JP2006514636A - 抗ブドウ球菌療法およびワクチンの標的としての壁テイコイン酸 - Google Patents
抗ブドウ球菌療法およびワクチンの標的としての壁テイコイン酸 Download PDFInfo
- Publication number
- JP2006514636A JP2006514636A JP2004557434A JP2004557434A JP2006514636A JP 2006514636 A JP2006514636 A JP 2006514636A JP 2004557434 A JP2004557434 A JP 2004557434A JP 2004557434 A JP2004557434 A JP 2004557434A JP 2006514636 A JP2006514636 A JP 2006514636A
- Authority
- JP
- Japan
- Prior art keywords
- wta
- infection
- aureus
- antibody
- staphylococcal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24075—Lysostaphin (3.4.24.75)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43022502P | 2002-12-02 | 2002-12-02 | |
| PCT/US2003/038132 WO2004050846A2 (en) | 2002-12-02 | 2003-12-01 | Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514636A true JP2006514636A (ja) | 2006-05-11 |
| JP2006514636A5 JP2006514636A5 (https=) | 2007-06-07 |
Family
ID=32469426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004557434A Pending JP2006514636A (ja) | 2002-12-02 | 2003-12-01 | 抗ブドウ球菌療法およびワクチンの標的としての壁テイコイン酸 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040247605A1 (https=) |
| EP (1) | EP1567868A4 (https=) |
| JP (1) | JP2006514636A (https=) |
| AU (2) | AU2003298770A1 (https=) |
| CA (1) | CA2507711A1 (https=) |
| WO (1) | WO2004050846A2 (https=) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014237687A (ja) * | 2007-08-31 | 2014-12-18 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物 |
| JP2016525343A (ja) * | 2013-05-31 | 2016-08-25 | ジェネンテック, インコーポレイテッド | 抗細胞壁タイコ酸抗体及びコンジュゲート |
| JP2016532433A (ja) * | 2013-05-31 | 2016-10-20 | ジェネンテック, インコーポレイテッド | 抗細胞壁タイコ酸抗体及びコンジュゲート |
| JP2019519509A (ja) * | 2016-05-18 | 2019-07-11 | ゲンマブ ビー.ブイ. | 感染性疾患の治療における抗体およびその使用方法 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9134303B1 (en) | 1998-08-25 | 2015-09-15 | Alere Scarborough, Inc. | ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto |
| US6824997B1 (en) * | 1998-09-18 | 2004-11-30 | Binax, Inc. | Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies |
| US8394379B2 (en) | 2003-05-15 | 2013-03-12 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| US8703134B2 (en) | 2003-05-15 | 2014-04-22 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| WO2007024852A2 (en) * | 2005-08-22 | 2007-03-01 | Biosynexus Incorporated | Methods for testing vaccine candidates against bacterial infection in rodents |
| AU2006303998A1 (en) * | 2005-10-11 | 2007-04-26 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Targeted biocides |
| WO2009114520A2 (en) * | 2008-03-10 | 2009-09-17 | Pharmain Corporation | Compositions for treatment with metallopeptidases, methods of making and using the same |
| EP2303888B1 (en) * | 2008-06-12 | 2015-05-06 | President and Fellows of Harvard College | Compounds for antimicrobial intervention |
| KR20110124060A (ko) * | 2010-05-10 | 2011-11-16 | 부산대학교 산학협력단 | Wta를 유효성분으로 함유하는 백신 조성물 |
| US10364298B2 (en) | 2011-11-18 | 2019-07-30 | National Research Council Of Canada | Clostridium difficile lipoteichoic acid and uses thereof |
| CN103383354B (zh) * | 2012-05-03 | 2016-11-09 | 北京博迈世纪生物技术有限公司 | 一种检测肠毒素sea的磁微粒化学发光试剂盒的检测方法 |
| US20150147328A1 (en) * | 2012-05-07 | 2015-05-28 | Mogam Biotechnology Institute | Vaccine composition for preventing staphyllococcus aureus infection |
| AR096388A1 (es) * | 2013-05-31 | 2015-12-30 | Genentech Inc | Anticuerpos anti-ácido teicoico de pared y sus conjugados |
