JP2007137778A5 - - Google Patents
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- Publication number
- JP2007137778A5 JP2007137778A5 JP2005329591A JP2005329591A JP2007137778A5 JP 2007137778 A5 JP2007137778 A5 JP 2007137778A5 JP 2005329591 A JP2005329591 A JP 2005329591A JP 2005329591 A JP2005329591 A JP 2005329591A JP 2007137778 A5 JP2007137778 A5 JP 2007137778A5
- Authority
- JP
- Japan
- Prior art keywords
- cell membrane
- density lipoprotein
- somatic cell
- food
- somatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N (3β)-Cholest-5-en-3-ol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 44
- 239000012528 membrane Substances 0.000 claims description 36
- 210000001082 somatic cell Anatomy 0.000 claims description 36
- 235000013305 food Nutrition 0.000 claims description 23
- 229940107161 Cholesterol Drugs 0.000 claims description 22
- 102000000853 LDL receptors Human genes 0.000 claims description 22
- 108010001831 LDL receptors Proteins 0.000 claims description 22
- 210000004369 Blood Anatomy 0.000 claims description 15
- 239000008280 blood Substances 0.000 claims description 15
- 229940109850 royal jelly Drugs 0.000 claims description 15
- 230000002708 enhancing Effects 0.000 claims description 12
- 238000005728 strengthening Methods 0.000 claims description 11
- 102000004169 proteins and genes Human genes 0.000 claims description 8
- 108090000623 proteins and genes Proteins 0.000 claims description 8
- 239000004480 active ingredient Substances 0.000 claims description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 3
- 235000012000 cholesterol Nutrition 0.000 description 20
- 230000001737 promoting Effects 0.000 description 11
- 102000007330 LDL Lipoproteins Human genes 0.000 description 9
- 108010007622 LDL Lipoproteins Proteins 0.000 description 9
- 230000000392 somatic Effects 0.000 description 9
- 210000004027 cells Anatomy 0.000 description 8
- 210000000170 Cell Membrane Anatomy 0.000 description 7
- 239000003795 chemical substances by application Substances 0.000 description 6
- 101700048880 MRJP1 Proteins 0.000 description 5
- 210000002381 Plasma Anatomy 0.000 description 4
- 239000002775 capsule Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 102000003886 Glycoproteins Human genes 0.000 description 2
- 108090000288 Glycoproteins Proteins 0.000 description 2
- 241000257303 Hymenoptera Species 0.000 description 2
- 206010062060 Hyperlipidaemia Diseases 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 229940079593 drugs Drugs 0.000 description 2
- 235000006694 eating habits Nutrition 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000001766 physiological effect Effects 0.000 description 2
- 230000003014 reinforcing Effects 0.000 description 2
- OCYROESYHWUPBP-VGMNWLOBSA-N (2S,3R)-3-methyl-2-[[(2S)-pyrrolidin-1-ium-2-carbonyl]amino]pentanoate Chemical compound CC[C@@H](C)[C@@H](C(O)=O)NC(=O)[C@@H]1CCCN1 OCYROESYHWUPBP-VGMNWLOBSA-N 0.000 description 1
- 241000256844 Apis mellifera Species 0.000 description 1
- NALWOULWGHTVDA-UWVGGRQHSA-N Asp-Tyr Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 NALWOULWGHTVDA-UWVGGRQHSA-N 0.000 description 1
- MQLZLIYPFDIDMZ-UHFFFAOYSA-N Asparaginyl-Isoleucine Chemical group CCC(C)C(C(O)=O)NC(=O)C(N)CC(N)=O MQLZLIYPFDIDMZ-UHFFFAOYSA-N 0.000 description 1
- SXGAGTVDWKQYCX-BQBZGAKWSA-N Glu-Met Chemical compound CSCC[C@@H](C(O)=O)NC(=O)[C@@H](N)CCC(O)=O SXGAGTVDWKQYCX-BQBZGAKWSA-N 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- XWOBNBRUDDUEEY-UWVGGRQHSA-N Leu-His Chemical compound CC(C)C[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CNC=N1 XWOBNBRUDDUEEY-UWVGGRQHSA-N 0.000 description 1
