JP2006514705A - 形状維持性ヒドロゲル粒子凝集体およびその使用法 - Google Patents

形状維持性ヒドロゲル粒子凝集体およびその使用法 Download PDF

Info

Publication number
JP2006514705A
JP2006514705A JP2004551944A JP2004551944A JP2006514705A JP 2006514705 A JP2006514705 A JP 2006514705A JP 2004551944 A JP2004551944 A JP 2004551944A JP 2004551944 A JP2004551944 A JP 2004551944A JP 2006514705 A JP2006514705 A JP 2006514705A
Authority
JP
Japan
Prior art keywords
shape
liquid
absorbed
retaining
aggregate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2004551944A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006514705A5 (enExample
Inventor
ジョン ジョン ブイ． セント
ダニエル ジー． モロ
ビル シー． ポンダー
Original Assignee
アクセス ファーマシューティカルズ， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アクセス ファーマシューティカルズ， インコーポレイテッド filed Critical アクセス ファーマシューティカルズ， インコーポレイテッド
Publication of JP2006514705A publication Critical patent/JP2006514705A/ja
Publication of JP2006514705A5 publication Critical patent/JP2006514705A5/ja
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/44—Radioisotopes, radionuclides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/04—Acids; Metal salts or ammonium salts thereof
    • C08F220/06—Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/102—Esters of polyhydric alcohols or polyhydric phenols of dialcohols, e.g. ethylene glycol di(meth)acrylate or 1,4-butanediol dimethacrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2312/00—Crosslinking
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2525—Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
JP2004551944A 2002-11-06 2003-11-06 形状維持性ヒドロゲル粒子凝集体およびその使用法 Ceased JP2006514705A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/289,756 US7351430B2 (en) 2002-11-06 2002-11-06 Shape-retentive hydrogel particle aggregates and their uses
PCT/US2003/035671 WO2004043438A1 (en) 2002-11-06 2003-11-06 Shape-retentive hydrogel particle aggregates and their uses

Publications (2)

Publication Number Publication Date
JP2006514705A true JP2006514705A (ja) 2006-05-11
JP2006514705A5 JP2006514705A5 (enExample) 2008-05-22

Family

ID=32176104

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004551944A Ceased JP2006514705A (ja) 2002-11-06 2003-11-06 形状維持性ヒドロゲル粒子凝集体およびその使用法

Country Status (8)

Country Link
US (2) US7351430B2 (enExample)
EP (2) EP1674086A3 (enExample)
JP (1) JP2006514705A (enExample)
AU (1) AU2003295428C1 (enExample)
CA (1) CA2512033A1 (enExample)
NZ (1) NZ540571A (enExample)
WO (1) WO2004043438A1 (enExample)
ZA (1) ZA200504624B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010506974A (ja) * 2006-10-13 2010-03-04 ウルル インコーポレイテッド インサイツで形成されるヒドロゲル創傷包帯および生体適合材料ならびにそれらの使用
JP2011529998A (ja) * 2008-08-06 2011-12-15 ウニベルシダーデ デ サンティアゴ デ コンポステラ 側鎖としてシクロデキストリンを有するアクリル系ハイドロゲル、その製造方法ならびに放出系およびコンタクトレンズ成分としてのその使用

