JP2006524331A - 生体液のプロテオーム分析 - Google Patents

生体液のプロテオーム分析 Download PDF

Info

Publication number
JP2006524331A
JP2006524331A JP2006507518A JP2006507518A JP2006524331A JP 2006524331 A JP2006524331 A JP 2006524331A JP 2006507518 A JP2006507518 A JP 2006507518A JP 2006507518 A JP2006507518 A JP 2006507518A JP 2006524331 A JP2006524331 A JP 2006524331A
Authority
JP
Japan
Prior art keywords
proteomic profile
protein
infection
maternal
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2006507518A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006524331A5 (enExample
Inventor
ロン ローゼンフェルト,
スリ ナガーラ,
マイク グラベット,
Original Assignee
プロテオジェニックス, インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by プロテオジェニックス, インコーポレイテッド filed Critical プロテオジェニックス, インコーポレイテッド
Publication of JP2006524331A publication Critical patent/JP2006524331A/ja
Publication of JP2006524331A5 publication Critical patent/JP2006524331A5/ja
Ceased legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2006507518A 2003-03-25 2004-03-23 生体液のプロテオーム分析 Ceased JP2006524331A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/400,005 US7191068B2 (en) 2003-03-25 2003-03-25 Proteomic analysis of biological fluids
PCT/US2004/008954 WO2004088324A2 (en) 2003-03-25 2004-03-23 Proteomic analysis of biological fluids

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010044772A Division JP5011410B2 (ja) 2003-03-25 2010-03-01 生体液のプロテオーム分析

Publications (2)

Publication Number Publication Date
JP2006524331A true JP2006524331A (ja) 2006-10-26
JP2006524331A5 JP2006524331A5 (enExample) 2010-04-22

Family

ID=33096805

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006507518A Ceased JP2006524331A (ja) 2003-03-25 2004-03-23 生体液のプロテオーム分析
JP2010044772A Expired - Fee Related JP5011410B2 (ja) 2003-03-25 2010-03-01 生体液のプロテオーム分析

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010044772A Expired - Fee Related JP5011410B2 (ja) 2003-03-25 2010-03-01 生体液のプロテオーム分析

Country Status (12)

Country Link
US (3) US7191068B2 (enExample)
EP (2) EP1618388B1 (enExample)
JP (2) JP2006524331A (enExample)
CN (1) CN1795387A (enExample)
AT (1) ATE423322T1 (enExample)
AU (2) AU2004225527B2 (enExample)
CA (1) CA2560972A1 (enExample)
DE (1) DE602004019511D1 (enExample)
DK (1) DK1618388T3 (enExample)
ES (1) ES2322593T3 (enExample)
MX (1) MXPA05010325A (enExample)
WO (1) WO2004088324A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010526987A (ja) * 2006-12-26 2010-08-05 ブリガム・ヤング・ユニバーシティ 血清プロテオミクスシステムと関連する方法
JP2010534341A (ja) * 2007-07-20 2010-11-04 ザ ユニバーシティ オブ ユタ リサーチ ファウンデーション 早産の危険性を評価するためのバイオマーカーの同定および定量化
JP2013512434A (ja) * 2009-11-25 2013-04-11 ホロジック,インコーポレイテッド 羊膜内感染の検出
JP2013522603A (ja) * 2010-03-11 2013-06-13 ユニバーシティ オブ ルイスビル リサーチ ファンデーション,インコーポレイテッド 妊娠損失リスクを予測する方法および妊娠損失リスクを低下させる方法

