JP2007509647A - 液状薬剤送達用マイクロポンプ - Google Patents
液状薬剤送達用マイクロポンプ Download PDFInfo
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- JP2007509647A JP2007509647A JP2006536198A JP2006536198A JP2007509647A JP 2007509647 A JP2007509647 A JP 2007509647A JP 2006536198 A JP2006536198 A JP 2006536198A JP 2006536198 A JP2006536198 A JP 2006536198A JP 2007509647 A JP2007509647 A JP 2007509647A
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- 239000007788 liquid Substances 0.000 title claims abstract description 55
- 238000012377 drug delivery Methods 0.000 title description 2
- 239000003814 drug Substances 0.000 claims abstract description 10
- 238000004891 communication Methods 0.000 claims description 20
- 230000006698 induction Effects 0.000 claims description 4
- 239000004033 plastic Substances 0.000 claims description 4
- 229920003023 plastic Polymers 0.000 claims description 4
- 239000012530 fluid Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 238000001746 injection moulding Methods 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 abstract description 5
- 238000007789 sealing Methods 0.000 abstract description 3
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 46
- 102000004877 Insulin Human genes 0.000 description 23
- 108090001061 Insulin Proteins 0.000 description 23
- 229940125396 insulin Drugs 0.000 description 23
- 230000006870 function Effects 0.000 description 12
- 238000006073 displacement reaction Methods 0.000 description 9
- 238000002347 injection Methods 0.000 description 7
- 239000007924 injection Substances 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 230000005355 Hall effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
- F04B19/006—Micropumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B7/00—Piston machines or pumps characterised by having positively-driven valving
- F04B7/04—Piston machines or pumps characterised by having positively-driven valving in which the valving is performed by pistons and cylinders coacting to open and close intake or outlet ports
- F04B7/06—Piston machines or pumps characterised by having positively-driven valving in which the valving is performed by pistons and cylinders coacting to open and close intake or outlet ports the pistons and cylinders being relatively reciprocated and rotated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6054—Magnetic identification systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/01—Remote controllers for specific apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16877—Adjusting flow; Devices for setting a flow rate
- A61M5/16881—Regulating valves
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- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Reciprocating Pumps (AREA)
- Compressors, Vaccum Pumps And Other Relevant Systems (AREA)
- External Artificial Organs (AREA)
- Details Of Reciprocating Pumps (AREA)
Abstract
【選択図】図3C
Description
ΔV=V2−V1
が患者へ流れるのを引き起こす。
F=2π(1/2+1/π ArcSin[(2a+B)/D])
