EA009390B1 - Плазмида, кодирующая фактор роста фибробластов, для лечения ангиогенных дефектов, ассоциированных с гиперхолестеринемией или диабетом - Google Patents
Плазмида, кодирующая фактор роста фибробластов, для лечения ангиогенных дефектов, ассоциированных с гиперхолестеринемией или диабетом Download PDFInfo
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- EA009390B1 EA009390B1 EA200501846A EA200501846A EA009390B1 EA 009390 B1 EA009390 B1 EA 009390B1 EA 200501846 A EA200501846 A EA 200501846A EA 200501846 A EA200501846 A EA 200501846A EA 009390 B1 EA009390 B1 EA 009390B1
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- ischemic
- plasmid
- hypercholesterolemia
- ece
- myocardial
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
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- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US56091504P | 2004-04-09 | 2004-04-09 | |
| US56619304P | 2004-04-28 | 2004-04-28 | |
| PCT/EP2004/006903 WO2004108167A1 (en) | 2003-06-05 | 2004-06-04 | Plasmid encoding fibroblast growth factor for the treatment of hypercholesterolemia or diabetes associated angiogenic defects |
Publications (2)
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| EA200501846A1 EA200501846A1 (ru) | 2007-12-28 |
| EA009390B1 true EA009390B1 (ru) | 2007-12-28 |
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| EA200501846A EA009390B1 (ru) | 2003-06-05 | 2004-06-04 | Плазмида, кодирующая фактор роста фибробластов, для лечения ангиогенных дефектов, ассоциированных с гиперхолестеринемией или диабетом |
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| EP (1) | EP1677831A1 (enExample) |
| JP (1) | JP2006526592A (enExample) |
| KR (1) | KR20060052692A (enExample) |
| AU (2) | AU2004244756A1 (enExample) |
| BR (1) | BRPI0410844A (enExample) |
| CA (1) | CA2526792A1 (enExample) |
| EA (1) | EA009390B1 (enExample) |
| NO (1) | NO20060032L (enExample) |
| NZ (1) | NZ543717A (enExample) |
| WO (1) | WO2004108167A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7038026B2 (en) | 2000-05-26 | 2006-05-02 | Centelion | Purification of a triple heli formation with an immobilized oligonucleotide |
| US7279313B2 (en) | 1995-09-15 | 2007-10-09 | Centelion | Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy |
| FR2822476B1 (fr) | 2001-03-23 | 2004-04-02 | Aventis Pharma Sa | Procedes de purification et de detection de sequences cibles d'adn double brin par interaction triple helice |
| EP1699819A2 (en) * | 2003-12-29 | 2006-09-13 | Centelion | Treatment of coronary or peripheral ischemia |
| AU2007212260A1 (en) * | 2006-02-09 | 2007-08-16 | Sangamo Therapeutics, Inc. | Method for treating peripheral arterial disease with zinc finger proteins |
| MX2012004303A (es) * | 2009-10-15 | 2012-06-25 | Genentech Inc | Factores de crecimiento de fibroblasto quimericos con especificacion de receptor alterada. |
| JP5767314B2 (ja) | 2010-04-16 | 2015-08-19 | ソーク インスティチュート フォー バイオロジカル スタディーズ | Ｆｇｆを用いて代謝障害を処置するための方法 |
| WO2015061331A1 (en) | 2013-10-21 | 2015-04-30 | Salk Institute For Biological Studies | Chimeric fibroblast growth factor (fgf) 2/fgf1 peptides and methods of use |
| JP6621752B2 (ja) | 2013-10-21 | 2019-12-18 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 変異した線維芽細胞増殖因子（ｆｇｆ）１および使用方法 |
| EP3368059A4 (en) | 2015-10-30 | 2019-03-27 | Salk Institute for Biological Studies | TREATMENT OF STEROID-INDUCED HYPERGLYCEMIA WITH FIBROBLAST GROWTH FACTOR (FGF) -1 ANALOGUE |
| US11542309B2 (en) | 2019-07-31 | 2023-01-03 | Salk Institute For Biological Studies | Fibroblast growth factor 1 (FGF1) mutant proteins that selectively activate FGFR1B to reduce blood glucose |
| US11746352B2 (en) * | 2019-12-30 | 2023-09-05 | Eligo Bioscience | Microbiome modulation of a host by delivery of DNA payloads with minimized spread |
| US12098372B2 (en) | 2019-12-30 | 2024-09-24 | Eligo Bioscience | Microbiome modulation of a host by delivery of DNA payloads with minimized spread |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002014471A2 (en) * | 2000-08-15 | 2002-02-21 | Phage Biotechnology Corporation | A method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis |
| RU2000129133A (ru) * | 1998-04-17 | 2002-10-20 | Анджиодженикс, Инкорпорейтед | Терапевтические ангиогенные факторы и способы их применения |
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| US4692435A (en) * | 1978-11-06 | 1987-09-08 | Choay, S.A. | Mucopolysaccharide composition having a regulatory action on coagulation, medicament containing same and process of preparation |
| CA1136620A (en) * | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
| IL72058A (en) * | 1984-06-08 | 1988-03-31 | Ram Lavie | Method for heat and mass exchange operations |
| US5168062A (en) * | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4686113A (en) * | 1985-12-18 | 1987-08-11 | Fairchild Semiconductor Corporation | Plasma confinement in a low pressure electrically grounded R.F. heated reactor and deposition method |
| US5827826A (en) * | 1986-03-03 | 1998-10-27 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compositions of human endothelial cell growth factor |
