JP2007517850A5 - - Google Patents
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- Publication number
- JP2007517850A5 JP2007517850A5 JP2006548403A JP2006548403A JP2007517850A5 JP 2007517850 A5 JP2007517850 A5 JP 2007517850A5 JP 2006548403 A JP2006548403 A JP 2006548403A JP 2006548403 A JP2006548403 A JP 2006548403A JP 2007517850 A5 JP2007517850 A5 JP 2007517850A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- independently selected
- chiral
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 6
- 125000000753 cycloalkyl group Chemical group 0.000 claims 4
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 125000001072 heteroaryl group Chemical group 0.000 claims 3
- 125000005842 heteroatom Chemical group 0.000 claims 3
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- 229910052760 oxygen Chemical group 0.000 claims 3
- 239000001301 oxygen Chemical group 0.000 claims 3
- 239000000758 substrate Substances 0.000 claims 3
- 239000011593 sulfur Substances 0.000 claims 3
- 229910052717 sulfur Inorganic materials 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 229940126062 Compound A Drugs 0.000 claims 1
- 239000007818 Grignard reagent Substances 0.000 claims 1
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 claims 1
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Natural products P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- RBFQJDQYXXHULB-UHFFFAOYSA-N arsane Chemical class [AsH3] RBFQJDQYXXHULB-UHFFFAOYSA-N 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 1
- 125000006310 cycloalkyl amino group Chemical group 0.000 claims 1
- 150000004795 grignard reagents Chemical class 0.000 claims 1
- 125000005241 heteroarylamino group Chemical group 0.000 claims 1
- 125000005553 heteroaryloxy group Chemical group 0.000 claims 1
- 125000002950 monocyclic group Chemical group 0.000 claims 1
- 150000002900 organolithium compounds Chemical class 0.000 claims 1
- 150000003003 phosphines Chemical class 0.000 claims 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0400720.9A GB0400720D0 (en) | 2004-01-14 | 2004-01-14 | Novel ferrocene-based phosphorus chiral phosphines |
| PCT/GB2005/000125 WO2005068478A1 (en) | 2004-01-14 | 2005-01-14 | Process for the production of asymmetric transformation catalysts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007517850A JP2007517850A (ja) | 2007-07-05 |
| JP2007517850A5 true JP2007517850A5 (enExample) | 2008-02-28 |
Family
ID=31726125
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006548397A Pending JP2007517849A (ja) | 2004-01-14 | 2005-01-14 | メタロセン基体のキラルホスフィンまたはアルシンリガンド |
| JP2006548403A Pending JP2007517850A (ja) | 2004-01-14 | 2005-01-14 | 不斉変換触媒を製造するための方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006548397A Pending JP2007517849A (ja) | 2004-01-14 | 2005-01-14 | メタロセン基体のキラルホスフィンまたはアルシンリガンド |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7994355B2 (enExample) |
| EP (2) | EP1725570B1 (enExample) |
| JP (2) | JP2007517849A (enExample) |
| CN (2) | CN1914218A (enExample) |
| AT (2) | ATE404573T1 (enExample) |
| AU (2) | AU2005205224B2 (enExample) |
| CA (2) | CA2553607A1 (enExample) |
| DE (2) | DE602005013062D1 (enExample) |
| ES (2) | ES2313282T3 (enExample) |
| GB (4) | GB0400720D0 (enExample) |
| WO (2) | WO2005068477A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0400720D0 (en) * | 2004-01-14 | 2004-02-18 | Stylacats Ltd | Novel ferrocene-based phosphorus chiral phosphines |