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003290775A1 (en) * 2002-11-14 2004-06-03 Ciphergen Biosystems, Inc. Biomarkers for intra-amniotic inflammation
US8068990B2 (en) * 2003-03-25 2011-11-29 Hologic, Inc. Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids
US7191068B2 (en) * 2003-03-25 2007-03-13 Proteogenix, Inc. Proteomic analysis of biological fluids
GB0313828D0 (en) * 2003-06-16 2003-07-23 Owen Smith Brian D O Salivary urate for diagnosis of pre-eclampsia
CA2577587A1 (en) * 2003-08-21 2005-03-03 Mcgill University Method and apparatus for analyzing amniotic fluid
US20050233400A1 (en) * 2004-03-03 2005-10-20 Weiner Carl P Proteomic method for predicting success of rescue cerclage
WO2005093413A2 (en) * 2004-03-22 2005-10-06 Yale University Diagnosis and treatment of preeclampsia
JP2007536939A (ja) * 2004-05-14 2007-12-20 アモークス インコーポレーティッド 免疫細胞バイオセンサーおよびその使用方法
WO2012047930A2 (en) 2010-10-04 2012-04-12 The Regents Of The University Of California Compositions and methods for treatment of gynecologic cancers
US7670792B2 (en) * 2004-07-14 2010-03-02 The Regents Of The University Of California Biomarkers for early detection of ovarian cancer
EP2261672B1 (en) 2004-07-14 2014-09-03 The Regents of The University of California Biomarkers for early detection of ovarian cancer
US9488655B2 (en) * 2004-07-14 2016-11-08 The Regents Of The University Of California Biomarkers for detection of early- and late-stage endometrial cancer
CA2591926A1 (en) * 2004-09-20 2006-03-30 Proteogenix, Inc. Diagnosis of fetal aneuploidy
EP1839057B1 (en) * 2004-12-15 2010-08-25 Beth Israel Deaconess Medical Center Nucleic acids and polypeptides useful for diagnosing and treating complications of pregnancy
CA2595377A1 (en) 2005-01-28 2006-08-03 Children's Medical Center Corporation Methods for diagnosis and prognosis of epithelial cancers
CN101137760B (zh) * 2005-03-18 2011-01-26 香港中文大学 检测染色体非整倍性的方法
CA2605143A1 (en) 2005-04-15 2006-10-26 Becton, Dickinson And Company Diagnosis of sepsis
US20070087387A1 (en) 2005-04-21 2007-04-19 Prasad Devarajan Method for the Early Detection of Renal Disease Using Proteomics
EP2189541A3 (en) * 2005-09-09 2010-09-08 University of Iowa Research Foundation Methods and reagents for treatment and diagnosis of age-related macular degeneration
US7312079B1 (en) 2005-10-06 2007-12-25 Lexicon Pharmaceuticals, Inc. Variants of FAM3C
US20070190580A1 (en) * 2005-10-31 2007-08-16 Beckman Coulter, Inc. Immunoassay of Fragments of Insulin-Like Growth Factor Binding Proteins
US20070162992A1 (en) * 2006-01-09 2007-07-12 Mcgill University Metabolomic determination in assisted reproductive technology
EP1994408A4 (en) * 2006-01-27 2009-05-06 Eastern Virginia Med School PROTEOMIC FINGERPRINTS OF HUMAN IVF EMBRYOES: IDENTIFICATION OF BIOMARKERS WITH DEVELOPMENT POTENTIAL
US7790463B2 (en) 2006-02-02 2010-09-07 Yale University Methods of determining whether a pregnant woman is at risk of developing preeclampsia
WO2007109293A2 (en) * 2006-03-21 2007-09-27 Yale University Early diagnosis of congenital abnormalities in the offspring of diabetic mothers
EP2462946B1 (en) * 2006-08-16 2014-07-09 National Research Council of Canada Method of inhibiting cathepsin activity
AU2007312960A1 (en) * 2006-10-20 2008-04-24 Newcastle Innovation Limited Assay for the detection of biomarkers associated with pregnancy related conditions
WO2008112424A1 (en) * 2007-03-08 2008-09-18 Mayo Foundation For Medical Education And Research Assessing heart failure
CN101680884A (zh) * 2007-05-05 2010-03-24 西安大略大学 检测先兆子痫的方法
GB0711327D0 (en) * 2007-06-12 2007-07-25 Hansa Medical Ab Diagnostic method
FR2919060B1 (fr) 2007-07-19 2012-11-30 Biomerieux Sa Procede de dosage de l'ezrine pour le diagnostic in vitro du cancer colorectal.
AU2008285557B2 (en) 2007-07-19 2014-07-03 Biomerieux Method for the assay of liver fatty acid-binding protein, ACE and CA19-9 for the in vitro diagnosis of colorectal cancer
FR2919065B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine ai pour le diagnostic in vitro du cancer colorectal
FR2919063B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.
WO2009046447A1 (en) * 2007-10-06 2009-04-09 Katalin Polgar Fetal open lesion detection system
JP2011506971A (ja) * 2007-12-13 2011-03-03 スリーエム イノベイティブ プロパティズ カンパニー 創傷試料を解析する方法
