JP2006514705A5 - - Google Patents
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- JP2006514705A5 JP2006514705A5 JP2004551944A JP2004551944A JP2006514705A5 JP 2006514705 A5 JP2006514705 A5 JP 2006514705A5 JP 2004551944 A JP2004551944 A JP 2004551944A JP 2004551944 A JP2004551944 A JP 2004551944A JP 2006514705 A5 JP2006514705 A5 JP 2006514705A5
- Authority
- JP
- Japan
- Prior art keywords
- shape
- liquid
- absorbed
- retaining
- aggregate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 239000007788 liquid Substances 0.000 claims description 61
- 239000002245 particle Substances 0.000 claims description 36
- 239000000017 hydrogel Substances 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 32
- 239000000126 substance Substances 0.000 claims description 23
- 239000000178 monomer Substances 0.000 claims description 21
- 239000000556 agonist Substances 0.000 claims description 7
- 238000006116 polymerization reaction Methods 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 15
- XFCMNSHQOZQILR-UHFFFAOYSA-N 2-[2-(2-methylprop-2-enoyloxy)ethoxy]ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCOC(=O)C(C)=C XFCMNSHQOZQILR-UHFFFAOYSA-N 0.000 claims 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 12
- 125000000217 alkyl group Chemical group 0.000 claims 12
- -1 hydroxy tricarboxylic acid Chemical class 0.000 claims 12
- KMZHZAAOEWVPSE-UHFFFAOYSA-N 2,3-dihydroxypropyl acetate Chemical compound CC(=O)OCC(O)CO KMZHZAAOEWVPSE-UHFFFAOYSA-N 0.000 claims 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 9
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 9
- 125000003545 alkoxy group Chemical group 0.000 claims 9
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims 9
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 9
- 229920005862 polyol Polymers 0.000 claims 9
- 150000003077 polyols Chemical class 0.000 claims 9
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 claims 6
- LEJBBGNFPAFPKQ-UHFFFAOYSA-N 2-(2-prop-2-enoyloxyethoxy)ethyl prop-2-enoate Chemical compound C=CC(=O)OCCOCCOC(=O)C=C LEJBBGNFPAFPKQ-UHFFFAOYSA-N 0.000 claims 6
- XNWFRZJHXBZDAG-UHFFFAOYSA-N 2-METHOXYETHANOL Chemical compound COCCO XNWFRZJHXBZDAG-UHFFFAOYSA-N 0.000 claims 6
- KUDUQBURMYMBIJ-UHFFFAOYSA-N 2-prop-2-enoyloxyethyl prop-2-enoate Chemical group C=CC(=O)OCCOC(=O)C=C KUDUQBURMYMBIJ-UHFFFAOYSA-N 0.000 claims 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 6
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 6
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 claims 6
- 235000011187 glycerol Nutrition 0.000 claims 6
- VOZRXNHHFUQHIL-UHFFFAOYSA-N glycidyl methacrylate Chemical compound CC(=C)C(=O)OCC1CO1 VOZRXNHHFUQHIL-UHFFFAOYSA-N 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 239000003431 cross linking reagent Substances 0.000 claims 5
- 230000033444 hydroxylation Effects 0.000 claims 5
- 238000005805 hydroxylation reaction Methods 0.000 claims 5
- GNSFRPWPOGYVLO-UHFFFAOYSA-N 3-hydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCO GNSFRPWPOGYVLO-UHFFFAOYSA-N 0.000 claims 4
- 239000004971 Cross linker Substances 0.000 claims 4
- 239000001124 (E)-prop-1-ene-1,2,3-tricarboxylic acid Substances 0.000 claims 3
- ARXJGSRGQADJSQ-UHFFFAOYSA-N 1-methoxypropan-2-ol Chemical compound COCC(C)O ARXJGSRGQADJSQ-UHFFFAOYSA-N 0.000 claims 3
- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 claims 3
- OLQFXOWPTQTLDP-UHFFFAOYSA-N 2-(2-hydroxyethoxy)ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCO OLQFXOWPTQTLDP-UHFFFAOYSA-N 0.000 claims 3
- RWXMAAYKJDQVTF-UHFFFAOYSA-N 2-(2-hydroxyethoxy)ethyl prop-2-enoate Chemical compound OCCOCCOC(=O)C=C RWXMAAYKJDQVTF-UHFFFAOYSA-N 0.000 claims 3
- ZKLMKZINKNMVKA-UHFFFAOYSA-N 2-(2-hydroxypropoxy)propan-1-ol;2-methylprop-2-enoic acid Chemical compound CC(=C)C(O)=O.CC(O)COC(C)CO ZKLMKZINKNMVKA-UHFFFAOYSA-N 0.000 claims 3
- YATYDCQGPUOZGZ-UHFFFAOYSA-N 2-(2-hydroxypropoxy)propan-1-ol;prop-2-enoic acid Chemical compound OC(=O)C=C.CC(O)COC(C)CO YATYDCQGPUOZGZ-UHFFFAOYSA-N 0.000 claims 3
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 3
- JJBFVQSGPLGDNX-UHFFFAOYSA-N 2-(2-methylprop-2-enoyloxy)propyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC(C)COC(=O)C(C)=C JJBFVQSGPLGDNX-UHFFFAOYSA-N 0.000 claims 3
- IPDYIFGHKYLTOM-UHFFFAOYSA-N 2-(2-prop-2-enoyloxypropoxy)propyl prop-2-enoate Chemical compound C=CC(=O)OCC(C)OCC(C)OC(=O)C=C IPDYIFGHKYLTOM-UHFFFAOYSA-N 0.000 claims 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 3
- JFZBUNLOTDDXNY-UHFFFAOYSA-N 2-[2-(2-methylprop-2-enoyloxy)propoxy]propyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(C)OCC(C)OC(=O)C(C)=C JFZBUNLOTDDXNY-UHFFFAOYSA-N 0.000 claims 3
- ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical compound CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 claims 3
- HXDLWJWIAHWIKI-UHFFFAOYSA-N 2-hydroxyethyl acetate Chemical compound CC(=O)OCCO HXDLWJWIAHWIKI-UHFFFAOYSA-N 0.000 claims 3
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 3
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims 3
- VHSHLMUCYSAUQU-UHFFFAOYSA-N 2-hydroxypropyl methacrylate Chemical compound CC(O)COC(=O)C(C)=C VHSHLMUCYSAUQU-UHFFFAOYSA-N 0.000 claims 3
- GWZMWHWAWHPNHN-UHFFFAOYSA-N 2-hydroxypropyl prop-2-enoate Chemical compound CC(O)COC(=O)C=C GWZMWHWAWHPNHN-UHFFFAOYSA-N 0.000 claims 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims 3
- QZPSOSOOLFHYRR-UHFFFAOYSA-N 3-hydroxypropyl prop-2-enoate Chemical compound OCCCOC(=O)C=C QZPSOSOOLFHYRR-UHFFFAOYSA-N 0.000 claims 3
- DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical compound FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 claims 3
- 239000004593 Epoxy Substances 0.000 claims 3
- UXDDRFCJKNROTO-UHFFFAOYSA-N Glycerol 1,2-diacetate Chemical compound CC(=O)OCC(CO)OC(C)=O UXDDRFCJKNROTO-UHFFFAOYSA-N 0.000 claims 3
- 239000004348 Glyceryl diacetate Substances 0.000 claims 3
- 239000004347 Glyceryl monoacetate Substances 0.000 claims 3
- 229920000877 Melamine resin Polymers 0.000 claims 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- OKKRPWIIYQTPQF-UHFFFAOYSA-N Trimethylolpropane trimethacrylate Chemical compound CC(=C)C(=O)OCC(CC)(COC(=O)C(C)=C)COC(=O)C(C)=C OKKRPWIIYQTPQF-UHFFFAOYSA-N 0.000 claims 3
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical compound C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 3
- 229940091181 aconitic acid Drugs 0.000 claims 3
- 125000005907 alkyl ester group Chemical group 0.000 claims 3
- 150000005215 alkyl ethers Chemical class 0.000 claims 3