一つの実施例として、本発明によって作製されたインスリンポンプについての上記の寸法の数値は、ほぼ以下の通りであろう:
ポンプモジュールステーターの全外径 ≒9mm
ローター径 ≒6mm
ローターの幅 ≒2mm
ΔV=10−50.10−9l(ナノリットル)
パラメーターB、Dおよびaについての典型的な数値は、例えば以下のとおりであろう:
B ≒5〜20μ
D ≒0.2〜0.5mm
a ≒0.1〜0.2mm
第一軸方向伸長部の直径D1 ≒ 0.6mm
第二軸方向伸長部の直径D2 ≒ 0.4mm
この場合には、ΔV ≒ 10.10−9l(ナノリットル)である。
Claims (18)
- 液状薬剤を皮下送達するためのポンプシステムであって、
チャンバー(30)を備えるステーターハウジング(28)と、
チャンバー内で回転可能かつ軸方向へスライド可能に受け入れられており、第一軸方向伸長部(46)および第二軸方向伸長部(48)を含むローターであって、前記第一および第二軸方向伸長部が相違する径を有するローター(32)と、ならびに
前記第一および第二軸方向伸長部の周囲に取り付けられた第一および第二シールリング(54、56)と、を含むポンプモジュール(10)を有するポンプシステム。 - 前記第一および第二軸方向伸長部が液体供給通路を含む、請求項1に記載のポンプシステム。
- 前記第一および第二シールリング(54、56)が、前記ローターの回転軸に対して垂直な平面に対して傾斜角φ1、φ2で取り付けられている、先行請求項に記載のポンプシステム。
- 前記シールリングがOリングシールである、請求項2または3に記載のポンプシステム。
- 前記液体供給通路(50)が前記軸方向伸長部の表面上で軸方向に伸びる溝の形状にある、請求項2から4のいずれか一項に記載のポンプシステム。
- 前記軸方向伸長部が前記ローターの本体の反対側から伸びている、先行請求項のいずれか一項に記載のポンプシステム。
- 前記ローターが前記ローターの本体の半径方向周辺の近くへ取り付けられた一つ以上の永久磁石を含む、先行請求項のいずれか一項に記載のポンプシステム。
- ステーター部分に取り付けられていて、ステップモーターとして機能するために前記ローター内に取り付けられた一つ以上の永久磁石に作用する磁気誘導コイル(18)をさらに含む、先行請求項のいずれか一項に記載のポンプシステム。
- 前記ローターの軸方向位置を検出するためにステーター部分に取り付けられた位置センサー(66)および前記ローターの軸方向位置を検出するための位置センサー(64)をさらに含む、先行請求項のいずれか一項に記載のポンプシステム。
- 供給量の前記液状薬剤を含有するリザーバー(8)をさらに含み、前記ポンプモジュールが前記リザーバーへ組み立てられていて前記リザーバーの内側と液体連絡している入口(42)を有する、先行請求項のいずれか一項に記載のポンプシステム。
- 前記ポンプモジュールが前記リザーバー上に取り付けられていて、それと一緒に使い捨て液体供給ユニット(6)を形成する、先行請求項のいずれか一項に記載のポンプシステム。
- 前記ローターを駆動させるために磁気誘導コイルに接続された電子制御・通信モジュール(20)をさらに含む、先行請求項のいずれか一項に記載のポンプシステム。
- 前記電子制御・通信モジュールが、ユーザー用のディスプレイ・コントロールユニットと無線通信するためのRFトランシーバーを含む、先行請求項のいずれか一項に記載のポンプシステム。
- 前記ローターが、主として射出成型用プラスチック材料から製造される、先行請求項のいずれか一項に記載のポンプシステム。
- 磁石が、前記ローターの本体部分にオーバーモールドするステップによって埋め込まれる、先行請求項のいずれか一項に記載のポンプシステム。
- 前記ステーターハウジングが、主として射出成型用プラスチック材料から製造される、先行請求項のいずれか一項に記載のポンプシステム。
- 前記ポンプモジュールが、ポンピングされる液体の量の関数としての前記ローター回転数と関連付けたポンプモジュールの校正に関する情報を保存するRFIDトランスポンダー(23)を含む、先行請求項のいずれか一項に記載のポンプシステム。
- 前記電子制御・通信モジュールが、前記ポンプモジュール(10)を含む使い捨て液体供給ユニット(6)へ取り付けられたRFIDトランスポンダー(23)と無線通信するためのRFIDリーダー(21)を含む、請求項12または13に記載のポンプシステム。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03024653A EP1527793A1 (en) | 2003-10-27 | 2003-10-27 | Liquid drug delivery micropump |
PCT/IB2004/003385 WO2005039674A1 (en) | 2003-10-27 | 2004-10-15 | Liquid drug delivery micropump |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007509647A true JP2007509647A (ja) | 2007-04-19 |
JP4609775B2 JP4609775B2 (ja) | 2011-01-12 |
Family
ID=34400470
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006536198A Active JP4609775B2 (ja) | 2003-10-27 | 2004-10-15 | 液状薬剤送達用マイクロポンプ |
Country Status (12)
Country | Link |
---|---|
US (1) | US7726955B2 (ja) |
EP (2) | EP1527793A1 (ja) |
JP (1) | JP4609775B2 (ja) |
KR (1) | KR101129404B1 (ja) |
CN (1) | CN100448492C (ja) |
AT (1) | ATE458514T1 (ja) |
CA (1) | CA2541121C (ja) |
DE (1) | DE602004025720D1 (ja) |
DK (1) | DK1677859T3 (ja) |
ES (1) | ES2341862T3 (ja) |
PL (1) | PL1677859T3 (ja) |
WO (1) | WO2005039674A1 (ja) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010535569A (ja) * | 2007-08-07 | 2010-11-25 | ゼンズィーレ パット アーゲー | 不連続用量の薬剤を投与するためのモジュラー型薬品送達デバイス |