US20100016173A1 (en) * 2008-01-30 2010-01-21 Proteogenix, Inc. Maternal serum biomarkers for detection of pre-eclampsia
WO2009097579A1 (en) * 2008-01-30 2009-08-06 Proteogenix, Inc. Gestational age dependent proteomic changes of human maternal serum for monitoring maternal and fetal health
US8669113B2 (en) 2008-04-03 2014-03-11 Becton, Dickinson And Company Advanced detection of sepsis
US8481273B2 (en) * 2008-06-20 2013-07-09 University Of Delaware Perlecan fragments as biomarkers of bone stromal lysis
EP2310859A1 (en) * 2008-06-25 2011-04-20 University of Utah Research Foundation Identifying and quantifying biomarkers associated with preeclampsia
FR2933773B1 (fr) 2008-07-10 2013-02-15 Biomerieux Sa Procede de dosage de la proteine disulfide isomerase pour le diagnostic in vitro du cancer colorectal
US8476008B2 (en) 2008-07-23 2013-07-02 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes
WO2011053832A1 (en) * 2009-10-29 2011-05-05 The Trustees Of Columbia University In The City Of New York Use of urinary ngal to diagnose sepsis in very low birth weight infants
JP2013529907A (ja) 2010-05-24 2013-07-25 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク Ngalタンパク質変異体及びその使用
MX2012013735A (es) * 2010-05-28 2013-04-29 Mind Nrg Sa Isoformas de neuregulina, polipeptidos de neuregulina y usos de los mismos.
GB201016161D0 (en) 2010-09-24 2010-11-10 Hansa Medical Ab Diagnostic method
AU2011340630B2 (en) * 2010-12-06 2017-01-19 Mycartis Nv Biomarkers and parameters for hypertensive disorders of pregnancy
GB201102108D0 (en) 2011-02-07 2011-03-23 Hansa Medical Ab Diagnostic method
US20140162941A1 (en) * 2011-07-27 2014-06-12 Baylor College Of Medicine Process for preparing biological samples
CN104039810A (zh) 2011-08-29 2014-09-10 加利福尼亚大学董事会 使用高密度脂蛋白(hdl)相关分子治疗和预防促炎性病状
KR101142434B1 (ko) * 2011-09-08 2012-05-08 (주)오비메드 조기양막파수 산모에서 비침습적인 양수 내 염증 및 감염의 예측 또는 진단 방법
CN102426243B (zh) * 2011-11-17 2014-03-19 成都创宜生物科技有限公司 以补体因子d为检测指标的子痫前期检测试剂盒的制备方法
WO2014022748A1 (en) 2012-08-03 2014-02-06 Revo Biologics, Inc. The use of antithrombin in extracorporeal membrane oxygenation
EP3382391A1 (en) 2012-10-24 2018-10-03 NYU Winthrop Hospital Non-invasive biomarker to identify subjects at risk of preterm delivery
WO2014081980A2 (en) 2012-11-21 2014-05-30 The Trustees Of Columbia University In The City Of New York Mutant ngal proteins and uses thereof
WO2014095951A1 (en) * 2012-12-20 2014-06-26 Roche Diagnostics Gmbh Characterization of thermostable dna polymerase
GB201305317D0 (en) * 2013-03-22 2013-05-08 Iles Raymond K Prenatal screening for fetal abnormalities and disorders of pregnancy
WO2014210031A1 (en) * 2013-06-25 2014-12-31 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Proteomic biomarkers of sepsis in elderly patients
FR3036188B1 (fr) 2015-05-12 2019-06-07 Biomerieux Prediction du risque de developper, pour des patients admis en service de reanimation, une infection disseminee
EP4321626A3 (en) * 2015-06-19 2024-05-22 Sera Prognostics, Inc. Biomarker pairs for predicting preterm birth
MA45272A (fr) 2015-06-27 2018-05-02 Stimlabs Llc Produits issus de liquide amniotique et procédés d'utilisation
CN105372414B (zh) * 2015-10-09 2017-12-22 成都大熊猫繁育研究基地 大熊猫乳汁中关键因子的分析方法
EP3559253A4 (en) 2016-12-20 2020-08-26 Sangui Bio Pty. Ltd BLOOD PROFILING WITH PROTEASE INHIBITORS
EP4530633A3 (en) 2017-08-18 2025-10-15 Sera Prognostics, Inc. Pregnancy clock proteins for predicting due date and time to birth
MX2020002788A (es) 2017-09-13 2020-09-14 Progenity Inc Biomarcadores de preeclampsia y sistemas y metodos relacionados.
US20190224277A1 (en) * 2018-01-22 2019-07-25 CyPhi LLC Bio-mimetic formulation
EP4070113A4 (en) 2019-12-04 2023-12-20 Biora Therapeutics, Inc. ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS
CN113092773A (zh) * 2019-12-23 2021-07-09 首都医科大学附属北京世纪坛医院 尿液α-胰蛋白酶抑制剂重链H4及其多肽片段在过敏性疾病中的应用
CN113092771A (zh) * 2019-12-23 2021-07-09 首都医科大学附属北京世纪坛医院 尿液α-1B-糖蛋白及其多肽片段在过敏性疾病中的应用
CN111951969A (zh) * 2020-08-05 2020-11-17 中翰盛泰生物技术股份有限公司 Hbp在高危妊娠预测中的应用
CN120233090B (zh) * 2025-03-28 2025-09-09 中日友好医院(中日友好临床医学研究所) 一组尿蛋白标志物及其在制备非小细胞肺癌预后预测产品中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999043851A1 (en) * 1998-02-25 1999-09-02 National University Of Ireland, Cork Hla linked pre-eclampsia and miscarriage susceptibility gene