- 229940061720 alpha hydroxy acid Drugs 0.000 claims 3
- KGDPCYLOLUTZEO-UHFFFAOYSA-N bis(2-hydroxyethyl) 2-methylidenebutanedioate Chemical compound OCCOC(=O)CC(=C)C(=O)OCCO KGDPCYLOLUTZEO-UHFFFAOYSA-N 0.000 claims 3
- DWSNCSCTZIYPNV-UHFFFAOYSA-N bis(3-hydroxypropyl) oxalate Chemical compound OCCCOC(=O)C(=O)OCCCO DWSNCSCTZIYPNV-UHFFFAOYSA-N 0.000 claims 3
- BFHRUCFCIXWADD-UHFFFAOYSA-N bis(ethenyl) 2,3-dihydroxybutanedioate Chemical compound C=COC(=O)C(O)C(O)C(=O)OC=C BFHRUCFCIXWADD-UHFFFAOYSA-N 0.000 claims 3
- ZPOLOEWJWXZUSP-AATRIKPKSA-N bis(prop-2-enyl) (e)-but-2-enedioate Chemical compound C=CCOC(=O)\C=C\C(=O)OCC=C ZPOLOEWJWXZUSP-AATRIKPKSA-N 0.000 claims 3
- ZPOLOEWJWXZUSP-WAYWQWQTSA-N bis(prop-2-enyl) (z)-but-2-enedioate Chemical compound C=CCOC(=O)\C=C/C(=O)OCC=C ZPOLOEWJWXZUSP-WAYWQWQTSA-N 0.000 claims 3
- VPPSHXIFIAJKMX-UHFFFAOYSA-N bis(prop-2-enyl) 2,3-dihydroxybutanedioate Chemical compound C=CCOC(=O)C(O)C(O)C(=O)OCC=C VPPSHXIFIAJKMX-UHFFFAOYSA-N 0.000 claims 3
- YLTDNYQTDYMOBH-UHFFFAOYSA-N bis(prop-2-enyl) 2-hydroxybutanedioate Chemical compound C=CCOC(=O)C(O)CC(=O)OCC=C YLTDNYQTDYMOBH-UHFFFAOYSA-N 0.000 claims 3
- PRXKHZGEIIFEBU-UHFFFAOYSA-N butane-1,4-diol;2-methylprop-2-enoic acid Chemical compound CC(=C)C(O)=O.CC(=C)C(O)=O.OCCCCO PRXKHZGEIIFEBU-UHFFFAOYSA-N 0.000 claims 3
- OWBTYPJTUOEWEK-UHFFFAOYSA-N butane-2,3-diol Chemical compound CC(O)C(C)O OWBTYPJTUOEWEK-UHFFFAOYSA-N 0.000 claims 3
- GTZCVFVGUGFEME-IWQZZHSRSA-N cis-aconitic acid Chemical compound OC(=O)C\C(C(O)=O)=C\C(O)=O GTZCVFVGUGFEME-IWQZZHSRSA-N 0.000 claims 3
- 229920006037 cross link polymer Polymers 0.000 claims 3
- 150000001991 dicarboxylic acids Chemical class 0.000 claims 3
- VVYDVQWJZWRVPE-UHFFFAOYSA-L dimethyltin(2+);diiodide Chemical compound C[Sn](C)(I)I VVYDVQWJZWRVPE-UHFFFAOYSA-L 0.000 claims 3
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims 3
- 150000002148 esters Chemical class 0.000 claims 3
- 125000001033 ether group Chemical group 0.000 claims 3
- STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Substances CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 claims 3
- 235000019443 glyceryl diacetate Nutrition 0.000 claims 3
- 235000019442 glyceryl monoacetate Nutrition 0.000 claims 3
- XXMIOPMDWAUFGU-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO XXMIOPMDWAUFGU-UHFFFAOYSA-N 0.000 claims 3
- OHMBHFSEKCCCBW-UHFFFAOYSA-N hexane-2,5-diol Chemical compound CC(O)CCC(C)O OHMBHFSEKCCCBW-UHFFFAOYSA-N 0.000 claims 3
- JDSHMPZPIAZGSV-UHFFFAOYSA-N melamine Chemical compound NC1=NC(N)=NC(N)=N1 JDSHMPZPIAZGSV-UHFFFAOYSA-N 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- RIEABXYBQSLTFR-UHFFFAOYSA-N monobutyrin Chemical compound CCCC(=O)OCC(O)CO RIEABXYBQSLTFR-UHFFFAOYSA-N 0.000 claims 3
- 150000002763 monocarboxylic acids Chemical class 0.000 claims 3
- ZIUHHBKFKCYYJD-UHFFFAOYSA-N n,n'-methylenebisacrylamide Chemical compound C=CC(=O)NCNC(=O)C=C ZIUHHBKFKCYYJD-UHFFFAOYSA-N 0.000 claims 3
- RPQRDASANLAFCM-UHFFFAOYSA-N oxiran-2-ylmethyl prop-2-enoate Chemical compound C=CC(=O)OCC1CO1 RPQRDASANLAFCM-UHFFFAOYSA-N 0.000 claims 3
- DBSDMAPJGHBWAL-UHFFFAOYSA-N penta-1,4-dien-3-ylbenzene Chemical compound C=CC(C=C)C1=CC=CC=C1 DBSDMAPJGHBWAL-UHFFFAOYSA-N 0.000 claims 3
