JP2006515358A5 - - Google Patents
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- Publication number
- JP2006515358A5 JP2006515358A5 JP2006500252A JP2006500252A JP2006515358A5 JP 2006515358 A5 JP2006515358 A5 JP 2006515358A5 JP 2006500252 A JP2006500252 A JP 2006500252A JP 2006500252 A JP2006500252 A JP 2006500252A JP 2006515358 A5 JP2006515358 A5 JP 2006515358A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- group
- sulfonic
- pka
- phosphonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical group OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 125000000542 sulfonic acid group Chemical group 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03250868 | 2003-02-12 | ||
| EP03250868.1 | 2003-02-12 | ||
| GB0305322.0 | 2003-03-07 | ||
| GB0305322A GB0305322D0 (en) | 2003-03-07 | 2003-03-07 | Chemoembolisation |
| PCT/GB2004/000548 WO2004071495A1 (en) | 2003-02-12 | 2004-02-12 | Composition for chemoembolotherapy of solid tumors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011034961A Division JP5616251B2 (ja) | 2003-02-12 | 2011-02-21 | 固形腫瘍の化学的塞栓療法用組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006515358A JP2006515358A (ja) | 2006-05-25 |
| JP2006515358A5 true JP2006515358A5 (https=) | 2011-04-14 |
| JP4895802B2 JP4895802B2 (ja) | 2012-03-14 |
Family
ID=32870779
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500252A Expired - Lifetime JP4895802B2 (ja) | 2003-02-12 | 2004-02-12 | 固形腫瘍の化学的塞栓療法用組成物 |
| JP2011034961A Expired - Lifetime JP5616251B2 (ja) | 2003-02-12 | 2011-02-21 | 固形腫瘍の化学的塞栓療法用組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011034961A Expired - Lifetime JP5616251B2 (ja) | 2003-02-12 | 2011-02-21 | 固形腫瘍の化学的塞栓療法用組成物 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1592405B1 (https=) |
| JP (2) | JP4895802B2 (https=) |
| KR (1) | KR101157260B1 (https=) |
| CN (4) | CN102895662B (https=) |
| AT (1) | ATE396708T1 (https=) |
| DE (1) | DE602004014101D1 (https=) |
| ES (1) | ES2308149T3 (https=) |
| HK (1) | HK1079980B (https=) |
| WO (1) | WO2004071495A1 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE01918975T1 (de) | 2000-03-24 | 2006-04-13 | Biosphere Medical, Inc., Rockland | Mikrokügelchen zur aktiven Embolisierung |
| WO2005087193A2 (en) * | 2004-03-11 | 2005-09-22 | Biocompatibles Uk Limited | Chemoembolisation involving an anthracycline compound |
| EP3085361A1 (en) * | 2004-09-07 | 2016-10-26 | Biocompatibles UK Limited | Compositions comprising camptothecins in microspheres |
| KR20140090270A (ko) * | 2005-05-09 | 2014-07-16 | 바이오스피어 메디칼 에스.에이. | 마이크로스피어 및 비이온성 조영제를 사용하는 조성물 및 방법 |
| US20080305176A1 (en) * | 2006-01-24 | 2008-12-11 | Biocompatibles Uk Limited | Process For Loading Polymer Particles With Drug |
| WO2007090127A2 (en) | 2006-01-30 | 2007-08-09 | Surgica Corporation | Compressible intravascular embolization particles and related methods and delivery systems |
| EP2034951B2 (en) | 2006-06-22 | 2020-03-25 | Biocompatibles UK Limited | Rehydratable pharmaceutical product |
| EP1985286A1 (en) | 2007-04-24 | 2008-10-29 | Biocompatibles UK Limited | Microspheres for treatment of brain tumours |
| JP5302300B2 (ja) * | 2007-05-11 | 2013-10-02 | ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ | アンスラサイクリンの医薬組成物 |
| WO2009022190A1 (en) * | 2007-08-16 | 2009-02-19 | Biocompatibles Uk Limited | Delivery of drug combinations |
| EP3181123A1 (en) | 2008-12-02 | 2017-06-21 | Biocompatibles Uk Ltd. | Pancreatic tumour treatment |
| GB201101429D0 (en) * | 2011-01-27 | 2011-03-16 | Biocompatibles Uk Ltd | Drug delivery system |
| US20150224221A1 (en) | 2012-08-31 | 2015-08-13 | Chung-Ang University Industry-Academic Cooperation Foundation | Method for preparing microspheres for emboli, and method for preparing microspheres to which drug-containing carrier is bound |
| JP6420817B2 (ja) * | 2013-03-15 | 2018-11-07 | バイオコンパティブルズ ユーケー リミテッド | 結像可能な塞栓性微小球 |
