JP2007514752A - Ｇｌｐ−１医薬組成物 - Google Patents
Ｇｌｐ−１医薬組成物 Download PDFInfo
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- JP2007514752A JP2007514752A JP2006545462A JP2006545462A JP2007514752A JP 2007514752 A JP2007514752 A JP 2007514752A JP 2006545462 A JP2006545462 A JP 2006545462A JP 2006545462 A JP2006545462 A JP 2006545462A JP 2007514752 A JP2007514752 A JP 2007514752A
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- DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 title claims abstract description 48
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- ODKSFYDXXFIFQN-SCSAIBSYSA-N D-arginine Chemical group OC(=O)[C@H](N)CCCNC(N)=N ODKSFYDXXFIFQN-SCSAIBSYSA-N 0.000 claims description 6
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| US52993203P | 2003-12-16 | 2003-12-16 | |
| PCT/US2004/042389 WO2005058252A2 (en) | 2003-12-16 | 2004-12-16 | Glp-1 pharmaceutical compositions |
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| JP2007514752A true JP2007514752A (ja) | 2007-06-07 |
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| EP (1) | EP1694278A4 (enExample) |
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| AR (1) | AR047776A1 (enExample) |
| CA (1) | CA2550695A1 (enExample) |
| TW (1) | TWI353250B (enExample) |
| WO (1) | WO2005058252A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011520879A (ja) * | 2008-05-14 | 2011-07-21 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | ソマトスタチン−ドーパミンコンジュゲートの医薬組成物 |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050260259A1 (en) * | 2004-04-23 | 2005-11-24 | Bolotin Elijah M | Compositions for treatment with glucagon-like peptide, and methods of making and using the same |
| US7635463B2 (en) * | 2002-02-27 | 2009-12-22 | Pharmain Corporation | Compositions for delivery of therapeutics and other materials |
| ATE494010T1 (de) * | 2002-02-27 | 2011-01-15 | Pharmain Corp | Zusammensetzungen zur abgabe von therapeutika und anderen materialien und verfahren zu ihrer herstellung und verwendung |
| EP1904525A4 (en) * | 2005-06-30 | 2009-10-21 | Ipsen Pharma | GLP-1 PHARMACEUTICAL COMPOSITIONS |
| HRP20150186T1 (hr) | 2005-08-19 | 2015-05-22 | Amylin Pharmaceuticals, Llc. | Eksendin za lijeäśenje dijabetesa i smanjenje tjelesne težine |
| JP2009520040A (ja) | 2005-12-19 | 2009-05-21 | ファーマイン コーポレーション | 治療薬の送達のための疎水性コアの担体組成物、及び同担体組成物の作製法及び使用法 |
| NZ578126A (en) * | 2006-12-29 | 2012-05-25 | Ipsen Pharma Sas | Phamaceutical compostions comprising Glucagon-like peptide-1 (GLP-1) analog |
| AU2007340369C1 (en) * | 2006-12-29 | 2013-05-02 | Ipsen Pharma S.A.S. | GLP-1 pharmaceutical compositions |
| US7960336B2 (en) * | 2007-08-03 | 2011-06-14 | Pharmain Corporation | Composition for long-acting peptide analogs |
| US8563527B2 (en) * | 2007-08-20 | 2013-10-22 | Pharmain Corporation | Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same |
| EP2650006A1 (en) * | 2007-09-07 | 2013-10-16 | Ipsen Pharma S.A.S. | Analogues of exendin-4 and exendin-3 |
| US20090176892A1 (en) * | 2008-01-09 | 2009-07-09 | Pharmain Corporation | Soluble Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same |
| WO2009143285A2 (en) | 2008-05-21 | 2009-11-26 | Amylin Pharmaceuticals, Inc. | Exendins to lower cholestrol and triglycerides |
| WO2010016936A1 (en) * | 2008-08-07 | 2010-02-11 | Ipsen Pharma S.A.S. | Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide |
| CN102665401A (zh) | 2009-11-16 | 2012-09-12 | 益普生制药股份有限公司 | 黑皮质素受体配体的药物组合物 |
