JP2007504254A - 植物ステロールおよびスタノールエステルのコレステロール低下性を強化するための化合物および方法 - Google Patents

植物ステロールおよびスタノールエステルのコレステロール低下性を強化するための化合物および方法 Download PDF

Info

Publication number
JP2007504254A
JP2007504254A JP2006525530A JP2006525530A JP2007504254A JP 2007504254 A JP2007504254 A JP 2007504254A JP 2006525530 A JP2006525530 A JP 2006525530A JP 2006525530 A JP2006525530 A JP 2006525530A JP 2007504254 A JP2007504254 A JP 2007504254A
Authority
JP
Japan
Prior art keywords
compound
cholesterol
acid
fatty acid
plant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006525530A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007504254A5 (enExample
Inventor
ピー． カー、ティモシー
Original Assignee
ユニバーシティ オブ ネブラスカ−リンカーン
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユニバーシティ オブ ネブラスカ−リンカーン filed Critical ユニバーシティ オブ ネブラスカ−リンカーン
Publication of JP2007504254A publication Critical patent/JP2007504254A/ja
Publication of JP2007504254A5 publication Critical patent/JP2007504254A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2006525530A 2003-09-05 2004-09-03 植物ステロールおよびスタノールエステルのコレステロール低下性を強化するための化合物および方法 Pending JP2007504254A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50078403P 2003-09-05 2003-09-05
PCT/US2004/029187 WO2005023832A1 (en) 2003-09-05 2004-09-03 Compound and method for enhancing the cholesterol lowering property of plant sterol and stanol esters

Publications (2)

Publication Number Publication Date
JP2007504254A true JP2007504254A (ja) 2007-03-01
JP2007504254A5 JP2007504254A5 (enExample) 2007-10-11

Family

ID=34272993

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006525530A Pending JP2007504254A (ja) 2003-09-05 2004-09-03 植物ステロールおよびスタノールエステルのコレステロール低下性を強化するための化合物および方法

Country Status (7)

Country Link
US (1) US20050085451A1 (enExample)
EP (1) EP1660516A1 (enExample)
JP (1) JP2007504254A (enExample)
KR (1) KR20060083451A (enExample)
AU (1) AU2004270726A1 (enExample)
CA (1) CA2537744A1 (enExample)
WO (1) WO2005023832A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004066938A2 (en) * 2003-01-28 2004-08-12 University Of Georgia Research Foundation, Inc. Method and composition for lowering cholesterol
ES2748136T3 (es) 2007-10-15 2020-03-13 United Animal Health Inc Método para aumentar el rendimiento de las crías

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03169824A (ja) * 1989-10-12 1991-07-23 Procter & Gamble Co:The 血中コレステロールレベルの低下に有用な炭素原子２０〜２４を有する飽和脂肪酸を含有したトリグリセリド
WO2000073407A1 (en) * 1999-05-26 2000-12-07 Asahi Denka Kogyo Kabushiki Kaisha Vegetable sterol-containing fat compositions and process for producing the same
JP2002206100A (ja) * 2000-04-28 2002-07-26 Asahi Denka Kogyo Kk 植物ステロール含有油脂組成物及びその製造方法
JP2003513157A (ja) * 1999-11-05 2003-04-08 ライシオ ベネコール オサケユイチア 食用脂配合物
JP2003516115A (ja) * 1999-06-25 2003-05-13 コグニス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ナノスケールステロールおよびステロールエステルの使用
WO2003064444A1 (en) * 2002-01-31 2003-08-07 Enzymotec Ltd. Fractionation of phytosterol esters in oil
JP2003246746A (ja) * 2002-02-25 2003-09-02 Kurabo Ind Ltd リパーゼ阻害剤およびリパーゼ阻害作用を有する加工食品

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664827B2 (en) * 1991-05-03 1995-12-07 Raisio Benecol Ltd. A substance for lowering high cholesterol level in serum and a method for preparing the same
FI111513B (fi) * 1998-05-06 2003-08-15 Raisio Benecol Oy Uudet fytosteroli- ja fytostanolirasvahappoesterikoostumukset, niitä sisältävät tuotteet sekä menetelmät niiden valmistamiseksi
US5892068A (en) * 1998-08-25 1999-04-06 Mcneil-Ppc, Inc. Preparation of sterol and stanol-esters
DE60132508T2 (de) * 2000-01-31 2008-04-30 Härting S.A. Zusammensetzungen enthaltend Phytosterol- und Policosanolester von Fettsäuren zur Herabsetzung des Cholesterol- und Triglyceridspiegels

