JP2007503812A5 - - Google Patents
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- Publication number
- JP2007503812A5 JP2007503812A5 JP2006524917A JP2006524917A JP2007503812A5 JP 2007503812 A5 JP2007503812 A5 JP 2007503812A5 JP 2006524917 A JP2006524917 A JP 2006524917A JP 2006524917 A JP2006524917 A JP 2006524917A JP 2007503812 A5 JP2007503812 A5 JP 2007503812A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- function
- codon
- enhanced
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 claims 26
- 102000004169 proteins and genes Human genes 0.000 claims 22
- 108020004705 Codon Proteins 0.000 claims 11
- 238000000034 method Methods 0.000 claims 7
- 108700005078 Synthetic Genes Proteins 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 238000010367 cloning Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 210000003000 inclusion body Anatomy 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49892303P | 2003-08-28 | 2003-08-28 | |
| US49844903P | 2003-08-28 | 2003-08-28 | |
| US49878503P | 2003-08-28 | 2003-08-28 | |
| IN279MU2004 | 2004-03-05 | ||
| IN280MU2004 | 2004-03-05 | ||
| PCT/US2004/028068 WO2005021777A2 (en) | 2003-08-28 | 2004-08-26 | Uses of spatial configuration to modulate protein function |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011011325A Division JP2011083292A (ja) | 2003-08-28 | 2011-01-21 | 空間構造によるタンパク質の機能の調節 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007503812A JP2007503812A (ja) | 2007-03-01 |
| JP2007503812A5 true JP2007503812A5 (https=) | 2007-12-06 |
Family
ID=34280101
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006524917A Pending JP2007503812A (ja) | 2003-08-28 | 2004-08-26 | 空間構造によるタンパク質の機能の調節 |
| JP2006524916A Expired - Fee Related JP5663768B2 (ja) | 2003-08-28 | 2004-08-26 | 空間構造が変えられるインターフェロン及びその応用 |
| JP2011011325A Pending JP2011083292A (ja) | 2003-08-28 | 2011-01-21 | 空間構造によるタンパク質の機能の調節 |
| JP2012121307A Expired - Fee Related JP5709800B2 (ja) | 2003-08-28 | 2012-05-28 | 変えられた空間構造を備えるインターフェロン及びその応用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006524916A Expired - Fee Related JP5663768B2 (ja) | 2003-08-28 | 2004-08-26 | 空間構造が変えられるインターフェロン及びその応用 |
| JP2011011325A Pending JP2011083292A (ja) | 2003-08-28 | 2011-01-21 | 空間構造によるタンパク質の機能の調節 |
| JP2012121307A Expired - Fee Related JP5709800B2 (ja) | 2003-08-28 | 2012-05-28 | 変えられた空間構造を備えるインターフェロン及びその応用 |
Country Status (7)
| Country | Link |
|---|---|
| EP (3) | EP1663110B1 (https=) |
| JP (4) | JP2007503812A (https=) |
| KR (2) | KR20060130009A (https=) |
| AU (2) | AU2004269390A1 (https=) |
| CA (2) | CA2535982C (https=) |
| PL (2) | PL1663110T3 (https=) |
| WO (2) | WO2005021777A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1245215C (zh) | 2001-02-28 | 2006-03-15 | 四川省生物工程研究中心 | 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂 |
| US8551469B2 (en) | 2001-02-28 | 2013-10-08 | Superlab Far East Limited | Treatment of tumors and viral diseases with recombinant interferon alpha |
| KR20060130009A (ko) * | 2003-08-28 | 2006-12-18 | 휴이양테크 (유에스에이), 인크. | 변경된 공간 구조를 갖는 인터페론의 용도 |
| US7585647B2 (en) | 2003-08-28 | 2009-09-08 | Guangwen Wei | Nucleic acid encoding recombinant interferon |
| WO2006076014A2 (en) * | 2004-04-30 | 2006-07-20 | Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Interferon-alpha constructs for use in the treatment of sars |
| AU2006257286B2 (en) * | 2005-03-09 | 2012-08-16 | Superlab Far East Limited | Uses of recombinant super-compound interferons |
| CN102101886A (zh) * | 2009-12-18 | 2011-06-22 | 四川辉阳生命工程股份有限公司 | 构象改变的重组干扰素晶体、其三维结构及应用 |
| TW201427681A (zh) * | 2013-01-07 | 2014-07-16 | Superlab Far East Ltd | 用空間構象改變的重組干擾素治療腫瘤的方法 |
| CN111363726A (zh) | 2018-12-26 | 2020-07-03 | 上海元宋生物技术有限公司 | 表达干扰素的溶瘤病毒及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6936694B1 (en) * | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
| US5372808A (en) | 1990-10-17 | 1994-12-13 | Amgen Inc. | Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect |
| CA2232230C (en) * | 1995-10-13 | 2005-06-28 | Ralph H. Lambalot | Phosphopantetheinyl transferases and uses thereof |
| US5874304A (en) * | 1996-01-18 | 1999-02-23 | University Of Florida Research Foundation, Inc. | Humanized green fluorescent protein genes and methods |
| US20020043262A1 (en) * | 2000-08-22 | 2002-04-18 | Alan Langford | Spray device |
| US7666995B2 (en) * | 2000-11-03 | 2010-02-23 | Pestka Biomedical Laboratories | Interferons, uses and compositions related thereto |
| CN1245215C (zh) * | 2001-02-28 | 2006-03-15 | 四川省生物工程研究中心 | 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂 |
| KR20060130009A (ko) * | 2003-08-28 | 2006-12-18 | 휴이양테크 (유에스에이), 인크. | 변경된 공간 구조를 갖는 인터페론의 용도 |
-
2004
- 2004-08-26 KR KR1020067003699A patent/KR20060130009A/ko not_active Ceased
- 2004-08-26 PL PL04809634T patent/PL1663110T3/pl unknown
- 2004-08-26 EP EP04809634.1A patent/EP1663110B1/en not_active Expired - Lifetime
- 2004-08-26 JP JP2006524917A patent/JP2007503812A/ja active Pending
- 2004-08-26 EP EP04782529A patent/EP1670817A4/en not_active Ceased
- 2004-08-26 AU AU2004269390A patent/AU2004269390A1/en not_active Abandoned
- 2004-08-26 CA CA2535982A patent/CA2535982C/en not_active Expired - Lifetime
- 2004-08-26 EP EP10193126.9A patent/EP2325202B1/en not_active Expired - Lifetime
- 2004-08-26 PL PL10193126T patent/PL2325202T3/pl unknown
- 2004-08-26 CA CA002535902A patent/CA2535902A1/en not_active Abandoned
- 2004-08-26 JP JP2006524916A patent/JP5663768B2/ja not_active Expired - Fee Related
- 2004-08-26 KR KR1020067003700A patent/KR20060133949A/ko not_active Ceased
- 2004-08-26 WO PCT/US2004/028068 patent/WO2005021777A2/en not_active Ceased
- 2004-08-26 AU AU2004279350A patent/AU2004279350B2/en not_active Expired
- 2004-08-26 WO PCT/US2004/028067 patent/WO2005034853A2/en not_active Ceased
-
2011
- 2011-01-21 JP JP2011011325A patent/JP2011083292A/ja active Pending
-
2012
- 2012-05-28 JP JP2012121307A patent/JP5709800B2/ja not_active Expired - Fee Related
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