- 229920001515 polyalkylene glycol Polymers 0.000 claims 3
- 229920001223 polyethylene glycol Polymers 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 230000000379 polymerizing effect Effects 0.000 claims 3
- GTZCVFVGUGFEME-UHFFFAOYSA-N trans-aconitic acid Natural products OC(=O)CC(C(O)=O)=CC(O)=O GTZCVFVGUGFEME-UHFFFAOYSA-N 0.000 claims 3
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 claims 3
- XHDRYKHQTDSTRY-UHFFFAOYSA-N tris(2-hydroxyethyl) 2-hydroxypropane-1,2,3-tricarboxylate Chemical compound OCCOC(=O)CC(O)(C(=O)OCCO)CC(=O)OCCO XHDRYKHQTDSTRY-UHFFFAOYSA-N 0.000 claims 3
- KJWHEZXBZQXVSA-UHFFFAOYSA-N tris(prop-2-enyl) phosphite Chemical compound C=CCOP(OCC=C)OCC=C KJWHEZXBZQXVSA-UHFFFAOYSA-N 0.000 claims 3
- 229960000834 vinyl ether Drugs 0.000 claims 3
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 3
- 229920002554 vinyl polymer Polymers 0.000 claims 3
- GVVKAJCGFRGPFD-ALCCZGGFSA-N (Z)-2-penta-1,4-dien-3-ylbut-2-enedioic acid Chemical compound OC(=O)\C=C(C(O)=O)\C(C=C)C=C GVVKAJCGFRGPFD-ALCCZGGFSA-N 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 150000002739 metals Chemical class 0.000 claims 2
- NHARPDSAXCBDDR-UHFFFAOYSA-N propyl 2-methylprop-2-enoate Chemical compound CCCOC(=O)C(C)=C NHARPDSAXCBDDR-UHFFFAOYSA-N 0.000 claims 2
- 239000004065 semiconductor Substances 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 239000000956 alloy Substances 0.000 claims 1
- 229910045601 alloy Inorganic materials 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229940018560 citraconate Drugs 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 208000029078 coronary artery disease Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000003647 oxidation Effects 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 208000023504 respiratory system disease Diseases 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- KAKZBPTYRLMSJV-UHFFFAOYSA-N vinyl-ethylene Natural products C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 claims 1
- 239000008207 working material Substances 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/289,756 US7351430B2 (en) | 2002-11-06 | 2002-11-06 | Shape-retentive hydrogel particle aggregates and their uses |
| PCT/US2003/035671 WO2004043438A1 (en) | 2002-11-06 | 2003-11-06 | Shape-retentive hydrogel particle aggregates and their uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514705A JP2006514705A (ja) | 2006-05-11 |
| JP2006514705A5 true JP2006514705A5 (enExample) | 2008-05-22 |
Family
ID=32176104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004551944A Ceased JP2006514705A (ja) | 2002-11-06 | 2003-11-06 | 形状維持性ヒドロゲル粒子凝集体およびその使用法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7351430B2 (enExample) |
| EP (2) | EP1567132A4 (enExample) |
| JP (1) | JP2006514705A (enExample) |
| AU (1) | AU2003295428C1 (enExample) |
| CA (1) | CA2512033A1 (enExample) |
| NZ (1) | NZ540571A (enExample) |
| WO (1) | WO2004043438A1 (enExample) |
| ZA (1) | ZA200504624B (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005517802A (ja) * | 2002-02-15 | 2005-06-16 | ゼットエムエス エルエルシー | 生物医学用途のための重合方法および材料 |
| US7351430B2 (en) * | 2002-11-06 | 2008-04-01 | Uluru Inc. | Shape-retentive hydrogel particle aggregates and their uses |
