JP2007518680A - ジ−アリール尿素化合物の製造方法 - Google Patents

ジ−アリール尿素化合物の製造方法 Download PDF

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Publication number
JP2007518680A
JP2007518680A JP2006518643A JP2006518643A JP2007518680A JP 2007518680 A JP2007518680 A JP 2007518680A JP 2006518643 A JP2006518643 A JP 2006518643A JP 2006518643 A JP2006518643 A JP 2006518643A JP 2007518680 A JP2007518680 A JP 2007518680A
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JP
Japan
Prior art keywords
alkyl
compound
formula
alkoxy
hours
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JP2006518643A
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English (en)
Japanese (ja)
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JP2007518680A5 (https=
Inventor
ニザー ハダッド
シュードン ウェイ
クリス ヒュー セナナヤケ
ジングア シュー
ネイサン イー
Original Assignee
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド
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Publication of JP2007518680A publication Critical patent/JP2007518680A/ja
Publication of JP2007518680A5 publication Critical patent/JP2007518680A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2006518643A 2003-06-30 2004-06-11 ジ−アリール尿素化合物の製造方法 Pending JP2007518680A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48372003P 2003-06-30 2003-06-30
PCT/US2004/018694 WO2005005396A1 (en) 2003-06-30 2004-06-11 Process of making di-aryl urea compounds

Publications (2)

Publication Number Publication Date
JP2007518680A true JP2007518680A (ja) 2007-07-12
JP2007518680A5 JP2007518680A5 (https=) 2007-08-23

Family

ID=34061980

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006518643A Pending JP2007518680A (ja) 2003-06-30 2004-06-11 ジ−アリール尿素化合物の製造方法

Country Status (6)

Country Link
US (1) US7265222B2 (https=)
EP (1) EP1644341A1 (https=)
JP (1) JP2007518680A (https=)
CN (1) CN1812975A (https=)
CA (1) CA2530776A1 (https=)
WO (1) WO2005005396A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563115B2 (en) 2008-08-12 2013-10-22 Xerox Corporation Protective coatings for solid inkjet applications
US8191992B2 (en) 2008-12-15 2012-06-05 Xerox Corporation Protective coatings for solid inkjet applications
AU2014246866B2 (en) 2013-04-02 2018-05-10 Oxular Acquisitions Limited Kinase inhibitor
CA2934199A1 (en) 2013-12-20 2015-06-25 Respivert Limited Urea derivatives useful as kinase inhibitors
MA40774A (fr) 2014-10-01 2017-08-08 Respivert Ltd Dérivés de diaryle-urée en tant qu'inhibiteurs de kinase p38
EA201892213A1 (ru) 2016-04-06 2019-05-31 Топайверт Фарма Лимитед Ингибиторы киназ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002083628A1 (en) * 2001-04-13 2002-10-24 Boehringer Ingelheim Pharmaceuticals, Inc. 1,4-disubstituted benzo-fused compounds
JP2004530690A (ja) * 2001-05-16 2004-10-07 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド 抗炎症性薬剤として有用なジアリールウレア誘導体
EP1549621A1 (en) * 2002-08-08 2005-07-06 Boehringer Ingelheim Pharmaceuticals Inc. Fluorinated phenyl-naphthalenyl-urea compounds as inhibitors of cytokines involved in inflammatory processes

Also Published As

Publication number Publication date
CN1812975A (zh) 2006-08-02
US20040266767A1 (en) 2004-12-30
CA2530776A1 (en) 2005-01-20
EP1644341A1 (en) 2006-04-12
WO2005005396A1 (en) 2005-01-20
US7265222B2 (en) 2007-09-04

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