JP2007511500A5 - - Google Patents
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- Publication number
- JP2007511500A5 JP2007511500A5 JP2006538977A JP2006538977A JP2007511500A5 JP 2007511500 A5 JP2007511500 A5 JP 2007511500A5 JP 2006538977 A JP2006538977 A JP 2006538977A JP 2006538977 A JP2006538977 A JP 2006538977A JP 2007511500 A5 JP2007511500 A5 JP 2007511500A5
- Authority
- JP
- Japan
- Prior art keywords
- solid amorphous
- compound
- dispersion
- weight
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000006185 dispersion Substances 0.000 claims 19
- 239000007787 solid Substances 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 9
- 229920000642 polymer Polymers 0.000 claims 5
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 3
- 229920000639 hydroxypropylmethylcellulose acetate succinate Polymers 0.000 claims 3
- 229920000623 Cellulose acetate phthalate Polymers 0.000 claims 2
- 229940081734 cellulose acetate phthalate Drugs 0.000 claims 2
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 2
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 2
- 229920002301 cellulose acetate Polymers 0.000 claims 1
- WZNRVWBKYDHTKI-UHFFFAOYSA-N cellulose, acetate 1,2,4-benzenetricarboxylate Chemical compound OC1C(O)C(O)C(CO)OC1OC1C(CO)OC(O)C(O)C1O.OC1C(O)C(O)C(CO)OC1OC1C(CO)OC(O)C(O)C1O.CC(=O)OCC1OC(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(COC(C)=O)O1.CC(=O)OCC1OC(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(COC(C)=O)O1.OC(=O)C1=CC(C(=O)O)=CC=C1C(=O)OCC1C(OC2C(C(OC(=O)C=3C(=CC(=CC=3)C(O)=O)C(O)=O)C(OC(=O)C=3C(=CC(=CC=3)C(O)=O)C(O)=O)C(COC(=O)C=3C(=CC(=CC=3)C(O)=O)C(O)=O)O2)OC(=O)C=2C(=CC(=CC=2)C(O)=O)C(O)=O)C(OC(=O)C=2C(=CC(=CC=2)C(O)=O)C(O)=O)C(OC(=O)C=2C(=CC(=CC=2)C(O)=O)C(O)=O)C(OC(=O)C=2C(=CC(=CC=2)C(O)=O)C(O)=O)O1 WZNRVWBKYDHTKI-UHFFFAOYSA-N 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 125000005591 trimellitate group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51993103P | 2003-11-14 | 2003-11-14 | |
| PCT/IB2004/003581 WO2005046644A1 (en) | 2003-11-14 | 2004-11-01 | Solid amorphous dispersions of an mtp inhibitor for treatment of obesity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007511500A JP2007511500A (ja) | 2007-05-10 |
| JP2007511500A5 true JP2007511500A5 (https=) | 2007-12-20 |
Family
ID=34590458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538977A Abandoned JP2007511500A (ja) | 2003-11-14 | 2004-11-01 | 肥満治療のためのｍｔｐ阻害剤の固体非晶性分散体 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20080293801A1 (https=) |
| EP (1) | EP1696887A1 (https=) |
| JP (1) | JP2007511500A (https=) |
| KR (1) | KR20060096076A (https=) |
| CN (1) | CN1878538A (https=) |
| AR (1) | AR048206A1 (https=) |
| AU (1) | AU2004289110A1 (https=) |
| BR (1) | BRPI0416596A (https=) |
| CA (1) | CA2545443A1 (https=) |
| CO (1) | CO5690536A2 (https=) |
| IL (1) | IL175372A0 (https=) |
| MX (1) | MXPA06005489A (https=) |
| NO (1) | NO20062778L (https=) |
| NZ (1) | NZ546677A (https=) |
| TW (1) | TW200515909A (https=) |
| WO (1) | WO2005046644A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE449776T1 (de) | 2005-12-15 | 2009-12-15 | Hoffmann La Roche | Pyrroloä2,3-cüpyridinderivate |
| WO2008090198A1 (en) * | 2007-01-25 | 2008-07-31 | Janssen Pharmaceutica Nv | Use of mtp inhibitors for increasing levels of satiety hormones |
| CN102781914B (zh) * | 2010-01-06 | 2014-09-17 | 武田药品工业株式会社 | 吲哚衍生物 |
| US8313774B1 (en) | 2012-06-26 | 2012-11-20 | Magnifica Inc. | Oral solid composition |
| EP3861989A1 (en) * | 2020-02-07 | 2021-08-11 | Bayer Aktiengesellschaft | Pharmaceutical composition containing regorafenib and a stabilizing agent |
| US12453728B1 (en) | 2024-08-08 | 2025-10-28 | Redux Therapeutics, Llc | Compositions comprising inhibitors of microsomal triglyceride transfer protein and Apo-B secretion |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
| US4884235A (en) * | 1988-07-19 | 1989-11-28 | Thiele Alfred A | Micromagnetic memory package |
| KR0182801B1 (ko) * | 1991-04-16 | 1999-05-01 | 아만 히데아키 | 고체 분산체의 제조방법 |
| US5340591A (en) * | 1992-01-24 | 1994-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine |
| JP3265680B2 (ja) * | 1992-03-12 | 2002-03-11 | 大正製薬株式会社 | 経口製剤用組成物 |
| DE19504832A1 (de) * | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
| ATE364374T1 (de) * | 1997-08-11 | 2007-07-15 | Pfizer Prod Inc | Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit |
| SK287806B6 (sk) * | 2001-06-28 | 2011-10-04 | Pfizer Products Inc. | Triamid-substituované indoly, benzofurány a benzotiofény ako inhibítory mikrozómového proteínu prenášajúceho triglyceridu (MTP) a/alebo sekrécie apolipoproteínu B (Apo B) |
| AR038375A1 (es) * | 2002-02-01 | 2005-01-12 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo |
-
2004
- 2004-11-01 WO PCT/IB2004/003581 patent/WO2005046644A1/en not_active Ceased
- 2004-11-01 EP EP04798760A patent/EP1696887A1/en not_active Withdrawn
- 2004-11-01 KR KR1020067009334A patent/KR20060096076A/ko not_active Ceased
- 2004-11-01 BR BRPI0416596-9A patent/BRPI0416596A/pt not_active IP Right Cessation
- 2004-11-01 NZ NZ546677A patent/NZ546677A/en unknown
- 2004-11-01 CA CA002545443A patent/CA2545443A1/en not_active Abandoned
- 2004-11-01 JP JP2006538977A patent/JP2007511500A/ja not_active Abandoned
- 2004-11-01 CN CNA2004800334168A patent/CN1878538A/zh active Pending
- 2004-11-01 US US10/595,732 patent/US20080293801A1/en not_active Abandoned
- 2004-11-01 MX MXPA06005489A patent/MXPA06005489A/es unknown
- 2004-11-01 AU AU2004289110A patent/AU2004289110A1/en not_active Abandoned
- 2004-11-12 TW TW093134701A patent/TW200515909A/zh unknown
- 2004-11-12 AR ARP040104185A patent/AR048206A1/es unknown
-
2006
- 2006-05-01 IL IL175372A patent/IL175372A0/en unknown
- 2006-05-12 CO CO06045059A patent/CO5690536A2/es unknown
- 2006-06-14 NO NO20062778A patent/NO20062778L/no not_active Application Discontinuation
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