CN101023184A - 用于诊断、监测和治疗肥胖和/或糖尿病的组合物、试剂和试剂盒以及方法 - Google Patents

用于诊断、监测和治疗肥胖和/或糖尿病的组合物、试剂和试剂盒以及方法 Download PDF

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CN101023184A
CN101023184A CNA2004800262032A CN200480026203A CN101023184A CN 101023184 A CN101023184 A CN 101023184A CN A2004800262032 A CNA2004800262032 A CN A2004800262032A CN 200480026203 A CN200480026203 A CN 200480026203A CN 101023184 A CN101023184 A CN 101023184A
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利亚特·明茨
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6879—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for sex determination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01146—11-Beta-hydroxysteroid dehydrogenase (1.1.1.146)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNA2004800262032A 2003-09-11 2004-09-09 用于诊断、监测和治疗肥胖和/或糖尿病的组合物、试剂和试剂盒以及方法 Pending CN101023184A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/659,782 2003-09-11
US10/659,782 US7176292B2 (en) 2003-09-11 2003-09-11 Ghrelin variant protein

Publications (1)

Publication Number Publication Date
CN101023184A true CN101023184A (zh) 2007-08-22

Family

ID=34273528

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800262032A Pending CN101023184A (zh) 2003-09-11 2004-09-09 用于诊断、监测和治疗肥胖和/或糖尿病的组合物、试剂和试剂盒以及方法

Country Status (14)

Country Link
US (2) US7176292B2 (https=)
EP (1) EP1664346B1 (https=)
JP (2) JP2007504825A (https=)
KR (1) KR101081040B1 (https=)
CN (1) CN101023184A (https=)
AT (1) ATE480641T1 (https=)
AU (2) AU2004273053B2 (https=)
BR (1) BRPI0414365A (https=)
CA (1) CA2538514C (https=)
DE (1) DE602004029061D1 (https=)
IL (2) IL174195A (https=)
NZ (1) NZ546488A (https=)
RU (1) RU2420583C2 (https=)
WO (1) WO2005026392A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108138239A (zh) * 2015-07-24 2018-06-08 高丽大学校产学协力团 用于确定衰老、确定肥胖症和诊断癌症的生物标志物和使用其的诊断试剂盒

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8512971B2 (en) * 2002-12-10 2013-08-20 Echelon Biosciences, Inc. Compounds and methods of use thereof for assaying lysophospholipase D activity
US20050208658A1 (en) * 2003-11-21 2005-09-22 The University Of Maryland RNA interference mediated inhibition of 11beta hydroxysteriod dehydrogenase-1 (11beta HSD-1) gene expression
EP1747264B1 (de) 2004-05-21 2012-09-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Multizelluläre gewebe- und organkultursysteme
WO2005119525A1 (en) * 2004-06-04 2005-12-15 Pfizer Products Inc. 11βHSD1 CRYSTAL STRUCTURES FOR STRUCTURE BASED DRUG DESIGN
WO2007055996A2 (en) * 2005-11-03 2007-05-18 Liat Mintz Compositions, reagents and kits for and methods of diagnosing, monitoring and treating hormonal imbalance
NZ571183A (en) * 2006-03-13 2010-09-30 Liat Mintz Use of ghrelin splice variant for treating cachexia and/or anorexia and/or anorexia-cachexia and/or malnutrition and/or lipodystrophy and/or muscle wasting and/or appetite stimulation
US7763707B2 (en) * 2006-03-13 2010-07-27 Liat Mintz Use of ghrelin splice variant for treating cachexia and/or anorexia and/or anorexia-cachexia and/or malnutrition and/or lipodystrophy and/or muscle wasting and/or appetite-stimulation
WO2007126792A2 (en) * 2006-03-28 2007-11-08 Liat Mintz Use of ghrelin splice variant for treating high cholesterol levels or high plasma glucose levels and releated diseases
WO2009048903A1 (en) * 2007-10-08 2009-04-16 Bristol-Myers Squibb Company 11 beta hydroxysteroid dehydrogenase type 1
JP2011516038A (ja) * 2008-03-12 2011-05-26 オタゴ イノベーション リミテッド バイオマーカー
ES2372337B1 (es) * 2010-06-10 2013-01-18 Servicio Andaluz De Salud Variante de la ghrelina y sus usos.
WO2013113916A2 (en) * 2012-02-03 2013-08-08 Zealand Pharma A/S Ghrelin analogues
CN102721819B (zh) * 2012-06-28 2014-08-13 广州瑞博奥生物科技有限公司 一种脂联素的竞争抑制性酶联免疫检测试剂盒及方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291653B1 (en) * 1997-03-24 2001-09-18 Zymogenetics, Inc. Antibodies to motilin homologs
US20040023874A1 (en) * 2002-03-15 2004-02-05 Burgess Catherine E. Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US6967237B2 (en) 2000-05-30 2005-11-22 Merck & Co., Inc. Ghrelin analogs
DK1426764T3 (da) * 2001-08-17 2011-06-27 Fujirebio Kk Fremgangsmåde til diagnosticering eller monitorering af fejl i sukkermetabolisme
EP1458758A2 (en) * 2001-12-21 2004-09-22 Maxygen Aps Adiponectin fragments and conjugates
AU2002364586A1 (en) * 2001-12-21 2003-07-30 Delta Biotechnology Limited Albumin fusion proteins
WO2003059934A2 (en) * 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin fusion proteins
CA2473781A1 (en) * 2002-01-18 2003-07-31 Protemix Corporation Limited Glycoisoforms of adiponectin and uses thereof
JPWO2003063894A1 (ja) * 2002-01-31 2005-05-26 独立行政法人科学技術振興機構 インスリン抵抗性改善剤
NZ571183A (en) * 2006-03-13 2010-09-30 Liat Mintz Use of ghrelin splice variant for treating cachexia and/or anorexia and/or anorexia-cachexia and/or malnutrition and/or lipodystrophy and/or muscle wasting and/or appetite stimulation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108138239A (zh) * 2015-07-24 2018-06-08 高丽大学校产学协力团 用于确定衰老、确定肥胖症和诊断癌症的生物标志物和使用其的诊断试剂盒

Also Published As

Publication number Publication date
WO2005026392A2 (en) 2005-03-24
RU2006111720A (ru) 2007-10-20
US20050059015A1 (en) 2005-03-17
WO2005026392A3 (en) 2005-08-11
JP5314658B2 (ja) 2013-10-16
ATE480641T1 (de) 2010-09-15
NZ546488A (en) 2009-01-31
US20070086997A1 (en) 2007-04-19
US7176292B2 (en) 2007-02-13
JP2007504825A (ja) 2007-03-08
EP1664346B1 (en) 2010-09-08
US8088730B2 (en) 2012-01-03
IL174195A0 (en) 2006-08-01
AU2004273053A1 (en) 2005-03-24
HK1092841A1 (en) 2007-02-16
CA2538514C (en) 2014-04-08
AU2010212460A1 (en) 2010-09-09
BRPI0414365A (pt) 2006-11-14
JP2011182776A (ja) 2011-09-22
IL174195A (en) 2012-08-30
IL200120A0 (en) 2011-08-01
KR101081040B1 (ko) 2011-11-09
AU2004273053B2 (en) 2010-05-20
KR20060083208A (ko) 2006-07-20
DE602004029061D1 (de) 2010-10-21
CA2538514A1 (en) 2005-03-24
EP1664346A2 (en) 2006-06-07
RU2420583C2 (ru) 2011-06-10

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