JP2007503818A5 - - Google Patents

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Publication number
JP2007503818A5
JP2007503818A5 JP2006524947A JP2006524947A JP2007503818A5 JP 2007503818 A5 JP2007503818 A5 JP 2007503818A5 JP 2006524947 A JP2006524947 A JP 2006524947A JP 2006524947 A JP2006524947 A JP 2006524947A JP 2007503818 A5 JP2007503818 A5 JP 2007503818A5
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JP
Japan
Prior art keywords
metabolic
kit
product
analytes
substrates
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JP2006524947A
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English (en)
Japanese (ja)
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JP2007503818A (ja
JP4838129B2 (ja
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Priority claimed from US10/652,732 external-priority patent/US20050048499A1/en
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Publication of JP2007503818A publication Critical patent/JP2007503818A/ja
Publication of JP2007503818A5 publication Critical patent/JP2007503818A5/ja
Application granted granted Critical
Publication of JP4838129B2 publication Critical patent/JP4838129B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2006524947A 2003-08-29 2004-08-30 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法 Expired - Fee Related JP4838129B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/652,732 US20050048499A1 (en) 2003-08-29 2003-08-29 Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns
US10/652,732 2003-08-29
PCT/US2004/028238 WO2005021779A1 (en) 2003-08-29 2004-08-30 Mass spectrometry methods for simultaneous detection of metabolic enzyme activity and metabolite levels

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011126859A Division JP2011167208A (ja) 2003-08-29 2011-06-07 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法

Publications (3)

Publication Number Publication Date
JP2007503818A JP2007503818A (ja) 2007-03-01
JP2007503818A5 true JP2007503818A5 (https=) 2007-10-18
JP4838129B2 JP4838129B2 (ja) 2011-12-14

Family

ID=34217718

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006524947A Expired - Fee Related JP4838129B2 (ja) 2003-08-29 2004-08-30 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法
JP2011126859A Pending JP2011167208A (ja) 2003-08-29 2011-06-07 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011126859A Pending JP2011167208A (ja) 2003-08-29 2011-06-07 代謝酵素活性及び代謝産物レベルの同時検出のための質量分析法

Country Status (7)

Country Link
US (4) US20050048499A1 (https=)
EP (1) EP1664325B1 (https=)
JP (2) JP4838129B2 (https=)
AU (1) AU2004269410B2 (https=)
CA (1) CA2537034C (https=)
ES (1) ES2527306T3 (https=)
WO (1) WO2005021779A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485435B2 (en) * 2004-08-30 2009-02-03 Perkinelmer Las, Inc. Simultaneous detection of metabolic enzyme activity and metabolite levels
US20050048499A1 (en) * 2003-08-29 2005-03-03 Perkin Elmer Life Sciences, Inc. Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns
GB0409676D0 (en) * 2004-04-30 2004-06-02 Micromass Ltd Mass spectrometer
CA2564279C (en) * 2004-04-30 2013-09-24 Micromass Uk Limited Mass spectrometer
DE602005016899D1 (de) * 2005-05-20 2009-11-12 Germediq Forsch & Entw Ges Mbh Verfahren zur Bestimmung von kardiovaskulären Risikofaktoren
JP5005955B2 (ja) * 2006-05-24 2012-08-22 田辺三菱製薬株式会社 被験物質の脂質代謝異常症誘発可能性を予測する方法
EP2657705A3 (en) 2006-09-19 2013-12-25 Metabolon Inc. Biomarkers for prostate cancer and methods using the same
US7923257B2 (en) * 2007-05-04 2011-04-12 Perkinelmer Health Sciences, Inc. Detecting isomers using differential derivatization mass spectrometry
CN101796408B (zh) * 2007-06-29 2014-05-07 奎斯特诊断投资公司 用液相层析-质谱法分析体液内的氨基酸
JP5385914B2 (ja) * 2007-12-05 2014-01-08 キングス カレッジ ロンドン 方法及び組成物
FI20090100A0 (fi) * 2009-03-16 2009-03-16 Wallac Oy Biotinidaasimääritys
DE112015001169T5 (de) * 2014-03-10 2016-12-22 Micromass Uk Limited Bestätigung unter Verwendung einer Mehrzahl von Kollisionsquerschnitts-("CCS")-Messungen
JP6055957B2 (ja) 2014-03-31 2016-12-27 積水メディカル株式会社 アシルカルニチン組成物
WO2016171182A1 (ja) * 2015-04-24 2016-10-27 株式会社資生堂 分析方法及び内部標準物質
JP6101385B2 (ja) * 2015-04-24 2017-03-22 株式会社 資生堂 分析方法
CN105510583A (zh) * 2015-11-25 2016-04-20 北京中科非凡生物技术有限公司 检测生物素酶酶活性的试剂盒
WO2017180652A1 (en) * 2016-04-11 2017-10-19 Applied Proteomics, Inc. Mass spectrometric data analysis workflow
WO2018174858A1 (en) * 2017-03-21 2018-09-27 Mprobe Inc. Clinical method for the population screening of adult metabolic disorder associated with chronic human disease
CN111272888A (zh) * 2020-01-10 2020-06-12 山东英盛生物技术有限公司 一种新生儿血片中氨基酸及肉碱筛查预处理方法
US20220395767A1 (en) * 2021-06-15 2022-12-15 Perkinelmer Health Sciences, Inc. Enhancing lcms analyte signals
CN114121275B (zh) * 2021-11-02 2024-09-27 浙江大学 一种基于大数据遗传代谢病筛查效率提升的智能分析方法
EP4679082A1 (en) 2024-07-10 2026-01-14 Masdiag Sp. z o.o. Method for improved determination of the acylcarnitine profile in biological material

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096812A (en) * 1989-06-08 1992-03-17 Osborn Laboratories, Inc. Assay method for gamma glutamyltransferase (GGT) in liquid blood and dried blood
US5538857A (en) * 1994-06-01 1996-07-23 Isolab, Inc. Assay for enzyme activity from a red blood sample using a direct microfluorometric assay
US5629210A (en) * 1995-06-02 1997-05-13 University Of Pittsburgh Of The Commonwealth System Of Higher Education Rapid screening test for smith-lemli-opitz syndrome
DE69912444T3 (de) * 1998-08-25 2010-05-06 University Of Washington, Seattle Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
MXPA01004266A (es) 1998-10-30 2002-06-04 Burstein Technologies Inc Discos opticos rastreables con material de analito concurrentemente legibles.
US6455321B1 (en) * 1999-01-30 2002-09-24 Neo Gen Screening, Inc. Method for interpreting tandem mass spectrometry data for clinical diagnosis
US6258605B1 (en) * 1999-03-26 2001-07-10 Neo Gen Screening, Inc. Clinical method for the genetic screening of newborns using tandem mass spectrometry
DE60031357T2 (de) * 1999-12-29 2007-08-30 PerkinElmer Life Sciences, Inc., Norton Geräte, Kits und Verfahren zum Testen von Körperflüssigkeiten zum Screening vonNeugeborenen durch Tandem-Massenspektrometrie-Kits
US20050048499A1 (en) * 2003-08-29 2005-03-03 Perkin Elmer Life Sciences, Inc. Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns

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