JP2006518726A - Ｇ四重鎖ｄｎａ構造に極めて特異的に結合する化学誘導体、および、特異的な抗ガン剤としてのそれらの使用 - Google Patents
Ｇ四重鎖ｄｎａ構造に極めて特異的に結合する化学誘導体、および、特異的な抗ガン剤としてのそれらの使用 Download PDFInfo
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- JP2006518726A JP2006518726A JP2006502131A JP2006502131A JP2006518726A JP 2006518726 A JP2006518726 A JP 2006518726A JP 2006502131 A JP2006502131 A JP 2006502131A JP 2006502131 A JP2006502131 A JP 2006502131A JP 2006518726 A JP2006518726 A JP 2006518726A
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- methylquinolinio
- amido
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0301478A FR2850970B1 (fr) | 2003-02-07 | 2003-02-07 | Derives chimiques se liant de maniere tres specifique aux structures d'adn en g-quadruplexe et leur application comme agent anticancereux specifique |
| PCT/FR2004/000260 WO2004072027A2 (fr) | 2003-02-07 | 2004-02-05 | Derives chimiques se liant de maniere tres specifique aux structures d'adn en g-quadruplexe et leur application comme agent anticancereux specifique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006518726A true JP2006518726A (ja) | 2006-08-17 |
| JP2006518726A5 JP2006518726A5 (https=) | 2007-04-05 |
Family
ID=32731875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006502131A Pending JP2006518726A (ja) | 2003-02-07 | 2004-02-05 | Ｇ四重鎖ｄｎａ構造に極めて特異的に結合する化学誘導体、および、特異的な抗ガン剤としてのそれらの使用 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1603898A2 (https=) |
| JP (1) | JP2006518726A (https=) |
| AU (1) | AU2004210753A1 (https=) |
| BR (1) | BRPI0407320A (https=) |
| CA (1) | CA2514105A1 (https=) |
| FR (1) | FR2850970B1 (https=) |
| MX (1) | MXPA05007648A (https=) |
| WO (1) | WO2004072027A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8101357B2 (en) | 2009-04-09 | 2012-01-24 | Panasonic Corporation | Method for inhibiting telomerase reaction using an anionic phthalocyanine compound |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6887873B2 (en) | 2001-03-23 | 2005-05-03 | Aventis Pharma S.A. | Triazine derivatives and their application as antitelomerase agents |
| US8293716B2 (en) | 2005-05-26 | 2012-10-23 | Ramot At Tel Aviv University Ltd. | Method of treating cancer by modulation of mortalin |
| WO2008032324A2 (en) * | 2006-09-14 | 2008-03-20 | Ramot At Tel Aviv University Ltd. | Combination therapy for tumoral disease treatment |
| GB0706932D0 (en) * | 2007-04-10 | 2007-05-16 | Univ London Pharmacy | Ureylene derivatives |
| WO2009040819A2 (en) | 2007-09-25 | 2009-04-02 | Ramot At Tel Aviv University Ltd. | DOWN-REGULATION OF MORTALIN BY siRNA |
| CN101889210B (zh) | 2008-05-27 | 2014-12-10 | 松下电器产业株式会社 | G-quadruplex检测方法、形成G-quadruplex的DNA的检测方法以及端粒酶活性测定方法 |
| CN108066341B (zh) * | 2016-11-10 | 2020-10-30 | 中国科学院化学研究所 | 化合物在制备抗癌药物中的用途 |
| CN108066340B (zh) * | 2016-11-10 | 2020-10-27 | 中国科学院化学研究所 | 药物组合物 |
| WO2018211148A1 (en) * | 2017-05-19 | 2018-11-22 | Universite De Bretagne Occidentale | Bisquinolium derivatives for preventing or treating ebv-related cancers |
| CN113272294A (zh) * | 2018-08-24 | 2021-08-17 | 雅典学院生物医学研究基金会 | 2,6-双(((1h-苯并[d]咪唑-2-基)硫)甲基)吡啶和n2,n6-二苄基吡啶-2,6-二甲酰胺衍生物以及相关化合物作为磷酸肌醇3-激酶(pi3k)抑制剂用于治疗癌症 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001040218A1 (fr) * | 1999-11-29 | 2001-06-07 | Aventis Pharma S.A. | Derives arylamines et leur application comme agent antitelomerase |
| WO2002055515A1 (fr) * | 2001-01-09 | 2002-07-18 | Aventis Pharma S.A. | Derives chimiques et leur application comme agent antitelomerase |
| WO2002076975A1 (fr) * | 2001-03-23 | 2002-10-03 | Aventis Pharma S.A. | Derives chimiques et leur application comme agent antitelomerase |
| WO2002096903A2 (fr) * | 2001-05-28 | 2002-12-05 | Aventis Pharma S.A. | Derives chimiques et leur application comme agent antitelomerase |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2821355A1 (fr) * | 2001-02-23 | 2002-08-30 | Aventis Pharma Sa | Derives chimiques et leur application comme agent antitelomerase |
-
2003
- 2003-02-07 FR FR0301478A patent/FR2850970B1/fr not_active Expired - Fee Related
-
2004
- 2004-02-05 AU AU2004210753A patent/AU2004210753A1/en not_active Abandoned
- 2004-02-05 MX MXPA05007648A patent/MXPA05007648A/es not_active Application Discontinuation
- 2004-02-05 BR BRPI0407320-7A patent/BRPI0407320A/pt not_active IP Right Cessation
- 2004-02-05 WO PCT/FR2004/000260 patent/WO2004072027A2/fr not_active Ceased
- 2004-02-05 CA CA002514105A patent/CA2514105A1/fr not_active Abandoned
- 2004-02-05 JP JP2006502131A patent/JP2006518726A/ja active Pending
- 2004-02-05 EP EP04708378A patent/EP1603898A2/fr not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001040218A1 (fr) * | 1999-11-29 | 2001-06-07 | Aventis Pharma S.A. | Derives arylamines et leur application comme agent antitelomerase |
| WO2002055515A1 (fr) * | 2001-01-09 | 2002-07-18 | Aventis Pharma S.A. | Derives chimiques et leur application comme agent antitelomerase |
| WO2002076975A1 (fr) * | 2001-03-23 | 2002-10-03 | Aventis Pharma S.A. | Derives chimiques et leur application comme agent antitelomerase |
| WO2002096903A2 (fr) * | 2001-05-28 | 2002-12-05 | Aventis Pharma S.A. | Derives chimiques et leur application comme agent antitelomerase |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8101357B2 (en) | 2009-04-09 | 2012-01-24 | Panasonic Corporation | Method for inhibiting telomerase reaction using an anionic phthalocyanine compound |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2850970B1 (fr) | 2006-07-07 |
| WO2004072027A2 (fr) | 2004-08-26 |
| AU2004210753A1 (en) | 2004-08-26 |
| WO2004072027A3 (fr) | 2004-09-23 |
| EP1603898A2 (fr) | 2005-12-14 |
| BRPI0407320A (pt) | 2006-02-21 |
| FR2850970A1 (fr) | 2004-08-13 |
| CA2514105A1 (fr) | 2004-08-26 |
| MXPA05007648A (es) | 2006-12-15 |
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