JP2007502309A5 - - Google Patents
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- Publication number
- JP2007502309A5 JP2007502309A5 JP2006529556A JP2006529556A JP2007502309A5 JP 2007502309 A5 JP2007502309 A5 JP 2007502309A5 JP 2006529556 A JP2006529556 A JP 2006529556A JP 2006529556 A JP2006529556 A JP 2006529556A JP 2007502309 A5 JP2007502309 A5 JP 2007502309A5
- Authority
- JP
- Japan
- Prior art keywords
- coumarin
- group
- drug
- hydrocarbon group
- fungal resistance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N benzo-alpha-pyrone Natural products C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 claims 2
- 229960000956 coumarin Drugs 0.000 claims 2
- 235000001671 coumarin Nutrition 0.000 claims 2
- 230000002538 fungal effect Effects 0.000 claims 2
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 2
- GOLORTLGFDVFDW-UHFFFAOYSA-N 3-(1h-benzimidazol-2-yl)-7-(diethylamino)chromen-2-one Chemical group C1=CC=C2NC(C3=CC4=CC=C(C=C4OC3=O)N(CC)CC)=NC2=C1 GOLORTLGFDVFDW-UHFFFAOYSA-N 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 208000010195 Onychomycosis Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- -1 coumarin compound Chemical class 0.000 claims 1
- 125000000332 coumarinyl group Chemical group O1C(=O)C(=CC2=CC=CC=C12)* 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 201000005882 tinea unguium Diseases 0.000 claims 1
- SRXDLJDZODAADY-UHFFFAOYSA-N COc(cc(C(C(c(c(O1)c2OC)cc(OC)c2O)=CC1=O)=CC(O1)=O)c1c1OC)c1O Chemical compound COc(cc(C(C(c(c(O1)c2OC)cc(OC)c2O)=CC1=O)=CC(O1)=O)c1c1OC)c1O SRXDLJDZODAADY-UHFFFAOYSA-N 0.000 description 1
- BKKVOYURHLNRNX-UHFFFAOYSA-N COc(cc1C(C(c2cc(OC)ccc2O2)=CC2=O)=C2)ccc1OC2=O Chemical compound COc(cc1C(C(c2cc(OC)ccc2O2)=CC2=O)=C2)ccc1OC2=O BKKVOYURHLNRNX-UHFFFAOYSA-N 0.000 description 1
- ZSTDEFKPYMMEBI-UHFFFAOYSA-N Cc(cc1C(C(c2cc(C)ccc2O2)=CC2=O)=C2)ccc1OC2=O Chemical compound Cc(cc1C(C(c2cc(C)ccc2O2)=CC2=O)=C2)ccc1OC2=O ZSTDEFKPYMMEBI-UHFFFAOYSA-N 0.000 description 1
- 0 Cc1c(*)c(OC(C=C2*)=O)c2c(*)c1* Chemical compound Cc1c(*)c(OC(C=C2*)=O)c2c(*)c1* 0.000 description 1
- MGGVHZSKYCHHJV-UHFFFAOYSA-N O=C(C=C(c1c2)C(c3cc(F)ccc3O3)=CC3=O)Oc1ccc2F Chemical compound O=C(C=C(c1c2)C(c3cc(F)ccc3O3)=CC3=O)Oc1ccc2F MGGVHZSKYCHHJV-UHFFFAOYSA-N 0.000 description 1
- GXXIMPKQYVNGAY-UHFFFAOYSA-N O=C1Oc2ccccc2C(C(c2ccccc2O2)=CC2=O)=C1 Chemical compound O=C1Oc2ccccc2C(C(c2ccccc2O2)=CC2=O)=C1 GXXIMPKQYVNGAY-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB03116952XA CN1281599C (zh) | 2003-05-15 | 2003-05-15 | 香豆素类化合物和合成方法 |
| PCT/CN2004/000491 WO2004101543A1 (en) | 2003-05-15 | 2004-05-17 | Coumarins compounds, the preparation and the use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007502309A JP2007502309A (ja) | 2007-02-08 |
| JP2007502309A5 true JP2007502309A5 (enExample) | 2007-07-05 |
Family
