JP2007506679A5 - - Google Patents
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- Publication number
- JP2007506679A5 JP2007506679A5 JP2006527053A JP2006527053A JP2007506679A5 JP 2007506679 A5 JP2007506679 A5 JP 2007506679A5 JP 2006527053 A JP2006527053 A JP 2006527053A JP 2006527053 A JP2006527053 A JP 2006527053A JP 2007506679 A5 JP2007506679 A5 JP 2007506679A5
- Authority
- JP
- Japan
- Prior art keywords
- methoxy
- methyl
- group
- oxo
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50521503P | 2003-09-23 | 2003-09-23 | |
| US60/505,215 | 2003-09-23 | ||
| PCT/US2004/030484 WO2005030726A1 (en) | 2003-09-23 | 2004-09-17 | Isoquinolinone potassium channel inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007506679A JP2007506679A (ja) | 2007-03-22 |
| JP2007506679A5 true JP2007506679A5 (https=) | 2007-10-25 |
| JP4717815B2 JP4717815B2 (ja) | 2011-07-06 |
Family
ID=34392991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006527053A Expired - Fee Related JP4717815B2 (ja) | 2003-09-23 | 2004-09-17 | イソキノリノンカリウムチャネル阻害剤 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7741322B2 (https=) |
| EP (1) | EP1667976B1 (https=) |
| JP (1) | JP4717815B2 (https=) |
| CN (1) | CN1856472A (https=) |
| AT (1) | ATE476419T1 (https=) |
| AU (1) | AU2004276238B2 (https=) |
| CA (1) | CA2539729C (https=) |
| DE (1) | DE602004028493D1 (https=) |
| WO (1) | WO2005030726A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4719151B2 (ja) * | 2003-09-23 | 2011-07-06 | メルク・シャープ・エンド・ドーム・コーポレイション | イソキノリノンカリウムチャネル阻害剤 |
| WO2005030791A2 (en) * | 2003-09-23 | 2005-04-07 | Merck & Co., Inc. | Isoquinolinone potassium channel inhibitors |
| CN1856473A (zh) * | 2003-09-23 | 2006-11-01 | 默克公司 | 异喹啉酮钾通道抑制剂 |
| EP1667981A4 (en) * | 2003-09-23 | 2008-08-13 | Merck & Co Inc | ISOCHINOLINE AS KALIUM CHANNEL INHIBITORS |
| US7879839B2 (en) | 2004-07-29 | 2011-02-01 | Merck Sharp & Dohme Corp. | Potassium channel inhibitors |
| US7569589B2 (en) | 2004-07-29 | 2009-08-04 | Merck & Co., Inc. | Potassium channel inhibitors |
| EP1922311A2 (en) | 2005-09-09 | 2008-05-21 | Brystol-Myers Squibb Company | Acyclic ikur inhibitors |
| EP1996198A1 (en) * | 2006-03-17 | 2008-12-03 | Kalypsys, Inc. | Alkylamine-substituted bicyclic aryl compounds useful as modulators of ppar |
| DE102006019589A1 (de) * | 2006-04-27 | 2007-10-31 | Sanofi-Aventis Deutschland Gmbh | Inhibitoren des TASK-1 und Task-3 Ionenkanals |
| US9623021B2 (en) * | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
| US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
| ES2475193T3 (es) | 2007-01-22 | 2014-07-10 | Gtx, Inc. | Agentes de unión al receptor nuclear |
| EP3668841A1 (en) * | 2017-08-14 | 2020-06-24 | Acesion Pharma ApS | Substituted benzimidazoles as potassium channel inhibitors |
| CN110670090B (zh) * | 2019-11-13 | 2021-06-29 | 广西师范大学 | 一种基于电化学合成异喹啉酮类化合物的方法 |
| KR20240149429A (ko) * | 2022-02-16 | 2024-10-14 | 듀크 스트리트 바이오 리미티드 | 약학적 화합물 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3594380A (en) * | 1969-02-18 | 1971-07-20 | American Home Prod | Isoquinolin-1(2h)-ones |
| EP0585913B1 (en) | 1992-09-04 | 1997-12-29 | Takeda Chemical Industries, Ltd. | Condensed heterocyclic compounds, their production and use |
| EP0634402A1 (en) * | 1993-07-14 | 1995-01-18 | Takeda Chemical Industries, Ltd. | Isochinolinone derivatives, their production and use |
| US5387685A (en) | 1993-07-16 | 1995-02-07 | American Cyanamid Co | MDR reversal agents |
| EP1322619B1 (en) | 2000-09-20 | 2008-01-23 | Merck & Co., Inc. | Isoquinolinone potassium channel inhibitors |
| JPWO2002094790A1 (ja) * | 2001-05-23 | 2004-09-09 | 三菱ウェルファーマ株式会社 | 縮合ヘテロ環化合物およびその医薬用途 |
| AU2003211931A1 (en) * | 2002-02-13 | 2003-09-04 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
| JP4719151B2 (ja) * | 2003-09-23 | 2011-07-06 | メルク・シャープ・エンド・ドーム・コーポレイション | イソキノリノンカリウムチャネル阻害剤 |
| WO2005030791A2 (en) * | 2003-09-23 | 2005-04-07 | Merck & Co., Inc. | Isoquinolinone potassium channel inhibitors |
| CN1856473A (zh) * | 2003-09-23 | 2006-11-01 | 默克公司 | 异喹啉酮钾通道抑制剂 |
| EP1667981A4 (en) * | 2003-09-23 | 2008-08-13 | Merck & Co Inc | ISOCHINOLINE AS KALIUM CHANNEL INHIBITORS |
-
2004
- 2004-09-17 WO PCT/US2004/030484 patent/WO2005030726A1/en not_active Ceased
- 2004-09-17 CN CNA2004800273770A patent/CN1856472A/zh active Pending
- 2004-09-17 AT AT04784368T patent/ATE476419T1/de not_active IP Right Cessation
- 2004-09-17 CA CA2539729A patent/CA2539729C/en not_active Expired - Fee Related
- 2004-09-17 DE DE602004028493T patent/DE602004028493D1/de not_active Expired - Lifetime
- 2004-09-17 US US10/571,858 patent/US7741322B2/en not_active Expired - Fee Related
- 2004-09-17 EP EP04784368A patent/EP1667976B1/en not_active Expired - Lifetime
- 2004-09-17 JP JP2006527053A patent/JP4717815B2/ja not_active Expired - Fee Related
- 2004-09-17 AU AU2004276238A patent/AU2004276238B2/en not_active Ceased
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