JP2006513149A5 - - Google Patents
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- Publication number
- JP2006513149A5 JP2006513149A5 JP2004538165A JP2004538165A JP2006513149A5 JP 2006513149 A5 JP2006513149 A5 JP 2006513149A5 JP 2004538165 A JP2004538165 A JP 2004538165A JP 2004538165 A JP2004538165 A JP 2004538165A JP 2006513149 A5 JP2006513149 A5 JP 2006513149A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- composition
- isolated polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 238000006467 substitution reaction Methods 0.000 claims 5
- 101000925662 Enterobacteria phage PRD1 Endolysin Proteins 0.000 claims 3
- 108010043121 Green Fluorescent Proteins Proteins 0.000 claims 2
- 102000004144 Green Fluorescent Proteins Human genes 0.000 claims 2
- 239000005090 green fluorescent protein Substances 0.000 claims 2
- 241000193738 Bacillus anthracis Species 0.000 claims 1
- 241001660259 Cereus <cactus> Species 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 101700012268 Holin Proteins 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 229940065181 bacillus anthracis Drugs 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000006641 stabilisation Effects 0.000 claims 1
- 238000011105 stabilization Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38087502P | 2002-05-17 | 2002-05-17 | |
| PCT/US2003/015719 WO2004027020A2 (en) | 2002-05-17 | 2003-05-19 | Identification of a phage associated lytic enzyme to rapidly and specifically detect and kill bacillus anthracis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006513149A JP2006513149A (ja) | 2006-04-20 |
| JP2006513149A5 true JP2006513149A5 (https=) | 2008-02-14 |
Family
ID=32030583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004538165A Pending JP2006513149A (ja) | 2002-05-17 | 2003-05-19 | Ｂａｃｉｌｌｕｓａｎｔｈｒａｃｉｓを迅速かつ特異的に検出および殺滅するファージ関連溶菌酵素の同定 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7402309B2 (https=) |
| EP (1) | EP1501925A4 (https=) |
| JP (1) | JP2006513149A (https=) |
| AU (1) | AU2003291614A1 (https=) |
| CA (1) | CA2486280A1 (https=) |
| WO (1) | WO2004027020A2 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7527966B2 (en) * | 2002-06-26 | 2009-05-05 | Transgenrx, Inc. | Gene regulation in transgenic animals using a transposon-based vector |
| US20040172667A1 (en) * | 2002-06-26 | 2004-09-02 | Cooper Richard K. | Administration of transposon-based vectors to reproductive organs |
| WO2005062881A2 (en) | 2003-12-24 | 2005-07-14 | Transgenrx, Inc. | Gene therapy using transposon-based vectors |
| RU2296576C2 (ru) * | 2005-05-18 | 2007-04-10 | Институт биохимии и физиологии микроорганизмов им. Г.К. Скрябина РАН | СРЕДСТВО, ОБЛАДАЮЩЕЕ БАКТЕРИЦИДНЫМ ДЕЙСТВИЕМ В ОТНОШЕНИИ ВЕГЕТАТИВНЫХ И СПОРОВЫХ КЛЕТОК Bacillus anthracis, СПОСОБ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ СИБИРСКОЙ ЯЗВЫ |
| US8389469B2 (en) * | 2005-06-06 | 2013-03-05 | The Rockefeller University | Bacteriophage lysins for Bacillus anthracis |
| EP2360248A1 (en) * | 2005-08-24 | 2011-08-24 | The Rockefeller University | Ply-GBS mutant lysins |
| CN100395341C (zh) * | 2006-03-09 | 2008-06-18 | 中国人民解放军军事医学科学院生物工程研究所 | 一种表达炭疽杆菌γ噬菌体裂解酶的方法及其专用基因 |
| DE102006061002A1 (de) * | 2006-12-22 | 2008-06-26 | Profos Ag | Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von gram-positiven Bakterien |
| US20110059514A1 (en) * | 2007-01-09 | 2011-03-10 | David Alexander Schofield | Yeast Biocatalysts for Degradation of Biowarfare Agents |
| CN101003569B (zh) * | 2007-01-19 | 2010-06-23 | 中国人民解放军军事医学科学院生物工程研究所 | 炭疽杆菌γ噬菌体裂解酶抗原表位及其突变体与应用 |
| WO2009045581A2 (en) * | 2007-06-15 | 2009-04-09 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Bacteriophage with enhanced lytic activity |
| EP2441834A1 (en) | 2007-10-01 | 2012-04-18 | Guild Associates, Inc. | Differentially Fluorescent Yeast Biosensors for the Detection and Biodegration of Chemical Agents |