| CN100577673C (zh) * | 2004-05-07 | 2010-01-06 | 优美科两合公司 | 用于均相、对映选择性氢化催化剂的二茂铁基配体 |
| US6906213B1 (en) * | 2004-06-25 | 2005-06-14 | Eastman Chemical Company | Preparation of aminophosphines |
| US6906212B1 (en) * | 2004-06-25 | 2005-06-14 | Eastman Chemical Company | Phosphine-phosphoramidite compounds |
| US20060135804A1 (en) * | 2004-12-21 | 2006-06-22 | Boaz Neil W | Tetradentate ligands and metal complexes thereof for asymmetric catalysis |
| GB0500700D0 (en) * | 2005-01-14 | 2005-02-23 | Stylacats Ltd | Process for the manufacture of 2-alkyl-3-phenylpropionic acids and alcohols |
| GB0500702D0 (en) * | 2005-01-14 | 2005-02-23 | Stylacats Ltd | Novel metallocene-based phosphorus chiral phosphines |
| CN101421285B (zh) * | 2006-04-12 | 2013-02-06 | 索尔维亚斯股份公司 | 二茂铁二膦 |
| US8008529B2 (en) * | 2006-05-23 | 2011-08-30 | Solvias Ag | Chiral ligands used in transition metal catalysts for asymmetric addition reactions especially hydrogenation |
| JP5232989B2 (ja) * | 2006-07-18 | 2013-07-10 | 国立大学法人豊橋技術科学大学 | 光学活性２，６−ビスアミノメチルピリジン誘導体とその製造方法およびその使用 |
| JP5493346B2 (ja) * | 2008-12-11 | 2014-05-14 | 東ソー株式会社 | フェロセン誘導体およびその用途 |
| EP2519100B1 (en) | 2009-12-29 | 2017-03-15 | Mapi Pharma Limited | Intermediate compounds and processes for the preparation of tapentadol and related compounds |
| CN102775418B (zh) * | 2012-06-11 | 2014-12-24 | 中国人民解放军第四军医大学 | 新型手性季铵盐相转移催化剂的合成及应用 |
| CN104592313B (zh) * | 2014-12-30 | 2017-08-25 | 陕西师范大学 | 基于二茂铁的双功能氢键有机催化剂及其制备方法和应用 |
| CN104861001B (zh) * | 2015-06-11 | 2017-08-04 | 河南省科学院化学研究所有限公司 | 一种二茂铁双膦配体的制备方法 |
| EP3121180B1 (de) * | 2015-07-23 | 2018-09-12 | Evonik Degussa GmbH | Butyl-verbrückte diphosphinliganden für die alkoxycarbonylierung |
| PT3272759T (pt) * | 2016-07-19 | 2019-07-17 | Evonik Degussa Gmbh | Ligandos de 1,1¿-bis(fosfino)ferroceno para a alcoxicarbonilação |
| CN109078653A (zh) * | 2018-10-08 | 2018-12-25 | 浙江工业大学上虞研究院有限公司 | 手性二茂铁磷酸催化剂及其在不对称Friedel-Crafts反应中的应用 |
| CN112824422B (zh) * | 2019-11-21 | 2023-01-13 | 中国科学院大连化学物理研究所 | 一种手性二茂铁-吲哚双膦配体及其制备方法和其应用 |
| CN114560893B (zh) * | 2022-03-16 | 2024-02-06 | 中国科学院上海有机化学研究所 | 平面手性茂金属化合物、其合成方法及应用 |
| CN116178455B (zh) * | 2023-04-26 | 2023-08-18 | 江苏欣诺科催化剂股份有限公司 | 一种二茂铁类手性膦配体的制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG42938A1 (en) * | 1993-02-26 | 1997-10-17 | Ciba Geigy Ag | Ferrocenc diphosphines as ligands for homogeneous catalysts |
| CA2122511A1 (en) * | 1993-05-14 | 1994-11-15 | John Mcgarrity | Asymmetric hydrogenation of furoimidazole derivatives |
| DE59408655D1 (de) * | 1993-10-01 | 1999-09-30 | Novartis Ag | Mit Fluoralkyl substituierte Ferrocenyldiphosphine als Liganden für homogene Katalysatoren |
| DE69603466T2 (de) * | 1995-04-11 | 1999-11-18 | Novartis Ag, Basel | Dihalogenierte ferrocene und verfahren zu deren herstellung |
| ES2183036T3 (es) | 1996-04-25 | 2003-03-16 | Hoechst Ag | 2,2' - disustituidos-ferrocenos 2,2`-disustituidos y 1-fosfino-ferrocenos 1`,2-disustituidos, procedimiento para su preparacion, su utilizacion, asi como complejos de metales de transicion que los contienen,. |
| ES2170942T3 (es) | 1996-10-07 | 2002-08-16 | Syngenta Participations Ag | Ferrocenilos quirales. |
| EP0967015B1 (de) * | 1998-06-19 | 2005-01-12 | Degussa AG | Verwendung von Ferrocenylliganden zur katalytischen enantioselektiven Hydrierung |
