NO20060032L - Plasmid som koder for fibroblastvekstfaktor for behandling av hyperkolesterolemi eller diabetesrelaterte angiogeniske defekter - Google Patents

Plasmid som koder for fibroblastvekstfaktor for behandling av hyperkolesterolemi eller diabetesrelaterte angiogeniske defekter

Info

Publication number
NO20060032L
NO20060032L NO20060032A NO20060032A NO20060032L NO 20060032 L NO20060032 L NO 20060032L NO 20060032 A NO20060032 A NO 20060032A NO 20060032 A NO20060032 A NO 20060032A NO 20060032 L NO20060032 L NO 20060032L
Authority
NO
Norway
Prior art keywords
growth factor
hypercholesterolemia
diabetes
fibroblast growth
treatment
Prior art date
Application number
NO20060032A
Other languages
English (en)
Inventor
Alexis Caron
Florence Emmanuel
Anne Caron
Francoise Finiels
Sandrine Michelet
Bertrand Schwartz
Didier Rouy
Didier Branellec
Original Assignee
Centelion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centelion filed Critical Centelion
Publication of NO20060032L publication Critical patent/NO20060032L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Sammendrag Denne oppfinnelsen gjelder bruken av et plasmid som koder for en vekstfaktor for fibroblast (heretter kalt "fibroblastvekstfaktor") som terapeutisk middel for forebygging og behandling av hyperkolesterolemi eller diabetes forbundet med angiogeniske defekter i myokardium eller skjelett. Denne oppfinnelsen gjelder også en metode for å forbedre dannelsen av både kollaterale blodkar og arterioler i de iskemiske vevene i myokardium eller skjelettet på et pattedyr som lider av hyperkolesterolemi eller diabetes. Denne oppfinnelsen gjelder også en fremgangsmåte for å fremme dannelsen av kollaterale blodkar i iskemiske vev i myokardium eller skjelettet uten å utløse VEGF-A-faktorekspresjon (vascular endothelial growth factor) og forårsake ødem i de behandlede musklene.
NO20060032A 2003-06-05 2006-01-04 Plasmid som koder for fibroblastvekstfaktor for behandling av hyperkolesterolemi eller diabetesrelaterte angiogeniske defekter NO20060032L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US47595903P 2003-06-05 2003-06-05
US56091504P 2004-04-09 2004-04-09
US56619304P 2004-04-28 2004-04-28
PCT/EP2004/006903 WO2004108167A1 (en) 2003-06-05 2004-06-04 Plasmid encoding fibroblast growth factor for the treatment of hypercholesterolemia or diabetes associated angiogenic defects

Publications (1)

Publication Number Publication Date
NO20060032L true NO20060032L (no) 2006-01-04

Family

ID=33514717

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060032A NO20060032L (no) 2003-06-05 2006-01-04 Plasmid som koder for fibroblastvekstfaktor for behandling av hyperkolesterolemi eller diabetesrelaterte angiogeniske defekter

Country Status (11)

Country Link
US (1) US20050096286A1 (no)
EP (1) EP1677831A1 (no)
JP (1) JP2006526592A (no)
KR (1) KR20060052692A (no)
AU (2) AU2004244756A1 (no)
BR (1) BRPI0410844A (no)
CA (1) CA2526792A1 (no)
EA (1) EA200501846A1 (no)
NO (1) NO20060032L (no)
NZ (1) NZ543717A (no)
WO (1) WO2004108167A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7038026B2 (en) 2000-05-26 2006-05-02 Centelion Purification of a triple heli formation with an immobilized oligonucleotide
US7279313B2 (en) 1995-09-15 2007-10-09 Centelion Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy
FR2822476B1 (fr) 2001-03-23 2004-04-02 Aventis Pharma Sa Procedes de purification et de detection de sequences cibles d'adn double brin par interaction triple helice
MXPA06007519A (es) * 2003-12-29 2007-05-23 Centelion Tratamiento de la isquemia coronaria o periferica.
AU2007212260A1 (en) * 2006-02-09 2007-08-16 Sangamo Therapeutics, Inc. Method for treating peripheral arterial disease with zinc finger proteins
RU2573896C2 (ru) * 2009-10-15 2016-01-27 Дженентек, Инк. Химерные факторы роста фибробластов с измененной рецепторной специфичностью
EP2558115B1 (en) * 2010-04-16 2019-07-31 The Salk Institute for Biological Studies Methods for treating metabolic disorders using fgf
US9925241B2 (en) 2013-10-21 2018-03-27 Salk Institute For Biological Studies Mutated fibroblast growth factor (FGF) 1 and methods of use
WO2015061331A1 (en) 2013-10-21 2015-04-30 Salk Institute For Biological Studies Chimeric fibroblast growth factor (fgf) 2/fgf1 peptides and methods of use
JP2018535964A (ja) 2015-10-30 2018-12-06 ソーク インスティテュート フォー バイオロジカル スタディーズ 線維芽細胞増殖因子（ｆｇｆ）１アナログによるステロイド誘導性高血糖の処置
US11542309B2 (en) 2019-07-31 2023-01-03 Salk Institute For Biological Studies Fibroblast growth factor 1 (FGF1) mutant proteins that selectively activate FGFR1B to reduce blood glucose
US11746352B2 (en) * 2019-12-30 2023-09-05 Eligo Bioscience Microbiome modulation of a host by delivery of DNA payloads with minimized spread

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CA1136620A (en) * 1979-01-08 1982-11-30 Ulf P.F. Lindahl Heparin fragments having selective anticoagulation activity
IL72058A (en) * 1984-06-08 1988-03-31 Ram Lavie Method for heat and mass exchange operations
US5168062A (en) * 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4686113A (en) * 1985-12-18 1987-08-11 Fairchild Semiconductor Corporation Plasma confinement in a low pressure electrically grounded R.F. heated reactor and deposition method
US5827826A (en) * 1986-03-03 1998-10-27 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compositions of human endothelial cell growth factor
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Also Published As

Publication number Publication date
US20050096286A1 (en) 2005-05-05
BRPI0410844A (pt) 2006-06-27
AU2010257389A1 (en) 2011-01-27
EP1677831A1 (en) 2006-07-12
CA2526792A1 (en) 2004-12-16
NZ543717A (en) 2008-06-30
JP2006526592A (ja) 2006-11-24
AU2004244756A1 (en) 2004-12-16
KR20060052692A (ko) 2006-05-19
EA009390B1 (ru) 2007-12-28
WO2004108167A1 (en) 2004-12-16
EA200501846A1 (ru) 2007-12-28

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