| CA2711841A1 (en) | 2008-01-10 | 2009-09-03 | Trustees Of Boston University | Engineered bacteriophages as adjuvants for antimicrobial agents and compositions and methods of use thereof |
| US9157097B2 (en) * | 2008-09-25 | 2015-10-13 | Proteovec Holding, L.L.C. | Vectors for production of growth hormone |
| WO2010036979A2 (en) * | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Novel vectors for production of interferon |
| WO2010036976A2 (en) * | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Novel vectors for production of antibodies |
| CA2744909A1 (en) * | 2008-11-28 | 2010-06-03 | Warren H. Finlay | Bacteriophage compositions for treatment of bacterial infections |
| WO2010141135A2 (en) | 2009-03-05 | 2010-12-09 | Trustees Of Boston University | Bacteriophages expressing antimicrobial peptides and uses thereof |
| EP2417263B1 (en) * | 2009-04-09 | 2015-09-23 | ProteoVec Holding L.L.C. | Production of proteins using transposon-based vectors |
| DK2699253T3 (en) | 2011-04-21 | 2018-07-16 | Univ Rockefeller | STREPTOCOCCUS BACTERYPHAGIC LYSINES FOR THE DETECTION AND TREATMENT OF GRAM POSITIVE BACTERIES |
| US9279118B2 (en) | 2011-10-05 | 2016-03-08 | The Rockefeller University | Dimeric bacteriophage lysins |
| KR101339908B1 (ko) | 2011-11-11 | 2013-12-10 | 가천대학교 산학협력단 | 바실러스 세레우스에 대해 생육 억제능을 나타내는 신규의 박테리오파지 |
| BR112014027818B1 (pt) | 2012-05-09 | 2023-03-28 | Contrafect Corporation | Usos de composições compreendendo polipeptídeo de lisina para prevenção, ruptura ou tratamento de um biofilme bacteriano |
| RU2018121290A (ru) | 2012-05-09 | 2019-03-06 | Контрафект Корпорейшн | Комбинации лизина бактериофага и антибиотика против грам-положительных бактерий |
| UA119324C2 (uk) * | 2013-04-02 | 2019-06-10 | Теміс Медікер Лімітед | Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні |
| KR101765393B1 (ko) | 2015-11-05 | 2017-08-07 | 국방과학연구소 | 탄저균 특이 용균 단백질 b4의 제조 방법 및 탄저균에 의해 유발되는 질환의 치료 방법 |
| US11185555B2 (en) | 2016-04-11 | 2021-11-30 | Noah James Harrison | Method to kill pathogenic microbes in a patient |
| EP3454888B1 (en) | 2016-05-12 | 2021-02-24 | Contrafect Corporation | Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides |
| CN110868856A (zh) | 2017-07-12 | 2020-03-06 | 埃科莱布美国股份有限公司 | 在工业工艺中快速检测细菌孢子的方法 |
| US11421260B2 (en) | 2017-07-12 | 2022-08-23 | Ecolab Usa Inc. | Rapid approach for detection of bacterial spores |
| KR102146555B1 (ko) * | 2018-11-27 | 2020-08-20 | 국방과학연구소 | 탄저균 특이적 항균능을 갖는 약학적 조성물 및 이의 제조방법 |
| WO2021092362A1 (en) | 2019-11-07 | 2021-05-14 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Use of specific phages for the treatment of nontuberculous mycobacteria (ntm) infections |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US127215A (en) * | 1872-05-28 | Improvement in chemical compounds for destroying nicotine in tobacco | ||
| US6329156B1 (en) * | 1999-03-22 | 2001-12-11 | The Regents Of The University Of California | Method for screening inhibitors of the toxicity of Bacillus anthracis |
| US20020127215A1 (en) | 1999-09-14 | 2002-09-12 | Lawrence Loomis | Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections |
| GB0118009D0 (en) * | 2001-07-24 | 2001-09-19 | Regma Biotechnologies Ltd | Novel preparation |
-
2003
- 2003-05-19 JP JP2004538165A patent/JP2006513149A/ja active Pending
- 2003-05-19 EP EP03768500A patent/EP1501925A4/en not_active Withdrawn
- 2003-05-19 WO PCT/US2003/015719 patent/WO2004027020A2/en not_active Ceased
- 2003-05-19 CA CA002486280A patent/CA2486280A1/en not_active Abandoned
- 2003-05-19 AU AU2003291614A patent/AU2003291614A1/en not_active Abandoned
-
2004
- 2004-05-19 US US10/849,948 patent/US7402309B2/en not_active Expired - Lifetime
-
2008
- 2008-05-13 US US12/119,729 patent/US8580553B2/en not_active Expired - Fee Related
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