JP2007517785A - 慢性静脈不全の治療のための赤ブドウの葉の水性抽出物及び利尿剤を含む組成物 - Google Patents
慢性静脈不全の治療のための赤ブドウの葉の水性抽出物及び利尿剤を含む組成物 Download PDFInfo
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- BJRNKVDFDLYUGJ-RMPHRYRLSA-N hydroquinone O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 description 1
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- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 1
- 229960000869 magnesium oxide Drugs 0.000 description 1
- 235000012245 magnesium oxide Nutrition 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 229960003390 magnesium sulfate Drugs 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- RXMQCXCANMAVIO-CEOVSRFSSA-L magnesium;(2s)-2-amino-4-hydroxy-4-oxobutanoate Chemical compound [H+].[H+].[Mg+2].[O-]C(=O)[C@@H](N)CC([O-])=O.[O-]C(=O)[C@@H](N)CC([O-])=O RXMQCXCANMAVIO-CEOVSRFSSA-L 0.000 description 1
- MYUGVHJLXONYNC-QHTZZOMLSA-L magnesium;(2s)-2-amino-5-hydroxy-5-oxopentanoate Chemical compound [Mg+2].[O-]C(=O)[C@@H](N)CCC(O)=O.[O-]C(=O)[C@@H](N)CCC(O)=O MYUGVHJLXONYNC-QHTZZOMLSA-L 0.000 description 1
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 1
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- 235000011056 potassium acetate Nutrition 0.000 description 1
- GRLPQNLYRHEGIJ-UHFFFAOYSA-J potassium aluminium sulfate Chemical compound [Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRLPQNLYRHEGIJ-UHFFFAOYSA-J 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 235000011181 potassium carbonates Nutrition 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000001508 potassium citrate Substances 0.000 description 1
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 description 1
- 239000004224 potassium gluconate Substances 0.000 description 1
- 235000013926 potassium gluconate Nutrition 0.000 description 1
- 229960003189 potassium gluconate Drugs 0.000 description 1
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 description 1
- 229910052939 potassium sulfate Inorganic materials 0.000 description 1
- 235000011151 potassium sulphates Nutrition 0.000 description 1
- HQEROMHPIOLGCB-DFWYDOINSA-M potassium;(2s)-2-aminopentanedioate;hydron Chemical compound [K+].[O-]C(=O)[C@@H](N)CCC(O)=O HQEROMHPIOLGCB-DFWYDOINSA-M 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
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- 235000021251 pulses Nutrition 0.000 description 1
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- OVSQVDMCBVZWGM-QSOFNFLRSA-N quercetin 3-O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OVSQVDMCBVZWGM-QSOFNFLRSA-N 0.000 description 1
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- 150000003839 salts Chemical class 0.000 description 1
- 239000010018 saw palmetto extract Substances 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 238000007632 sclerotherapy Methods 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- RSIJVJUOQBWMIM-UHFFFAOYSA-L sodium sulfate decahydrate Chemical compound O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O RSIJVJUOQBWMIM-UHFFFAOYSA-L 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
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- PLSARIKBYIPYPF-UHFFFAOYSA-H trimagnesium dicitrate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O PLSARIKBYIPYPF-UHFFFAOYSA-H 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03029900A EP1550451A1 (en) | 2003-12-29 | 2003-12-29 | Composition comprising an aqueous extract of red vine leaves and a diuretic for the treatment of chronic venous insufficiencies |
| PCT/EP2004/014458 WO2005063270A1 (en) | 2003-12-29 | 2004-12-18 | Composition comprising an aqueous extract of red vine leaves and a diuretic for the treatment of chronic venous insufficiences |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007517785A true JP2007517785A (ja) | 2007-07-05 |
| JP2007517785A5 JP2007517785A5 (https=) | 2008-02-14 |
Family
ID=34560172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006546018A Pending JP2007517785A (ja) | 2003-12-29 | 2004-12-18 | 慢性静脈不全の治療のための赤ブドウの葉の水性抽出物及び利尿剤を含む組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050142236A1 (https=) |
| EP (2) | EP1550451A1 (https=) |
| JP (1) | JP2007517785A (https=) |
| BR (1) | BRPI0418293A (https=) |
| CA (1) | CA2548357A1 (https=) |
| MX (1) | MXPA06007499A (https=) |
| RU (1) | RU2006127295A (https=) |
| WO (1) | WO2005063270A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009165410A (ja) * | 2008-01-16 | 2009-07-30 | Yoshihide Hamano | 葡萄葉茶及びその製造方法 |
| JP2014159379A (ja) * | 2013-02-19 | 2014-09-04 | Ss Pharmaceut Co Ltd | むくみ治療用経口組成物 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001122791A (ja) * | 1999-10-20 | 2001-05-08 | Boehringer Ingelheim Internatl Gmbh | 下肢の慢性静脈不全の軽減および予防のための赤色ブドウ樹葉の水性抽出物よりなる食事補強剤 |
