JP2006524682A5 - - Google Patents
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- JP2006524682A5 JP2006524682A5 JP2006507414A JP2006507414A JP2006524682A5 JP 2006524682 A5 JP2006524682 A5 JP 2006524682A5 JP 2006507414 A JP2006507414 A JP 2006507414A JP 2006507414 A JP2006507414 A JP 2006507414A JP 2006524682 A5 JP2006524682 A5 JP 2006524682A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- compound according
- compound
- following formula
- substituted lower
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C**C[n]1nc(**N)c(*)n1 Chemical compound C**C[n]1nc(**N)c(*)n1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45656503P | 2003-03-19 | 2003-03-19 | |
| US60/456,565 | 2003-03-19 | ||
| PCT/US2004/008579 WO2004083235A2 (en) | 2003-03-19 | 2004-03-19 | Tie-2 modulators and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006524682A JP2006524682A (ja) | 2006-11-02 |
| JP2006524682A5 true JP2006524682A5 (cg-RX-API-DMAC7.html) | 2007-05-24 |
| JP4960085B2 JP4960085B2 (ja) | 2012-06-27 |
Family
ID=33030100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507414A Expired - Fee Related JP4960085B2 (ja) | 2003-03-19 | 2004-03-19 | Ｔｉｅ−２モジュレータと使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8013156B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1608373A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4960085B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2004221812B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2517291C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004083235A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050124625A1 (en) * | 2003-10-21 | 2005-06-09 | Salvati Mark E. | Piperazine derivatives and their use as modulators of nuclear hormone receptor function |
| ES2450566T3 (es) | 2004-11-30 | 2014-03-25 | Amgen Inc. | Análogos de quinazolina y quinolinas y su uso como medicamentos para tratar el cáncer |
| JO2787B1 (en) | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
| AU2006292256B2 (en) * | 2005-09-19 | 2013-05-02 | Neuronascent, Inc. | Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration |
| AU2013211455B2 (en) * | 2005-09-19 | 2017-12-07 | Neuronascent, Inc. | Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration |
| KR101114704B1 (ko) * | 2006-10-04 | 2012-03-14 | 에프. 호프만-라 로슈 아게 | Ｃｂ2 수용체 조절제로서 피라진-2-카복스아마이드 유도체 |
| CA2729012A1 (en) | 2008-06-27 | 2009-12-30 | Amgen Inc. | Ang-2 inhibition to treat multiple sclerosis |
| GB0818241D0 (en) | 2008-10-06 | 2008-11-12 | Cancer Res Technology | Compounds and their use |
| EP2387563B2 (en) | 2009-01-16 | 2022-04-27 | Exelixis, Inc. | Malate salt of n- (4- { [ 6, 7-bis (methyloxy) quinolin-4-yl]oxy}phenyl-n' - (4 -fluorophenyl) cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer |
| UY33198A (es) * | 2010-01-26 | 2011-08-31 | Boehringer Ingelheim Int | 5-alquinil-pirimidinas. |
| WO2012061337A1 (en) | 2010-11-02 | 2012-05-10 | Exelixis, Inc. | Fgfr2 modulators |
| MY192489A (en) | 2013-10-14 | 2022-08-23 | Eisai R&D Man Co Ltd | Selectively substituted quinoline compounds |
| WO2015057655A1 (en) | 2013-10-14 | 2015-04-23 | Eisai R&D Management Co., Ltd. | Selectively substituted quinoline compounds |
| AR104882A1 (es) | 2015-06-05 | 2017-08-23 | Orion Corp | DERIVADOS DE 2-(1-HETEROARILPIPERAZIN-4-IL)METIL-1,4-BENZODIOXANO COMO ANTAGONISTAS DE a2C |
| AU2023323738A1 (en) * | 2022-08-08 | 2025-01-09 | Ajax Therapeutics, Inc. | Heterocyclic amide and urea compounds as jak2 inhibitors |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI193974A7 (cg-RX-API-DMAC7.html) * | 1973-07-13 | 1975-01-14 | Merck & Co Inc | |
| DE2428030A1 (de) | 1974-06-11 | 1976-01-02 | Merck Sharp & Dohme | Substituierte thiadiazole und verfahren zu ihrer herstellung |
| EP0096006A3 (de) | 1982-05-28 | 1984-12-19 | Ciba-Geigy Ag | 3-(Ureidocyclohexylamino)-propan-1,2-diolderivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen, sowie ihre therapeutische Verwendung |
| US4547505A (en) | 1983-03-25 | 1985-10-15 | Degussa Aktiengesellschaft | N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production |
| US4994476A (en) | 1984-10-31 | 1991-02-19 | Bristol-Myers Company | Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties |
| IT1191845B (it) | 1986-01-20 | 1988-03-23 | Dompe Farmaceutici Spa | Alchiloli derivati farmacologicamente attivi |
| US4954502A (en) | 1988-06-10 | 1990-09-04 | Bristol-Myers Squibb Company | 1-indolyalkyl-4-(substituted-pyridinyl)piperazines |
| SE8803429D0 (sv) | 1988-09-28 | 1988-09-28 | Pharmacia Ab | Novel pyridyl- and pyrimidyl derivatives |
| DE4134467A1 (de) * | 1991-10-18 | 1993-04-22 | Thomae Gmbh Dr K | Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| SE9202265D0 (sv) | 1992-07-31 | 1992-07-31 | Kabi Pharmacia Ab | Novel- pyridyl and pyrimidylpiperazine derivatives |
| TW279864B (cg-RX-API-DMAC7.html) * | 1993-02-19 | 1996-07-01 | Janssen Pharmaceutica Nv | |
| US5639754A (en) * | 1994-07-12 | 1997-06-17 | Janssen Pharmaceutica N.V. | Urea and thiourea derivatives of azolones |
| US5571811A (en) * | 1994-07-12 | 1996-11-05 | Janssen Pharmaceutica N.V. | Sulfonamide derivatives of azolones |
| US5637592A (en) * | 1994-07-12 | 1997-06-10 | Janssen Pharmaceutica N.V. | Acyl derivatives of azolones |
| NZ298499A (en) * | 1995-01-11 | 1998-01-26 | Samjin Pharm Co Ltd | Aromatic piperazine or pyridine derivatives; medicaments thereof |
| PT912559E (pt) * | 1996-07-13 | 2003-03-31 | Glaxo Group Ltd | Compostos heterociclicos fundidos como inibidores de proteina tirosina quinase |
| GB9713087D0 (en) | 1997-06-20 | 1997-08-27 | Celltech Therapeutics Ltd | Chemical compounds |
| JPH1180119A (ja) | 1997-07-15 | 1999-03-26 | Sankyo Co Ltd | ピペラジン誘導体 |
| US6462036B1 (en) | 1998-11-06 | 2002-10-08 | Basf Aktiengesellschaft | Tricyclic pyrazole derivatives |
| ES2220422T3 (es) * | 1999-03-03 | 2004-12-16 | Wyeth | Nuevos derivados de diazol como agentes serotonergicos. |
| SE9901884D0 (sv) * | 1999-05-21 | 1999-05-21 | Pharmacia & Upjohn Ab | Novel compounds their use and preparation |
| MXPA01011905A (es) | 1999-05-21 | 2004-03-19 | Biovitrum Ab | Compuestos novedosos, su uso y preparacion. |
| US6921763B2 (en) * | 1999-09-17 | 2005-07-26 | Abbott Laboratories | Pyrazolopyrimidines as therapeutic agents |
| EP1088821A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonamide derivatives |
| JP2004525071A (ja) * | 2000-07-20 | 2004-08-19 | ニューロジェン コーポレイション | カプサイシン受容体リガンド |
| US7186715B2 (en) | 2001-01-08 | 2007-03-06 | Eli Lilly And Company | Piperazine- and piperidine-derivatives as melanocortin receptor agonists |
| CA2436487A1 (en) * | 2001-01-30 | 2002-08-08 | Cytopia Pty Ltd. | Methods of inhibiting kinases |
| CA2443108A1 (en) * | 2001-04-03 | 2002-10-17 | Merck & Co. Inc. | N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists |
| EP1401831A1 (en) | 2001-07-03 | 2004-03-31 | Chiron Corporation | Indazole benzimidazole compounds as tyrosine and serine/threonine kinase inhibitors |
| AU2003236500B9 (en) * | 2002-06-12 | 2009-07-02 | Chemocentryx, Inc. | 1-aryl-4-substituted piperazine derivatives for use as CCR1 antagonists for the treatment of inflammation and immune disorders |
| US7320979B2 (en) * | 2003-04-14 | 2008-01-22 | Abbott Gmbh & Co. Kg. | N-[(piperazinyl)hetaryl]arylsulfonamide compounds |
-
2004
- 2004-03-19 JP JP2006507414A patent/JP4960085B2/ja not_active Expired - Fee Related
- 2004-03-19 EP EP04757665A patent/EP1608373A4/en not_active Withdrawn
- 2004-03-19 CA CA2517291A patent/CA2517291C/en not_active Expired - Fee Related
- 2004-03-19 AU AU2004221812A patent/AU2004221812B2/en not_active Ceased
- 2004-03-19 WO PCT/US2004/008579 patent/WO2004083235A2/en not_active Ceased
- 2004-03-19 US US10/549,300 patent/US8013156B2/en not_active Expired - Fee Related