| WO2011115871A1 (en) * | 2010-03-15 | 2011-09-22 | Ipsen Pharma S.A.S. | Pharmaceutical compositions of growth hormone secretagogue receptor ligands |
| EP2384733B1 (de) | 2010-05-07 | 2016-07-27 | Ivoclar Vivadent AG | Antimikrobielle Dentalwerkstoffe |
| HK1213486A1 (zh) | 2012-11-01 | 2016-07-08 | Ipsen Pharma S.A.S. | 促生长素抑制素类似物及其二聚体 |
| TWI523863B (zh) | 2012-11-01 | 2016-03-01 | 艾普森藥品公司 | 體抑素－多巴胺嵌合體類似物 |
| EP3474820B1 (en) | 2017-08-24 | 2024-02-07 | Novo Nordisk A/S | Glp-1 compositions and uses thereof |
| PE20230819A1 (es) | 2020-02-18 | 2023-05-19 | Novo Nordisk As | Composiciones y usos de glp-1 |
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| JP2002531578A (ja) * | 1998-12-07 | 2002-09-24 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | Ｇｌｐ−１の類似体 |
| JP2002534450A (ja) * | 1999-01-14 | 2002-10-15 | アミリン・ファーマシューティカルズ，インコーポレイテッド | 新規なエキセンジンアゴニスト製剤とその投与方法 |
| JP2002538081A (ja) * | 1998-12-07 | 2002-11-12 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | Ｇｌｐ−１の類似体 |
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| WO2003002136A2 (en) * | 2001-06-28 | 2003-01-09 | Novo Nordisk A/S | Stable formulation of modified glp-1 |
| JP2003192698A (ja) * | 1990-01-24 | 2003-07-09 | Douglas I Buckley | 糖尿病治療に有用なｇｌｐ−１アナログ |
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| US4783441A (en) * | 1979-04-30 | 1988-11-08 | Hoechst Aktiengesellschaft | Aqueous protein solutions stable to denaturation |
| WO1987006941A1 (en) | 1986-05-05 | 1987-11-19 | The General Hospital Corporation | Insulinotropic hormone |
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| US6221958B1 (en) | 1993-01-06 | 2001-04-24 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides |
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| US6284727B1 (en) | 1993-04-07 | 2001-09-04 | Scios, Inc. | Prolonged delivery of peptides |
| US5705483A (en) | 1993-12-09 | 1998-01-06 | Eli Lilly And Company | Glucagon-like insulinotropic peptides, compositions and methods |
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| US5595760A (en) | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
| US5512549A (en) | 1994-10-18 | 1996-04-30 | Eli Lilly And Company | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
| US20010006943A1 (en) | 1994-12-23 | 2001-07-05 | Ejvind Jensen | Protracted GLP-1 compositions |
| US5980945A (en) | 1996-01-16 | 1999-11-09 | Societe De Conseils De Recherches Et D'applications Scientifique S.A. | Sustained release drug formulations |
| JP2001503963A (ja) | 1996-02-06 | 2001-03-27 | イーライ・リリー・アンド・カンパニー | 糖尿病治療 |
| US6264970B1 (en) | 1996-06-26 | 2001-07-24 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
| DE19629640C1 (de) | 1996-07-23 | 1997-08-28 | Metallgesellschaft Ag | Verfahren zur Herstellung von kristallinem D-Sorbit |
| US6458924B2 (en) * | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| ES2283025T3 (es) | 1996-08-30 | 2007-10-16 | Novo Nordisk A/S | Derivados de glp-1.1. |
| UA65549C2 (uk) | 1996-11-05 | 2004-04-15 | Елі Ліллі Енд Компані | Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція |
| US5981488A (en) | 1997-03-31 | 1999-11-09 | Eli Lillly And Company | Glucagon-like peptide-1 analogs |
| US6663899B2 (en) | 1997-06-13 | 2003-12-16 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
| US6380357B2 (en) | 1997-12-16 | 2002-04-30 | Eli Lilly And Company | Glucagon-like peptide-1 crystals |
| WO1999043705A1 (en) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | N-terminally truncated glp-1 derivatives |