| US7811605B2 (en) * | 2002-11-06 | 2010-10-12 | Uluru Inc. | Method of formation of shape-retentive aggregates of gel particles and their uses |
| US20050196343A1 (en) * | 2004-02-27 | 2005-09-08 | Molecular Therapeutics, Inc. | Degradable nanoparticles |
| US8663225B2 (en) | 2004-11-12 | 2014-03-04 | Medtronic, Inc. | Hydrogel bone void filler |
| US20060193894A1 (en) * | 2005-02-28 | 2006-08-31 | Jen James S | Methods for providing biomedical devices with hydrophilic antimicrobial coatings |
| CA2627288C (en) * | 2005-10-26 | 2015-12-15 | Jan-Eric W. Ahlfors | Acellular bioabsorbable tissue regeneration matrices produced by incubating acellular blood products |
| EP1780544B1 (en) * | 2005-11-01 | 2009-12-09 | JSR Corporation | Magnetic particles for diagnostics |
| US7910135B2 (en) * | 2006-10-13 | 2011-03-22 | Uluru Inc. | Hydrogel wound dressing and biomaterials formed in situ and their uses |
| US20080228268A1 (en) * | 2007-03-15 | 2008-09-18 | Uluru, Inc. | Method of Formation of Viscous, Shape Conforming Gels and Their Uses as Medical Prosthesis |
| JP2011500898A (ja) * | 2007-10-10 | 2011-01-06 | ベンズ リサーチ アンド ディベロップメント コーポレーション | 高い含水率および安定性を有するヒドロゲル |
| US20110009520A1 (en) * | 2008-03-20 | 2011-01-13 | Figuly Garret D | Dimensionally stable, shaped articles comprised of dried, aggregated, water-swellable hydrogel microspheres and method of making same |
| WO2010002824A1 (en) | 2008-06-30 | 2010-01-07 | Allergan, Inc. | Fillable prosthetic implant with gel-like properties |
| ES2335958B2 (es) * | 2008-08-06 | 2010-11-02 | Universidad De Santiago De Compostela | Hidrogeles acrilicos con ciclodextrinas colgantes, su preparacion y su aplicacion como sistemas de liberacion y componentes de lentes de contacto. |
| JP2012235797A (ja) * | 2009-09-18 | 2012-12-06 | Terumo Corp | ステント |
| AU2010314994B2 (en) | 2009-11-09 | 2016-10-06 | Spotlight Technology Partners Llc | Fragmented hydrogels |
| JP5864429B2 (ja) | 2009-11-09 | 2016-02-17 | スポットライト テクノロジー パートナーズ エルエルシーＳｐｏｔｌｉｇｈｔ Ｔｅｃｈｎｏｌｏｇｙ Ｐａｒｔｎｅｒｓ Ｌｌｃ | 架橋ヒドロゲル組成物、ヒドロゲル組成物の形成方法、及びキット |
| WO2011066441A1 (en) * | 2009-11-25 | 2011-06-03 | Healionics Corporation | Implantable medical devices having microporous surface layers and method for reducing foreign body response to the same |
| CA2781518C (en) | 2009-11-25 | 2016-08-23 | Healionics Corporation | Granules of porous biocompatible materials |
| EP3960215B1 (en) | 2009-12-15 | 2024-10-16 | Incept, LLC | Implants and biodegradable fiducial markers |
| KR101813300B1 (ko) | 2010-04-08 | 2017-12-28 | 힐리오닉스 코포레이션 | 미세다공성 표면 층을 가지는 이식형 의료 장치 및 이에 대한 이물 반응을 감소시키는 방법 |
| GB201110042D0 (en) * | 2011-06-14 | 2011-07-27 | Univ Edinburgh | Growth of cells |
| US8883503B2 (en) * | 2011-06-23 | 2014-11-11 | Indian Institute Of Technology Kanpur | Hydrogel scaffolds for tissue engineering |
| US9205150B2 (en) | 2011-12-05 | 2015-12-08 | Incept, Llc | Medical organogel processes and compositions |
| US9594188B2 (en) | 2011-12-06 | 2017-03-14 | University Of Florida Research Foundation, Inc. | UV blocker loaded contact lenses |
| US9353313B2 (en) | 2012-08-09 | 2016-05-31 | Auburn University | Microdevices and methods of manufacture |
| CN104888669A (zh) * | 2014-03-05 | 2015-09-09 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种彩色水凝胶及其制备方法 |
