BRPI0410844A - fator de crescimento de fibroblasto de codificação de plasmìdeo para o tratamento de defeitos angiogênicos associados com hipercolesterolemia ou diabetes - Google Patents
fator de crescimento de fibroblasto de codificação de plasmìdeo para o tratamento de defeitos angiogênicos associados com hipercolesterolemia ou diabetesInfo
- Publication number
- BRPI0410844A BRPI0410844A BRPI0410844-2A BRPI0410844A BRPI0410844A BR PI0410844 A BRPI0410844 A BR PI0410844A BR PI0410844 A BRPI0410844 A BR PI0410844A BR PI0410844 A BRPI0410844 A BR PI0410844A
- Authority
- BR
- Brazil
- Prior art keywords
- diabetes
- treatment
- growth factor
- fibroblast growth
- skeletal
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 5
- 208000035150 Hypercholesterolemia Diseases 0.000 title abstract 4
- 102000018233 Fibroblast Growth Factor Human genes 0.000 title abstract 3
- 108050007372 Fibroblast Growth Factor Proteins 0.000 title abstract 3
- 230000002491 angiogenic effect Effects 0.000 title abstract 3
- 230000007547 defect Effects 0.000 title abstract 3
- 229940126864 fibroblast growth factor Drugs 0.000 title abstract 3
- 239000013612 plasmid Substances 0.000 title abstract 3
- 230000002107 myocardial effect Effects 0.000 abstract 3
- 210000004204 blood vessel Anatomy 0.000 abstract 2
- 230000000302 ischemic effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- 206010030113 Oedema Diseases 0.000 abstract 1
- 102000009524 Vascular Endothelial Growth Factor A Human genes 0.000 abstract 1
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 abstract 1
- 239000002870 angiogenesis inducing agent Substances 0.000 abstract 1
- 210000001367 artery Anatomy 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 210000004165 myocardium Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 210000002027 skeletal muscle Anatomy 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47595903P | 2003-06-05 | 2003-06-05 | |
| US56091504P | 2004-04-09 | 2004-04-09 | |
| US56619304P | 2004-04-28 | 2004-04-28 | |
| PCT/EP2004/006903 WO2004108167A1 (en) | 2003-06-05 | 2004-06-04 | Plasmid encoding fibroblast growth factor for the treatment of hypercholesterolemia or diabetes associated angiogenic defects |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0410844A true BRPI0410844A (pt) | 2006-06-27 |
Family
ID=33514717
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410844-2A BRPI0410844A (pt) | 2003-06-05 | 2004-06-04 | fator de crescimento de fibroblasto de codificação de plasmìdeo para o tratamento de defeitos angiogênicos associados com hipercolesterolemia ou diabetes |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20050096286A1 (enExample) |
| EP (1) | EP1677831A1 (enExample) |
| JP (1) | JP2006526592A (enExample) |
| KR (1) | KR20060052692A (enExample) |
| AU (2) | AU2004244756A1 (enExample) |
| BR (1) | BRPI0410844A (enExample) |
| CA (1) | CA2526792A1 (enExample) |
| EA (1) | EA200501846A1 (enExample) |
| NO (1) | NO20060032L (enExample) |
| NZ (1) | NZ543717A (enExample) |
| WO (1) | WO2004108167A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7038026B2 (en) | 2000-05-26 | 2006-05-02 | Centelion | Purification of a triple heli formation with an immobilized oligonucleotide |
| US7279313B2 (en) | 1995-09-15 | 2007-10-09 | Centelion | Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy |
| FR2822476B1 (fr) | 2001-03-23 | 2004-04-02 | Aventis Pharma Sa | Procedes de purification et de detection de sequences cibles d'adn double brin par interaction triple helice |
| EP1699819A2 (en) * | 2003-12-29 | 2006-09-13 | Centelion | Treatment of coronary or peripheral ischemia |
| CA2641198A1 (en) * | 2006-02-09 | 2007-08-16 | Sangamo Biosciences, Inc. | Method for treating peripheral arterial disease with zinc finger proteins |
| MX368790B (es) * | 2009-10-15 | 2019-10-16 | Genentech Inc | Factores de crecimiento de fibroblasto quimericos con especificidad de receptor alterada. |
| JP5767314B2 (ja) | 2010-04-16 | 2015-08-19 | ソーク インスティチュート フォー バイオロジカル スタディーズ | Fgfを用いて代謝障害を処置するための方法 |
| WO2015061331A1 (en) | 2013-10-21 | 2015-04-30 | Salk Institute For Biological Studies | Chimeric fibroblast growth factor (fgf) 2/fgf1 peptides and methods of use |
| CN105828833A (zh) | 2013-10-21 | 2016-08-03 | 萨克生物研究学院 | 突变的成纤维细胞生长因子(fgf)1及使用方法 |
| CA3002400A1 (en) | 2015-10-30 | 2017-05-04 | Salk Institute For Biological Studies | Treatment of steroid-induced hyperglycemia with fibroblast growth factor (fgf) 1 analogs |
| US11542309B2 (en) | 2019-07-31 | 2023-01-03 | Salk Institute For Biological Studies | Fibroblast growth factor 1 (FGF1) mutant proteins that selectively activate FGFR1B to reduce blood glucose |