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03169824A (ja) * 1989-10-12 1991-07-23 Procter & Gamble Co:The 血中コレステロールレベルの低下に有用な炭素原子２０〜２４を有する飽和脂肪酸を含有したトリグリセリド
WO2000073407A1 (en) * 1999-05-26 2000-12-07 Asahi Denka Kogyo Kabushiki Kaisha Vegetable sterol-containing fat compositions and process for producing the same
JP2003516115A (ja) * 1999-06-25 2003-05-13 コグニス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ナノスケールステロールおよびステロールエステルの使用
JP2003513157A (ja) * 1999-11-05 2003-04-08 ライシオ ベネコール オサケユイチア 食用脂配合物
JP2002206100A (ja) * 2000-04-28 2002-07-26 Asahi Denka Kogyo Kk 植物ステロール含有油脂組成物及びその製造方法
WO2003064444A1 (en) * 2002-01-31 2003-08-07 Enzymotec Ltd. Fractionation of phytosterol esters in oil
JP2005518421A (ja) * 2002-01-31 2005-06-23 エンジィモテック リミテッド 油中のフィトステロールエステルの分別
JP2003246746A (ja) * 2002-02-25 2003-09-02 Kurabo Ind Ltd リパーゼ阻害剤およびリパーゼ阻害作用を有する加工食品

Also Published As

Publication number Publication date
KR20060083451A (ko) 2006-07-20
WO2005023832A1 (en) 2005-03-17
US20050085451A1 (en) 2005-04-21
EP1660516A1 (en) 2006-05-31
CA2537744A1 (en) 2005-03-17
AU2004270726A1 (en) 2005-03-17

Similar Documents

Publication Publication Date Title
Thompson et al. History and development of plant sterol and stanol esters for cholesterol-lowering purposes
AU758747B2 (en) Phytosterol compositions
US8221818B2 (en) Composition with health and nutrition promoting characteristics, containing interestified lipids and phytosterol, and related methods
AU762539B2 (en) Phytosterol and/or phytostanol derivatives
CN100408592C (zh) 油中植物甾醇酯的分馏
US8507466B2 (en) Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy
US6277431B1 (en) Anticholesterolemic edible oil
CN1370180A (zh) 植物甾醇或植物甾烷醇与抗坏血酸的偶联物及其在治疗或预防心血管疾病中的用途
CN101039585B (zh) 用于治疗医学疾病的植物甾醇酯和1,3-甘油二酯的混合物
Carr et al. Cholesterol-lowering phytosterols: factors affecting their use and efficacy
US20060052351A1 (en) Oils enriched with diacylglycerols and phytosterol esters for use in the reduction of blood cholestrol and triglycerides and oxidative stress
Hu et al. Hydrophilic phytosterol derivatives: A short review on structural modifications, cholesterol-lowering activity and safety
WO2003090547A1 (en) A composition comprising waxy acids for effecting serum cholesterol levels
Cilla et al. Development of functional beverages: The case of plant sterol-enriched milk-based fruit beverages
WO2002060272A1 (en) Anticholesterolemic edible oil
US20020192318A1 (en) Anticholesterolemic edible oil
EP2278890B1 (en) Compositions of phytosterols with enhanced bioavailability
JP2007504254A (ja) 植物ステロールおよびスタノールエステルのコレステロール低下性を強化するための化合物および方法
Lin et al. Vegetable oil intake: The distinctive trilateral relationship of bile acid, gut microbiota and health
CN1141934C (zh) 调节血脂保健油
He et al. Application of phytosterols in management of plasma cholesterol
Ho et al. Beneficial effects of plant sterols/stanols-containing milk powder on lipid metabolism in hamsters
Burn et al. Food as a source of health enhancing compounds
AbuMweis et al. Cholesterol-lowering action of plant sterol-enriched products
Kim et al. Dietary structured lipids and phytosteryl esters: blood lipids and cardiovascular status in spontaneously hypertensive rats

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070827

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070827

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101116

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110426