JP2006514035A - 心不整脈の予防および治療 - Google Patents

心不整脈の予防および治療 Download PDF

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Publication number
JP2006514035A
JP2006514035A JP2004562291A JP2004562291A JP2006514035A JP 2006514035 A JP2006514035 A JP 2006514035A JP 2004562291 A JP2004562291 A JP 2004562291A JP 2004562291 A JP2004562291 A JP 2004562291A JP 2006514035 A JP2006514035 A JP 2006514035A
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Japan
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ala
gly
ser
glp
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JP2004562291A
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English (en)
Japanese (ja)
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JP2006514035A5 (enExample
Inventor
デイビッド・アール・ハサウェイ
アラン・ディ・バロン
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Amylin Pharmaceuticals LLC
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Amylin Pharmaceuticals LLC
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Application filed by Amylin Pharmaceuticals LLC filed Critical Amylin Pharmaceuticals LLC
Publication of JP2006514035A publication Critical patent/JP2006514035A/ja
Publication of JP2006514035A5 publication Critical patent/JP2006514035A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2278Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2004562291A 2002-12-17 2003-12-17 心不整脈の予防および治療 Pending JP2006514035A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43450802P 2002-12-17 2002-12-17
US43488802P 2002-12-19 2002-12-19
PCT/US2003/040504 WO2004056313A2 (en) 2002-12-17 2003-12-17 Prevention and treatment of cardiac arrhythmias

Publications (2)

Publication Number Publication Date
JP2006514035A true JP2006514035A (ja) 2006-04-27
JP2006514035A5 JP2006514035A5 (enExample) 2006-11-30

Family

ID=32685317

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004562291A Pending JP2006514035A (ja) 2002-12-17 2003-12-17 心不整脈の予防および治療

Country Status (4)

Country Link
EP (1) EP1610811A4 (enExample)
JP (1) JP2006514035A (enExample)
AU (1) AU2003297356A1 (enExample)
WO (1) WO2004056313A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009538356A (ja) * 2006-05-26 2009-11-05 アミリン・ファーマシューティカルズ,インコーポレイテッド 鬱血性心不全の治療のための組成物および方法
JP2010533709A (ja) * 2007-07-16 2010-10-28 ハンミ ファーマシューティカル カンパニー リミテッド N末端のアミノ酸が変性したインスリン分泌ペプチド誘導体
JP2014530892A (ja) * 2011-10-28 2014-11-20 ファリス バイオテック ゲーエムベーハー 心臓虚血再灌流障害からの保護のためのポリペプチド
JP2022549730A (ja) * 2019-09-25 2022-11-28 成都奥▲達▼生物科技有限公司 エキセナチド類似体
JP2024056786A (ja) * 2020-01-30 2024-04-23 イーライ リリー アンド カンパニー チルゼパチドの治療的使用

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8603969B2 (en) 2004-02-11 2013-12-10 Amylin Pharmaceuticals, Llc Pancreatic polypeptide family motifs and polypeptides comprising the same
US8076288B2 (en) 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
WO2006086769A2 (en) 2005-02-11 2006-08-17 Amylin Pharmaceuticals, Inc. Gip analog and hybrid polypeptides with selectable properties
US8263545B2 (en) 2005-02-11 2012-09-11 Amylin Pharmaceuticals, Inc. GIP analog and hybrid polypeptides with selectable properties
WO2006110887A2 (en) * 2005-04-11 2006-10-19 Amylin Pharmaceuticals, Inc Use of glp-1, exendin and agonists thereof to delay or prevent cardiac remodeling
EP2330124B1 (en) * 2005-08-11 2015-02-25 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
JP2009504681A (ja) * 2005-08-11 2009-02-05 アミリン・ファーマシューティカルズ,インコーポレイテッド 選択可能な特性を有するハイブリッドポリペプチド
US8497240B2 (en) 2006-08-17 2013-07-30 Amylin Pharmaceuticals, Llc DPP-IV resistant GIP hybrid polypeptides with selectable properties
RU2413528C2 (ru) 2007-01-18 2011-03-10 Открытое Акционерное Общество "Валента Фармацевтика" Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения
WO2009040068A2 (en) * 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
SMT201700189T1 (it) 2008-12-10 2017-05-08 Glaxosmithkline Llc Composizioni farmaceutiche di albiglutide
WO2011140176A1 (en) 2010-05-04 2011-11-10 Glaxosmithkline Llc Methods for treating or preventing cardiovascular disorders and providing cardiovascular protection
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
PT2934568T (pt) 2012-12-21 2018-01-04 Sanofi Sa Agonistas duplos de glp1/gip ou trigonais de glp1/gip/glucagina
TW201609795A (zh) 2013-12-13 2016-03-16 賽諾菲公司 作為雙重glp-1/gip受體促效劑的艾塞那肽-4(exendin-4)胜肽類似物
TW201609797A (zh) 2013-12-13 2016-03-16 賽諾菲公司 雙重glp-1/升糖素受體促效劑
TW201609799A (zh) 2013-12-13 2016-03-16 賽諾菲公司 雙重glp-1/gip受體促效劑
TW201609796A (zh) 2013-12-13 2016-03-16 賽諾菲公司 非醯化之艾塞那肽-4(exendin-4)胜肽類似物
TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自exendin-4之雙重glp-1/升糖素受體促效劑
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
RU2573933C1 (ru) 2014-08-21 2016-01-27 Дафот Энтерпрайсис Лимитед Пептид для лечения сахарного диабета 2-го типа и его осложнений
AR105319A1 (es) 2015-06-05 2017-09-27 Sanofi Sa Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
TW201706291A (zh) 2015-07-10 2017-02-16 賽諾菲公司 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物
EP3474820B1 (en) 2017-08-24 2024-02-07 Novo Nordisk A/S Glp-1 compositions and uses thereof
CN108939052B (zh) * 2018-09-04 2021-03-16 江苏省中医药研究院 艾塞那肽在制备预防或治疗房颤的药物中的用途
PE20230819A1 (es) 2020-02-18 2023-05-19 Novo Nordisk As Composiciones y usos de glp-1