ID=28684306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006529556A Pending JP2007502309A (ja) | 2003-05-15 | 2004-05-17 | クマリン系化合物及び抗真菌薬物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7259265B2 (enExample) |
| EP (1) | EP1634878A4 (enExample) |
| JP (1) | JP2007502309A (enExample) |
| CN (1) | CN1281599C (enExample) |
| WO (1) | WO2004101543A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1684869T3 (da) * | 2003-11-04 | 2011-10-31 | Novartis Vaccines & Diagnostic | Fremgangsmåde til terapi af B-celle-relaterede cancersygdomme |
| WO2008085995A1 (en) * | 2007-01-09 | 2008-07-17 | Merck & Co., Inc. | Anthelmintic flavones from struthiola argenta |
| CN101497593B (zh) * | 2009-03-18 | 2011-09-21 | 华南理工大学 | 5-羟基香豆素和吡喃型香豆素类化合物及合成方法与应用 |
| CN101869107A (zh) * | 2010-06-22 | 2010-10-27 | 北京农学院 | 一种东莨菪内酯植物杀螨剂及其用途 |
| CN101869106A (zh) * | 2010-06-22 | 2010-10-27 | 北京农学院 | 一种伞形花内酯植物杀真菌剂及其用途 |
| US9896622B2 (en) * | 2016-03-03 | 2018-02-20 | EWHA University—Industry Collaboration Foundation | Coumarin-based derivative compound, preparing method thereof, and fluorescent composition containing the same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2596107A (en) * | 1948-12-04 | 1952-05-13 | Schieffelin & Co | Use of carbalkoxy hydroxy benzo-coumarin against fungi |
| GB1518291A (en) * | 1975-04-11 | 1978-07-19 | Fisons Ltd | Process for the preparation of coumarin derivatives |
| JP2876129B2 (ja) * | 1988-10-22 | 1999-03-31 | 東洋ファルマー株式会社 | ７―カルボキシメトキシ―４―フェニルクマリン誘導体とその製法及び用途 |
| DE4337906A1 (de) * | 1993-11-08 | 1995-05-11 | Cassella Ag | Verwendung von Cumarinderivaten |
| IL123701A (en) * | 1995-10-13 | 2002-03-10 | Agrevo Uk Ltd | Heterocyclic fungicides and a number of new compounds |
| HRP960308A2 (en) * | 1996-07-02 | 1998-08-31 | Ljerka Poljak | New coumarine derivatives, process for the preparation thereof and their use |
| WO1998004572A1 (en) * | 1996-07-31 | 1998-02-05 | Kureha Chemical Industry Co., Ltd. | Novel coumarin derivatives and glycosides thereof, and processes for the preparation of both |
| IT1289238B1 (it) * | 1996-12-10 | 1998-09-29 | Bio S S P A Ora Bio S S R L | Composizioni farmaceutiche per il trattamento di infezioni virali comprendenti una 4 arilcumarina |
| IT1317356B1 (it) * | 2000-07-31 | 2003-06-16 | Fidia S P A Ora Fidia Farmaceu | Derivati della cumarina e relativi sali, processo per la loropreparazione e loro impiego in campo farmaceutico. |
-
2003
- 2003-05-15 CN CNB03116952XA patent/CN1281599C/zh not_active Expired - Fee Related
-
2004
- 2004-05-17 JP JP2006529556A patent/JP2007502309A/ja active Pending
- 2004-05-17 WO PCT/CN2004/000491 patent/WO2004101543A1/zh not_active Ceased
- 2004-05-17 EP EP04733292A patent/EP1634878A4/en not_active Withdrawn
-
2005
- 2005-11-15 US US11/273,372 patent/US7259265B2/en not_active Expired - Fee Related
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