| ZA874487B (en) * | 1986-06-23 | 1987-12-23 | Merck & Co.,Inc. | Novel hmg-coa reductase inhibitors |
| CA1322163C (en) * | 1986-07-03 | 1993-09-14 | Kenneth A. Thomas, Jr. | Plasminogen activator production |
| US5045565A (en) * | 1987-03-09 | 1991-09-03 | The Procter & Gamble Company | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain |
| US4965200A (en) * | 1989-06-23 | 1990-10-23 | Merck & Co., Inc. | Process for the preparation of 3-keto, 5-hydroxy simvastatin analogs |
| FR2663639B1 (fr) * | 1990-06-26 | 1994-03-18 | Rhone Poulenc Sante | Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation. |
| US5733871A (en) * | 1991-11-08 | 1998-03-31 | The General Hospital Corporation | Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration |
| US6121246A (en) * | 1995-10-20 | 2000-09-19 | St. Elizabeth's Medical Center Of Boston, Inc. | Method for treating ischemic tissue |
| US6086582A (en) * | 1997-03-13 | 2000-07-11 | Altman; Peter A. | Cardiac drug delivery system |
| WO1999001150A1 (en) * | 1997-07-03 | 1999-01-14 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Novel composition for treating, preventing and/or delaying ischemic cell death |
| DE69838526T2 (de) * | 1998-02-05 | 2008-07-03 | Biosense Webster, Inc., Diamond Bar | Gerät zum Freisetzen eines Medikaments im Herzen |
| US20020122792A1 (en) * | 1998-07-24 | 2002-09-05 | Thomas J. Stegmann | Induction of neoangiogenesis in ischemic myocardium |
| US6102887A (en) * | 1998-08-11 | 2000-08-15 | Biocardia, Inc. | Catheter drug delivery system and method for use |
| US20010034023A1 (en) * | 1999-04-26 | 2001-10-25 | Stanton Vincent P. | Gene sequence variations with utility in determining the treatment of disease, in genes relating to drug processing |
| US20020037508A1 (en) * | 2000-01-19 | 2002-03-28 | Michele Cargill | Human single nucleotide polymorphisms |
| US6988004B2 (en) * | 2000-05-16 | 2006-01-17 | Bioheart, Inc. | Method for inducing angiogenesis by electrical stimulation of muscles |
| WO2002046220A2 (en) * | 2000-12-07 | 2002-06-13 | Gencell S.A. | Sequences upstream of the carp gene, vectors containing them and uses thereof |
-
2004
- 2004-06-04 BR BRPI0410844-2A patent/BRPI0410844A/pt not_active IP Right Cessation
- 2004-06-04 JP JP2006508289A patent/JP2006526592A/ja active Pending
- 2004-06-04 EP EP04740314A patent/EP1677831A1/en not_active Withdrawn
- 2004-06-04 CA CA002526792A patent/CA2526792A1/en not_active Abandoned
- 2004-06-04 NZ NZ543717A patent/NZ543717A/en unknown
- 2004-06-04 AU AU2004244756A patent/AU2004244756A1/en not_active Abandoned
- 2004-06-04 WO PCT/EP2004/006903 patent/WO2004108167A1/en not_active Ceased
- 2004-06-04 EA EA200501846A patent/EA009390B1/ru not_active IP Right Cessation
- 2004-06-04 KR KR1020057023058A patent/KR20060052692A/ko not_active Ceased
- 2004-06-07 US US10/861,906 patent/US20050096286A1/en not_active Abandoned
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2010
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2000129133A (ru) * | 1998-04-17 | 2002-10-20 | Анджиодженикс, Инкорпорейтед | Терапевтические ангиогенные факторы и способы их применения |
| WO2002014471A2 (en) * | 2000-08-15 | 2002-02-21 | Phage Biotechnology Corporation | A method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis |
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| Comerota A.J. et al. Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructible lower extremity ischemia: preliminary results of a phase I trial, J. Vasc. Surg. 2002 May; 35 (5): 930-6, referat [Naydeno 11.05.2006]. Naydeno iz Internet: <URL:http://www.ncbi. nlm.nih.gov/entrez/query,fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12021709&query_hl=7&itool=pubmed_DocSum, referat * |
| DEDOV I.I. i dr. Entsiklopediya, M., "Meditsina", 2000, s. 484-487 * |
| Freedmann S.B. Clinical trials of gene therapy for atherosclerotic cardiovascular disease, Curr. Opin. Lipidol. 2002 Dec.; 13 (6): 653-61, referat [Naydeno 11.05. 2006]. Naydeno iz Internet: <URL:http://www.ncbi. nlm.nih.gov/entrez/query, fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12441890&query_hl=11&itool=pubmed__docsum * |
| Rasmussen H.S. et al. Angiogenic gene therapy strategies for the treatment of cardiovascular disease, Curr. Opin. Mol. Ther. 2002 Oct.; 4 (5): 476-81, referat [Naydeno 11.05.2006]. Naydeno iz Internet: <URL:http://www.ncbi. nlm.nih.gov/entrez/query, fcgi?cmd=Retrieve&db=pubmed&dopt= Abstract&list_uids=12435049&query_hl=9&itool=pubmed_DocSum, referat * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1677831A1 (en) | 2006-07-12 |
| JP2006526592A (ja) | 2006-11-24 |
| KR20060052692A (ko) | 2006-05-19 |
| NO20060032L (no) | 2006-01-04 |
| BRPI0410844A (pt) | 2006-06-27 |
| AU2004244756A1 (en) | 2004-12-16 |
| CA2526792A1 (en) | 2004-12-16 |
| NZ543717A (en) | 2008-06-30 |
| US20050096286A1 (en) | 2005-05-05 |
| WO2004108167A1 (en) | 2004-12-16 |
| EA200501846A1 (ru) | 2007-12-28 |
| AU2010257389A1 (en) | 2011-01-27 |
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