JP2006526638A - 眼圧降下剤としての３−オキサ−８−アザプロスタグランジン類似体 - Google Patents
眼圧降下剤としての３−オキサ−８−アザプロスタグランジン類似体 Download PDFInfo
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- JP2006526638A JP2006526638A JP2006514964A JP2006514964A JP2006526638A JP 2006526638 A JP2006526638 A JP 2006526638A JP 2006514964 A JP2006514964 A JP 2006514964A JP 2006514964 A JP2006514964 A JP 2006514964A JP 2006526638 A JP2006526638 A JP 2006526638A
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- 239000001103 potassium chloride Substances 0.000 description 1
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- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 description 1
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- NRTYMEPCRDJMPZ-UHFFFAOYSA-N pyridine;2,2,2-trifluoroacetic acid Chemical compound C1=CC=NC=C1.OC(=O)C(F)(F)F NRTYMEPCRDJMPZ-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/453,207 US6734206B1 (en) | 2003-06-02 | 2003-06-02 | 3-oxa-8-azaprostaglandin analogs as agents for lowering intraocular pressure |
| PCT/US2004/016516 WO2004108670A1 (en) | 2003-06-02 | 2004-05-25 | 3-oxa-8-azaprostaglandin analogs as agents for lowering intraocular pressure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006526638A true JP2006526638A (ja) | 2006-11-24 |
| JP2006526638A5 JP2006526638A5 (enExample) | 2007-07-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006514964A Pending JP2006526638A (ja) | 2003-06-02 | 2004-05-25 | 眼圧降下剤としての３−オキサ−８−アザプロスタグランジン類似体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6734206B1 (enExample) |
| EP (1) | EP1638936B1 (enExample) |
| JP (1) | JP2006526638A (enExample) |
| AT (1) | ATE496886T1 (enExample) |
| AU (1) | AU2004245492B2 (enExample) |
| BR (1) | BRPI0410926A (enExample) |
| CA (1) | CA2528010C (enExample) |
| DE (1) | DE602004031225D1 (enExample) |
| ES (1) | ES2358513T3 (enExample) |
| WO (1) | WO2004108670A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6734201B1 (en) * | 2003-06-02 | 2004-05-11 | Allergan, Inc. | 8-Azaprostaglandin carbonate and thiocarbonate analogs as therapeutic agents |
| EP2628725A1 (en) | 2005-11-03 | 2013-08-21 | Allergan, Inc. | Prostaglandins and analogues as agents for lowering intraocular pressure |
| US20110293549A1 (en) | 2009-02-03 | 2011-12-01 | Athena Cosmetics, Inc. | Composition, method and kit for enhancing hair |
| US8783923B2 (en) * | 2010-03-18 | 2014-07-22 | Chung Yuan Christian University | Auto lamp structure |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000038667A2 (en) * | 1998-12-24 | 2000-07-06 | Alcon Laboratories, Inc. | Prostaglandin e agonists for treatment of glaucoma |
| WO2002102389A1 (en) * | 2001-06-14 | 2002-12-27 | Allergan, Inc. | 3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| WO2003007941A1 (en) * | 2001-07-16 | 2003-01-30 | F. Hoffmann-La Roche Ag | 2 pyrrolidone derivatives as prostanoid agonists |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5028624A (en) | 1989-07-27 | 1991-07-02 | Allergan, Inc. | Intraocular pressure reducing 9,15-diacyl prostaglandins |
| CA2021316C (en) | 1989-07-27 | 2000-10-24 | Ming Fai Chan | Intraocular pressure reducing 11-acyl prostaglandins |
| US5034413A (en) | 1989-07-27 | 1991-07-23 | Allergan, Inc. | Intraocular pressure reducing 9,11-diacyl prostaglandins |