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5871937A (en) * 1985-04-30 1999-02-16 The Scripps Research Institute Acute phase protein modulating endotoxic activity of lipopolysaccharides, assay methods and polypeptides
US5516702A (en) * 1991-11-06 1996-05-14 Adeza Biomedical Corporation Screening method for identifying women at increased risk for imminent delivery
US6036955A (en) * 1992-03-05 2000-03-14 The Scripps Research Institute Kits and methods for the specific coagulation of vasculature
US5891618A (en) * 1994-01-24 1999-04-06 Xoma Corporation Method for quantifying LBP in body fluids
US5484705A (en) * 1994-01-24 1996-01-16 Xoma Corporation Method for quantifying lipopolysaccharide binding protein
US5932536A (en) * 1994-06-14 1999-08-03 The Rockefeller University Compositions for neutralization of lipopolysaccharides
US20020164818A1 (en) * 1995-05-23 2002-11-07 Gruber Karl F. Mass spectrometric immunoassay analysis of specific proteins and variants present in various biological fluids
WO1996037777A1 (en) * 1995-05-23 1996-11-28 Nelson Randall W Mass spectrometric immunoassay
US6324479B1 (en) * 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
US6406921B1 (en) * 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
EP1143246A4 (en) * 1998-12-28 2004-11-24 Advance Kk IDENTIFICATION SYSTEM OF MICROORGANISMS
AU3712200A (en) * 1999-03-01 2000-09-21 Board Of Trustees Of The Leland Stanford Junior University Rapid assay for chorioamnionitis
WO2000060354A1 (en) * 1999-04-07 2000-10-12 Unilever Plc Lipopolysaccharide immunoassay and test device
AU6615500A (en) * 1999-07-28 2001-02-19 Genetics Institute Inc. Preventing immune-mediated abortion by inhibiting costimulation
US6653151B2 (en) * 1999-07-30 2003-11-25 Large Scale Proteomics Corporation Dry deposition of materials for microarrays using matrix displacement
CN1433481A (zh) * 1999-11-30 2003-07-30 奥克索化学有限公司 通过基因表达分析评价和预测临术预后
AU2003219275B2 (en) * 2002-03-07 2008-01-24 Cambridge Enterprise Ltd SCD fingerprints
CN1395103A (zh) * 2002-07-31 2003-02-05 中华人民共和国北京出入境检验检疫局 疯牛病病原检测压电生物芯片及其制备方法
AU2003290775A1 (en) 2002-11-14 2004-06-03 Ciphergen Biosystems, Inc. Biomarkers for intra-amniotic inflammation
AU2003290773A1 (en) * 2003-02-05 2004-09-06 Ciphergen Biosystems, Inc. Non-invasive assessment of intra-amniotic environment
US7191068B2 (en) * 2003-03-25 2007-03-13 Proteogenix, Inc. Proteomic analysis of biological fluids
WO2005017192A2 (en) * 2003-08-14 2005-02-24 The General Hospital Corporation Screening for gestational disorders
US7344892B2 (en) * 2003-09-23 2008-03-18 Beth Israel Deaconess Medical Center, Inc. Screening for gestational disorders
US20060063162A1 (en) * 2004-09-23 2006-03-23 Deng David X Biological marker for inflammation
US20060078998A1 (en) * 2004-09-28 2006-04-13 Singulex, Inc. System and methods for sample analysis
GB0426982D0 (en) * 2004-12-09 2005-01-12 Secr Defence Early detection of sepsis
US20070092911A1 (en) * 2005-10-03 2007-04-26 Buechler Kenneth F Methods and compositions for diagnosis and /or prognosis in systemic inflammatory response syndromes
CA2605143A1 (en) * 2005-04-15 2006-10-26 Becton, Dickinson And Company Diagnosis of sepsis
DE602006019262D1 (de) * 2005-08-11 2011-02-10 Siemens Healthcare Diagnostics QUANTITATIVE ASSAYS FÜR PDGFR-beta- IN KÖRPERFLÜSSIGKEITEN
US20090075387A1 (en) * 2005-10-14 2009-03-19 Kalns John E Methods and Compositions for Biomarkers Associated with Change in Physical Performance
US7790463B2 (en) * 2006-02-02 2010-09-07 Yale University Methods of determining whether a pregnant woman is at risk of developing preeclampsia
WO2007092427A2 (en) * 2006-02-06 2007-08-16 Palingen, Inc. Treatment of endotoxemia using endotoxin neutralizing agents
JP2009536641A (ja) * 2006-05-31 2009-10-15 ハンワ ケミカル コーポレイション Vcam−1特異的モノクローナル抗体
US20080199426A1 (en) * 2007-01-11 2008-08-21 Sukhatme Vikas P Methods and compositions for the treatment and diagnosis of vascular inflammatory disorders or endothelial cell disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999043851A1 (en) * 1998-02-25 1999-09-02 National University Of Ireland, Cork Hla linked pre-eclampsia and miscarriage susceptibility gene

