JP2007503812A - 空間構造によるタンパク質の機能の調節 - Google Patents

空間構造によるタンパク質の機能の調節 Download PDF

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JP2007503812A
JP2007503812A JP2006524917A JP2006524917A JP2007503812A JP 2007503812 A JP2007503812 A JP 2007503812A JP 2006524917 A JP2006524917 A JP 2006524917A JP 2006524917 A JP2006524917 A JP 2006524917A JP 2007503812 A JP2007503812 A JP 2007503812A
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protein
codon
function
gene
enhanced
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JP2007503812A5 (OSRAM
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ウェイ,グアンウェン
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ヒュイヤンテック(ユーエスエー),インク.
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2299/00Coordinates from 3D structures of peptides, e.g. proteins or enzymes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Veterinary Medicine (AREA)
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  • Engineering & Computer Science (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2006524917A 2003-08-28 2004-08-26 空間構造によるタンパク質の機能の調節 Pending JP2007503812A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US49878503P 2003-08-28 2003-08-28
US49844903P 2003-08-28 2003-08-28
US49892303P 2003-08-28 2003-08-28
IN279MU2004 2004-03-05
IN280MU2004 2004-03-05
PCT/US2004/028068 WO2005021777A2 (en) 2003-08-28 2004-08-26 Uses of spatial configuration to modulate protein function

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011011325A Division JP2011083292A (ja) 2003-08-28 2011-01-21 空間構造によるタンパク質の機能の調節

Publications (2)

Publication Number Publication Date
JP2007503812A true JP2007503812A (ja) 2007-03-01
JP2007503812A5 JP2007503812A5 (OSRAM) 2007-12-06

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ID=34280101

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2006524917A Pending JP2007503812A (ja) 2003-08-28 2004-08-26 空間構造によるタンパク質の機能の調節
JP2006524916A Expired - Fee Related JP5663768B2 (ja) 2003-08-28 2004-08-26 空間構造が変えられるインターフェロン及びその応用
JP2011011325A Pending JP2011083292A (ja) 2003-08-28 2011-01-21 空間構造によるタンパク質の機能の調節
JP2012121307A Expired - Fee Related JP5709800B2 (ja) 2003-08-28 2012-05-28 変えられた空間構造を備えるインターフェロン及びその応用

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2006524916A Expired - Fee Related JP5663768B2 (ja) 2003-08-28 2004-08-26 空間構造が変えられるインターフェロン及びその応用
JP2011011325A Pending JP2011083292A (ja) 2003-08-28 2011-01-21 空間構造によるタンパク質の機能の調節
JP2012121307A Expired - Fee Related JP5709800B2 (ja) 2003-08-28 2012-05-28 変えられた空間構造を備えるインターフェロン及びその応用

Country Status (7)

Country Link
EP (3) EP2325202B1 (OSRAM)
JP (4) JP2007503812A (OSRAM)
KR (2) KR20060133949A (OSRAM)
AU (2) AU2004269390A1 (OSRAM)
CA (2) CA2535902A1 (OSRAM)
PL (2) PL2325202T3 (OSRAM)
WO (2) WO2005021777A2 (OSRAM)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013514279A (ja) * 2009-12-18 2013-04-25 四川▲輝▼▲陽▼生命工程股▲分▼有限公司 変更された空間構成を有する結晶性組換型インターフェロン、その三次元構造、およびその使用
JP2016506413A (ja) * 2013-01-07 2016-03-03 スーパーラブ ファー イースト リミテッド 空間配置が変化した組換えインターフェロンを用いる腫瘍治療の方法
JP2022516129A (ja) * 2018-12-26 2022-02-24 上海元宋生物技術有限公司 インターフェロンを発現する腫瘍溶解性ウイルス及びその応用

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1245215C (zh) 2001-02-28 2006-03-15 四川省生物工程研究中心 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂
US8551469B2 (en) 2001-02-28 2013-10-08 Superlab Far East Limited Treatment of tumors and viral diseases with recombinant interferon alpha
WO2005021777A2 (en) * 2003-08-28 2005-03-10 Huiyangtech (Usa), Inc. Uses of spatial configuration to modulate protein function
US7585647B2 (en) 2003-08-28 2009-09-08 Guangwen Wei Nucleic acid encoding recombinant interferon
WO2006076014A2 (en) * 2004-04-30 2006-07-20 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Interferon-alpha constructs for use in the treatment of sars
EP1868636A4 (en) * 2005-03-09 2012-03-28 Guangwen Wei USE OF RECOMBINANT SUPERCOMPOSE INTERFERONS