| AU2610799A (en) | 1998-02-27 | 1999-09-15 | Novo Nordisk A/S | Glp-1 derivatives with helix-content exceeding 25 per cent, forming partially structured micellar-like aggregates |
| ATE230274T1 (de) | 1998-03-20 | 2003-01-15 | Takeda Chemical Industries Ltd | Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung |
| FR2776520B1 (fr) | 1998-03-25 | 2000-05-05 | Sod Conseils Rech Applic | Nouvelles compositions pharmaceutiques destinees a la liberation prolongee de peptides et leur procede de preparation |
| FR2777283B1 (fr) | 1998-04-10 | 2000-11-24 | Adir | Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| RU2205188C2 (ru) | 1998-06-30 | 2003-05-27 | Ново Нордиск А/С | Затравочные кристаллы для получения пептидов или протеинов |
| US6720407B1 (en) | 1998-08-28 | 2004-04-13 | Eli Lilly And Company | Method for administering insulinotropic peptides |
| AU5760900A (en) | 1999-06-25 | 2001-01-31 | Minimed, Inc. | Multiple agent diabetes therapy |
| US6541225B1 (en) * | 2000-01-26 | 2003-04-01 | Raven Biotechnologies, Inc. | Methods and compositions for generating human monoclonal antibodies |
| WO2001057084A1 (en) | 2000-01-31 | 2001-08-09 | Novo Nordisk A/S | Crystallisation of a glp-1 analogue |
| US6844321B2 (en) | 2000-01-31 | 2005-01-18 | Novo Nordisk A/S | Crystallization of a GLP-1 analogue |
| BR0111562A (pt) | 2000-06-16 | 2003-04-15 | Lilly Co Eli | Análogos de peptìdeo 1 semelhantes ao glucagon |
| US7238670B2 (en) | 2001-10-18 | 2007-07-03 | Bristol-Myers Squibb Company | Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions |
| US7179788B2 (en) | 2001-10-19 | 2007-02-20 | Eli Lilly And Company | Biphasic mixtures of GLP-1 and insulin |
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- 2004-12-16 US US11/015,615 patent/US7521527B2/en not_active Expired - Fee Related
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- 2004-12-16 AR ARP040104697A patent/AR047776A1/es not_active Application Discontinuation
- 2004-12-16 JP JP2006545462A patent/JP2007514752A/ja not_active Ceased
- 2004-12-16 WO PCT/US2004/042389 patent/WO2005058252A2/en not_active Ceased
-
2010
- 2010-10-01 JP JP2010224218A patent/JP2011001381A/ja active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2003192698A (ja) * | 1990-01-24 | 2003-07-09 | Douglas I Buckley | 糖尿病治療に有用なｇｌｐ−１アナログ |
| JP2002531578A (ja) * | 1998-12-07 | 2002-09-24 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | Ｇｌｐ−１の類似体 |
| JP2002538081A (ja) * | 1998-12-07 | 2002-11-12 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | Ｇｌｐ−１の類似体 |
| JP2002534450A (ja) * | 1999-01-14 | 2002-10-15 | アミリン・ファーマシューティカルズ，インコーポレイテッド | 新規なエキセンジンアゴニスト製剤とその投与方法 |
| WO2002098348A2 (en) * | 2001-06-01 | 2002-12-12 | Eli Lilly And Company | Glp-1 formulations with protracted time action |
| WO2003002136A2 (en) * | 2001-06-28 | 2003-01-09 | Novo Nordisk A/S | Stable formulation of modified glp-1 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011520879A (ja) * | 2008-05-14 | 2011-07-21 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | ソマトスタチン−ドーパミンコンジュゲートの医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2550695A1 (en) | 2005-06-30 |
| US7521527B2 (en) | 2009-04-21 |
| JP2011001381A (ja) | 2011-01-06 |
| WO2005058252A3 (en) | 2006-08-31 |
| EP1694278A4 (en) | 2009-08-12 |
| EP1694278A2 (en) | 2006-08-30 |
| US20050159356A1 (en) | 2005-07-21 |
| TW200520770A (en) | 2005-07-01 |
| TWI353250B (en) | 2011-12-01 |
| WO2005058252A2 (en) | 2005-06-30 |
| AR047776A1 (es) | 2006-02-22 |
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