for cell delivery containing enzymes and/or enzyme inhibitors to control gel degradation |
| JP2003517858A (ja) | 1999-11-05 | 2003-06-03 | ジェリジーン メディカル コーポレーション | 老齢関連の軟組織の欠陥の増強と修復 |
| US6623728B2 (en) * | 2000-06-30 | 2003-09-23 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Cosmetic skin care compositions and containing gum mastic |
| DE10041468C1 (de) * | 2000-08-23 | 2002-03-07 | Surface Care Gmbh | Hautmatrix zur Abdeckung und Regenerierung verletzter Hautpartien sowie Verfahren zu ihrer Herstellung |
| US7144729B2 (en) * | 2000-09-01 | 2006-12-05 | Dfb Pharmaceuticals, Inc. | Methods and compositions for tissue regeneration |
| AU9109201A (en) * | 2000-09-18 | 2002-03-26 | Organogenesis Inc | Methods for treating a patient using a bioengineered flat sheet graft prostheses |
| ES2173812B1 (es) * | 2001-03-01 | 2003-12-16 | Ct Investig Energeticas Ciemat | Dermis artificial y metodo de obtencion. |
| GB0105899D0 (en) * | 2001-03-09 | 2001-04-25 | Intercytex Ltd | Fibrosis reduction treatment |
| DE10116362A1 (de) * | 2001-04-02 | 2002-10-10 | Biotissue Technologies Ag | Zwei-Komponenten Zusammensetzungen zur in situ Herstellung v. Fibroblasten und Keratinozyten umfassenden Zelltransplantaten |
| US20030069639A1 (en) * | 2001-04-14 | 2003-04-10 | Tom Sander | Methods and compositions for repair or replacement of joints and soft tissues |
| US20040031067A1 (en) * | 2001-10-11 | 2004-02-12 | Meenhard Herlyn | Regulation of human skin healing |
| US20030166274A1 (en) | 2001-11-15 | 2003-09-04 | Hewitt Charles W. | Three-dimensional matrix for producing living tissue equivalents |
| AU2003226201A1 (en) | 2002-04-02 | 2003-10-20 | William Marsh Rice University | Redifferentiated cells for repairing cartilage defects |
| DE10217779A1 (de) * | 2002-04-18 | 2003-11-13 | Co Don Ag | Konservierte Gewebematrix eines Hohlorganes, insbesondere eines Blutgefäßes, Verfahren zur Herstellung und Verwendung dieser |
| US20040082063A1 (en) * | 2002-10-18 | 2004-04-29 | Reliance Life Sciences Pvt. Ltd. | Tissue-like organization of cells and macroscopic tissue-like constructs, generated by macromass culture of cells, and the method of macromass culture |
| US8765169B2 (en) | 2004-02-13 | 2014-07-01 | Smith & Nephew, Inc. | Wound healing profile |
| RU2273457C2 (ru) | 2004-06-01 | 2006-04-10 | Сергей Степанович Кузнецов | Способ лечения грыж передней брюшной стенки |
-
2005
- 2005-02-14 US US10/589,150 patent/US8765169B2/en not_active Expired - Fee Related
- 2005-02-14 CA CA2556098A patent/CA2556098C/en not_active Expired - Fee Related
- 2005-02-14 WO PCT/GB2005/000523 patent/WO2005079822A2/en not_active Ceased
- 2005-02-14 CA CA002555233A patent/CA2555233A1/en not_active Abandoned
- 2005-02-14 EP EP05708330A patent/EP1718317A1/en not_active Withdrawn
- 2005-02-14 AU AU2005215213A patent/AU2005215213C1/en not_active Ceased
- 2005-02-14 US US10/589,227 patent/US9526746B2/en not_active Expired - Fee Related
- 2005-02-14 EP EP05764678.8A patent/EP1718318B1/en not_active Expired - Lifetime
- 2005-02-14 JP JP2006552692A patent/JP5706058B2/ja not_active Expired - Fee Related
- 2005-02-14 AU AU2005215211A patent/AU2005215211B2/en not_active Ceased
- 2005-02-14 WO PCT/GB2005/000511 patent/WO2005079821A1/en not_active Ceased
-
2012
- 2012-06-14 JP JP2012135016A patent/JP6141603B2/ja not_active Expired - Fee Related
-
2014
- 2014-05-15 US US14/279,057 patent/US9248153B2/en not_active Expired - Fee Related
- 2014-12-22 JP JP2014258639A patent/JP6141821B2/ja not_active Expired - Fee Related
-
2015
- 2015-04-02 JP JP2015075997A patent/JP2015134815A/ja active Pending
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