| US9803002B2 (en) | 2013-05-31 | 2017-10-31 | Genentench, Inc. | Anti-wall teichoic antibodies and conjugates |
| JP2017518373A (ja) * | 2014-05-29 | 2017-07-06 | グリーン・クロス・コーポレイションGreen Cross Corp. | スタフィロコッカス・アウレウス感染疾患の予防または治療用組成物 |
| HK1243931A1 (zh) * | 2014-12-03 | 2018-07-27 | F. Hoffmann-La Roche Ag | 抗金黄色葡萄球菌抗体利福霉素缀合物及其用途 |
| WO2017010845A1 (ko) * | 2015-07-15 | 2017-01-19 | 재단법인 목암생명과학연구소 | 포도상구균 감염 질환의 예방 또는 치료용 조성물 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4250262A (en) * | 1979-12-14 | 1981-02-10 | Forsyth Dental Infirmary For Children | Method of preparing a purified glucosyltransferase |
| US5139933A (en) * | 1989-09-26 | 1992-08-18 | Vicam, L.P. | Assay method for detecting listeria |
| US5571511A (en) * | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
| US5290707A (en) * | 1991-11-25 | 1994-03-01 | The United States Of America As Represented By The Secretary Of The Army | Method for detection of microorganisms |
| US5367058A (en) * | 1993-08-25 | 1994-11-22 | Becton, Dickinson And Company | Modified antibodies with increased affinity |
| AU1218295A (en) * | 1993-12-09 | 1995-06-27 | Heinrich Exner | Adjuvant for antigens, process for producing the same and its use |
| US6350597B1 (en) * | 1994-01-13 | 2002-02-26 | E. I. Du Pont De Nemours & Company | Riboflavin synthase genes and enzymes and methods of use |
| US6203997B1 (en) * | 1994-06-08 | 2001-03-20 | Sepsis, Inc. | Quantitation of analytes in whole blood |
| CN1113102C (zh) * | 1995-01-30 | 2003-07-02 | 彼得·特鲁格 | 抗肿瘤制剂 |
| AU727348B2 (en) * | 1995-10-13 | 2000-12-14 | President And Fellows Of Harvard College | Phosphopantetheinyl transferases and uses thereof |
| US5770208A (en) * | 1996-09-11 | 1998-06-23 | Nabi | Staphylococcus aureus B-linked hexosamine antigen |
| US6610293B1 (en) * | 1997-06-16 | 2003-08-26 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria |
| US5889171A (en) * | 1997-07-18 | 1999-03-30 | Smithkline Beecham Corporation | TarF |
| IL134056A0 (en) * | 1997-07-23 | 2001-04-30 | Ambi Inc | Pharmaceutical compositions containing lysostaphin alone or in combination with an antibiotic for the treatment of staphylococcal infections |
| US7250494B2 (en) * | 1998-06-15 | 2007-07-31 | Biosynexus Incorporated | Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria |
| US7252828B2 (en) * | 1998-07-15 | 2007-08-07 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
| US6703025B1 (en) * | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US6585973B1 (en) * | 1998-10-29 | 2003-07-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method for preparing solid phase conjugated vaccine |
| PT1141308E (pt) * | 1998-12-22 | 2007-05-31 | Microscience Ltd | Ptroteínas de streptococcus do grupo b e sua utilização |
| US6569830B1 (en) * | 1999-03-05 | 2003-05-27 | Ambi, Inc. | Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains |
| US6365156B1 (en) * | 1999-04-16 | 2002-04-02 | Osel, Inc. | Method for improving the half-life of soluble viral-specific ligands on mucosal membranes |
| US6974700B2 (en) * | 1999-06-14 | 2005-12-13 | Martin Levine | Kit for use in predicting refractory periodontal disease |
| WO2002045742A2 (en) * | 2000-09-12 | 2002-06-13 | U.S. Army Medical Research And Materiel Command | Lipoteichoic acid immunogenic compositions and methods of making and using thereof |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| US20030113350A1 (en) * | 2001-09-19 | 2003-06-19 | Fattom Ali I. | Glycoconjugate vaccines for use in immune-compromised populations |