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11514868A (ja) * 1995-10-13 1999-12-21 プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ ホスホパンテテイニルトランスフェラーゼおよびその使用
JP2000503536A (ja) * 1996-01-18 2000-03-28 ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイテッド ヒト化グリーン蛍光タンパク質遺伝子および方法
WO2002080958A1 (fr) * 2001-02-28 2002-10-17 Sichuan Biotechnology Research Center Interferon supercompose de recombinaison utilise comme inhibiteur de l'antigene de surface et de l'antigene e de l'hepatite b

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
US5372808A (en) 1990-10-17 1994-12-13 Amgen Inc. Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect
US20020043262A1 (en) * 2000-08-22 2002-04-18 Alan Langford Spray device
IL155741A0 (en) * 2000-11-03 2003-12-23 Pbl Biomedical Lab Interferons, uses and compositions related thereto
WO2005021777A2 (en) * 2003-08-28 2005-03-10 Huiyangtech (Usa), Inc. Uses of spatial configuration to modulate protein function

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11514868A (ja) * 1995-10-13 1999-12-21 プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ ホスホパンテテイニルトランスフェラーゼおよびその使用
JP2000503536A (ja) * 1996-01-18 2000-03-28 ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイテッド ヒト化グリーン蛍光タンパク質遺伝子および方法
WO2002080958A1 (fr) * 2001-02-28 2002-10-17 Sichuan Biotechnology Research Center Interferon supercompose de recombinaison utilise comme inhibiteur de l'antigene de surface et de l'antigene e de l'hepatite b

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013514279A (ja) * 2009-12-18 2013-04-25 四川▲輝▼▲陽▼生命工程股▲分▼有限公司 変更された空間構成を有する結晶性組換型インターフェロン、その三次元構造、およびその使用
JP2016128507A (ja) * 2009-12-18 2016-07-14 スーパーラブ ファー イースト リミテッド 変更された空間構成を有する結晶性組換型インターフェロン、その三次元構造、およびその使用
JP2016506413A (ja) * 2013-01-07 2016-03-03 スーパーラブ ファー イースト リミテッド 空間配置が変化した組換えインターフェロンを用いる腫瘍治療の方法
JP2022516129A (ja) * 2018-12-26 2022-02-24 上海元宋生物技術有限公司 インターフェロンを発現する腫瘍溶解性ウイルス及びその応用
JP7378840B2 (ja) 2018-12-26 2023-11-14 上海元宋生物技術有限公司 インターフェロンを発現する腫瘍溶解性ウイルス及びその応用
US12319931B2 (en) 2018-12-26 2025-06-03 Shanghai Yuansong Biotechnology Co. Ltd. Oncolytic virus expressing interferon and application therefor

Also Published As

Publication number Publication date
EP2325202B1 (en) 2014-10-22
JP5709800B2 (ja) 2015-04-30
WO2005021777A2 (en) 2005-03-10
PL2325202T3 (pl) 2015-03-31
KR20060130009A (ko) 2006-12-18
AU2004279350B2 (en) 2011-03-10
EP1670817A2 (en) 2006-06-21
EP1663110A2 (en) 2006-06-07
CA2535982A1 (en) 2005-04-21
HK1091756A1 (en) 2007-01-26
AU2004269390A1 (en) 2005-03-10
HK1158231A1 (en) 2012-09-14
CA2535982C (en) 2016-11-29
PL1663110T3 (pl) 2014-07-31
JP2011083292A (ja) 2011-04-28
EP1663110B1 (en) 2013-12-18
WO2005034853A3 (en) 2006-04-27
WO2005034853A2 (en) 2005-04-21
EP1670817A4 (en) 2008-07-16
CA2535902A1 (en) 2005-03-10
WO2005021777A3 (en) 2005-05-12
EP2325202A1 (en) 2011-05-25
JP2012162567A (ja) 2012-08-30
JP5663768B2 (ja) 2015-02-04
AU2004279350A1 (en) 2005-04-21
JP2007516214A (ja) 2007-06-21
EP1663110A4 (en) 2008-07-16
KR20060133949A (ko) 2006-12-27

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