JP2006514636A5 - - Google Patents
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- Publication number
- JP2006514636A5 JP2006514636A5 JP2004557434A JP2004557434A JP2006514636A5 JP 2006514636 A5 JP2006514636 A5 JP 2006514636A5 JP 2004557434 A JP2004557434 A JP 2004557434A JP 2004557434 A JP2004557434 A JP 2004557434A JP 2006514636 A5 JP2006514636 A5 JP 2006514636A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- wta
- infection
- antibody
- staphylococcal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 20
- 239000012634 fragment Substances 0.000 claims 9
- 208000015181 infectious disease Diseases 0.000 claims 9
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 206010041925 Staphylococcal infections Diseases 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 5
- 208000034309 Bacterial disease carrier Diseases 0.000 claims 4
- 238000011109 contamination Methods 0.000 claims 3
- 230000009885 systemic effect Effects 0.000 claims 3
- 229960005486 vaccine Drugs 0.000 claims 3
- 241000295644 Staphylococcaceae Species 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 230000000941 anti-staphylcoccal effect Effects 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- VJDOAZKNBQCAGE-LMVFSUKVSA-N D-ribitol 5-phosphate Chemical compound OC[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O VJDOAZKNBQCAGE-LMVFSUKVSA-N 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 108090000988 Lysostaphin Proteins 0.000 claims 1
- 108010053775 Nisin Proteins 0.000 claims 1
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000004309 nisin Substances 0.000 claims 1
- 235000010297 nisin Nutrition 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43022502P | 2002-12-02 | 2002-12-02 | |
| PCT/US2003/038132 WO2004050846A2 (en) | 2002-12-02 | 2003-12-01 | Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514636A JP2006514636A (ja) | 2006-05-11 |
| JP2006514636A5 true JP2006514636A5 (cg-RX-API-DMAC7.html) | 2007-06-07 |
Family
ID=32469426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004557434A Pending JP2006514636A (ja) | 2002-12-02 | 2003-12-01 | 抗ブドウ球菌療法およびワクチンの標的としての壁テイコイン酸 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040247605A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1567868A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2006514636A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2003298770A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2507711A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004050846A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6824997B1 (en) | 1998-09-18 | 2004-11-30 | Binax, Inc. | Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies |
| US9134303B1 (en) | 1998-08-25 | 2015-09-15 | Alere Scarborough, Inc. | ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto |
| US8394379B2 (en) | 2003-05-15 | 2013-03-12 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| US8703134B2 (en) | 2003-05-15 | 2014-04-22 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| WO2007024852A2 (en) * | 2005-08-22 | 2007-03-01 | Biosynexus Incorporated | Methods for testing vaccine candidates against bacterial infection in rodents |
| AU2006303998A1 (en) * | 2005-10-11 | 2007-04-26 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Targeted biocides |
| AU2008292897B2 (en) * | 2007-08-31 | 2015-01-22 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
| US20110044968A1 (en) * | 2008-03-10 | 2011-02-24 | Pharmal N Corporation | Compositions for treatment with metallopeptidases, methods of making and using the same |
