JP2006518732A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006518732A5 JP2006518732A5 JP2006502683A JP2006502683A JP2006518732A5 JP 2006518732 A5 JP2006518732 A5 JP 2006518732A5 JP 2006502683 A JP2006502683 A JP 2006502683A JP 2006502683 A JP2006502683 A JP 2006502683A JP 2006518732 A5 JP2006518732 A5 JP 2006518732A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- active ingredient
- pharmaceutical composition
- tetrazolylalkoxydihydrocarbostyril
- dihydrocarbostyril
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44943503P | 2003-02-25 | 2003-02-25 | |
| US44958903P | 2003-02-26 | 2003-02-26 | |
| PCT/JP2004/002146 WO2004075897A1 (en) | 2003-02-25 | 2004-02-24 | Pten inhibitor or maxi-k channels opener |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010180661A Division JP5208172B2 (ja) | 2003-02-25 | 2010-08-12 | PTEN阻害剤またはMaxi−Kチャンネルオープナー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006518732A JP2006518732A (ja) | 2006-08-17 |
| JP2006518732A5 true JP2006518732A5 (https=) | 2006-11-24 |
| JP4590397B2 JP4590397B2 (ja) | 2010-12-01 |
Family
ID=32930512
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006502683A Expired - Fee Related JP4590397B2 (ja) | 2003-02-25 | 2004-02-24 | PTEN阻害剤またはMaxi−Kチャンネルオープナー |
| JP2010180661A Expired - Lifetime JP5208172B2 (ja) | 2003-02-25 | 2010-08-12 | PTEN阻害剤またはMaxi−Kチャンネルオープナー |
| JP2013002314A Expired - Lifetime JP5566482B2 (ja) | 2003-02-25 | 2013-01-10 | PTEN阻害剤またはMaxi−Kチャンネルオープナー |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010180661A Expired - Lifetime JP5208172B2 (ja) | 2003-02-25 | 2010-08-12 | PTEN阻害剤またはMaxi−Kチャンネルオープナー |
| JP2013002314A Expired - Lifetime JP5566482B2 (ja) | 2003-02-25 | 2013-01-10 | PTEN阻害剤またはMaxi−Kチャンネルオープナー |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US7825130B2 (https=) |
| EP (1) | EP1599205B1 (https=) |
| JP (3) | JP4590397B2 (https=) |
| KR (1) | KR101031163B1 (https=) |
| CN (2) | CN101829116B (https=) |
| AR (1) | AR043379A1 (https=) |
| AT (1) | ATE345800T1 (https=) |
| AU (1) | AU2004216340B9 (https=) |
| BR (1) | BRPI0407832A (https=) |
| CA (1) | CA2515590C (https=) |
| CY (1) | CY1106294T1 (https=) |
| DE (1) | DE602004003348T2 (https=) |
| DK (1) | DK1599205T3 (https=) |
| ES (1) | ES2276282T3 (https=) |
| MX (1) | MXPA05008996A (https=) |
| MY (1) | MY136863A (https=) |
| PT (1) | PT1599205E (https=) |
| TW (1) | TWI323660B (https=) |
| WO (1) | WO2004075897A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI323660B (en) * | 2003-02-25 | 2010-04-21 | Otsuka Pharma Co Ltd | Pten inhibitor or maxi-k channels opener |
| TW200848041A (en) | 2007-03-30 | 2008-12-16 | Otsuka Pharma Co Ltd | A medicament for treating schizophrenia comprising cilostazol |
| RU2469723C2 (ru) * | 2007-05-22 | 2012-12-20 | Оцука Фармасьютикал Ко., Лтд. | Лекарственное средство, содержащее производное карбостирила и донепезил, для лечения болезни альцгеймера |
| AR067746A1 (es) * | 2007-08-02 | 2009-10-21 | Otsuka Pharma Co Ltd | Un medicamento para tratar glaucoma que comprende como elemento activo compuesto de ciclodextrina - clatrato de cilostazol |
| AU2009205771B2 (en) | 2008-01-17 | 2014-12-11 | Kui Liu | Methods for in vitro maturation of ovarian follicles |
| AR070816A1 (es) * | 2008-03-14 | 2010-05-05 | Otsuka Pharma Co Ltd | Farmaco de combinacion para tratar trastornos vasculares |
| US20110189308A1 (en) * | 2008-03-17 | 2011-08-04 | Asa Abeliovich | Methods to treat neurodegenerative conditions or diseases by targeting components of a pten signaling pathway |