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010526987A (ja) * 2006-12-26 2010-08-05 ブリガム・ヤング・ユニバーシティ 血清プロテオミクスシステムと関連する方法
JP2010534341A (ja) * 2007-07-20 2010-11-04 ザ ユニバーシティ オブ ユタ リサーチ ファウンデーション 早産の危険性を評価するためのバイオマーカーの同定および定量化
JP2013512434A (ja) * 2009-11-25 2013-04-11 ホロジック,インコーポレイテッド 羊膜内感染の検出
JP2013522603A (ja) * 2010-03-11 2013-06-13 ユニバーシティ オブ ルイスビル リサーチ ファンデーション,インコーポレイテッド 妊娠損失リスクを予測する方法および妊娠損失リスクを低下させる方法
US9068990B2 (en) 2010-03-11 2015-06-30 University Of Louisville Research Foundation, Inc. Methods of predicting and decreasing the risk of pregnancy loss

Also Published As

Publication number Publication date
ATE423322T1 (de) 2009-03-15
CN1795387A (zh) 2006-06-28
JP5011410B2 (ja) 2012-08-29
JP2010122238A (ja) 2010-06-03
MXPA05010325A (es) 2006-03-17
US20080299594A1 (en) 2008-12-04
ES2322593T3 (es) 2009-06-23
WO2004088324A3 (en) 2005-06-02
EP1618388A2 (en) 2006-01-25
AU2004225527A1 (en) 2004-10-14
WO2004088324A2 (en) 2004-10-14
EP1618388B1 (en) 2009-02-18
US7191068B2 (en) 2007-03-13
US20040197930A1 (en) 2004-10-07
US20090055099A1 (en) 2009-02-26
DE602004019511D1 (de) 2009-04-02
AU2010200352A1 (en) 2010-02-18
CA2560972A1 (en) 2004-10-14
DK1618388T3 (da) 2009-05-18
AU2004225527B2 (en) 2009-10-29
EP2088433A1 (en) 2009-08-12

Similar Documents

Publication Publication Date Title
JP5011410B2 (ja) 生体液のプロテオーム分析
JP2006524331A5 (enExample)
US8068990B2 (en) Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids
US8663576B2 (en) Detection of intraamniotic infection
RU2673074C2 (ru) Биомаркеры и параметры для определения гипертензивных расстройств при беременности
US20100017143A1 (en) Gestational age dependent proteomic changes of human maternal serum for monitoring maternal and fetal health
JP2012516445A (ja) 体液における新生児敗血症の検出のためのバイオマーカー
HK1133922A (en) Proteomic analysis of biological fluids
HK1129926B (en) Proteomic analysis of cervical-vaginal fluids for detecting intra-uterine infection or determining pre-term delivery risk in a pregnant female
Tan et al. Preterm intraamniotic infection and inflammation: Search for protein biomarkers via proteomics approach
HK1173775A (en) Detection of intraamniotic infection

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070306

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090831

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091127

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091204

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20100301

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100521

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100527

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20100729

A045 Written measure of dismissal of application [lapsed due to lack of payment]

Free format text: JAPANESE INTERMEDIATE CODE: A045

Effective date: 20101122