| US6720160B2 (en) * | 2001-10-11 | 2004-04-13 | Helica Biosystems, Inc. | Method for simultaneous detection of multiple microbial antigens in biological specimens from mastitic animals |
| US7169903B2 (en) * | 2001-12-21 | 2007-01-30 | Biosynexus Incorporated | Multifunctional monoclonal antibodies directed to peptidoglycan of gram-positive bacteria |
| EP1474432A1 (en) * | 2002-02-04 | 2004-11-10 | Biomira Inc. | Immunostimulatory, covalently lipidated oligonucleotides |
| FR2842210B1 (fr) * | 2002-07-09 | 2012-12-14 | Mutabilis | Determinants de pathogenicite utilisables comme cibles pour l'elaboration de moyens de prevention et de controle d'infections bacteriennes et/ou de la dissemination systemique |
| US20040109853A1 (en) * | 2002-09-09 | 2004-06-10 | Reactive Surfaces, Ltd. | Biological active coating components, coatings, and coated surfaces |
| AU2004235346A1 (en) * | 2003-04-25 | 2004-11-11 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore |
| US7422755B2 (en) * | 2004-01-15 | 2008-09-09 | The United States Of America As Represented By The Department Of Health And Human Services | Antimultiorganism glycoconjugate vaccine |
| KR100596443B1 (ko) * | 2004-04-27 | 2006-07-05 | 주식회사 하이닉스반도체 | 다수 뱅크 구조 디램을 위한 리프레시 제어회로 및 그 방법 |
| US20060134141A1 (en) * | 2004-12-14 | 2006-06-22 | Nabi Biopharmaceuticals | Glycoconjugate vaccines containing peptidoglycan |
| US20060228368A1 (en) * | 2005-04-07 | 2006-10-12 | Nabi Biopharmaceuticals | Method of protecting against staphylococcal infection |
| AU2006236629B2 (en) * | 2005-04-15 | 2012-04-19 | North Carolina State University | Methods and compositions to modulate adhesion and stress tolerance in bacteria |
| US7521535B2 (en) * | 2006-09-20 | 2009-04-21 | The Board Of Regents For Oklahoma State University | Anti-microbial defensin-related peptides and methods of use |
-
2003
- 2003-12-01 EP EP03796528A patent/EP1567868A4/en not_active Withdrawn
- 2003-12-01 WO PCT/US2003/038132 patent/WO2004050846A2/en not_active Ceased
- 2003-12-01 CA CA002507711A patent/CA2507711A1/en not_active Abandoned
- 2003-12-01 US US10/724,194 patent/US20040247605A1/en not_active Abandoned
- 2003-12-01 JP JP2004557434A patent/JP2006514636A/ja active Pending
- 2003-12-01 AU AU2003298770A patent/AU2003298770A1/en not_active Abandoned
-
2010
- 2010-01-29 AU AU2010200341A patent/AU2010200341A1/en not_active Abandoned
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014237687A (ja) * | 2007-08-31 | 2014-12-18 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物 |
| JP2017002080A (ja) * | 2007-08-31 | 2017-01-05 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物 |
| JP2016525343A (ja) * | 2013-05-31 | 2016-08-25 | ジェネンテック, インコーポレイテッド | 抗細胞壁タイコ酸抗体及びコンジュゲート |
| JP2016532433A (ja) * | 2013-05-31 | 2016-10-20 | ジェネンテック, インコーポレイテッド | 抗細胞壁タイコ酸抗体及びコンジュゲート |
| JP2019519509A (ja) * | 2016-05-18 | 2019-07-11 | ゲンマブ ビー.ブイ. | 感染性疾患の治療における抗体およびその使用方法 |
| JP2022105143A (ja) * | 2016-05-18 | 2022-07-12 | ゲンマブ ビー.ブイ. | 感染性疾患の治療における抗体およびその使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003298770A2 (en) | 2004-06-23 |
| WO2004050846A2 (en) | 2004-06-17 |
| AU2010200341A1 (en) | 2010-02-18 |
| EP1567868A2 (en) | 2005-08-31 |
| AU2003298770A1 (en) | 2004-06-23 |
| WO2004050846A8 (en) | 2004-09-16 |
| WO2004050846A3 (en) | 2005-03-17 |
| CA2507711A1 (en) | 2004-06-17 |
| US20040247605A1 (en) | 2004-12-09 |
| EP1567868A4 (en) | 2008-02-06 |
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