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040083510A (ko) * 2002-02-15 2004-10-02 지엠에스, 엘엘씨 생체 의학 적용을 위한 중합 방법 및 재료
US7811605B2 (en) * 2002-11-06 2010-10-12 Uluru Inc. Method of formation of shape-retentive aggregates of gel particles and their uses
US7351430B2 (en) * 2002-11-06 2008-04-01 Uluru Inc. Shape-retentive hydrogel particle aggregates and their uses
US20050196343A1 (en) * 2004-02-27 2005-09-08 Molecular Therapeutics, Inc. Degradable nanoparticles
US8663225B2 (en) 2004-11-12 2014-03-04 Medtronic, Inc. Hydrogel bone void filler
US20060193894A1 (en) * 2005-02-28 2006-08-31 Jen James S Methods for providing biomedical devices with hydrophilic antimicrobial coatings
AU2006305989B2 (en) * 2005-10-26 2013-10-24 Genesis Technologies Limited Acellular bioabsorbable tissue regeneration matrices produced by incubating acellular blood products
EP1890147B1 (en) * 2005-11-01 2010-01-27 JSR Corporation Organic polymer particles and process for producing the same, magnetic particles for diagnostics, carboxyl group-containing particles and process for producing the same, and probe-bound particles and process for producing the same
US20080228268A1 (en) * 2007-03-15 2008-09-18 Uluru, Inc. Method of Formation of Viscous, Shape Conforming Gels and Their Uses as Medical Prosthesis
JP2011500898A (ja) * 2007-10-10 2011-01-06 ベンズ リサーチ アンド ディベロップメント コーポレーション 高い含水率および安定性を有するヒドロゲル
US20110009520A1 (en) * 2008-03-20 2011-01-13 Figuly Garret D Dimensionally stable, shaped articles comprised of dried, aggregated, water-swellable hydrogel microspheres and method of making same
EP2641567A1 (en) 2008-06-30 2013-09-25 Allergan, Inc. Fillable prosthetic implant with gel-like properties
JP2012235797A (ja) * 2009-09-18 2012-12-06 Terumo Corp ステント
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
CN107033368A (zh) 2009-11-09 2017-08-11 聚光灯技术合伙有限责任公司 碎裂水凝胶
US8927022B2 (en) 2009-11-25 2015-01-06 Healionics Corporation Granules of porous biocompatible materials
WO2011066441A1 (en) * 2009-11-25 2011-06-03 Healionics Corporation Implantable medical devices having microporous surface layers and method for reducing foreign body response to the same
EP3583960A1 (en) 2009-12-15 2019-12-25 Incept, LLC Implants and biodegradable fiducial markers
EP2555810B1 (en) * 2010-04-08 2018-08-22 Healionics Corporation Implantable medical devices having microporous surface layers and method for reducing foreign body response to the same
GB201110042D0 (en) * 2011-06-14 2011-07-27 Univ Edinburgh Growth of cells
US8883503B2 (en) * 2011-06-23 2014-11-11 Indian Institute Of Technology Kanpur Hydrogel scaffolds for tissue engineering
JP6199883B2 (ja) 2011-12-05 2017-09-20 インセプト・リミテッド・ライアビリティ・カンパニーＩｎｃｅｐｔ，Ｌｌｃ 医療用オルガノゲルプロセス及び組成物
US9594188B2 (en) * 2011-12-06 2017-03-14 University Of Florida Research Foundation, Inc. UV blocker loaded contact lenses
US9353313B2 (en) 2012-08-09 2016-05-31 Auburn University Microdevices and methods of manufacture
CN104888669A (zh) * 2014-03-05 2015-09-09 中国科学院苏州纳米技术与纳米仿生研究所 一种彩色水凝胶及其制备方法
US10407527B2 (en) * 2015-06-04 2019-09-10 Mcmaster University Charge-shifting polymers for tissue compatible hydrogels
KR20230053707A (ko) 2016-09-23 2023-04-21 인셉트, 엘엘씨 전안방내 약물 전달 데포
WO2018173717A1 (ja) * 2017-03-24 2018-09-27 日本ゼオン株式会社 非水系二次電池用バインダー組成物及び非水系二次電池用スラリー組成物
KR102114277B1 (ko) * 2018-08-23 2020-05-22 주식회사 매스컨 고체 화장품 조성물 및 그 제조방법
CN110559470B (zh) * 2019-08-19 2021-02-09 浙江大学 一种水凝胶血管栓塞材料及形状记忆栓塞处理方法
CN114073791B (zh) * 2020-08-21 2022-05-31 中国科学院化学研究所 一种软骨组织工程支架及其制备方法与应用
CN113121036A (zh) * 2021-03-15 2021-07-16 太原理工大学 一种过硫酸盐降解抗生素废水的一体化装置
EP4444369A4 (en) * 2021-12-09 2025-12-17 Likarda Inc SOFT FABRIC FILLERS BASED ON HYDROGEL MICROPARTICLES

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4950089A (enExample) * 1972-05-22 1974-05-15
JPS5340038A (en) * 1976-09-27 1978-04-12 Japan Exlan Co Ltd Preparation of microhydrogel
JPS585331A (ja) * 1981-06-12 1983-01-12 ブリティッシュ・テクノロジー・グループ・リミテッド 粒子状ゲルの製法
JPS58149910A (ja) * 1982-12-28 1983-09-06 Toray Ind Inc 診断用微粒子
JPH05247225A (ja) * 1992-07-09 1993-09-24 Nippon Shokubai Co Ltd 粒子状含水ゲル状重合体および吸水性樹脂の製造方法
JPH0925303A (ja) * 1995-07-12 1997-01-28 Dainichiseika Color & Chem Mfg Co Ltd 連結されたミクロゲル粒子の製造方法及びそれで処理された物品
JPH09208710A (ja) * 1996-01-19 1997-08-12 Hoechst Ag 親水性高膨潤性ヒドロゲルの製造方法
JP2001517494A (ja) * 1997-09-19 2001-10-09 リプロジェネシス・インコーポレーテッド 組織エンジニアリングのための改良されたヒドロゲル
JP2002284882A (ja) * 2001-03-27 2002-10-03 Mitsubishi Chemicals Corp 高吸水性ポリマーの製造方法
JP2002302616A (ja) * 2001-04-05 2002-10-18 Sumitomo Seika Chem Co Ltd カルボキシル基含有重合体粒子
JP2003261777A (ja) * 2002-03-07 2003-09-19 Japan Science & Technology Corp 高圧により形成される分子複合体

