JP2006526592A - 血管由来の欠損に関連する高コレステロール血症または糖尿病の治療のための、線維芽細胞成長因子をコードするプラスミド - Google Patents

血管由来の欠損に関連する高コレステロール血症または糖尿病の治療のための、線維芽細胞成長因子をコードするプラスミド Download PDF

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JP2006526592A
JP2006526592A JP2006508289A JP2006508289A JP2006526592A JP 2006526592 A JP2006526592 A JP 2006526592A JP 2006508289 A JP2006508289 A JP 2006508289A JP 2006508289 A JP2006508289 A JP 2006508289A JP 2006526592 A JP2006526592 A JP 2006526592A
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muscle
plasmid
hypercholesterolemia
ischemic
fgf
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JP2006526592A5 (enExample
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キャロン、アレクシス
エマニュエル、フローレンス
キャロン、アンネ
フィニエルス、フランソワーズ
ミシュレ、サンドリーヌ
シュワルツ、ベルトラン
ルイ、ディディエ
ブラヌレック、ディディエ
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Centelion SAS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006508289A 2003-06-05 2004-06-04 血管由来の欠損に関連する高コレステロール血症または糖尿病の治療のための、線維芽細胞成長因子をコードするプラスミド Pending JP2006526592A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US47595903P 2003-06-05 2003-06-05
US56091504P 2004-04-09 2004-04-09
US56619304P 2004-04-28 2004-04-28
PCT/EP2004/006903 WO2004108167A1 (en) 2003-06-05 2004-06-04 Plasmid encoding fibroblast growth factor for the treatment of hypercholesterolemia or diabetes associated angiogenic defects

Publications (2)

Publication Number Publication Date
JP2006526592A true JP2006526592A (ja) 2006-11-24
JP2006526592A5 JP2006526592A5 (enExample) 2007-05-17

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Family Applications (1)

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JP2006508289A Pending JP2006526592A (ja) 2003-06-05 2004-06-04 血管由来の欠損に関連する高コレステロール血症または糖尿病の治療のための、線維芽細胞成長因子をコードするプラスミド

Country Status (11)

Country Link
US (1) US20050096286A1 (enExample)
EP (1) EP1677831A1 (enExample)
JP (1) JP2006526592A (enExample)
KR (1) KR20060052692A (enExample)
AU (2) AU2004244756A1 (enExample)
BR (1) BRPI0410844A (enExample)
CA (1) CA2526792A1 (enExample)
EA (1) EA009390B1 (enExample)
NO (1) NO20060032L (enExample)
NZ (1) NZ543717A (enExample)
WO (1) WO2004108167A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536909A (ja) * 2003-12-29 2007-12-20 センテリオン 冠動脈または末梢性虚血の治療

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US7038026B2 (en) 2000-05-26 2006-05-02 Centelion Purification of a triple heli formation with an immobilized oligonucleotide
US7279313B2 (en) 1995-09-15 2007-10-09 Centelion Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy
FR2822476B1 (fr) 2001-03-23 2004-04-02 Aventis Pharma Sa Procedes de purification et de detection de sequences cibles d'adn double brin par interaction triple helice
AU2007212260A1 (en) * 2006-02-09 2007-08-16 Sangamo Therapeutics, Inc. Method for treating peripheral arterial disease with zinc finger proteins
MX2012004303A (es) * 2009-10-15 2012-06-25 Genentech Inc Factores de crecimiento de fibroblasto quimericos con especificacion de receptor alterada.
JP5767314B2 (ja) 2010-04-16 2015-08-19 ソーク インスティチュート フォー バイオロジカル スタディーズ Fgfを用いて代謝障害を処置するための方法
WO2015061331A1 (en) 2013-10-21 2015-04-30 Salk Institute For Biological Studies Chimeric fibroblast growth factor (fgf) 2/fgf1 peptides and methods of use
JP6621752B2 (ja) 2013-10-21 2019-12-18 ソーク インスティテュート フォー バイオロジカル スタディーズ 変異した線維芽細胞増殖因子(fgf)1および使用方法
EP3368059A4 (en) 2015-10-30 2019-03-27 Salk Institute for Biological Studies TREATMENT OF STEROID-INDUCED HYPERGLYCEMIA WITH FIBROBLAST GROWTH FACTOR (FGF) -1 ANALOGUE
US11542309B2 (en) 2019-07-31 2023-01-03 Salk Institute For Biological Studies Fibroblast growth factor 1 (FGF1) mutant proteins that selectively activate FGFR1B to reduce blood glucose
US11746352B2 (en) * 2019-12-30 2023-09-05 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread
US12098372B2 (en) 2019-12-30 2024-09-24 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread

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JPS6372652A (ja) * 1986-06-23 1988-04-02 メルク エンド カムパニ− インコ−ポレ−テツド 新規HMG−CoAレダクタ−ゼ阻害剤
JPH0348673A (ja) * 1989-06-23 1991-03-01 Merck & Co Inc 3―ケト、5―ヒドロキシシンバスタチンアナログの製造方法
US20020122792A1 (en) * 1998-07-24 2002-09-05 Thomas J. Stegmann Induction of neoangiogenesis in ischemic myocardium

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CA1136620A (en) * 1979-01-08 1982-11-30 Ulf P.F. Lindahl Heparin fragments having selective anticoagulation activity
IL72058A (en) * 1984-06-08 1988-03-31 Ram Lavie Method for heat and mass exchange operations
US5168062A (en) * 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4686113A (en) * 1985-12-18 1987-08-11 Fairchild Semiconductor Corporation Plasma confinement in a low pressure electrically grounded R.F. heated reactor and deposition method
US5827826A (en) * 1986-03-03 1998-10-27 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compositions of human endothelial cell growth factor
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US5045565A (en) * 1987-03-09 1991-09-03 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
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US5733871A (en) * 1991-11-08 1998-03-31 The General Hospital Corporation Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration
US6121246A (en) * 1995-10-20 2000-09-19 St. Elizabeth's Medical Center Of Boston, Inc. Method for treating ischemic tissue
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WO1999001150A1 (en) * 1997-07-03 1999-01-14 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Novel composition for treating, preventing and/or delaying ischemic cell death
DE69838526T2 (de) * 1998-02-05 2008-07-03 Biosense Webster, Inc., Diamond Bar Gerät zum Freisetzen eines Medikaments im Herzen
US6642026B2 (en) * 2000-08-15 2003-11-04 Phage Biotechnology Corporation Method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis
US6102887A (en) * 1998-08-11 2000-08-15 Biocardia, Inc. Catheter drug delivery system and method for use
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JPS6372652A (ja) * 1986-06-23 1988-04-02 メルク エンド カムパニ− インコ−ポレ−テツド 新規HMG−CoAレダクタ−ゼ阻害剤
JPH0348673A (ja) * 1989-06-23 1991-03-01 Merck & Co Inc 3―ケト、5―ヒドロキシシンバスタチンアナログの製造方法
US20020122792A1 (en) * 1998-07-24 2002-09-05 Thomas J. Stegmann Induction of neoangiogenesis in ischemic myocardium

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536909A (ja) * 2003-12-29 2007-12-20 センテリオン 冠動脈または末梢性虚血の治療

Also Published As

Publication number Publication date
EP1677831A1 (en) 2006-07-12
KR20060052692A (ko) 2006-05-19
NO20060032L (no) 2006-01-04
BRPI0410844A (pt) 2006-06-27
AU2004244756A1 (en) 2004-12-16
CA2526792A1 (en) 2004-12-16
NZ543717A (en) 2008-06-30
US20050096286A1 (en) 2005-05-05
WO2004108167A1 (en) 2004-12-16
EA200501846A1 (ru) 2007-12-28
EA009390B1 (ru) 2007-12-28
AU2010257389A1 (en) 2011-01-27

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