JP2006522821A5 - - Google Patents
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- Publication number
- JP2006522821A5 JP2006522821A5 JP2006509880A JP2006509880A JP2006522821A5 JP 2006522821 A5 JP2006522821 A5 JP 2006522821A5 JP 2006509880 A JP2006509880 A JP 2006509880A JP 2006509880 A JP2006509880 A JP 2006509880A JP 2006522821 A5 JP2006522821 A5 JP 2006522821A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- alanine
- beta
- dipeptide
- grams
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 56
- UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 claims 23
- 108010087806 Carnosine Proteins 0.000 claims 13
- 229940000635 beta-alanine Drugs 0.000 claims 11
- SLRNWACWRVGMKD-UHFFFAOYSA-N L-anserine Natural products CN1C=NC(CC(NC(=O)CCN)C(O)=O)=C1 SLRNWACWRVGMKD-UHFFFAOYSA-N 0.000 claims 8
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 210000002027 skeletal muscle Anatomy 0.000 claims 5
- 108010085443 Anserine Proteins 0.000 claims 4
- SLRNWACWRVGMKD-QMMMGPOBSA-N Balenine Chemical compound CN1C=NC(C[C@H](N=C(O)CCN)C(O)=O)=C1 SLRNWACWRVGMKD-QMMMGPOBSA-N 0.000 claims 4
- 108010084730 N(beta)-alanyl-1-methyl-histidine Proteins 0.000 claims 4
- 241000210053 Potentilla elegans Species 0.000 claims 4
- MYYIAHXIVFADCU-QMMMGPOBSA-N anserine Chemical compound CN1C=NC=C1C[C@H](NC(=O)CC[NH3+])C([O-])=O MYYIAHXIVFADCU-QMMMGPOBSA-N 0.000 claims 4
- -1 beta-alanine amino acid Chemical class 0.000 claims 4
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 claims 4
- 229960002885 histidine Drugs 0.000 claims 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 4
- 108010016626 Dipeptides Proteins 0.000 claims 3
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 claims 2
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims 2
- QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 claims 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- 102000004877 Insulin Human genes 0.000 claims 2
- 108090001061 Insulin Proteins 0.000 claims 2
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims 2
- 229940044199 carnosine Drugs 0.000 claims 2
- 229960003624 creatine Drugs 0.000 claims 2
- 239000006046 creatine Substances 0.000 claims 2
- 235000015872 dietary supplement Nutrition 0.000 claims 2
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 2
- 229940125396 insulin Drugs 0.000 claims 2
- 210000003205 muscle Anatomy 0.000 claims 2
- 235000011496 sports drink Nutrition 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- OSCCDBFHNMXNME-WDCZJNDASA-N (2s,3s,4r)-2-amino-4-hydroxy-3-methylpentanoic acid Chemical compound C[C@@H](O)[C@@H](C)[C@H](N)C(O)=O OSCCDBFHNMXNME-WDCZJNDASA-N 0.000 claims 1
- KMXXSJLYVJEBHI-UHFFFAOYSA-N 3-guanidinopropanoic acid Chemical compound NC(=[NH2+])NCCC([O-])=O KMXXSJLYVJEBHI-UHFFFAOYSA-N 0.000 claims 1
- 229940123208 Biguanide Drugs 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims 1
- 229940123464 Thiazolidinedione Drugs 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- AGBQKNBQESQNJD-UHFFFAOYSA-N alpha-Lipoic acid Natural products OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims 1
- 229940024606 amino acid Drugs 0.000 claims 1
