AU2004210753A1 - Chemical derivatives binding very specifically with G-quadruplex DNA structures and use thereof as a specific anti-cancer agent - Google Patents
Chemical derivatives binding very specifically with G-quadruplex DNA structures and use thereof as a specific anti-cancer agent Download PDFInfo
- Publication number
- AU2004210753A1 AU2004210753A1 AU2004210753A AU2004210753A AU2004210753A1 AU 2004210753 A1 AU2004210753 A1 AU 2004210753A1 AU 2004210753 A AU2004210753 A AU 2004210753A AU 2004210753 A AU2004210753 A AU 2004210753A AU 2004210753 A1 AU2004210753 A1 AU 2004210753A1
- Authority
- AU
- Australia
- Prior art keywords
- amido
- formula
- products
- methylquinolinio
- pyridinedicarboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 239000002246 antineoplastic agent Substances 0.000 title claims description 5
- 108091081406 G-quadruplex Proteins 0.000 title description 25
- 239000000126 substance Substances 0.000 title description 3
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- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 28
- 239000003795 chemical substances by application Substances 0.000 claims description 26
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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Landscapes
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- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR03/01478 | 2003-02-07 | ||
| FR0301478A FR2850970B1 (fr) | 2003-02-07 | 2003-02-07 | Derives chimiques se liant de maniere tres specifique aux structures d'adn en g-quadruplexe et leur application comme agent anticancereux specifique |
| PCT/FR2004/000260 WO2004072027A2 (fr) | 2003-02-07 | 2004-02-05 | Derives chimiques se liant de maniere tres specifique aux structures d'adn en g-quadruplexe et leur application comme agent anticancereux specifique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004210753A1 true AU2004210753A1 (en) | 2004-08-26 |
Family
ID=32731875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004210753A Abandoned AU2004210753A1 (en) | 2003-02-07 | 2004-02-05 | Chemical derivatives binding very specifically with G-quadruplex DNA structures and use thereof as a specific anti-cancer agent |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1603898A2 (https=) |
| JP (1) | JP2006518726A (https=) |
| AU (1) | AU2004210753A1 (https=) |
| BR (1) | BRPI0407320A (https=) |
| CA (1) | CA2514105A1 (https=) |
| FR (1) | FR2850970B1 (https=) |
| MX (1) | MXPA05007648A (https=) |
| WO (1) | WO2004072027A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6887873B2 (en) | 2001-03-23 | 2005-05-03 | Aventis Pharma S.A. | Triazine derivatives and their application as antitelomerase agents |
| US8293716B2 (en) | 2005-05-26 | 2012-10-23 | Ramot At Tel Aviv University Ltd. | Method of treating cancer by modulation of mortalin |
| WO2008032324A2 (en) * | 2006-09-14 | 2008-03-20 | Ramot At Tel Aviv University Ltd. | Combination therapy for tumoral disease treatment |
| GB0706932D0 (en) * | 2007-04-10 | 2007-05-16 | Univ London Pharmacy | Ureylene derivatives |
| WO2009040819A2 (en) | 2007-09-25 | 2009-04-02 | Ramot At Tel Aviv University Ltd. | DOWN-REGULATION OF MORTALIN BY siRNA |
| CN101889210B (zh) | 2008-05-27 | 2014-12-10 | 松下电器产业株式会社 | G-quadruplex检测方法、形成G-quadruplex的DNA的检测方法以及端粒酶活性测定方法 |
| JP4510929B1 (ja) | 2009-04-09 | 2010-07-28 | パナソニック株式会社 | テロメラーゼ反応阻害方法およびそれに用いられるテロメラーゼ反応阻害剤 |
| CN108066341B (zh) * | 2016-11-10 | 2020-10-30 | 中国科学院化学研究所 | 化合物在制备抗癌药物中的用途 |
| CN108066340B (zh) * | 2016-11-10 | 2020-10-27 | 中国科学院化学研究所 | 药物组合物 |
| WO2018211148A1 (en) * | 2017-05-19 | 2018-11-22 | Universite De Bretagne Occidentale | Bisquinolium derivatives for preventing or treating ebv-related cancers |
| CN113272294A (zh) * | 2018-08-24 | 2021-08-17 | 雅典学院生物医学研究基金会 | 2,6-双(((1h-苯并[d]咪唑-2-基)硫)甲基)吡啶和n2,n6-二苄基吡啶-2,6-二甲酰胺衍生物以及相关化合物作为磷酸肌醇3-激酶(pi3k)抑制剂用于治疗癌症 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK7402002A3 (en) * | 1999-11-29 | 2002-11-06 | Aventis Pharma Sa | Arylamine derivatives and their use as anti-telomerase agent |
| FR2819255B1 (fr) * | 2001-01-09 | 2003-02-28 | Aventis Pharma Sa | Derives chimiques et leur application comme agent antitelomerase |
| FR2821355A1 (fr) * | 2001-02-23 | 2002-08-30 | Aventis Pharma Sa | Derives chimiques et leur application comme agent antitelomerase |
| CO5380035A1 (es) * | 2001-03-23 | 2004-03-31 | Aventis Pharma Sa | Derivados quimicos y su aplicacion como agente antitelomerasa |
| WO2002096903A2 (fr) * | 2001-05-28 | 2002-12-05 | Aventis Pharma S.A. | Derives chimiques et leur application comme agent antitelomerase |
-
2003
- 2003-02-07 FR FR0301478A patent/FR2850970B1/fr not_active Expired - Fee Related
-
2004
- 2004-02-05 AU AU2004210753A patent/AU2004210753A1/en not_active Abandoned
- 2004-02-05 MX MXPA05007648A patent/MXPA05007648A/es not_active Application Discontinuation
- 2004-02-05 BR BRPI0407320-7A patent/BRPI0407320A/pt not_active IP Right Cessation
- 2004-02-05 WO PCT/FR2004/000260 patent/WO2004072027A2/fr not_active Ceased
- 2004-02-05 CA CA002514105A patent/CA2514105A1/fr not_active Abandoned
- 2004-02-05 JP JP2006502131A patent/JP2006518726A/ja active Pending
- 2004-02-05 EP EP04708378A patent/EP1603898A2/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| FR2850970B1 (fr) | 2006-07-07 |
| WO2004072027A2 (fr) | 2004-08-26 |
| WO2004072027A3 (fr) | 2004-09-23 |
| JP2006518726A (ja) | 2006-08-17 |
| EP1603898A2 (fr) | 2005-12-14 |
| BRPI0407320A (pt) | 2006-02-21 |
| FR2850970A1 (fr) | 2004-08-13 |
| CA2514105A1 (fr) | 2004-08-26 |
| MXPA05007648A (es) | 2006-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |