JP2007504825A5 - - Google Patents

Info

Publication number

JP2007504825A5

JP2007504825A5 JP2006526255A JP2006526255A JP2007504825A5 JP 2007504825 A5 JP2007504825 A5 JP 2007504825A5 JP 2006526255 A JP2006526255 A JP 2006526255A JP 2006526255 A JP2006526255 A JP 2006526255A JP 2007504825 A5 JP2007504825 A5 JP 2007504825A5

Authority

JP

Japan

Prior art keywords

seq

nucleic acid

isolated

isolated peptide

biological sample

Prior art date

2004-09-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 150000007523 nucleic acids Chemical class 0.000 claims 32
• 108090000765 processed proteins & peptides Proteins 0.000 claims 27
• 239000012472 biological sample Substances 0.000 claims 16
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 14
• 108020004707 nucleic acids Proteins 0.000 claims 13
• 102000039446 nucleic acids Human genes 0.000 claims 13
• 206010012601 diabetes mellitus Diseases 0.000 claims 11
• 238000000034 method Methods 0.000 claims 11
• 208000008589 Obesity Diseases 0.000 claims 10
• 235000020824 obesity Nutrition 0.000 claims 10
• 150000001413 amino acids Chemical class 0.000 claims 9
• 125000003275 alpha amino acid group Chemical group 0.000 claims 8
• 108090000623 proteins and genes Proteins 0.000 claims 7
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 5
• 238000009396 hybridization Methods 0.000 claims 5
• 102000004169 proteins and genes Human genes 0.000 claims 5
• 150000001875 compounds Chemical class 0.000 claims 4
• 102000054767 gene variant Human genes 0.000 claims 3
• 108020004705 Codon Proteins 0.000 claims 2
• 230000000295 complement effect Effects 0.000 claims 2
• 239000013604 expression vector Substances 0.000 claims 2
• 239000000463 material Substances 0.000 claims 2
• 239000000523 sample Substances 0.000 claims 2
• 108020000948 Antisense Oligonucleotides Proteins 0.000 claims 1
• 239000002253 acid Substances 0.000 claims 1
• 239000000074 antisense oligonucleotide Substances 0.000 claims 1
• 238000012230 antisense oligonucleotides Methods 0.000 claims 1
• 230000000694 effects Effects 0.000 claims 1
• 108020004999 messenger RNA Proteins 0.000 claims 1
• 239000002773 nucleotide Substances 0.000 claims 1
• 125000003729 nucleotide group Chemical group 0.000 claims 1
• 238000003752 polymerase chain reaction Methods 0.000 claims 1
• 230000004481 post-translational protein modification Effects 0.000 claims 1
• 102000011690 Adiponectin Human genes 0.000 description 1
• 108010076365 Adiponectin Proteins 0.000 description 1