JP2007506803A5 - - Google Patents

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Publication number
JP2007506803A5
JP2007506803A5 JP2006533446A JP2006533446A JP2007506803A5 JP 2007506803 A5 JP2007506803 A5 JP 2007506803A5 JP 2006533446 A JP2006533446 A JP 2006533446A JP 2006533446 A JP2006533446 A JP 2006533446A JP 2007506803 A5 JP2007506803 A5 JP 2007506803A5
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JP
Japan
Prior art keywords
aliphatic
aryl
heteroaryl
heterocyclyl
cycloaliphatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006533446A
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English (en)
Japanese (ja)
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JP2007506803A (ja
JP4791365B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/016706 external-priority patent/WO2004106304A2/en
Publication of JP2007506803A publication Critical patent/JP2007506803A/ja
Publication of JP2007506803A5 publication Critical patent/JP2007506803A5/ja
Application granted granted Critical
Publication of JP4791365B2 publication Critical patent/JP4791365B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2006533446A 2003-05-27 2004-05-27 カスパーゼ阻害剤およびそれらの用途 Expired - Fee Related JP4791365B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47362203P 2003-05-27 2003-05-27
US60/473,622 2003-05-27
PCT/US2004/016706 WO2004106304A2 (en) 2003-05-27 2004-05-27 3 - [2- (3-amino-2-oxo-2h-pyridin-1-yl) - acetylamino] - 4- oxo-pentanoic acid derivatives and their use as caspase inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007139751A Division JP2007308501A (ja) 2003-05-27 2007-05-25 カスパーゼ阻害剤およびそれらの用途

Publications (3)

Publication Number Publication Date
JP2007506803A JP2007506803A (ja) 2007-03-22
JP2007506803A5 true JP2007506803A5 (enExample) 2007-07-19
JP4791365B2 JP4791365B2 (ja) 2011-10-12

Family

ID=33490622

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2006533446A Expired - Fee Related JP4791365B2 (ja) 2003-05-27 2004-05-27 カスパーゼ阻害剤およびそれらの用途
JP2007139751A Pending JP2007308501A (ja) 2003-05-27 2007-05-25 カスパーゼ阻害剤およびそれらの用途
JP2011215594A Pending JP2012021019A (ja) 2003-05-27 2011-09-29 カスパーゼ阻害剤およびそれらの用途
JP2011215595A Pending JP2012036206A (ja) 2003-05-27 2011-09-29 カスパーゼ阻害剤およびそれらの用途

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2007139751A Pending JP2007308501A (ja) 2003-05-27 2007-05-25 カスパーゼ阻害剤およびそれらの用途
JP2011215594A Pending JP2012021019A (ja) 2003-05-27 2011-09-29 カスパーゼ阻害剤およびそれらの用途
JP2011215595A Pending JP2012036206A (ja) 2003-05-27 2011-09-29 カスパーゼ阻害剤およびそれらの用途

Country Status (19)

Country Link
US (2) US20040242494A1 (enExample)
EP (2) EP2412707A3 (enExample)
JP (4) JP4791365B2 (enExample)
KR (2) KR20110114735A (enExample)
CN (2) CN101775012A (enExample)
AR (1) AR044770A1 (enExample)
AU (1) AU2004243308B9 (enExample)
BR (1) BRPI0410669A (enExample)
CA (1) CA2526749A1 (enExample)
IL (1) IL172159A (enExample)
MX (1) MXPA05012837A (enExample)
NO (1) NO20056192L (enExample)
NZ (2) NZ544156A (enExample)
PE (1) PE20050159A1 (enExample)
RU (1) RU2372335C2 (enExample)
TW (2) TWI344956B (enExample)
UY (1) UY28333A1 (enExample)
WO (1) WO2004106304A2 (enExample)
ZA (1) ZA200509700B (enExample)

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JP5102834B2 (ja) * 2006-08-02 2012-12-19 エルジー・ライフ・サイエンシーズ・リミテッド ピリダジノン構造を含むカスパーゼ阻害剤
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WO2010120880A1 (en) * 2009-04-14 2010-10-21 Vertex Pharmaceuticals Incorporated Treatment of liver diseases with a caspase inhibitor
US9956260B1 (en) 2011-07-22 2018-05-01 The J. David Gladstone Institutes Treatment of HIV-1 infection and AIDS
US9650360B2 (en) * 2012-03-31 2017-05-16 University Of Georgia Research Foundation, Inc. Anti-mycobacterial drugs against tuberculosis
EP2687511A1 (de) * 2012-07-17 2014-01-22 Zedira GmbH Pyridinonderivate als Gewebetransglutaminaseinhibitoren
US9969283B2 (en) 2013-09-10 2018-05-15 General Electric Company Battery changing system and method
US10143267B1 (en) 2013-12-31 2018-12-04 Dynasty Footwear, Ltd. Shoe bottom surface having attached particles
EP3444011A1 (en) 2014-05-12 2019-02-20 Conatus Pharmaceuticals, Inc. Treatment of the complications of chronic liver disease with emricasan
WO2017079566A1 (en) 2015-11-05 2017-05-11 Conatus Pharmaceuticals, Inc. Caspase inhibitors for use in the treatment of liver cancer
KR20180101418A (ko) 2015-12-31 2018-09-12 코나터스 파마슈티칼스, 인크. 간 질환의 치료에서의 카스파제 억제제의 사용 방법
MX2019003889A (es) 2016-10-05 2019-08-12 Novartis Ag Composiciones de combinacion que comprenden agonistas de fxr para tratar o prevenir una enfermedad o trastorno fibrotico o cirrotico.
WO2019231739A1 (en) 2018-05-29 2019-12-05 Cersci Therapeutics, Inc. Compounds for pain treatment, compositions comprising same, and methods of using same
WO2020006341A1 (en) 2018-06-29 2020-01-02 Conatus Pharmaceuticals, Inc. (s)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid derivatives and related compounds as caspase inhibitors for treating cardiovascular diseases
WO2020231496A1 (en) 2019-05-10 2020-11-19 Cersci Therapeutics, Inc. Manufacturing methods and polymorphs of a thiazoline anti-hyperalgesic agent
WO2022123062A1 (en) 2020-12-11 2022-06-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Blocking caspase and/or fasl for preventing fatal outcome in covid-19 patients
KR102670554B1 (ko) * 2022-01-04 2024-05-30 주식회사 이노보테라퓨틱스 캐스파제 저해제로서의 신규한 이소인돌리논 유도체 화합물
WO2025113519A1 (zh) * 2023-11-28 2025-06-05 成都地奥制药集团有限公司 内酰胺环类化合物及其用途

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