| DE19840279A1 (de) | 1998-09-04 | 2000-03-09 | Studiengesellschaft Kohle Mbh | Neue chirale Diphosphonite auf Ferrocenbasis für die asymmetrische Katalyse |
| DE19952348A1 (de) * | 1998-12-19 | 2000-06-21 | Degussa | Liganden und Komplexe zur enantioselektiven Hydrierung |
| US6258979B1 (en) * | 1999-11-22 | 2001-07-10 | Henri Kagan | Chiral ferrocene phosphines active in asymmetric catalysis |
| US6194593B1 (en) * | 2000-01-28 | 2001-02-27 | Nippon Chemical Industrial Co., Ltd. | 1, 2-bis(dialkylphosphino) benzene derivates having optical activites, process for producing same, and rhodium metal complexes containing same as ligands |
| JP4754753B2 (ja) * | 2000-02-10 | 2011-08-24 | ザ ペン ステイト リサーチ ファンデーション | キラルフェロセンホスフィン及び不斉触媒反応におけるその使用 |
| US6777567B2 (en) | 2000-07-03 | 2004-08-17 | Solvias Ag | Ferrocenyl diphosphines and their use |
| US6590115B2 (en) * | 2000-09-29 | 2003-07-08 | Eastman Chemical Company | Phosphino-aminophosphines |
| AU2002362688A1 (en) * | 2001-10-05 | 2003-04-22 | Solvias Ag | Ligands for asymmetric reactions |
| DE10211250A1 (de) * | 2002-03-13 | 2003-10-23 | Degussa | Ferrocenylliganden und ihre Verwendung in der Katalyse |
| DE10219490A1 (de) | 2002-04-30 | 2003-11-13 | Degussa | Ferrocenylliganden und ein Verfahren zur Herstellung solcher Liganden |
| GB0400720D0 (en) * | 2004-01-14 | 2004-02-18 | Stylacats Ltd | Novel ferrocene-based phosphorus chiral phosphines |
| EP1765840A1 (en) * | 2004-07-05 | 2007-03-28 | Solvias AG | Tetradentate ferrocene ligands and their use |
-
2004
- 2004-01-14 GB GBGB0400720.9A patent/GB0400720D0/en not_active Ceased
-
2005
- 2005-01-14 CA CA002553607A patent/CA2553607A1/en not_active Abandoned
- 2005-01-14 WO PCT/GB2005/000112 patent/WO2005068477A1/en not_active Ceased
- 2005-01-14 DE DE602005013062T patent/DE602005013062D1/de not_active Expired - Lifetime
- 2005-01-14 US US10/586,287 patent/US7994355B2/en not_active Expired - Fee Related
- 2005-01-14 CN CNA2005800037221A patent/CN1914218A/zh active Pending
- 2005-01-14 WO PCT/GB2005/000125 patent/WO2005068478A1/en not_active Ceased
- 2005-01-14 CA CA002553608A patent/CA2553608A1/en not_active Abandoned
- 2005-01-14 JP JP2006548397A patent/JP2007517849A/ja active Pending
- 2005-01-14 GB GB0500701A patent/GB2410950B/en not_active Expired - Fee Related
- 2005-01-14 AU AU2005205224A patent/AU2005205224B2/en not_active Ceased
- 2005-01-14 GB GB0500704A patent/GB2410951B/en not_active Expired - Fee Related
- 2005-01-14 CN CNA2005800037217A patent/CN1914217A/zh active Pending
- 2005-01-14 AU AU2005205229A patent/AU2005205229B2/en not_active Ceased
- 2005-01-14 US US10/586,204 patent/US20080281106A1/en not_active Abandoned
- 2005-01-14 JP JP2006548403A patent/JP2007517850A/ja active Pending
- 2005-01-14 ES ES05701893T patent/ES2313282T3/es not_active Expired - Lifetime
- 2005-01-14 AT AT05701893T patent/ATE404573T1/de active
- 2005-01-14 EP EP05701893A patent/EP1725570B1/en not_active Expired - Lifetime
- 2005-01-14 ES ES05701880T patent/ES2323717T3/es not_active Expired - Lifetime
- 2005-01-14 DE DE602005008917T patent/DE602005008917D1/de not_active Expired - Lifetime
- 2005-01-14 EP EP05701880A patent/EP1709054B1/en not_active Expired - Lifetime
- 2005-01-14 AT AT05701880T patent/ATE424404T1/de active
-
2009
- 2009-03-26 GB GBGB0905212.7A patent/GB0905212D0/en not_active Ceased
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