| EP2502623B1 (en) * | 2008-06-06 | 2016-04-06 | Children's Medical Center Corporation | Promoting Axon Regeneration in the Adult CNS through Control of Protein Translation |
| CA2777628C (en) | 2009-10-16 | 2019-12-03 | The University Of British Columbia | Inhibitors of phosphatase and tensin homolog (pten) compositions, uses and methods |
| EP2322163A1 (en) * | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
| EP2773382A4 (en) | 2011-11-01 | 2016-03-23 | Childrens Medical Center | SIMULTANEOUS ACTIVATION OF MTOR AND STAT3 PATHS TO PROMOTE NEURONAL SURVIVAL AND REGENERATION |
| KR20150027800A (ko) | 2012-06-15 | 2015-03-12 | 고에키 자이단 호징 센탄 이료 신코 자이단 | 경도 인지 장해의 예방 및/또는 치료제 |
| JP2016040542A (ja) * | 2014-08-13 | 2016-03-24 | 学校法人金沢医科大学 | 認知症治療薬または認知症治療薬候補物質のスクリーニング方法 |
| JP2017070404A (ja) * | 2015-10-06 | 2017-04-13 | アンディ チャオ | トイレ床面の清潔な芳香パッド |
| WO2017199755A1 (ja) * | 2016-05-19 | 2017-11-23 | 国立研究開発法人国立循環器病研究センター | 認知症の予防及び/又は治療のための薬剤 |
| EP4151213A4 (en) * | 2020-05-11 | 2024-05-29 | Shimadzu Corporation | THERAPEUTIC FOR MILD COGNITIVE IMPAIRMENT |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535019A (en) * | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| JPS5649378A (en) * | 1979-08-25 | 1981-05-02 | Otsuka Pharmaceut Co Ltd | Tetrazolylalkoxycarbostyril derivative |
| JPH0653666B2 (ja) | 1990-10-22 | 1994-07-20 | 大塚製薬株式会社 | ヒトの糖尿病性知覚障害および末梢神経障害の治療剤 |
| JPH0614444A (ja) * | 1992-06-25 | 1994-01-21 | Central Japan Railway Co | 電力ケーブル接続部の固定装置 |
| AU5715994A (en) * | 1992-12-24 | 1994-07-19 | Otsuka Pharmaceutical Co., Ltd. | Psoriasis remedy |
| JPH06239745A (ja) * | 1992-12-24 | 1994-08-30 | Otsuka Pharmaceut Co Ltd | 乾癬治療剤 |
| JPH0776584A (ja) | 1993-09-07 | 1995-03-20 | Otsuka Pharmaceut Co Ltd | 内皮細胞障害抑制剤 |
| JP3944257B2 (ja) | 1995-12-07 | 2007-07-11 | 大塚製薬株式会社 | 肝実質細胞増殖因子産生増加剤 |
| US6322524B1 (en) * | 1997-08-28 | 2001-11-27 | Visco Technologies, Inc. | Dual riser/single capillary viscometer |
| US6322525B1 (en) * | 1997-08-28 | 2001-11-27 | Visco Technologies, Inc. | Method of analyzing data from a circulating blood viscometer for determining absolute and effective blood viscosity |
| US6019735A (en) * | 1997-08-28 | 2000-02-01 | Visco Technologies, Inc. | Viscosity measuring apparatus and method of use |
| US6428488B1 (en) * | 1997-08-28 | 2002-08-06 | Kenneth Kensey | Dual riser/dual capillary viscometer for newtonian and non-newtonian fluids |
| MXPA00010254A (es) * | 1998-05-01 | 2002-08-06 | R Cutler Neal | Tratamiento de disfuncion sexual en ciertos grupos de pacientes. |
| US6187790B1 (en) * | 1999-03-04 | 2001-02-13 | Neal R. Cutler | Use of cilostazol for treatment of sexual dysfunction |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US6257985B1 (en) * | 1999-10-01 | 2001-07-10 | Rexnord Corporation | Global shaft coupling |
| US6484565B2 (en) * | 1999-11-12 | 2002-11-26 | Drexel University | Single riser/single capillary viscometer using mass detection or column height detection |
| JP4159224B2 (ja) | 2000-02-29 | 2008-10-01 | 三洋電機株式会社 | 食器洗浄機 |
| US6458804B1 (en) * | 2001-01-26 | 2002-10-01 | R.T. Alamo Venturesi, Llc | Methods for the treatment of central nervous system disorders in certain patient groups |
| US6743806B2 (en) * | 2002-10-23 | 2004-06-01 | Otsuka Pharmaceutical Company, Limited | Active oxygen scavenger |
| TWI323660B (en) * | 2003-02-25 | 2010-04-21 | Otsuka Pharma Co Ltd | Pten inhibitor or maxi-k channels opener |
-
2004
- 2004-02-11 TW TW093103143A patent/TWI323660B/zh not_active IP Right Cessation
- 2004-02-17 MY MYPI20040511A patent/MY136863A/en unknown
- 2004-02-24 US US10/546,632 patent/US7825130B2/en not_active Expired - Fee Related
- 2004-02-24 JP JP2006502683A patent/JP4590397B2/ja not_active Expired - Fee Related
- 2004-02-24 KR KR1020057015646A patent/KR101031163B1/ko not_active Expired - Fee Related
- 2004-02-24 CN CN201010130082.3A patent/CN101829116B/zh not_active Expired - Fee Related
- 2004-02-24 ES ES04713984T patent/ES2276282T3/es not_active Expired - Lifetime
- 2004-02-24 EP EP04713984A patent/EP1599205B1/en not_active Expired - Lifetime
- 2004-02-24 WO PCT/JP2004/002146 patent/WO2004075897A1/en not_active Ceased
- 2004-02-24 MX MXPA05008996A patent/MXPA05008996A/es active IP Right Grant
- 2004-02-24 CA CA2515590A patent/CA2515590C/en not_active Expired - Fee Related
- 2004-02-24 CN CN2004800111403A patent/CN1780623B/zh not_active Expired - Fee Related
- 2004-02-24 DK DK04713984T patent/DK1599205T3/da active
- 2004-02-24 DE DE602004003348T patent/DE602004003348T2/de not_active Expired - Lifetime
- 2004-02-24 AU AU2004216340A patent/AU2004216340B9/en not_active Ceased
- 2004-02-24 AR ARP040100573A patent/AR043379A1/es unknown
- 2004-02-24 BR BRPI0407832-2A patent/BRPI0407832A/pt not_active IP Right Cessation
- 2004-02-24 AT AT04713984T patent/ATE345800T1/de active
- 2004-02-24 PT PT04713984T patent/PT1599205E/pt unknown
-
2006
- 2006-12-19 CY CY20061101814T patent/CY1106294T1/el unknown
-
2009
- 2009-12-30 US US12/650,275 patent/US8329731B2/en not_active Expired - Fee Related
-
2010
- 2010-08-12 JP JP2010180661A patent/JP5208172B2/ja not_active Expired - Lifetime
-
2012
- 2012-11-07 US US13/671,448 patent/US8653104B2/en not_active Expired - Fee Related
-
2013
- 2013-01-10 JP JP2013002314A patent/JP5566482B2/ja not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006518732A5 (https=) | ||
| US9452994B2 (en) | Manufacturing process for pyrimidine derivatives | |
| JP2020183410A5 (https=) | ||
| HUP0300030A2 (en) | Bupropion metabolites and methods of their synthesis and use and pharmaceutical compositions containing them and and their use | |
| EA016687B8 (ru) | Производные циклопропиламида | |
| RU2009138602A (ru) | Новые производные бензазепина | |
| TW200927096A (en) | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators | |
| JP2006503807A5 (https=) | ||
| JP2014524476A5 (https=) | ||
| JP2012508275A5 (https=) | ||
| NZ601088A (en) | Alpha 4 beta 2 neuronal nicotinic acetylcholine receptor ligands | |
| CN101460484A (zh) | 6-甲氧基-8-[4-(1-(5-氟)-喹啉-8-基-哌啶-4-基)-哌嗪-1-基]-喹啉盐酸盐 | |
| RU2007106930A (ru) | Производные хиназолина | |
| CA2515590A1 (en) | Pten inhibitor or maxi-k channels opener | |
| JP2004504308A5 (https=) | ||
| JP2006522023A5 (https=) | ||
| US20080045510A1 (en) | Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof | |
| JP2006500315A (ja) | 糖尿病状態に用いるヒスタミン−3受容体リガンド | |
| EP2961401B1 (en) | Methods of treating ototoxicity | |
| JP2019535715A5 (https=) | ||
| JP2008543813A5 (https=) | ||
| JP2007521272A5 (https=) | ||
| PL1778622T3 (pl) | Para-alkilo-podstawione amidy kwasu N-(hydroksy-3-metoksybenzylo)-cynamonowego i ich zastosowanie do wytwarzania środków leczniczych | |
| US20080119481A1 (en) | Crystalline forms of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline | |
| JP2006519251A5 (https=) |