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3822089A (en) * 1968-09-25 1974-07-02 Akademie Ved Contact lens blank or replica made from anhydrous, sparingly cross-linked hydrophilic copolymers
CS153762B1 (enExample) 1969-01-14 1974-03-29
JPS492189B1 (enExample) * 1970-10-28 1974-01-18
US3948841A (en) * 1972-05-22 1976-04-06 Karel Dusek Process for producing transparent gels with improved mechanical and sorption properties from copolymers of 2-hydroxyethyl methacrylate and amides of acrylic or methacrylic acid
US3963685A (en) * 1974-05-13 1976-06-15 Abrahams Robert A Alcohol soluble hydrophilic polymer via aqueous polymerization
US4272518A (en) * 1979-07-10 1981-06-09 Moro Daniel G Plastic wound bandage
US4959217A (en) 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
AU611244B2 (en) 1987-12-25 1991-06-06 Terumo Kabushiki Kaisha Medical instrument
US5122544A (en) * 1988-05-31 1992-06-16 Nalco Chemical Company Process for producing improved superabsorbent polymer aggregates from fines
US5840293A (en) * 1988-11-16 1998-11-24 Advanced Polymer Systems, Inc. Ionic beads for controlled release and adsorption
US4962133A (en) * 1989-09-05 1990-10-09 Dow Corning Corporation Method of making highly adsorptive copolymers
US5045266A (en) * 1989-11-02 1991-09-03 National Patent Development Corporation Process of making a hearing aid earmold in situ
US5468811A (en) * 1989-11-02 1995-11-21 National Patent Development Corporation Hydrophilic composite polymer articles formed from a settable paste comprising a mixture of hydrophilic polymer and unsaturated monomer
AU651654B2 (en) * 1992-01-14 1994-07-28 Endo Pharmaceuticals Solutions Inc. Manufacture of water-swellable hydrophilic articles and drug delivery devices
US5266325A (en) * 1990-09-28 1993-11-30 Hydro Med Science Division Of National Patent Development Corp. Preparation of homogeneous hydrogel copolymers
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
AU680356B2 (en) * 1994-05-06 1997-07-24 Pfizer Inc. Controlled-release dosage forms of azithromycin
US5840338A (en) * 1994-07-18 1998-11-24 Roos; Eric J. Loading of biologically active solutes into polymer gels
US5632774A (en) * 1995-01-17 1997-05-27 Babian; Hamik In-the-shell hydration to make implant filler material and prosthesis employing same
AU676971B1 (en) * 1995-08-24 1997-03-27 Dainichiseika Color & Chemicals Mfg. Co. Ltd. Production process of connected microgel particles and articles treated with connected microgel particles
EP0873145A2 (en) * 1996-11-15 1998-10-28 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
US6521431B1 (en) * 1999-06-22 2003-02-18 Access Pharmaceuticals, Inc. Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments
KR100954741B1 (ko) * 2001-06-29 2010-04-27 메드 그래프트 마이크로텍 인코포레이션 생분해성 주사가능한 이식제 및 관련된 제조방법과 용도
US20030138490A1 (en) * 2001-09-08 2003-07-24 Zhibing Hu Synthesis and uses of polymer gel nanoparticle networks
US7811605B2 (en) * 2002-11-06 2010-10-12 Uluru Inc. Method of formation of shape-retentive aggregates of gel particles and their uses
US7351430B2 (en) * 2002-11-06 2008-04-01 Uluru Inc. Shape-retentive hydrogel particle aggregates and their uses