| US8598342B2 (en) | 2008-06-12 | 2013-12-03 | President And Fellows Of Harvard College | Methods and compounds for antimicrobial intervention |
| KR20110124060A (ko) * | 2010-05-10 | 2011-11-16 | 부산대학교 산학협력단 | Wta를 유효성분으로 함유하는 백신 조성물 |
| EP2780351B1 (en) | 2011-11-18 | 2019-12-18 | National Research Council of Canada (NRC) | Clostridium difficile lipoteichoic acid and uses thereof |
| CN103383354B (zh) * | 2012-05-03 | 2016-11-09 | 北京博迈世纪生物技术有限公司 | 一种检测肠毒素sea的磁微粒化学发光试剂盒的检测方法 |
| EP2848257A4 (en) * | 2012-05-07 | 2015-12-02 | Mogam Biotechnology Inst | VACCINE COMPOSITION FOR PREVENTING STAPHYLOCOCCUS AUREUS INFECTIONS |
| AR096388A1 (es) * | 2013-05-31 | 2015-12-30 | Genentech Inc | Anticuerpos anti-ácido teicoico de pared y sus conjugados |
| US9803002B2 (en) | 2013-05-31 | 2017-10-31 | Genentench, Inc. | Anti-wall teichoic antibodies and conjugates |
| BR112015029754A2 (pt) * | 2013-05-31 | 2017-09-26 | Genentech Inc | anticorpos anti-teicoico da parede e conjugados |
| EP3381939A1 (en) * | 2013-05-31 | 2018-10-03 | Genentech, Inc. | Anti-wall teichoic antibodies and conjugates |
| CN106413737A (zh) * | 2014-05-29 | 2017-02-15 | 株式会社绿十字 | 用于预防或治疗金黄色葡萄球菌感染的组合物 |
| BR112017011325A2 (pt) * | 2014-12-03 | 2020-07-21 | Genentech, Inc. | ?composto de conjugado anticorpo?antibiótico, composição, método de tratamento de uma infecção, método para matar staph aureus, processo para produzir o conjugado, kit para o tratamento de uma infecção, intermediários antibiótico-ligante e ligante-droga? |
| WO2017010845A1 (ko) * | 2015-07-15 | 2017-01-19 | 재단법인 목암생명과학연구소 | 포도상구균 감염 질환의 예방 또는 치료용 조성물 |
| JP2019519509A (ja) * | 2016-05-18 | 2019-07-11 | ゲンマブ ビー.ブイ. | 感染性疾患の治療における抗体およびその使用方法 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4250262A (en) * | 1979-12-14 | 1981-02-10 | Forsyth Dental Infirmary For Children | Method of preparing a purified glucosyltransferase |
| US5139933A (en) * | 1989-09-26 | 1992-08-18 | Vicam, L.P. | Assay method for detecting listeria |
| US5571511A (en) * | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
| US5290707A (en) * | 1991-11-25 | 1994-03-01 | The United States Of America As Represented By The Secretary Of The Army | Method for detection of microorganisms |
| US5367058A (en) * | 1993-08-25 | 1994-11-22 | Becton, Dickinson And Company | Modified antibodies with increased affinity |
| EP0732936B1 (de) * | 1993-12-09 | 2000-03-29 | Heinrich Exner | Adjuvans für antigene, verfahren zur herstellung und verwendung |
| US6350597B1 (en) * | 1994-01-13 | 2002-02-26 | E. I. Du Pont De Nemours & Company | Riboflavin synthase genes and enzymes and methods of use |
| US6203997B1 (en) * | 1994-06-08 | 2001-03-20 | Sepsis, Inc. | Quantitation of analytes in whole blood |
| ES2178699T3 (es) * | 1995-01-30 | 2003-01-01 | Lunamed Ag | Preparaciones antitumorales que contienen un acido lipoteicoico procedente de streptococcus. |
| EP0861321B1 (en) * | 1995-10-13 | 2006-05-31 | President And Fellows Of Harvard College | Phosphopantetheinyl transferases and uses thereof |
| US5770208A (en) * | 1996-09-11 | 1998-06-23 | Nabi | Staphylococcus aureus B-linked hexosamine antigen |
| US6610293B1 (en) * | 1997-06-16 | 2003-08-26 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria |
| US5889171A (en) * | 1997-07-18 | 1999-03-30 | Smithkline Beecham Corporation | TarF |
| ATE316794T1 (de) * | 1997-07-23 | 2006-02-15 | Ambi Inc | Pharmazeutische zusammensetzungen enthaltend lysostaphin allein oder in kombination mit einem antibiotikum zur behandlung von staphylokokkeninfektionen |
| US7250494B2 (en) * | 1998-06-15 | 2007-07-31 | Biosynexus Incorporated | Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria |
| US7252828B2 (en) * | 1998-07-15 | 2007-08-07 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
| US6703025B1 (en) * | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US6585973B1 (en) * | 1998-10-29 | 2003-07-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method for preparing solid phase conjugated vaccine |
| KR100790653B1 (ko) * | 1998-12-22 | 2007-12-31 | 마이크로싸이언스 리미티드 | 유전자와 단백질들, 및 그들의 사용 |
| US6569830B1 (en) * | 1999-03-05 | 2003-05-27 | Ambi, Inc. | Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains |
| CA2369762A1 (en) * | 1999-04-16 | 2000-10-26 | Peter P. Lee | A method for improving the half-life of soluble viral-specific ligands on mucosal membranes |
| US6974700B2 (en) * | 1999-06-14 | 2005-12-13 | Martin Levine | Kit for use in predicting refractory periodontal disease |
| WO2002045742A2 (en) * | 2000-09-12 | 2002-06-13 | U.S. Army Medical Research And Materiel Command | Lipoteichoic acid immunogenic compositions and methods of making and using thereof |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| US20030113350A1 (en) * | 2001-09-19 | 2003-06-19 | Fattom Ali I. | Glycoconjugate vaccines for use in immune-compromised populations |
| US6720160B2 (en) * | 2001-10-11 | 2004-04-13 | Helica Biosystems, Inc. | Method for simultaneous detection of multiple microbial antigens in biological specimens from mastitic animals |
| US7169903B2 (en) * | 2001-12-21 | 2007-01-30 | Biosynexus Incorporated | Multifunctional monoclonal antibodies directed to peptidoglycan of gram-positive bacteria |
| EP1474432A1 (en) * | 2002-02-04 | 2004-11-10 | Biomira Inc. | Immunostimulatory, covalently lipidated oligonucleotides |
| FR2842210B1 (fr) * | 2002-07-09 | 2012-12-14 | Mutabilis | Determinants de pathogenicite utilisables comme cibles pour l'elaboration de moyens de prevention et de controle d'infections bacteriennes et/ou de la dissemination systemique |
| US20040109853A1 (en) * | 2002-09-09 | 2004-06-10 | Reactive Surfaces, Ltd. | Biological active coating components, coatings, and coated surfaces |
| EP2392582A3 (en) * | 2003-04-25 | 2012-03-07 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore |
| US7422755B2 (en) * | 2004-01-15 | 2008-09-09 | The United States Of America As Represented By The Department Of Health And Human Services | Antimultiorganism glycoconjugate vaccine |
| KR100596443B1 (ko) * | 2004-04-27 | 2006-07-05 | 주식회사 하이닉스반도체 | 다수 뱅크 구조 디램을 위한 리프레시 제어회로 및 그 방법 |
| US20060134141A1 (en) * | 2004-12-14 | 2006-06-22 | Nabi Biopharmaceuticals | Glycoconjugate vaccines containing peptidoglycan |
| US20060228368A1 (en) * | 2005-04-07 | 2006-10-12 | Nabi Biopharmaceuticals | Method of protecting against staphylococcal infection |
| US20060269998A1 (en) * | 2005-04-15 | 2006-11-30 | North Carolina State University | Methods and compositions to modulate adhesion and stress tolerance in bacteria |
| US7521535B2 (en) * | 2006-09-20 | 2009-04-21 | The Board Of Regents For Oklahoma State University | Anti-microbial defensin-related peptides and methods of use |
-
2003
- 2003-12-01 WO PCT/US2003/038132 patent/WO2004050846A2/en not_active Ceased
- 2003-12-01 JP JP2004557434A patent/JP2006514636A/ja active Pending
- 2003-12-01 AU AU2003298770A patent/AU2003298770A1/en not_active Withdrawn
- 2003-12-01 US US10/724,194 patent/US20040247605A1/en not_active Abandoned
- 2003-12-01 EP EP03796528A patent/EP1567868A4/en not_active Withdrawn
- 2003-12-01 CA CA002507711A patent/CA2507711A1/en not_active Abandoned
-
2010
- 2010-01-29 AU AU2010200341A patent/AU2010200341A1/en not_active Abandoned