- 235000001014 amino acid Nutrition 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 150000004283 biguanides Chemical class 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- OSCCDBFHNMXNME-UHFFFAOYSA-N gamma-hydroxyisoleucine Natural products CC(O)C(C)C(N)C(O)=O OSCCDBFHNMXNME-UHFFFAOYSA-N 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 229960000367 inositol Drugs 0.000 claims 1
- 230000002045 lasting effect Effects 0.000 claims 1
- 235000019136 lipoic acid Nutrition 0.000 claims 1
- 239000003607 modifier Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-O oxonium Chemical compound [OH3+] XLYOFNOQVPJJNP-UHFFFAOYSA-O 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
- 150000001467 thiazolidinediones Chemical class 0.000 claims 1
- 229960002663 thioctic acid Drugs 0.000 claims 1
- 229910052720 vanadium Inorganic materials 0.000 claims 1
- LEONUFNNVUYDNQ-UHFFFAOYSA-N vanadium atom Chemical compound [V] LEONUFNNVUYDNQ-UHFFFAOYSA-N 0.000 claims 1
- 150000003682 vanadium compounds Chemical class 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46223803P | 2003-04-10 | 2003-04-10 | |
| US10/717,217 US7504376B2 (en) | 1996-08-12 | 2003-11-18 | Methods and compositions for increasing the anaerobic working capacity in tissues |
| PCT/US2004/011050 WO2004091497A2 (en) | 2003-04-10 | 2004-04-08 | Methods and compositions for increasing the anaerobic working capacity in tissues |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010006014A Division JP2010150263A (ja) | 2003-04-10 | 2010-01-14 | 組織における無酸素性作業能力を高めるための方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006522821A JP2006522821A (ja) | 2006-10-05 |
| JP2006522821A5 true JP2006522821A5 (enExample) | 2009-07-30 |
Family
ID=33303070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509880A Pending JP2006522821A (ja) | 2003-04-10 | 2004-04-08 | 組織における無酸素性作業能力を高めるための方法及び組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (9) | US7504376B2 (enExample) |
| EP (1) | EP1610800A4 (enExample) |
| JP (1) | JP2006522821A (enExample) |
| CA (1) | CA2521987C (enExample) |
| WO (1) | WO2004091497A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965596A (en) | 1997-08-12 | 1999-10-12 | Harris; Roger | Methods and compositions for increasing the anaerobic working capacity in tissue |
| US7504376B2 (en) | 1996-08-12 | 2009-03-17 | Natural Alternatives International | Methods and compositions for increasing the anaerobic working capacity in tissues |
| US20050215640A1 (en) | 2004-03-26 | 2005-09-29 | Baxter Jeffrey H | HMB compositions and uses thereof |
| US20060083793A1 (en) * | 2004-09-29 | 2006-04-20 | Gardiner Paul T | Nutritional composition for promoting muscle performance and acting as hydrogen (H+) blocker |
| US20090087495A1 (en) * | 2005-05-19 | 2009-04-02 | Nippon Meat Packers, Inc. | Food for Improving Motor Function |
| CN101309688B (zh) | 2005-05-23 | 2016-06-22 | 自然选择国际公司 | 持续释放β-丙氨酸的组合物和方法 |
| DE602005012089D1 (de) * | 2005-08-04 | 2009-02-12 | Extarma Ag | Flüssige Zusammensetzung enthaltend Arginine und alpha-Liponsäure zur Verbesserung der sexuellen Funktion |
| CA2632262C (en) * | 2005-12-19 | 2015-04-07 | Abbott Laboratories | Method of using .beta.-hydroxy-.beta.-methylbutyrate |