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4950089A (enExample) * 1972-05-22 1974-05-15
JPS5340038A (en) * 1976-09-27 1978-04-12 Japan Exlan Co Ltd Preparation of microhydrogel
JPS585331A (ja) * 1981-06-12 1983-01-12 ブリティッシュ・テクノロジー・グループ・リミテッド 粒子状ゲルの製法
JPS58149910A (ja) * 1982-12-28 1983-09-06 Toray Ind Inc 診断用微粒子
JPH05247225A (ja) * 1992-07-09 1993-09-24 Nippon Shokubai Co Ltd 粒子状含水ゲル状重合体および吸水性樹脂の製造方法
JPH0925303A (ja) * 1995-07-12 1997-01-28 Dainichiseika Color & Chem Mfg Co Ltd 連結されたミクロゲル粒子の製造方法及びそれで処理された物品
JPH09208710A (ja) * 1996-01-19 1997-08-12 Hoechst Ag 親水性高膨潤性ヒドロゲルの製造方法
JP2001517494A (ja) * 1997-09-19 2001-10-09 リプロジェネシス・インコーポレーテッド 組織エンジニアリングのための改良されたヒドロゲル
JP2002284882A (ja) * 2001-03-27 2002-10-03 Mitsubishi Chemicals Corp 高吸水性ポリマーの製造方法
JP2002302616A (ja) * 2001-04-05 2002-10-18 Sumitomo Seika Chem Co Ltd カルボキシル基含有重合体粒子
JP2003261777A (ja) * 2002-03-07 2003-09-19 Japan Science & Technology Corp 高圧により形成される分子複合体

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010506974A (ja) * 2006-10-13 2010-03-04 ウルル インコーポレイテッド インサイツで形成されるヒドロゲル創傷包帯および生体適合材料ならびにそれらの使用
JP2011529998A (ja) * 2008-08-06 2011-12-15 ウニベルシダーデ デ サンティアゴ デ コンポステラ 側鎖としてシクロデキストリンを有するアクリル系ハイドロゲル、その製造方法ならびに放出系およびコンタクトレンズ成分としてのその使用
US8951548B2 (en) 2008-08-06 2015-02-10 Universidade De Santiago De Compostela Acrylic hydrogels with pendant cyclodextrins, preparation method thereof and use of same as release systems and contact lens components

Also Published As

Publication number Publication date
AU2003295428A1 (en) 2004-06-03
AU2003295428B2 (en) 2009-02-12
US7351430B2 (en) 2008-04-01
EP1674086A2 (en) 2006-06-28
EP1567132A4 (en) 2007-03-21
WO2004043438A1 (en) 2004-05-27
US20040086548A1 (en) 2004-05-06
ZA200504624B (en) 2007-02-28
CA2512033A1 (en) 2004-05-27
US20080166409A1 (en) 2008-07-10
EP1674086A3 (en) 2007-03-21
AU2003295428C1 (en) 2009-07-30
EP1567132A1 (en) 2005-08-31
NZ540571A (en) 2008-05-30

Similar Documents

Publication Publication Date Title
JP2006514705A (ja) 形状維持性ヒドロゲル粒子凝集体およびその使用法
Khan et al. Synthesis, classification and properties of hydrogels: Their applications in drug delivery and agriculture
Jacob et al. Emerging role of hydrogels in drug delivery systems, tissue engineering and wound management
US20080063716A1 (en) Method of formation of shape-retentive aggregates of gel particles and their uses
KR101506621B1 (ko) 인시츄 형성된 하이드로겔 상처 드레싱 및 생체물질 그리고 그들의 사용
Abbas et al. Antitumor photodynamic therapy based on dipeptide fibrous hydrogels with incorporation of photosensitive drugs
Wu et al. Injectable and pH-responsive silk nanofiber hydrogels for sustained anticancer drug delivery
Ramanan et al. Development of a temperature‐sensitive composite hydrogel for drug delivery applications
TW200902097A (en) Method of formation of viscous, shape conforming gels and their uses as medical prosthesis
JP2010506974A5 (enExample)
Zulaikha et al. Nanoparticle-embedded hydrogels as a functional polymeric composite for biomedical applications
Khan et al. Biomedical applications of interpenetrating polymer network gels
Miao et al. Stimuli-responsive cellulose-based hydrogels
Abou El-Ela et al. Interpenetrating polymer network (IPN) nanoparticles for drug delivery applications
HK1093027A (en) Shape-retentive hydrogel particle aggregates and their uses
Weng et al. Hydrogels for Drug Delivery
Varaprasad et al. Nanostructured Polymer Blends: Chapter 8. Significances of Nanostructured Hydrogels for Valuable Applications
Censi et al. Hydrogels for Protein Delivery

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20061026

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20061026

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20080107

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20080107

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080328

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20090821

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090925

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091221

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101215

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110223

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20111109

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20111125

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20111201

A045 Written measure of dismissal of application [lapsed due to lack of payment]

Free format text: JAPANESE INTERMEDIATE CODE: A045

Effective date: 20120326