JP2007502309A - クマリン系化合物及び抗真菌薬物 - Google Patents
クマリン系化合物及び抗真菌薬物 Download PDFInfo
- Publication number
- JP2007502309A JP2007502309A JP2006529556A JP2006529556A JP2007502309A JP 2007502309 A JP2007502309 A JP 2007502309A JP 2006529556 A JP2006529556 A JP 2006529556A JP 2006529556 A JP2006529556 A JP 2006529556A JP 2007502309 A JP2007502309 A JP 2007502309A
- Authority
- JP
- Japan
- Prior art keywords
- group
- coumarin
- halogen
- compound
- phosphine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC(*)(C=CC=C1)C=C1C(c(cc(*)cc1*)c1O1)=CC1=O Chemical compound CC(*)(C=CC=C1)C=C1C(c(cc(*)cc1*)c1O1)=CC1=O 0.000 description 1
- SRXDLJDZODAADY-UHFFFAOYSA-N COc(c(O)c1OC)cc(C(C(c(c(O2)c3OC)cc(OC)c3O)=CC2=O)=C2)c1OC2=O Chemical compound COc(c(O)c1OC)cc(C(C(c(c(O2)c3OC)cc(OC)c3O)=CC2=O)=C2)c1OC2=O SRXDLJDZODAADY-UHFFFAOYSA-N 0.000 description 1
- ORBJFNDBFXLSGC-UHFFFAOYSA-N COc(cc(C=O)c(C(c1ccccc1O1)=CC1=O)c1OC)c1OC Chemical compound COc(cc(C=O)c(C(c1ccccc1O1)=CC1=O)c1OC)c1OC ORBJFNDBFXLSGC-UHFFFAOYSA-N 0.000 description 1
- DPLUODNKLYSCGA-UHFFFAOYSA-N COc1ccc(C=O)c(C(c2ccccc2O2)=CC2=O)c1OC Chemical compound COc1ccc(C=O)c(C(c2ccccc2O2)=CC2=O)c1OC DPLUODNKLYSCGA-UHFFFAOYSA-N 0.000 description 1
- YQUJYAPRUXAVLL-UHFFFAOYSA-N O=Cc(c(C(c1cc(F)ccc1O1)=CC1=O)c1)cc2c1OCO2 Chemical compound O=Cc(c(C(c1cc(F)ccc1O1)=CC1=O)c1)cc2c1OCO2 YQUJYAPRUXAVLL-UHFFFAOYSA-N 0.000 description 1
- CNBIGJUUIGDFKS-UHFFFAOYSA-N Oc(cc1O2)ccc1C(C(c(c(O1)c3)ccc3O)=CC1=O)=CC2=O Chemical compound Oc(cc1O2)ccc1C(C(c(c(O1)c3)ccc3O)=CC1=O)=CC2=O CNBIGJUUIGDFKS-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB03116952XA CN1281599C (zh) | 2003-05-15 | 2003-05-15 | 香豆素类化合物和合成方法 |
| PCT/CN2004/000491 WO2004101543A1 (en) | 2003-05-15 | 2004-05-17 | Coumarins compounds, the preparation and the use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007502309A true JP2007502309A (ja) | 2007-02-08 |
| JP2007502309A5 JP2007502309A5 (enExample) | 2007-07-05 |
Family
ID=28684306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006529556A Pending JP2007502309A (ja) | 2003-05-15 | 2004-05-17 | クマリン系化合物及び抗真菌薬物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7259265B2 (enExample) |
| EP (1) | EP1634878A4 (enExample) |
| JP (1) | JP2007502309A (enExample) |
| CN (1) | CN1281599C (enExample) |
| WO (1) | WO2004101543A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007513073A (ja) * | 2003-11-04 | 2007-05-24 | カイロン コーポレイション | B細胞に関連する癌に対する治療方法 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008085995A1 (en) * | 2007-01-09 | 2008-07-17 | Merck & Co., Inc. | Anthelmintic flavones from struthiola argenta |
| CN101497593B (zh) * | 2009-03-18 | 2011-09-21 | 华南理工大学 | 5-羟基香豆素和吡喃型香豆素类化合物及合成方法与应用 |
| CN101869106A (zh) * | 2010-06-22 | 2010-10-27 | 北京农学院 | 一种伞形花内酯植物杀真菌剂及其用途 |
| CN101869107A (zh) * | 2010-06-22 | 2010-10-27 | 北京农学院 | 一种东莨菪内酯植物杀螨剂及其用途 |
| US9896622B2 (en) * | 2016-03-03 | 2018-02-20 | EWHA University—Industry Collaboration Foundation | Coumarin-based derivative compound, preparing method thereof, and fluorescent composition containing the same |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1067768A (ja) * | 1996-07-02 | 1998-03-10 | Pliva Pharmaceut Kemijska Prehrambena I Kozmetind Dionicko Drustvo | 新規なクマリン誘導体及びその製造方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2596107A (en) * | 1948-12-04 | 1952-05-13 | Schieffelin & Co | Use of carbalkoxy hydroxy benzo-coumarin against fungi |
| GB1518291A (en) * | 1975-04-11 | 1978-07-19 | Fisons Ltd | Process for the preparation of coumarin derivatives |
| JP2876129B2 (ja) * | 1988-10-22 | 1999-03-31 | 東洋ファルマー株式会社 | 7―カルボキシメトキシ―4―フェニルクマリン誘導体とその製法及び用途 |
| DE4337906A1 (de) * | 1993-11-08 | 1995-05-11 | Cassella Ag | Verwendung von Cumarinderivaten |
| PL187175B1 (pl) * | 1995-10-13 | 2004-05-31 | Bayer Cropscience Ltd | Bicykliczne związki heterocykliczne, kompozycja grzybobójcza je zawierająca i ich zastosowanie |
| WO1998004572A1 (en) * | 1996-07-31 | 1998-02-05 | Kureha Chemical Industry Co., Ltd. | Novel coumarin derivatives and glycosides thereof, and processes for the preparation of both |
| IT1289238B1 (it) * | 1996-12-10 | 1998-09-29 | Bio S S P A Ora Bio S S R L | Composizioni farmaceutiche per il trattamento di infezioni virali comprendenti una 4 arilcumarina |
| IT1317356B1 (it) * | 2000-07-31 | 2003-06-16 | Fidia S P A Ora Fidia Farmaceu | Derivati della cumarina e relativi sali, processo per la loropreparazione e loro impiego in campo farmaceutico. |
-
2003
- 2003-05-15 CN CNB03116952XA patent/CN1281599C/zh not_active Expired - Fee Related
-
2004
- 2004-05-17 JP JP2006529556A patent/JP2007502309A/ja active Pending
- 2004-05-17 EP EP04733292A patent/EP1634878A4/en not_active Withdrawn
- 2004-05-17 WO PCT/CN2004/000491 patent/WO2004101543A1/zh not_active Ceased
-
2005
- 2005-11-15 US US11/273,372 patent/US7259265B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1067768A (ja) * | 1996-07-02 | 1998-03-10 | Pliva Pharmaceut Kemijska Prehrambena I Kozmetind Dionicko Drustvo | 新規なクマリン誘導体及びその製造方法 |
Non-Patent Citations (1)
| Title |
|---|
| JPN6010065001, Planta Medica, 1998, Vol.64, p.774−775 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007513073A (ja) * | 2003-11-04 | 2007-05-24 | カイロン コーポレイション | B細胞に関連する癌に対する治療方法 |
| JP4810431B2 (ja) * | 2003-11-04 | 2011-11-09 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | B細胞に関連する癌に対する治療方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1281599C (zh) | 2006-10-25 |
| CN1450062A (zh) | 2003-10-22 |
| EP1634878A1 (en) | 2006-03-15 |
| US20060063806A1 (en) | 2006-03-23 |
| EP1634878A4 (en) | 2008-02-27 |
| WO2004101543A1 (en) | 2004-11-25 |
| US7259265B2 (en) | 2007-08-21 |
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