| US10407527B2 (en) * | 2015-06-04 | 2019-09-10 | Mcmaster University | Charge-shifting polymers for tissue compatible hydrogels |
| KR102814241B1 (ko) | 2016-09-23 | 2025-05-29 | 인셉트, 엘엘씨 | 전안방내 약물 전달 데포 |
| JP7003987B2 (ja) * | 2017-03-24 | 2022-01-21 | 日本ゼオン株式会社 | 非水系二次電池用バインダー組成物及び非水系二次電池用スラリー組成物 |
| KR102114277B1 (ko) * | 2018-08-23 | 2020-05-22 | 주식회사 매스컨 | 고체 화장품 조성물 및 그 제조방법 |
| CN110559470B (zh) * | 2019-08-19 | 2021-02-09 | 浙江大学 | 一种水凝胶血管栓塞材料及形状记忆栓塞处理方法 |
| CN114073791B (zh) * | 2020-08-21 | 2022-05-31 | 中国科学院化学研究所 | 一种软骨组织工程支架及其制备方法与应用 |
| CN113121036A (zh) * | 2021-03-15 | 2021-07-16 | 太原理工大学 | 一种过硫酸盐降解抗生素废水的一体化装置 |
| JP2024545175A (ja) * | 2021-12-09 | 2024-12-05 | リカルダ、インコーポレイテッド | ヒドロゲルマイクロ粒子ベースの軟組織充填剤 |
| JP2024039880A (ja) * | 2022-09-12 | 2024-03-25 | 株式会社日本触媒 | ゲル粒子分散液の製造方法 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3822089A (en) * | 1968-09-25 | 1974-07-02 | Akademie Ved | Contact lens blank or replica made from anhydrous, sparingly cross-linked hydrophilic copolymers |
| CS153762B1 (enExample) | 1969-01-14 | 1974-03-29 | ||
| JPS492189B1 (enExample) * | 1970-10-28 | 1974-01-18 | ||
| CS163469B1 (enExample) * | 1972-05-22 | 1975-09-15 | ||
| US3948841A (en) * | 1972-05-22 | 1976-04-06 | Karel Dusek | Process for producing transparent gels with improved mechanical and sorption properties from copolymers of 2-hydroxyethyl methacrylate and amides of acrylic or methacrylic acid |
| US3963685A (en) * | 1974-05-13 | 1976-06-15 | Abrahams Robert A | Alcohol soluble hydrophilic polymer via aqueous polymerization |
| JPS5340038A (en) * | 1976-09-27 | 1978-04-12 | Japan Exlan Co Ltd | Preparation of microhydrogel |
| US4272518A (en) * | 1979-07-10 | 1981-06-09 | Moro Daniel G | Plastic wound bandage |
| EP0068684B1 (en) * | 1981-06-12 | 1986-08-13 | National Research Development Corporation | Preparation of particulate gels |
| JPS5911602B2 (ja) * | 1982-12-28 | 1984-03-16 | 東レ株式会社 | 診断用微粒子 |
| US4959217A (en) | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
| AU611244B2 (en) | 1987-12-25 | 1991-06-06 | Terumo Kabushiki Kaisha | Medical instrument |
| US5122544A (en) * | 1988-05-31 | 1992-06-16 | Nalco Chemical Company | Process for producing improved superabsorbent polymer aggregates from fines |
| US5840293A (en) * | 1988-11-16 | 1998-11-24 | Advanced Polymer Systems, Inc. | Ionic beads for controlled release and adsorption |
| US4962133A (en) * | 1989-09-05 | 1990-10-09 | Dow Corning Corporation | Method of making highly adsorptive copolymers |
| US5045266A (en) * | 1989-11-02 | 1991-09-03 | National Patent Development Corporation | Process of making a hearing aid earmold in situ |
| US5468811A (en) * | 1989-11-02 | 1995-11-21 | National Patent Development Corporation | Hydrophilic composite polymer articles formed from a settable paste comprising a mixture of hydrophilic polymer and unsaturated monomer |
| US5266325A (en) * | 1990-09-28 | 1993-11-30 | Hydro Med Science Division Of National Patent Development Corp. | Preparation of homogeneous hydrogel copolymers |
| AU651654B2 (en) * | 1992-01-14 | 1994-07-28 | Endo Pharmaceuticals Solutions Inc. | Manufacture of water-swellable hydrophilic articles and drug delivery devices |