| US4994274A (en) | 1989-07-27 | 1991-02-19 | Allergan, Inc. | Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using |
| MXPA02006322A (es) * | 1999-12-22 | 2002-12-13 | Pfizer Prod Inc | Agonistas selectivos del receptor ep4 en el tratamiento de la osteoporosis. |
| ATE327751T1 (de) | 2000-01-31 | 2006-06-15 | Pfizer Prod Inc | Verwendung von aktivatoren des prostaglandinrezeptores 4 zur behandlung von akuter oder chronischer niereninsuffizienz |
| US20010056060A1 (en) | 2000-02-07 | 2001-12-27 | Cameron Kimberly O. | Treatment of osteoporsis with EP2/EP4 receptor selective agonists |
| JP4063468B2 (ja) | 2000-02-22 | 2008-03-19 | 株式会社カネボウ化粧品 | 寒天被覆処理顔料およびメイクアップ化粧料 |
| AU2001290250A1 (en) | 2000-09-21 | 2002-04-02 | Ono Pharmaceutical Co. Ltd. | Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient |
| MXPA03004623A (es) | 2000-11-27 | 2003-09-05 | Pfizer Prod Inc | Agonistas selectivos del receptor ep4 en el tratamiento de la osteoporosis. |
| MXPA04000456A (es) * | 2001-07-16 | 2004-03-18 | Hoffmann La Roche | Analogos de prostaglandina como agonistas del receptor ep4. |
| CA2454584C (en) | 2001-07-23 | 2009-09-22 | Ono Pharmaceutical Co., Ltd. | Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising ep4 agonist as active ingredient |
| CA2478653A1 (en) * | 2002-03-18 | 2003-09-25 | Pfizer Products Inc. | Methods of treatment with selective ep4 receptor agonists |
| AU2003209571A1 (en) * | 2002-03-18 | 2003-09-29 | Pfizer Products Inc. | Use of selective ep4 receptor agonists for the treatment of liver failure, loss of patency of the ductus arteriosus, glaucoma or ocular hypertension |
-
2003
- 2003-06-02 US US10/453,207 patent/US6734206B1/en not_active Expired - Fee Related
-
2004
- 2004-05-25 ES ES04753359T patent/ES2358513T3/es not_active Expired - Lifetime
- 2004-05-25 WO PCT/US2004/016516 patent/WO2004108670A1/en not_active Ceased
- 2004-05-25 CA CA2528010A patent/CA2528010C/en not_active Expired - Fee Related
- 2004-05-25 EP EP04753359A patent/EP1638936B1/en not_active Expired - Lifetime
- 2004-05-25 BR BRPI0410926-0A patent/BRPI0410926A/pt not_active IP Right Cessation
- 2004-05-25 DE DE602004031225T patent/DE602004031225D1/de not_active Expired - Lifetime
- 2004-05-25 AU AU2004245492A patent/AU2004245492B2/en not_active Ceased
- 2004-05-25 JP JP2006514964A patent/JP2006526638A/ja active Pending
- 2004-05-25 AT AT04753359T patent/ATE496886T1/de not_active IP Right Cessation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000038667A2 (en) * | 1998-12-24 | 2000-07-06 | Alcon Laboratories, Inc. | Prostaglandin e agonists for treatment of glaucoma |
| WO2002102389A1 (en) * | 2001-06-14 | 2002-12-27 | Allergan, Inc. | 3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| WO2003007941A1 (en) * | 2001-07-16 | 2003-01-30 | F. Hoffmann-La Roche Ag | 2 pyrrolidone derivatives as prostanoid agonists |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE496886T1 (de) | 2011-02-15 |
| WO2004108670A1 (en) | 2004-12-16 |
| BRPI0410926A (pt) | 2006-06-27 |
| ES2358513T3 (es) | 2011-05-11 |
| CA2528010C (en) | 2012-01-24 |
| AU2004245492A1 (en) | 2004-12-16 |
| US6734206B1 (en) | 2004-05-11 |
| EP1638936B1 (en) | 2011-01-26 |
| EP1638936A1 (en) | 2006-03-29 |
| AU2004245492B2 (en) | 2010-08-19 |
| DE602004031225D1 (de) | 2011-03-10 |
| CA2528010A1 (en) | 2004-12-16 |
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