| DE102008024206A1 (de) * | 2008-05-14 | 2009-11-19 | Symrise Gmbh & Co. Kg | Aromakompositionen und Zubereitungen umfassend Nα-β-Alanyl-Dipeptide |
| JP5519945B2 (ja) * | 2009-03-10 | 2014-06-11 | 株式会社ファンケル | 抗不安剤 |
| NO333013B1 (no) * | 2009-07-06 | 2013-02-18 | Smartfish As | Sammensetning omfattende bioaktive aminosyrer eller derivater derav og marin olje i en stabil olje-i-vannemulsjon, og fremgangsmate for fremstilling av nevnte sammensetning. |
| US20090312419A1 (en) * | 2009-08-12 | 2009-12-17 | Kneller Bruce W | CREATINE -ßALANINATE: A NOVEL SALT FOR INCREASING ATHLETIC PERFORMANCE |
| US9693577B2 (en) | 2010-01-29 | 2017-07-04 | Abbott Laboratories | Method of preparing a nutritional powder comprising spray dried HMB |
| ES2481865T3 (es) | 2010-01-29 | 2014-07-31 | Abbott Laboratories | Emulsiones nutricionales que comprenden HMB de calcio |
| PE20121730A1 (es) | 2010-01-29 | 2013-01-13 | Abbott Lab | Liquidos nutricionales envasados asepticamente que comprenden beta-hidroxi-beta-metilbutirato (hmb) |
| TWI526161B (zh) | 2010-06-10 | 2016-03-21 | 亞培公司 | 包含鈣ｈｍｂ及可溶性蛋白質之實質上透明營養液 |
| US8815899B1 (en) * | 2011-03-14 | 2014-08-26 | Intervene Biomedical | Nutritional activation of telomerase in vitro and in vivo with increased safety |
| BR112013031496A2 (pt) * | 2011-06-07 | 2016-12-27 | Ajinomoto Kk | composição de aminoácidos |
| EP2666365A1 (en) * | 2012-05-22 | 2013-11-27 | Taminco | Treatment of poultry, pigs or fish for reducing the feed conversion ratio. |
| ITMI20121586A1 (it) * | 2012-09-24 | 2014-03-25 | N G C Medical Spa | L-carnosina per il trattamento delle miopatia congenita mitocondriale e della sindrome della fatica muscolare cronica |
| AU2014209028C1 (en) | 2013-01-28 | 2019-08-29 | Hector L. Lopez | Methods of improving tolerability, pharmacodynamics, and efficacy of b-alanine and use therefor |
| US20160100615A1 (en) | 2014-10-10 | 2016-04-14 | Sudarshan Narasimhan | Hunger minimized juice fasting system |
| US11344497B1 (en) | 2017-12-08 | 2022-05-31 | Quicksilver Scientific, Inc. | Mitochondrial performance enhancement nanoemulsion |
| US10722465B1 (en) | 2017-12-08 | 2020-07-28 | Quicksilber Scientific, Inc. | Transparent colloidal vitamin supplement |
| US11291702B1 (en) | 2019-04-15 | 2022-04-05 | Quicksilver Scientific, Inc. | Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method |
| US11547688B2 (en) | 2019-08-22 | 2023-01-10 | Nodari Rizun | Amino acid compositions and methods of manufacturing the compositions |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2734081A (en) | 1956-02-07 | Preparation of | ||
| US556110A (en) * | 1896-03-10 | Shutter-closer | ||
| US2364538A (en) | 1941-10-03 | 1944-12-05 | American Cyanamid Co | Preparation of beta-alanine |
| US2334163A (en) | 1942-06-25 | 1943-11-16 | American Cyanamid Co | Preparation of beta-alanine |
| US2416630A (en) | 1942-06-25 | 1947-02-25 | American Cyanamid Co | Preparation of beta-alanine |
| US2336067A (en) | 1942-06-25 | 1943-12-07 | Lederie Lab Inc | Preparation of beta-alanine |
| US5966457A (en) | 1955-06-14 | 1999-10-12 | Lemelson; Jerome H. | Method for inspecting, coding and sorting objects |
| US3966988A (en) | 1971-07-28 | 1976-06-29 | International Flavors & Fragrances Inc. | Flavoring compositions and processes utilizing dithiazine compounds |
| USRE30370E (en) | 1971-11-04 | 1980-08-12 | International Flavors & Fragrances Inc. | Flavoring foodstuffs with a thioester |
| DE2211019C3 (de) * | 1972-03-08 | 1980-08-28 | Bayer Ag, 5090 Leverkusen | Geschmacksverbessernde Formulierungen oraler Penicilline |
| DE2519656A1 (de) * | 1974-05-13 | 1975-11-27 | Sandoz Ag | Neue peptide und verfahren zu ihrer herstellung |
| US3934036A (en) * | 1975-01-23 | 1976-01-20 | Kyorin Seiyaku Kabushiki Kaisha | N-benzenesulfonyl-β-alanine hydrazide useful as an immunosuppressive agent |
| JPS54159393A (en) | 1978-06-08 | 1979-12-17 | Ajinomoto Co Inc | Polyamino acid-coated activated carbon |
| JPS6016934A (ja) | 1983-07-06 | 1985-01-28 | Kaneshiro Nagai | 抗腫瘍剤 |
| IT1176983B (it) * | 1984-10-16 | 1987-08-26 | Zambon Spa | Dipeptidi ad attivita' farmacologica |
| JPS61204120A (ja) | 1985-03-07 | 1986-09-10 | Kaneshiro Nagai | 免疫調節剤 |
| DE3613758A1 (de) * | 1986-04-23 | 1987-10-29 | Consortium Elektrochem Ind | Cysteinreiche, (gamma)-glutaminsaeure- und (beta)-alanin-einheiten aufweisende peptide, verfahren zu deren herstellung und ihre verwendung |
| US4833125A (en) | 1986-12-05 | 1989-05-23 | The General Hospital Corporation | Method of increasing bone mass |
| FR2609893B1 (fr) | 1987-01-26 | 1990-03-30 | Rougereau Andre | Composition a base d'acides amines et de vitamines utilisable en therapeutique cancerologique |
| JPS6442425A (en) | 1987-08-11 | 1989-02-14 | Nippon Univ | Remedy for cachexia |
| JPS6442425U (enExample) | 1987-09-10 | 1989-03-14 | ||
| EP0436611A4 (en) | 1988-09-28 | 1992-03-11 | Peptide Technology Ltd | Compound and method for the retardation of collagen cross-linking |
| US5208217A (en) | 1989-04-20 | 1993-05-04 | Mount Sinai School Of Medicine Of The City University Of New York | Hepatospecific insulin analogues |
| JPH0395125A (ja) | 1989-05-23 | 1991-04-19 | Otsuka Pharmaceut Co Ltd | カルシウム代謝改善剤 |
| FR2658013B1 (fr) | 1990-02-02 | 1992-04-17 | Thomson Csf | Filtre a ondes acoustiques de surface. |
| IT1240336B (it) | 1990-03-21 | 1993-12-07 | Setra | Composizioni farmaceutiche,dietetiche o veterinarie ad attivita' eumetabolica |
| US5122515A (en) | 1990-06-19 | 1992-06-16 | Smith Ross C | Nutrient composition containing dipeptides and method for administering the same |
| JP2873493B2 (ja) | 1990-08-09 | 1999-03-24 | 理化学研究所 | 血糖調節剤 |
| JP2873497B2 (ja) | 1990-09-03 | 1999-03-24 | 理化学研究所 | 脂質代謝調節剤 |
| WO1993004690A1 (en) * | 1991-09-09 | 1993-03-18 | Peptide Technology Limited | Method for the treatment of the complications and pathology of diabetes |
| JPH0624976A (ja) | 1992-07-10 | 1994-02-01 | Rikagaku Kenkyusho | 輸液用組成物 |
| GB9215746D0 (en) | 1992-07-24 | 1992-09-09 | Hultman Eric | A method of increasing creatine supply depot |
| JP3213666B2 (ja) | 1994-02-28 | 2001-10-02 | 治彦 末岡 | クレアチン飲料の製造方法 |
| DE69529043T2 (de) * | 1994-09-30 | 2003-05-08 | L'oreal S.A., Paris | Verwendung von einem Agonisten eines mit einem Chloridkanal assozierten Rezeptors zur Behandlung von Hautfalten |