| US11746352B2 (en) * | 2019-12-30 | 2023-09-05 | Eligo Bioscience | Microbiome modulation of a host by delivery of DNA payloads with minimized spread |
| US12098372B2 (en) | 2019-12-30 | 2024-09-24 | Eligo Bioscience | Microbiome modulation of a host by delivery of DNA payloads with minimized spread |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4692435A (en) * | 1978-11-06 | 1987-09-08 | Choay, S.A. | Mucopolysaccharide composition having a regulatory action on coagulation, medicament containing same and process of preparation |
| CA1136620A (en) * | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
| IL72058A (en) * | 1984-06-08 | 1988-03-31 | Ram Lavie | Method for heat and mass exchange operations |
| US5168062A (en) * | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4686113A (en) * | 1985-12-18 | 1987-08-11 | Fairchild Semiconductor Corporation | Plasma confinement in a low pressure electrically grounded R.F. heated reactor and deposition method |
| US5827826A (en) * | 1986-03-03 | 1998-10-27 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compositions of human endothelial cell growth factor |
| ZA874487B (en) * | 1986-06-23 | 1987-12-23 | Merck & Co.,Inc. | Novel hmg-coa reductase inhibitors |
| CA1322163C (en) * | 1986-07-03 | 1993-09-14 | Kenneth A. Thomas, Jr. | Plasminogen activator production |
| US5045565A (en) * | 1987-03-09 | 1991-09-03 | The Procter & Gamble Company | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain |
| US4965200A (en) * | 1989-06-23 | 1990-10-23 | Merck & Co., Inc. | Process for the preparation of 3-keto, 5-hydroxy simvastatin analogs |
| FR2663639B1 (fr) * | 1990-06-26 | 1994-03-18 | Rhone Poulenc Sante | Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation. |
| WO1993008828A1 (en) * | 1991-11-08 | 1993-05-13 | Syntex-Synergen Neuroscience Joint Venture | Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration |
| US6121246A (en) * | 1995-10-20 | 2000-09-19 | St. Elizabeth's Medical Center Of Boston, Inc. | Method for treating ischemic tissue |
| US6086582A (en) * | 1997-03-13 | 2000-07-11 | Altman; Peter A. | Cardiac drug delivery system |
| AU8855798A (en) * | 1997-07-03 | 1999-01-25 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Novel composition for treating, preventing and/or delaying ischemic cell death |
| EP1563866B1 (en) * | 1998-02-05 | 2007-10-03 | Biosense Webster, Inc. | Intracardiac drug delivery |
| US20020122792A1 (en) * | 1998-07-24 | 2002-09-05 | Thomas J. Stegmann | Induction of neoangiogenesis in ischemic myocardium |
| US6102887A (en) * | 1998-08-11 | 2000-08-15 | Biocardia, Inc. | Catheter drug delivery system and method for use |
| US20010034023A1 (en) * | 1999-04-26 | 2001-10-25 | Stanton Vincent P. | Gene sequence variations with utility in determining the treatment of disease, in genes relating to drug processing |
| US20020037508A1 (en) * | 2000-01-19 | 2002-03-28 | Michele Cargill | Human single nucleotide polymorphisms |
| US6988004B2 (en) * | 2000-05-16 | 2006-01-17 | Bioheart, Inc. | Method for inducing angiogenesis by electrical stimulation of muscles |
| JP2004517607A (ja) * | 2000-08-15 | 2004-06-17 | ファージ バイオテクノロジー コーポレイション | 生物学的に活性なヒト酸性線維芽細胞成長因子の産生方法および血管新生の促進におけるその使用 |
| AU2640002A (en) * | 2000-12-07 | 2002-06-18 | Aventis Pharma Sa | Sequences upstream of the carp gene, vectors containing them and uses thereof |
-
2004
- 2004-06-04 EP EP04740314A patent/EP1677831A1/en not_active Withdrawn
- 2004-06-04 WO PCT/EP2004/006903 patent/WO2004108167A1/en not_active Ceased
- 2004-06-04 KR KR1020057023058A patent/KR20060052692A/ko not_active Ceased
- 2004-06-04 AU AU2004244756A patent/AU2004244756A1/en not_active Abandoned
- 2004-06-04 BR BRPI0410844-2A patent/BRPI0410844A/pt not_active IP Right Cessation
- 2004-06-04 EA EA200501846A patent/EA200501846A1/ru not_active IP Right Cessation
- 2004-06-04 JP JP2006508289A patent/JP2006526592A/ja active Pending
- 2004-06-04 NZ NZ543717A patent/NZ543717A/en unknown
- 2004-06-04 CA CA002526792A patent/CA2526792A1/en not_active Abandoned
- 2004-06-07 US US10/861,906 patent/US20050096286A1/en not_active Abandoned
-
2006
- 2006-01-04 NO NO20060032A patent/NO20060032L/no not_active Application Discontinuation
-
2010
- 2010-12-22 AU AU2010257389A patent/AU2010257389A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NO20060032L (no) | 2006-01-04 |
| AU2010257389A1 (en) | 2011-01-27 |
| WO2004108167A1 (en) | 2004-12-16 |
| EA009390B1 (ru) | 2007-12-28 |
| JP2006526592A (ja) | 2006-11-24 |
| KR20060052692A (ko) | 2006-05-19 |
| EA200501846A1 (ru) | 2007-12-28 |
| US20050096286A1 (en) | 2005-05-05 |
| AU2004244756A1 (en) | 2004-12-16 |
| EP1677831A1 (en) | 2006-07-12 |
| CA2526792A1 (en) | 2004-12-16 |
| NZ543717A (en) | 2008-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |