JP2008534541A5 - - Google Patents

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Publication number
JP2008534541A5
JP2008534541A5 JP2008503415A JP2008503415A JP2008534541A5 JP 2008534541 A5 JP2008534541 A5 JP 2008534541A5 JP 2008503415 A JP2008503415 A JP 2008503415A JP 2008503415 A JP2008503415 A JP 2008503415A JP 2008534541 A5 JP2008534541 A5 JP 2008534541A5
Authority
JP
Japan
Prior art keywords
alkyl
aryl
heteroaryl
cycloalkyl
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008503415A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008534541A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2006/002769 external-priority patent/WO2006103038A1/en
Publication of JP2008534541A publication Critical patent/JP2008534541A/ja
Publication of JP2008534541A5 publication Critical patent/JP2008534541A5/ja
Pending legal-status Critical Current

Links

JP2008503415A 2005-03-30 2006-03-27 置換１，２−エチレンジアミン、前記化合物を含む薬物、それらの使用及びそれらの製造方法 Pending JP2008534541A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05006939 2005-03-30
PCT/EP2006/002769 WO2006103038A1 (en) 2005-03-30 2006-03-27 Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture

Publications (2)

Publication Number Publication Date
JP2008534541A JP2008534541A (ja) 2008-08-28
JP2008534541A5 true JP2008534541A5 (cg-RX-API-DMAC7.html) 2009-05-14

Family

ID=36545049

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008503415A Pending JP2008534541A (ja) 2005-03-30 2006-03-27 置換１，２−エチレンジアミン、前記化合物を含む薬物、それらの使用及びそれらの製造方法

Country Status (7)

Country Link
US (3) US7713961B2 (cg-RX-API-DMAC7.html)
EP (1) EP1866034A1 (cg-RX-API-DMAC7.html)
JP (1) JP2008534541A (cg-RX-API-DMAC7.html)
AR (1) AR056862A1 (cg-RX-API-DMAC7.html)
CA (1) CA2603404A1 (cg-RX-API-DMAC7.html)
TW (1) TW200716152A (cg-RX-API-DMAC7.html)
WO (1) WO2006103038A1 (cg-RX-API-DMAC7.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1866034A1 (en) * 2005-03-30 2007-12-19 Boehringer Ingelheim International GmbH Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture
CA2617294A1 (en) * 2005-08-03 2007-02-08 Boehringer Ingelheim International Gmbh Substituted ethane-1,2-diamines for the treatment of alzheimer's disease ii
WO2007017511A2 (de) * 2005-08-11 2007-02-15 Boehringer Ingelheim International Gmbh Verbindungen zur behandlung der alzheimer erkrankung
JP2009504612A (ja) * 2005-08-11 2009-02-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アルツハイマー病の治療用化合物
EP1915339A1 (de) * 2005-08-11 2008-04-30 Boehringer Ingelheim International GmbH Inhibitoren der beta-sekretase zur behandlung der alzheimer- erkrankung
US20100168070A1 (en) * 2005-08-11 2010-07-01 Niklas Heine Compounds for the treatment of alzheimer's disease
WO2010042796A1 (en) 2008-10-10 2010-04-15 Purdue Research Foundation Compounds for treatment of alzheimer's disease
CA2744425A1 (en) 2008-11-20 2010-05-27 Purdue Research Foundation Quinazoline inhibitors of bace 1 and methods of using
WO2010065861A2 (en) * 2008-12-05 2010-06-10 Purdue Research Foundation Inhibitors of bace 1 and methods for treating alzheimer's disease
WO2011044057A1 (en) * 2009-10-05 2011-04-14 Comentis, Inc. Sulfonamido pyrrolidine compounds which inhibit beta-secretase activity and methods of use thereof
US20140066488A1 (en) * 2012-08-30 2014-03-06 Purdue Research Foundation Inhibitors of Memapsin 2 Cleavage for the Treatment of Alzheimer's Disease
BR112023026747A2 (pt) 2021-06-18 2024-03-12 Aligos Therapeutics Inc Métodos e composições para direcionamento de pd-l1
CN119212987A (zh) 2021-12-16 2024-12-27 安力高医药股份有限公司 用于靶向pd-l1的方法和组合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ184194A3 (en) 1993-08-09 1995-03-15 Lilly Co Eli Aspartylprotease inhibitor and method of identifying thereof
US7087399B1 (en) 1999-05-13 2006-08-08 Scios, Inc. β-secretase and modulation of β-secretase activity
JP5138851B2 (ja) 1999-06-28 2013-02-06 オクラホマ メディカル リサーチ ファウンデーション 触媒的に活性な組換えメマプシンおよびその使用方法
WO2002100410A1 (en) * 2001-06-08 2002-12-19 Elan Pharmaceuticals, Inc. Methods of treating alzheimer's disease
WO2003032994A2 (de) 2001-10-17 2003-04-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg 5-substituierte 4-amino-2-phenylamino-pyrimidinderivate und ihre verwendung als beta-amyloid modulatoren
CA2472617A1 (en) * 2002-01-04 2003-07-17 Elan Pharmaceuticals, Inc. Substituted amino carboxamides for the treatment of alzheimer's disease
BR0314714A (pt) * 2002-09-27 2005-08-02 Elan Pharm Inc Compostos para o tratamento da doença de alzheimer
WO2004043916A1 (en) * 2002-11-12 2004-05-27 Merck & Co., Inc. Phenylcarboxamide beta-secretase inhibitors for the treatment of alzheimer's disease
US20050090449A1 (en) 2003-05-13 2005-04-28 Boehringer Ingelheim International Gmbh Novel statine derivatives for the treatment of Alzheimer's disease
EP1641748B1 (en) * 2003-06-30 2013-08-28 Merck Sharp & Dohme Corp. N-alkyl phenylcarboxamide beta-secretase inhibitors for the treatment of alzheimer s disease
JP2007538024A (ja) 2004-05-19 2007-12-27 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アミロイドベータペプチドのレベル変化に関連する疾患及び状態の治療方法及び新規エノールカルボキサミド化合物
WO2005113582A1 (en) 2004-05-22 2005-12-01 Boehringer Ingelheim International Gmbh Substituted ethane-1,2-diamines for the treatment of alzheimer's disease
WO2006050862A1 (en) 2004-11-10 2006-05-18 Boehringer Ingelheim International Gmbh Statine derivatives for the treatment of alzheimer's disease
WO2006050861A2 (en) 2004-11-10 2006-05-18 Boehringer Ingelheim International Gmbh Statine derivatives for the treatment of alzheimer's disease
EP1866034A1 (en) * 2005-03-30 2007-12-19 Boehringer Ingelheim International GmbH Substituted 1,2-ethylendiamines, medicaments comprising said compound; their use and their method of manufacture
CA2617294A1 (en) 2005-08-03 2007-02-08 Boehringer Ingelheim International Gmbh Substituted ethane-1,2-diamines for the treatment of alzheimer's disease ii
JP2009504612A (ja) 2005-08-11 2009-02-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アルツハイマー病の治療用化合物

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