WO2004056313A3 - Prevention and treatment of cardiac arrhythmias - Google Patents
Prevention and treatment of cardiac arrhythmias Download PDFInfo
- Publication number
- WO2004056313A3 WO2004056313A3 PCT/US2003/040504 US0340504W WO2004056313A3 WO 2004056313 A3 WO2004056313 A3 WO 2004056313A3 US 0340504 W US0340504 W US 0340504W WO 2004056313 A3 WO2004056313 A3 WO 2004056313A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- treatment
- prevention
- cardiac arrhythmias
- glucagon
- peptide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003297356A AU2003297356A1 (en) | 2002-12-17 | 2003-12-17 | Prevention and treatment of cardiac arrhythmias |
JP2004562291A JP2006514035A (en) | 2002-12-17 | 2003-12-17 | Prevention and treatment of cardiac arrhythmias |
EP03813770A EP1610811A4 (en) | 2002-12-17 | 2003-12-17 | Prevention and treatment of cardiac arrhythmias |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43450802P | 2002-12-17 | 2002-12-17 | |
US60/434,508 | 2002-12-17 | ||
US43488802P | 2002-12-19 | 2002-12-19 | |
US60/434,888 | 2002-12-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004056313A2 WO2004056313A2 (en) | 2004-07-08 |
WO2004056313A3 true WO2004056313A3 (en) | 2004-11-25 |
Family
ID=32685317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/040504 WO2004056313A2 (en) | 2002-12-17 | 2003-12-17 | Prevention and treatment of cardiac arrhythmias |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1610811A4 (en) |
JP (1) | JP2006514035A (en) |
AU (1) | AU2003297356A1 (en) |
WO (1) | WO2004056313A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108939052A (en) * | 2018-09-04 | 2018-12-07 | 江苏省中医药研究院 | Purposes of the Exenatide in the drug of preparation prevention or treatment atrial fibrillation |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
AU2005211776B2 (en) | 2004-02-11 | 2012-02-02 | Amylin Pharmaceuticals, Llc | Pancreatic polypeptide family motifs and polypeptides comprising the same |
US8263545B2 (en) | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
AU2006213607A1 (en) | 2005-02-11 | 2006-08-17 | Amylin Pharmaceuticals, Llc | GIP analog and hybrid polypeptides with selectable properties |
US8946149B2 (en) | 2005-04-11 | 2015-02-03 | Amylin Pharmaceuticals, Llc | Use of exendin and analogs thereof to delay or prevent cardiac remodeling |
AU2006279680B2 (en) * | 2005-08-11 | 2012-12-06 | Amylin Pharmaceuticals, Llc | Hybrid polypeptides with selectable properties |
KR101399178B1 (en) * | 2005-08-11 | 2014-06-18 | 아스트라제네카 파마수티컬스 엘피 | Hybrid polypeptides with selectable properties |
WO2007139941A2 (en) * | 2006-05-26 | 2007-12-06 | Amylin Pharmaceuticals, Inc. | Composition and methods for treatment of congestive heart failure |
US8497240B2 (en) | 2006-08-17 | 2013-07-30 | Amylin Pharmaceuticals, Llc | DPP-IV resistant GIP hybrid polypeptides with selectable properties |
RU2413528C2 (en) | 2007-01-18 | 2011-03-10 | Открытое Акционерное Общество "Валента Фармацевтика" | Exenatide and dalargin drug for treating diabetes, adminisration and therapy |
JP2009019027A (en) * | 2007-07-16 | 2009-01-29 | Hanmi Pharmaceutical Co Ltd | Insulin secretion peptide derivative in which amino acid of amino terminal is varied |
RU2010113997A (en) * | 2007-09-11 | 2011-10-20 | Мондобайотек Лабораториз Аг (Li) | THYROLIBERIN FOR THERAPEUTIC USE |
HUE031900T2 (en) | 2008-12-10 | 2017-08-28 | Glaxosmithkline Llc | Pharmaceutical compositions of albiglutide |
EP2566502A4 (en) | 2010-05-04 | 2013-10-09 | Glaxosmithkline Llc | Methods for treating or preventing cardiovascular disorders and providing cardiovascular protection |
EP2771025A1 (en) * | 2011-10-28 | 2014-09-03 | Pharis Biotec GmbH | A polypeptide for the protection against heart ischemia-reperfusion injury |
UA116217C2 (en) | 2012-10-09 | 2018-02-26 | Санофі | Exendin-4 derivatives as dual glp1/glucagon agonists |
JP2016503771A (en) | 2012-12-21 | 2016-02-08 | サノフイ | Exendin-4 derivative |
WO2015086729A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/gip receptor agonists |