JP2016026558A (ja) * | 2014-07-02 | 2016-02-18 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 内部カム計量ポンプ |
JP2018518320A (ja) * | 2015-06-22 | 2018-07-12 | メドトロニック ミニメド インコーポレイテッド | 回転ポンプ機構を有する輸液装置用閉塞検出技術 |
KR20200101361A (ko) * | 2017-12-20 | 2020-08-27 | 젠질레 메디칼 아게 | 마이크로 펌프 |
JP2022088369A (ja) * | 2017-12-12 | 2022-06-14 | ゼンジーレ・メディカル・アーゲー | ロータの軸方向変位のためのカム機構を備えるマイクロポンプ |
Families Citing this family (49)
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US7955305B2 (en) * | 2005-05-06 | 2011-06-07 | Medtronic Minimed, Inc. | Needle inserter and method for infusion device |
DK1803934T3 (da) * | 2005-12-28 | 2009-02-02 | Sensile Pat Ag | Mikropumpe |
AU2011232741B2 (en) * | 2005-12-28 | 2012-12-20 | Sensile Medical Ag | Micropump |
DE102005063196A1 (de) * | 2005-12-30 | 2007-07-05 | Braun Gmbh | Applikationsstoffbehälter für Zahnbürsten und elektrische Zahnbürste |
EP1839695A1 (en) | 2006-03-31 | 2007-10-03 | Debiotech S.A. | Medical liquid injection device |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
CA2737461A1 (en) | 2008-09-19 | 2010-03-25 | Tandem Diabetes Care, Inc. | Solute concentration measurement device and related methods |
FR2936160B1 (fr) * | 2008-09-22 | 2010-09-10 | Bernard Perriere | Dispositif d'injection avec micropompe electrique a helice |
BRPI0919583A2 (pt) | 2008-10-01 | 2015-12-08 | H R D Corp | sistema para aplicar tensão de cisalhamento ex-situ a um fluido, e, métodos para preparar um fluido para administração intravenosa a um paciente, e para realizar terapia celular em um paciente. |
EP2401587A2 (en) | 2009-02-27 | 2012-01-04 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
US9250106B2 (en) | 2009-02-27 | 2016-02-02 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
EP2275678B1 (en) * | 2009-07-13 | 2019-03-06 | Sensile Medical AG | Pump with rotor position measurement system |
US8926561B2 (en) | 2009-07-30 | 2015-01-06 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
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US9222470B2 (en) | 2010-03-17 | 2015-12-29 | Sensile Pat Ag | Micropump |
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US8905972B2 (en) | 2010-11-20 | 2014-12-09 | Perqflo, Llc | Infusion pumps |
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WO2013005159A1 (en) | 2011-07-06 | 2013-01-10 | Sensile Pat Ag | Liquid dispensing system |
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US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
DK2764881T3 (da) | 2013-02-06 | 2019-10-28 | Medirio Sa | System til medicinsk behandling |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
EP2832390A1 (en) | 2013-07-30 | 2015-02-04 | Sensile Pat AG | Drug delivery device with needle actuation mechanism |
US9565718B2 (en) | 2013-09-10 | 2017-02-07 | Tandem Diabetes Care, Inc. | System and method for detecting and transmitting medical device alarm with a smartphone application |