- OTXBNHIUIHNGAO-UWVGGRQHSA-N Leu-Lys Chemical compound CC(C)C[C@H](N)C(=O)N[C@H](C(O)=O)CCCCN OTXBNHIUIHNGAO-UWVGGRQHSA-N 0.000 description 1
- ATIPDCIQTUXABX-UWVGGRQHSA-N Lys-Leu Chemical compound CC(C)C[C@@H](C(O)=O)NC(=O)[C@@H](N)CCCCN ATIPDCIQTUXABX-UWVGGRQHSA-N 0.000 description 1
- QCZYYEFXOBKCNQ-STQMWFEESA-N Lys-Phe Chemical compound NCCCC[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 QCZYYEFXOBKCNQ-STQMWFEESA-N 0.000 description 1
- 102000005741 Metalloproteases Human genes 0.000 description 1
- 108010006035 Metalloproteases Proteins 0.000 description 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 description 1
- 108010052388 RGES peptide Proteins 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive Effects 0.000 description 1
- 230000001058 adult Effects 0.000 description 1
- 108010068265 aspartyltyrosine Proteins 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000037348 biosynthesis Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 235000014510 cooky Nutrition 0.000 description 1
- 235000012495 crackers Nutrition 0.000 description 1
- 230000004059 degradation Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 108010079547 glutamylmethionine Proteins 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 108010034529 leucyl-lysine Proteins 0.000 description 1
- 108010057821 leucylproline Proteins 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 108010038320 lysylphenylalanine Proteins 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002250 progressing Effects 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005329591A JP2007137778A (ja) | 2005-11-15 | 2005-11-15 | 低密度リポタンパク受容体の発現促進剤及びそれを含有する食品 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005329591A JP2007137778A (ja) | 2005-11-15 | 2005-11-15 | 低密度リポタンパク受容体の発現促進剤及びそれを含有する食品 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007137778A JP2007137778A (ja) | 2007-06-07 |
| JP2007137778A5 true JP2007137778A5 (sv) | 2008-11-13 |
Family
ID=38201094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005329591A Pending JP2007137778A (ja) | 2005-11-15 | 2005-11-15 | 低密度リポタンパク受容体の発現促進剤及びそれを含有する食品 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2007137778A (sv) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5329064B2 (ja) * | 2007-09-03 | 2013-10-30 | 株式会社クヰンビーガーデン | 抗コレステロール剤 |
| JP2012106988A (ja) * | 2010-10-26 | 2012-06-07 | Akitaya Honten:Kk | 胆汁酸結合剤、血清コレステロール量低下剤、及び血清コレステロール量を低下させる方法 |
| JP2013091606A (ja) * | 2011-10-24 | 2013-05-16 | Akitaya Honten:Kk | 血清コレステロール量低下剤、及び血清コレステロール量を低下させる方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001172190A (ja) * | 1999-12-15 | 2001-06-26 | Pola Chem Ind Inc | 乳酸蓄積抑制剤 |
| JP2001240549A (ja) * | 2000-03-01 | 2001-09-04 | Pola Chem Ind Inc | 免疫増強剤及びそれを含有してなる組成物 |
| JP2003000163A (ja) * | 2001-06-21 | 2003-01-07 | Pola Chem Ind Inc | ハイビスカスエキスを含有するローヤルゼリー組成物 |
| JP2003061649A (ja) * | 2001-08-29 | 2003-03-04 | Pola Chem Ind Inc | Ｍａｐキナーゼ活性化剤 |
| JP2003061648A (ja) * | 2001-08-29 | 2003-03-04 | Pola Chem Ind Inc | プロテインキナーゼｂ活性化剤 |
| JP2003219816A (ja) * | 2002-01-31 | 2003-08-05 | Kikuji Yamaguchi | ローヤルゼリーを含有する食品および薬剤 |
| JP3815726B2 (ja) * | 2002-02-01 | 2006-08-30 | ポーラ化成工業株式会社 | 緩衝液からなるローヤルゼリーの鮮度保持剤 |
-
2005
- 2005-11-15 JP JP2005329591A patent/JP2007137778A/ja active Pending
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