| JP3595373B2 (ja) | 1995-02-20 | 2004-12-02 | 治彦 末岡 | クレアチン飲料 |
| WO1997026893A1 (en) * | 1996-01-24 | 1997-07-31 | Aliatros Medical, A.S. | Composition for treating cancer containing a ribose compound, beta-alanine, ascorbic acid and nicotinic acid |
| US7150880B2 (en) | 1996-05-31 | 2006-12-19 | The Original Creatine Patent Co. Ltd. | Compositions containing creatine and creatinine and a methyl xanthine |
| US6274161B1 (en) | 1996-05-31 | 2001-08-14 | The Howard Foundation | Compositions containing creatine in suspension |
| US6524611B2 (en) | 1996-05-31 | 2003-02-25 | The Howard Foundation | Compositions containing creatine and creatinine |
| US6168802B1 (en) | 1996-05-31 | 2001-01-02 | The Howard Foundation | Compositions containing creatine and aloe vera extract |
| GB9611356D0 (en) | 1996-05-31 | 1996-08-07 | Howard Alan N | Improvements in or relating to compositions containing Creatine, and other ergogenic compounds |
| US8128955B2 (en) | 1996-05-31 | 2012-03-06 | The Original Creatine Patent Company | Food compositions containing creatine |
| AU4029397A (en) * | 1996-08-12 | 1998-03-06 | Mark Dunnett | Methods and compositions for increasing the anaerobic working capacity in tissues |
| US5965596A (en) * | 1997-08-12 | 1999-10-12 | Harris; Roger | Methods and compositions for increasing the anaerobic working capacity in tissue |
| US7504376B2 (en) * | 1996-08-12 | 2009-03-17 | Natural Alternatives International | Methods and compositions for increasing the anaerobic working capacity in tissues |
| JP2002051730A (ja) * | 2000-08-08 | 2002-02-19 | Nippon Meat Packers Inc | スポーツ用食品 |
| US6855727B2 (en) | 2000-12-04 | 2005-02-15 | Yaizu Suisankagaku Industry Co., Ltd. | Muscular fatigue-controlling composition and method for providing muscular fatigue-controlling effect |
| US6903136B2 (en) | 2002-04-22 | 2005-06-07 | Experimental And Applied Sciences, Inc. | Food supplements containing 4-hydroxyisoleucine and creatine |
| CN101309688B (zh) | 2005-05-23 | 2016-06-22 | 自然选择国际公司 | 持续释放β-丙氨酸的组合物和方法 |
-
2003
- 2003-11-18 US US10/717,217 patent/US7504376B2/en not_active Expired - Lifetime
-
2004
- 2004-04-08 WO PCT/US2004/011050 patent/WO2004091497A2/en not_active Ceased
- 2004-04-08 CA CA2521987A patent/CA2521987C/en not_active Expired - Lifetime
- 2004-04-08 JP JP2006509880A patent/JP2006522821A/ja active Pending
- 2004-04-08 EP EP04749952A patent/EP1610800A4/en not_active Withdrawn
-
2008
- 2008-08-29 US US12/231,240 patent/US7825084B2/en not_active Expired - Fee Related
-
2010
- 2010-08-10 US US12/806,356 patent/US8129422B2/en not_active Expired - Fee Related
-
2011
- 2011-08-22 US US13/215,073 patent/US8067381B1/en not_active Expired - Fee Related
-
2012
- 2012-01-23 US US13/356,182 patent/US8470865B2/en not_active Expired - Fee Related
-
2013
- 2013-05-22 US US13/900,244 patent/US8993610B2/en not_active Expired - Fee Related
-
2015
- 2015-03-30 US US14/673,556 patent/US9668994B2/en not_active Expired - Fee Related
-
2017
- 2017-03-31 US US15/476,620 patent/US9907770B2/en not_active Expired - Lifetime
-
2018
- 2018-02-27 US US15/906,530 patent/US10881629B2/en not_active Expired - Fee Related
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