| EP1550450A1 (en) * | 2003-12-29 | 2005-07-06 | Boehringer Ingelheim International GmbH | Composition comprising an aqueous extract of red vine leaves and a blood circulating-improving agent for the treatment of chronic venous insufficiencies |
| JP2007523110A (ja) * | 2004-02-19 | 2007-08-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 赤ブドウ葉の抽出物および抗炎症剤を含む、慢性静脈疾患を治療するための組成物 |
| ES2597104T3 (es) | 2007-04-19 | 2017-01-13 | Mary Kay, Inc. | Composiciones que contienen extracto de magnolia |
| WO2008152624A2 (en) * | 2007-06-15 | 2008-12-18 | Antaki Center For Herbal Medicine Ltd | Herbal energy-enhancing formulation |
| WO2009027382A2 (de) * | 2007-08-31 | 2009-03-05 | Boehringer Ingelheim International Gmbh | Sprühfähige zusammensetzung enthaltend extrakt aus rotem weinlaub |
| ITTO20070861A1 (it) * | 2007-11-29 | 2009-05-30 | Vincenzo Cianni | Integratore alimentare naturale comprendente principi attivi del frutto del limone (citrus limonum) e delle foglie di vite rossa (vitis vinifera) |
| DE102008012908A1 (de) * | 2008-03-06 | 2009-09-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Methode zum anti-inflammatorischen und anti-ödematösen Schutz von explantiertem biologischen Material bis zu seiner Transplantation in Patienten |
| RU2563190C2 (ru) * | 2012-06-14 | 2015-09-20 | Открытое Акционерное Общество "Татхимфармпрераты" | Лекарственное средство на основе сухих экстрактов лекарственных растений и способ его получения (варианты) |
| WO2014175518A1 (ko) * | 2013-04-23 | 2014-10-30 | 한국식품연구원 | 마테 추출물을 유효성분으로 포함하는 통증의 완화, 예방 또는 치료용 조성물 및 시료의 통증 완화, 예방 또는 치료 효능에 대한 평가방법 |
| KR101483990B1 (ko) | 2013-04-23 | 2015-01-20 | 한국식품연구원 | 시료의 통증 완화, 예방 또는 치료 효능에 대한 평가방법 |
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| US6210680B1 (en) * | 1999-06-11 | 2001-04-03 | Univera Pharmaceuticals, Inc. | Method for the prevention and treatment of chronic venous insufficiency |
| JP2003511476A (ja) * | 1999-10-20 | 2003-03-25 | ベーリンガー インゲルハイム インターナシヨナル ゲゼルシヤフト ミツト ベシユレンクテル ハフツンク | 赤色ブドウ樹葉の抽出物を用いる慢性静脈不全の治療方法 |
| WO2003080063A1 (en) * | 2002-03-22 | 2003-10-02 | Daiichi Suntory Pharma Co., Ltd. | PREVENTIVES OR REMEDIES FOR DISEAES CAUSED BY eNOS EXPRESSION |
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| NL278161A (https=) * | 1961-05-13 | |||
| JPS55111791A (en) * | 1979-02-22 | 1980-08-28 | Japan Synthetic Rubber Co Ltd | Antitumor substance |
| AU5574101A (en) * | 2000-04-28 | 2001-11-12 | Univ Emory | Decellularized vascular prostheses |
| US20020192834A1 (en) * | 2001-03-23 | 2002-12-19 | Sand Bruce J. | Analysis of caffeine |
| ITGE20020026A1 (it) * | 2002-03-25 | 2003-09-25 | Segre Silvia Perella | Composto da impiegare nel trattamento scleroterapico,nell'insufficienza venosa e nelle alterazioni del microcircolo. |
| US20040146539A1 (en) * | 2003-01-24 | 2004-07-29 | Gupta Shyam K. | Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits |
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2003
- 2003-12-29 EP EP03029900A patent/EP1550451A1/en not_active Withdrawn
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2004
- 2004-12-02 US US11/002,054 patent/US20050142236A1/en not_active Abandoned
- 2004-12-18 CA CA002548357A patent/CA2548357A1/en not_active Abandoned
- 2004-12-18 EP EP04804059A patent/EP1708729A1/en not_active Withdrawn
- 2004-12-18 WO PCT/EP2004/014458 patent/WO2005063270A1/en not_active Ceased
- 2004-12-18 MX MXPA06007499A patent/MXPA06007499A/es not_active Application Discontinuation
- 2004-12-18 JP JP2006546018A patent/JP2007517785A/ja active Pending
- 2004-12-18 BR BRPI0418293-6A patent/BRPI0418293A/pt not_active Application Discontinuation
- 2004-12-18 RU RU2006127295/15A patent/RU2006127295A/ru not_active Application Discontinuation
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US6210680B1 (en) * | 1999-06-11 | 2001-04-03 | Univera Pharmaceuticals, Inc. | Method for the prevention and treatment of chronic venous insufficiency |
| JP2003511476A (ja) * | 1999-10-20 | 2003-03-25 | ベーリンガー インゲルハイム インターナシヨナル ゲゼルシヤフト ミツト ベシユレンクテル ハフツンク | 赤色ブドウ樹葉の抽出物を用いる慢性静脈不全の治療方法 |
| WO2003080063A1 (en) * | 2002-03-22 | 2003-10-02 | Daiichi Suntory Pharma Co., Ltd. | PREVENTIVES OR REMEDIES FOR DISEAES CAUSED BY eNOS EXPRESSION |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009165410A (ja) * | 2008-01-16 | 2009-07-30 | Yoshihide Hamano | 葡萄葉茶及びその製造方法 |
| JP2014159379A (ja) * | 2013-02-19 | 2014-09-04 | Ss Pharmaceut Co Ltd | むくみ治療用経口組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1708729A1 (en) | 2006-10-11 |
| RU2006127295A (ru) | 2008-02-10 |
| MXPA06007499A (es) | 2006-08-31 |
| BRPI0418293A (pt) | 2007-05-02 |
| US20050142236A1 (en) | 2005-06-30 |
| CA2548357A1 (en) | 2005-07-14 |
| EP1550451A1 (en) | 2005-07-06 |
| WO2005063270A1 (en) | 2005-07-14 |
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