US10184461B2 (en) | 2013-09-18 | 2019-01-22 | Smiths Medical Asd, Inc. | Pump device and method therefor of conveying fluid, and method of manufacturing the pump device |
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US10004845B2 (en) | 2014-04-18 | 2018-06-26 | Becton, Dickinson And Company | Split piston metering pump |
US10159786B2 (en) | 2014-09-30 | 2018-12-25 | Perqflo, Llc | Hybrid ambulatory infusion pumps |
EP3258989B1 (en) | 2015-02-18 | 2020-01-01 | Medtronic Minimed, Inc. | Ambulatory infusion pump with static and dynamic seals |
WO2017135936A1 (en) * | 2016-02-02 | 2017-08-10 | Perqflo, Llc | Hybrid ambulatory infusion pump with contactless power transmission |
US10940264B2 (en) | 2016-02-12 | 2021-03-09 | Medtronic Minimed, Inc. | Ambulatory infusion pumps and assemblies for use with same |
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- 2004-10-15 US US10/576,780 patent/US7726955B2/en active Active
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- 2004-10-15 JP JP2006536198A patent/JP4609775B2/ja active Active
- 2004-10-15 CN CNB2004800308036A patent/CN100448492C/zh active Active
- 2004-10-15 WO PCT/IB2004/003385 patent/WO2005039674A1/en active Application Filing
- 2004-10-15 PL PL04769652T patent/PL1677859T3/pl unknown
- 2004-10-15 EP EP04769652A patent/EP1677859B9/en active Active
- 2004-10-15 DE DE602004025720T patent/DE602004025720D1/de active Active
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JP2010535569A (ja) * | 2007-08-07 | 2010-11-25 | ゼンズィーレ パット アーゲー | 不連続用量の薬剤を投与するためのモジュラー型薬品送達デバイス |
JP2016026558A (ja) * | 2014-07-02 | 2016-02-18 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 内部カム計量ポンプ |
JP2018518320A (ja) * | 2015-06-22 | 2018-07-12 | メドトロニック ミニメド インコーポレイテッド | 回転ポンプ機構を有する輸液装置用閉塞検出技術 |
JP2022088369A (ja) * | 2017-12-12 | 2022-06-14 | ゼンジーレ・メディカル・アーゲー | ロータの軸方向変位のためのカム機構を備えるマイクロポンプ |
JP7379559B2 (ja) | 2017-12-12 | 2023-11-14 | ゼンジーレ・メディカル・アーゲー | ロータの軸方向変位のためのカム機構を備えるマイクロポンプ |
KR20200101361A (ko) * | 2017-12-20 | 2020-08-27 | 젠질레 메디칼 아게 | 마이크로 펌프 |
JP2021506522A (ja) * | 2017-12-20 | 2021-02-22 | ゼンジーレ・メディカル・アーゲー | マイクロポンプ |
KR102382938B1 (ko) | 2017-12-20 | 2022-04-04 | 젠질레 메디칼 아게 | 마이크로 펌프 |
JP7047100B2 (ja) | 2017-12-20 | 2022-04-04 | ゼンジーレ・メディカル・アーゲー | マイクロポンプ |
Also Published As
Publication number | Publication date |
---|---|
CN100448492C (zh) | 2009-01-07 |
KR20060110869A (ko) | 2006-10-25 |
CN1871040A (zh) | 2006-11-29 |
ATE458514T1 (de) | 2010-03-15 |
EP1677859A1 (en) | 2006-07-12 |
US20070071596A1 (en) | 2007-03-29 |
ES2341862T3 (es) | 2010-06-29 |
WO2005039674A1 (en) | 2005-05-06 |
DK1677859T3 (da) | 2010-06-14 |
US7726955B2 (en) | 2010-06-01 |
PL1677859T3 (pl) | 2010-11-30 |
EP1677859B9 (en) | 2010-09-01 |
CA2541121C (en) | 2012-04-17 |
DE602004025720D1 (de) | 2010-04-08 |
KR101129404B1 (ko) | 2012-03-27 |
JP4609775B2 (ja) | 2011-01-12 |
EP1677859B1 (en) | 2010-02-24 |
EP1527793A1 (en) | 2005-05-04 |
CA2541121A1 (en) | 2005-05-06 |
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