JP2007277579A5 - - Google Patents

Info

Publication number

JP2007277579A5

JP2007277579A5 JP2007181599A JP2007181599A JP2007277579A5 JP 2007277579 A5 JP2007277579 A5 JP 2007277579A5 JP 2007181599 A JP2007181599 A JP 2007181599A JP 2007181599 A JP2007181599 A JP 2007181599A JP 2007277579 A5 JP2007277579 A5 JP 2007277579A5

Authority

JP

Japan

Prior art keywords

product

bioabsorbable polymer

polyanionic polysaccharide

hydrophobic

hydrophobic bioabsorbable

Prior art date

2007-07-11

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• 150000004676 glycans Chemical class 0.000 claims 17
• 229920001282 polysaccharide Polymers 0.000 claims 17
• 239000005017 polysaccharide Substances 0.000 claims 17
• 230000002209 hydrophobic effect Effects 0.000 claims 16
• 229920000642 polymer Polymers 0.000 claims 15
• 238000000034 method Methods 0.000 claims 10
• 210000004027 cell Anatomy 0.000 claims 8
• 239000011248 coating agent Substances 0.000 claims 6
• 238000000576 coating method Methods 0.000 claims 6
• 239000000203 mixture Substances 0.000 claims 6
• AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 4
• 229920000954 Polyglycolide Polymers 0.000 claims 4
• 229920000747 poly(lactic acid) Polymers 0.000 claims 4
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 3
• 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 3
• 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 3
• 239000001768 carboxy methyl cellulose Substances 0.000 claims 3
• 239000008112 carboxymethyl-cellulose Substances 0.000 claims 3
• 229940079593 drug Drugs 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 3
• 239000000835 fiber Substances 0.000 claims 3
• 229920002674 hyaluronan Polymers 0.000 claims 3
• 229960003160 hyaluronic acid Drugs 0.000 claims 3
• 238000000465 moulding Methods 0.000 claims 3
• HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 2
• 241000124008 Mammalia Species 0.000 claims 2
• 230000003115 biocidal effect Effects 0.000 claims 2
• -1 carboxymethylamylose Polymers 0.000 claims 2
• 229920001577 copolymer Polymers 0.000 claims 2
• 239000006260 foam Substances 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 229920001610 polycaprolactone Polymers 0.000 claims 2
• 239000004632 polycaprolactone Substances 0.000 claims 2
• 229920000856 Amylose Polymers 0.000 claims 1
• 229920001287 Chondroitin sulfate Polymers 0.000 claims 1
• 229920000045 Dermatan sulfate Polymers 0.000 claims 1
• 229920002971 Heparan sulfate Polymers 0.000 claims 1
• 108091034117 Oligonucleotide Proteins 0.000 claims 1
• 125000003368 amide group Chemical group 0.000 claims 1
• 125000003277 amino group Chemical group 0.000 claims 1
• 229920001222 biopolymer Polymers 0.000 claims 1
• 210000002449 bone cell Anatomy 0.000 claims 1
• 150000004649 carbonic acid derivatives Chemical class 0.000 claims 1
• 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
• 238000006243 chemical reaction Methods 0.000 claims 1
• 239000003795 chemical substances by application Substances 0.000 claims 1
• 210000001612 chondrocyte Anatomy 0.000 claims 1
• 239000003145 cytotoxic factor Substances 0.000 claims 1
• AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 claims 1
• 229940051593 dermatan sulfate Drugs 0.000 claims 1
• 125000004185 ester group Chemical group 0.000 claims 1
• 210000002950 fibroblast Anatomy 0.000 claims 1
• 239000003102 growth factor Substances 0.000 claims 1
• 229920000669 heparin Polymers 0.000 claims 1
• 229960002897 heparin Drugs 0.000 claims 1
• 210000002510 keratinocyte Anatomy 0.000 claims 1
• 239000012528 membrane Substances 0.000 claims 1
• 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
• 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
• 229920002463 poly(p-dioxanone) polymer Polymers 0.000 claims 1
• 239000000622 polydioxanone Substances 0.000 claims 1
• 229920000728 polyester Polymers 0.000 claims 1
• 229920005594 polymer fiber Polymers 0.000 claims 1
• 102000004169 proteins and genes Human genes 0.000 claims 1
• 108090000623 proteins and genes Proteins 0.000 claims 1
• 238000005507 spraying Methods 0.000 claims 1
• 150000003431 steroids Chemical class 0.000 claims 1
• 210000002435 tendon Anatomy 0.000 claims 1