TW201609796A (en) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | Non-acylated EXENDIN-4 peptide analogues |
EP3080149A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Dual glp-1/glucagon receptor agonists |
EP3080150B1 (en) | 2013-12-13 | 2018-08-01 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
TW201625669A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Peptidic dual GLP-1/glucagon receptor agonists derived from Exendin-4 |
TW201625668A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Exendin-4 derivatives as peptidic dual GLP-1/glucagon receptor agonists |
TW201625670A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Dual GLP-1/glucagon receptor agonists derived from EXENDIN-4 |
US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
RU2573933C1 (en) | 2014-08-21 | 2016-01-27 | Дафот Энтерпрайсис Лимитед | Peptide for medical treatment of pancreatic diabetes of 2nd type and its complications |
AR105319A1 (en) | 2015-06-05 | 2017-09-27 | Sanofi Sa | PROPHARMS THAT INCLUDE A DUAL AGONIST GLU-1 / GLUCAGON CONJUGATE HIALURONIC ACID CONNECTOR |
AR105284A1 (en) | 2015-07-10 | 2017-09-20 | Sanofi Sa | DERIVATIVES OF EXENDINA-4 AS SPECIFIC DUAL PEPTIDE AGONISTS OF GLP-1 / GLUCAGÓN RECEPTORS |
CN111050750A (en) | 2017-08-24 | 2020-04-21 | 诺沃挪第克公司 | GLP-1 compositions and uses thereof |
CN110551203B (en) * | 2019-09-25 | 2023-02-10 | 成都奥达生物科技有限公司 | Exenatide analogue |
MX2022009523A (en) | 2020-02-18 | 2022-09-09 | Novo Nordisk As | Pharmaceutical formulations. |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6284725B1 (en) * | 1998-10-08 | 2001-09-04 | Bionebraska, Inc. | Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue |
US20020107206A1 (en) * | 2000-05-19 | 2002-08-08 | Coolidge Thomas R. | Treatment of acute coronary syndrome with GLP-1 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6277819B1 (en) * | 1996-08-30 | 2001-08-21 | Eli Lilly And Company | Use of GLP-1 or analogs in treatment of myocardial infarction |
AU759058C (en) * | 1998-02-13 | 2005-09-15 | Amylin Pharmaceuticals, Inc. | Inotropic and diuretic effects of exendin and GLP-1 |
US20020061838A1 (en) * | 2000-05-17 | 2002-05-23 | Barton Holmquist | Peptide pharmaceutical formulations |
DE60142351D1 (en) * | 2000-10-20 | 2010-07-22 | Amylin Pharmaceuticals Inc | TREATMENT OF HYPOACTIVE MYOKARD AND DIABETIC HEART MYOPATHY WITH A GLP-1 PEPTIDE |
WO2002085406A1 (en) * | 2001-04-24 | 2002-10-31 | Restoragen, Inc. | Methods and compositions for treating conditions associated with insulin resistance |
-
2003
- 2003-12-17 JP JP2004562291A patent/JP2006514035A/en active Pending
- 2003-12-17 AU AU2003297356A patent/AU2003297356A1/en not_active Abandoned
- 2003-12-17 WO PCT/US2003/040504 patent/WO2004056313A2/en active Application Filing
- 2003-12-17 EP EP03813770A patent/EP1610811A4/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6284725B1 (en) * | 1998-10-08 | 2001-09-04 | Bionebraska, Inc. | Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue |
US20020107206A1 (en) * | 2000-05-19 | 2002-08-08 | Coolidge Thomas R. | Treatment of acute coronary syndrome with GLP-1 |
Non-Patent Citations (2)
Title |
---|
NIKOLAIDIS ET AL.: "GLP-1 improves myocardial performance in conscious dogs with pacing induced heart failure", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 37, no. 2, February 2001 (2001-02-01), pages 218A, XP001053523 * |
See also references of EP1610811A4 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108939052A (en) * | 2018-09-04 | 2018-12-07 | 江苏省中医药研究院 | Purposes of the Exenatide in the drug of preparation prevention or treatment atrial fibrillation |
CN108939052B (en) * | 2018-09-04 | 2021-03-16 | 江苏省中医药研究院 | Application of exenatide in preparation of medicine for preventing or treating atrial fibrillation |
Also Published As
Publication number | Publication date |
---|---|
EP1610811A4 (en) | 2008-03-26 |
AU2003297356A8 (en) | 2004-07-14 |
EP1610811A2 (en) | 2006-01-04 |
AU2003297356A1 (en) | 2004-07-14 |
JP2006514035A (en) | 2006-04-27 |
WO2004056313A2 (en) | 2004-07-08 |
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