| IT1243390B (it) * | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
| JP2993801B2 (ja) * | 1992-07-09 | 1999-12-27 | 株式会社日本触媒 | 粒子状含水ゲル状重合体および吸水性樹脂の製造方法 |
| DE69524214T3 (de) * | 1994-05-06 | 2008-05-15 | Pfizer Inc. | Azithromycin enthaltende arzneiverabreichungsformen mit gesteuerter wirkstoffabgabe |
| US5840338A (en) * | 1994-07-18 | 1998-11-24 | Roos; Eric J. | Loading of biologically active solutes into polymer gels |
| US5632774A (en) * | 1995-01-17 | 1997-05-27 | Babian; Hamik | In-the-shell hydration to make implant filler material and prosthesis employing same |
| JP3156955B2 (ja) * | 1995-07-12 | 2001-04-16 | 大日精化工業株式会社 | 連結されたミクロゲル粒子の製造方法及びそれで処理された物品 |
| AU676971B1 (en) * | 1995-08-24 | 1997-03-27 | Dainichiseika Color & Chemicals Mfg. Co. Ltd. | Production process of connected microgel particles and articles treated with connected microgel particles |
| DE19601764A1 (de) * | 1996-01-19 | 1997-07-24 | Hoechst Ag | Verfahren zur Herstellung hydrophiler, hochquellfähiger Hydrogele |
| JP2002505592A (ja) * | 1996-11-15 | 2002-02-19 | アドバンスト バイオ サーフェイシズ，インコーポレイティド | 生体内原位置で組織を修復するのに用いる生体用材料システム |
| WO1999015211A1 (en) * | 1997-09-19 | 1999-04-01 | Reprogenesis, Inc. | Improved hydrogel for tissue engineering |
| US5945457A (en) * | 1997-10-01 | 1999-08-31 | A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science | Process for preparing biologically compatible polymers and their use in medical devices |
| US6521431B1 (en) * | 1999-06-22 | 2003-02-18 | Access Pharmaceuticals, Inc. | Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments |
| JP2002284882A (ja) * | 2001-03-27 | 2002-10-03 | Mitsubishi Chemicals Corp | 高吸水性ポリマーの製造方法 |
| JP4883844B2 (ja) * | 2001-04-05 | 2012-02-22 | 住友精化株式会社 | カルボキシル基含有重合体粒子 |
| ES2385030T3 (es) * | 2001-06-29 | 2012-07-17 | Medgraft Microtech, Inc. | Implantes inyectables biodegradables y procedimientos relacionados con su fabricación y uso |
| WO2003022910A1 (en) * | 2001-09-08 | 2003-03-20 | Access Pharmaceuticals, Inc. | Synthesis and uses of polymer gel nanoparticle networks |
| JP2003261777A (ja) * | 2002-03-07 | 2003-09-19 | Japan Science & Technology Corp | 高圧により形成される分子複合体 |
| US7811605B2 (en) * | 2002-11-06 | 2010-10-12 | Uluru Inc. | Method of formation of shape-retentive aggregates of gel particles and their uses |
| US7351430B2 (en) * | 2002-11-06 | 2008-04-01 | Uluru Inc. | Shape-retentive hydrogel particle aggregates and their uses |
-
2002
- 2002-11-06 US US10/289,756 patent/US7351430B2/en not_active Expired - Fee Related
-
2003
- 2003-11-06 NZ NZ540571A patent/NZ540571A/en not_active IP Right Cessation
- 2003-11-06 EP EP03786614A patent/EP1567132A4/en not_active Withdrawn
- 2003-11-06 AU AU2003295428A patent/AU2003295428C1/en not_active Ceased
- 2003-11-06 CA CA 2512033 patent/CA2512033A1/en not_active Abandoned
- 2003-11-06 EP EP20060007351 patent/EP1674086A3/en not_active Ceased
- 2003-11-06 WO PCT/US2003/035671 patent/WO2004043438A1/en not_active Ceased
- 2003-11-06 JP JP2004551944A patent/JP2006514705A/ja not_active Ceased
-
2005
- 2005-06-06 ZA ZA200504624A patent/ZA200504624B/xx unknown
-
2007
- 2007-10-30 US US11/929,534 patent/US20080166409A1/en not_active Abandoned
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