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000066138A2 (en) * 1999-04-30 2000-11-09 Bionebraska, Inc. Metabolic intervention with glp-1 to improve the function of ischemic and reperfused tissue
US20020107206A1 (en) * 2000-05-19 2002-08-08 Coolidge Thomas R. Treatment of acute coronary syndrome with GLP-1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277819B1 (en) * 1996-08-30 2001-08-21 Eli Lilly And Company Use of GLP-1 or analogs in treatment of myocardial infarction
CA2320371C (en) * 1998-02-13 2012-01-17 Amylin Pharmaceuticals, Inc. Inotropic and diuretic effects of exendin and glp-1
US20020061838A1 (en) * 2000-05-17 2002-05-23 Barton Holmquist Peptide pharmaceutical formulations
NZ519752A (en) * 2000-10-20 2005-04-29 Amylin Pharmaceuticals Inc Treatment of hibernating myocardium and diabetic cardiomyopathy with a GLP-1 peptide
WO2002085406A1 (en) * 2001-04-24 2002-10-31 Restoragen, Inc. Methods and compositions for treating conditions associated with insulin resistance

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000066138A2 (en) * 1999-04-30 2000-11-09 Bionebraska, Inc. Metabolic intervention with glp-1 to improve the function of ischemic and reperfused tissue
US20020107206A1 (en) * 2000-05-19 2002-08-08 Coolidge Thomas R. Treatment of acute coronary syndrome with GLP-1

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009538356A (ja) * 2006-05-26 2009-11-05 アミリン・ファーマシューティカルズ,インコーポレイテッド 鬱血性心不全の治療のための組成物および方法
JP2010533709A (ja) * 2007-07-16 2010-10-28 ハンミ ファーマシューティカル カンパニー リミテッド N末端のアミノ酸が変性したインスリン分泌ペプチド誘導体
JP2013014598A (ja) * 2007-07-16 2013-01-24 Hanmi Science Co Ltd N末端のアミノ酸が変性したインスリン分泌ペプチド誘導体
JP2014094948A (ja) * 2007-07-16 2014-05-22 Hanmi Science Co Ltd N末端のアミノ酸が変性したインスリン分泌ペプチド誘導体
JP2015166368A (ja) * 2007-07-16 2015-09-24 ハンミ サイエンス カンパニー リミテッドHanmi Scienceco.,Ltd. N末端のアミノ酸が変性したエキセンディン−4誘導体
JP2015172058A (ja) * 2007-07-16 2015-10-01 ハンミ サイエンス カンパニー リミテッドHanmi Scienceco.,Ltd. N末端のアミノ酸が変性したエキセンディン−4誘導体
JP2014530892A (ja) * 2011-10-28 2014-11-20 ファリス バイオテック ゲーエムベーハー 心臓虚血再灌流障害からの保護のためのポリペプチド
JP2022549730A (ja) * 2019-09-25 2022-11-28 成都奥▲達▼生物科技有限公司 エキセナチド類似体
JP7491610B2 (ja) 2019-09-25 2024-05-28 成都奥▲達▼生物科技有限公司 エキセナチド類似体
JP2024056786A (ja) * 2020-01-30 2024-04-23 イーライ リリー アンド カンパニー チルゼパチドの治療的使用

Also Published As

Publication number Publication date
EP1610811A4 (en) 2008-03-26
WO2004056313A3 (en) 2004-11-25
AU2003297356A1 (en) 2004-07-14
AU2003297356A8 (en) 2004-07-14
WO2004056313A2 (en) 2004-07-08
EP1610811A2 (en) 2006-01-04

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