| GB2519738A (en) | 2013-09-06 | 2015-05-06 | Biocompatibles Uk Ltd | Radiopaque polymers |
| GB2521997A (en) | 2013-09-06 | 2015-07-15 | Biocompatibles Uk Ltd | Radiopaque polymers |
| PL3264997T3 (pl) | 2015-03-02 | 2019-07-31 | Accurate Medical Therapeutics Ltd. | Cewniki z otworami bocznymi do modyfikowania i podawania zawiesin pacjentowi |
| GB201515602D0 (en) | 2015-09-03 | 2015-10-21 | Biocompatibles Uk Ltd | Polymers and microspheres |
| CN115137870B (zh) | 2016-03-14 | 2024-05-10 | 生物相容性英国公司 | 包含颗粒的乳液 |
| JP6921116B2 (ja) | 2016-05-04 | 2021-08-18 | アキュレイト メディカル セラピューティクス リミテッド | スリットパターンを有する塞栓マイクロカテーテルヘッド |
| US11382990B2 (en) | 2016-11-16 | 2022-07-12 | The Usa, As Represented By The Secretary, Dhhs | Imageable polymers, methods of making and methods of use thereof |
| CN116173284B (zh) * | 2017-07-13 | 2025-09-19 | 瓦里安医疗系统公司 | 栓塞微球 |
| JP7364193B2 (ja) | 2017-11-02 | 2023-10-18 | アキュレイト メディカル セラピューティクス リミテッド | 内蔵フィルタを有する塞栓術用カテーテル |
| TW202000189A (zh) | 2018-06-29 | 2020-01-01 | 英商白康帝英國有限公司 | 不透射線聚合物 |
| CN113727699A (zh) | 2019-03-22 | 2021-11-30 | 生物相容英国有限公司 | 栓塞微球和方法 |
| WO2020234889A1 (en) | 2019-05-23 | 2020-11-26 | Accurate Medical Therapeutics Ltd. | Embolization catheter for reflux free delivery of microspheres |
| GB201910286D0 (en) | 2019-07-18 | 2019-09-04 | Biocompatibles Uk Ltd | Radiopaque polymers |
| AU2021227230A1 (en) * | 2020-02-25 | 2022-09-08 | Hepion Pharmaceuticals, Inc. | Use of cyclosporine analogues for treating cancer |
| CN114099442B (zh) * | 2020-08-25 | 2024-01-30 | 复旦大学 | 用于肿瘤放化疗栓塞治疗和影像的多功能微球制剂及其制备方法 |
| CN113797383A (zh) * | 2021-09-28 | 2021-12-17 | 迪格瑞医疗科技(苏州)有限公司 | 一种高弹性、高载药量的栓塞微球及其制备方法 |
| CN118434411A (zh) | 2021-12-23 | 2024-08-02 | 波士顿科学医疗设备有限公司 | 化学栓塞组合物及其治疗方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4978713A (en) * | 1987-12-16 | 1990-12-18 | Ciba-Geigy Corporation | Polyvinyl alcohol derivatives containing pendant vinylic monomer reaction product units bound through ether groups and hydrogel contact lenses made therefrom |
| JP3041627B2 (ja) * | 1989-04-13 | 2000-05-15 | 武田薬品工業株式会社 | アントラサイクリン系抗生物質の安定組成物 |
| JPH06329542A (ja) * | 1993-05-21 | 1994-11-29 | Kibun Food Chemifa Co Ltd | 不溶性アルギン酸塩粒子を含む局所血管止血用組成物および動脈化学塞栓用組成物 |
| DE69432867T2 (de) * | 1993-11-18 | 2004-04-22 | Sirtex Medical Ltd., Burswood | Zubereitung mit gesteuerter freisetzung |
| WO1999012577A1 (en) * | 1997-09-05 | 1999-03-18 | Nycomed Imaging As | Polymer particles made of polyvinyl alcohol and comprising a contrast agent for chemoembolization |
| EP1263803B1 (en) * | 2000-03-13 | 2007-09-19 | BioCure, Inc. | Embolic compositions |
| AU2001292092A1 (en) * | 2000-10-06 | 2002-04-15 | Biocompatibles Uk Limited | Zwitterionic polymers |
| US20060165804A1 (en) * | 2002-09-25 | 2006-07-27 | Lewis Andrew L | Polymer compositions for administration to animals |
-
2004
- 2004-02-12 HK HK05112166.8A patent/HK1079980B/en not_active IP Right Cessation
- 2004-02-12 KR KR1020057014847A patent/KR101157260B1/ko not_active Expired - Fee Related
- 2004-02-12 CN CN201210299592.2A patent/CN102895662B/zh not_active Expired - Lifetime
- 2004-02-12 EP EP04710431A patent/EP1592405B1/en not_active Expired - Lifetime
- 2004-02-12 DE DE602004014101T patent/DE602004014101D1/de not_active Expired - Lifetime
- 2004-02-12 ES ES04710431T patent/ES2308149T3/es not_active Expired - Lifetime
- 2004-02-12 JP JP2006500252A patent/JP4895802B2/ja not_active Expired - Lifetime
- 2004-02-12 CN CN201410044028.5A patent/CN103908704B/zh not_active Expired - Lifetime
- 2004-02-12 AT AT04710431T patent/ATE396708T1/de not_active IP Right Cessation
- 2004-02-12 CN CN201310320841.6A patent/CN103393605B/zh not_active Expired - Lifetime
- 2004-02-12 WO PCT/GB2004/000548 patent/WO2004071495A1/en not_active Ceased
- 2004-02-12 CN CN201610844279.0A patent/CN106267325B/zh not_active Expired - Lifetime
-
2011
- 2011-02-21 JP JP2011034961A patent/JP5616251B2/ja not_active Expired - Lifetime
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