JP2006514820A5 - - Google Patents
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- JP2006514820A5 JP2006514820A5 JP2003586178A JP2003586178A JP2006514820A5 JP 2006514820 A5 JP2006514820 A5 JP 2006514820A5 JP 2003586178 A JP2003586178 A JP 2003586178A JP 2003586178 A JP2003586178 A JP 2003586178A JP 2006514820 A5 JP2006514820 A5 JP 2006514820A5
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- JP
- Japan
- Prior art keywords
- peptide
- seq
- group
- nos
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 40
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 150000001413 amino acids Chemical class 0.000 claims 10
- 239000012634 fragment Substances 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 3
- 125000003368 amide group Chemical group 0.000 claims 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 108091006116 chimeric peptides Proteins 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 230000008707 rearrangement Effects 0.000 claims 2
- 102000001490 Opioid Peptides Human genes 0.000 claims 1
- 108010093625 Opioid Peptides Proteins 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000003399 opiate peptide Substances 0.000 claims 1
- 108010091748 peptide A Proteins 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 230000005945 translocation Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/126,845 US20030181367A1 (en) | 1999-09-27 | 2002-04-19 | Conjugates of membrane translocating agents and pharmaceutically active agents |
| PCT/US2003/012543 WO2003089458A2 (en) | 2002-04-19 | 2003-04-21 | Conjugates of membrane translocating agents and pharmaceutically active agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010128982A Division JP5211109B2 (ja) | 2002-04-19 | 2010-06-04 | 膜転位剤および製薬学的有効成分の複合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514820A JP2006514820A (ja) | 2006-05-18 |
| JP2006514820A5 true JP2006514820A5 (https=) | 2006-07-06 |
Family
ID=29248426
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003586178A Withdrawn JP2006514820A (ja) | 2002-04-19 | 2003-04-21 | 膜転位剤および製薬学的有効成分の複合物 |
| JP2010128982A Expired - Fee Related JP5211109B2 (ja) | 2002-04-19 | 2010-06-04 | 膜転位剤および製薬学的有効成分の複合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010128982A Expired - Fee Related JP5211109B2 (ja) | 2002-04-19 | 2010-06-04 | 膜転位剤および製薬学的有効成分の複合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20030181367A1 (https=) |
| EP (2) | EP2431055A1 (https=) |
| JP (2) | JP2006514820A (https=) |
| AU (1) | AU2003228658A1 (https=) |
| CA (1) | CA2482719A1 (https=) |
| WO (1) | WO2003089458A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3192786B2 (ja) | 1992-12-15 | 2001-07-30 | 積水化学工業株式会社 | 長尺体の分離供給装置 |
| US6521737B1 (en) * | 1995-11-10 | 2003-02-18 | Elan Corporation, Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| US7176185B2 (en) | 2003-11-25 | 2007-02-13 | Tsrl, Inc. | Short peptide carrier system for cellular delivery of agent |
| DK2118123T3 (en) | 2007-01-31 | 2016-01-25 | Dana Farber Cancer Inst Inc | Stabilized p53 peptides and uses thereof |
| US8592377B2 (en) | 2007-03-28 | 2013-11-26 | President And Fellows Of Harvard College | Stitched polypeptides |
| US8586081B2 (en) * | 2007-09-20 | 2013-11-19 | University Of Massachusetts | Detoxified recombinant botulinum neurotoxin |
| ES2334315B1 (es) * | 2008-07-29 | 2011-02-28 | Universitat Pompeu Fabra | Peptidos con capacidad de penetracion celular y sus usos. |
| ES2711526T3 (es) | 2010-08-13 | 2019-05-06 | Aileron Therapeutics Inc | Macrociclos peptidomiméticos |
| TW201806968A (zh) | 2011-10-18 | 2018-03-01 | 艾利倫治療公司 | 擬肽巨環化合物 |
| EP2819688A4 (en) | 2012-02-15 | 2015-10-28 | Aileron Therapeutics Inc | TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES |
| BR112014020103A2 (pt) | 2012-02-15 | 2018-10-09 | Aileron Therapeutics, Inc. | macrociclos peptidomiméticos |
| PL2897620T3 (pl) | 2012-09-21 | 2020-11-02 | Intensity Therapeutics, Inc | Sposób leczenia nowotworu złośliwego |
| US9788765B2 (en) | 2012-09-28 | 2017-10-17 | Dexcom, Inc. | Zwitterion surface modifications for continuous sensors |
| WO2014071241A1 (en) | 2012-11-01 | 2014-05-08 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
| US9737250B2 (en) | 2013-03-15 | 2017-08-22 | Dexcom, Inc. | Membrane for continuous analyte sensors |
| EP3197478A4 (en) | 2014-09-24 | 2018-05-30 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| WO2016154058A1 (en) | 2015-03-20 | 2016-09-29 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| US11160871B2 (en) | 2015-10-28 | 2021-11-02 | Tarveda Therapeutics, Inc. | SSTR-targeted conjugates and particles and formulations thereof |
| CA3002099A1 (en) | 2015-12-30 | 2017-07-06 | Dexcom, Inc. | Diffusion resistance layer for analyte sensors |
| WO2025096604A1 (en) * | 2023-10-30 | 2025-05-08 | Adjuvia Therapeutics | Pharmaceutical composition and method of treating disease using a molecular complex assembled on astaxanthin core |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4847240A (en) | 1978-01-16 | 1989-07-11 | The Trustees Of Boston University | Method of effecting cellular uptake of molecules |
| US4244946A (en) * | 1979-06-11 | 1981-01-13 | The Salk Institute For Biological Studies | Water-soluble peptides affecting gonadal function |
| US4305872A (en) * | 1979-10-19 | 1981-12-15 | Kenneth Wingrove | Polypeptide derivatives |
| US4316891A (en) * | 1980-06-14 | 1982-02-23 | The Salk Institute For Biological Studies | Extended N-terminal somatostatin |
| US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US5449616A (en) * | 1990-05-23 | 1995-09-12 | University Of Iowa Research Foundation | Nucleic acid encoding dystrophin-associated protein |
| IE80466B1 (en) * | 1995-11-10 | 1998-07-29 | Elan Corp Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| US6361938B1 (en) * | 1996-11-08 | 2002-03-26 | Elan Corporation, Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| WO1998047913A2 (en) * | 1997-04-18 | 1998-10-29 | The University Of Medicine And Dentistry Of New Jersey | Inhibition of hiv-1 replication by a tat rna-binding domain peptide analog |
| JP4129298B2 (ja) | 1997-05-15 | 2008-08-06 | サイトジェン コーポレーション | 胃腸管（ｇｉｔ）輸送受容体に結合するランダムペプチド、及び関連した方法 |
| US6380370B1 (en) * | 1997-08-14 | 2002-04-30 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| IE970794A1 (en) * | 1997-09-24 | 2000-08-23 | Elan Corp Plc | Composition and method for enhancing paracellular transport across cell layers |
| US6423334B1 (en) * | 1997-10-01 | 2002-07-23 | Elan Corporation, Plc | Composition and method for enhancing transport across gastrointestinal tract cell layers |
| US6248558B1 (en) * | 1998-03-31 | 2001-06-19 | Vanderbilt University | Sequence and method for genetic engineering of proteins with cell membrane translocating activity |
| WO1999064449A2 (en) | 1998-06-10 | 1999-12-16 | The Queen's University Of Belfast | Cell-permeable peptide |
| CA2328457A1 (en) | 1998-06-20 | 1999-12-29 | Washington University | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
| US6451601B1 (en) | 1999-04-12 | 2002-09-17 | Modex Therapeutiques, S.A. | Transiently immortalized cells for use in gene therapy |
| US6593292B1 (en) | 1999-08-24 | 2003-07-15 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into epithelial tissues |
| WO2001027154A2 (en) * | 1999-09-27 | 2001-04-19 | Mahony Daniel J O | Membrane translocating peptide drug delivery system |
| JP2004535388A (ja) * | 2001-04-30 | 2004-11-25 | ターゲティッド ジェネティクス コーポレイション | 脂質含有薬物送達複合体およびそれらの生成方法 |
| DE60327890D1 (de) | 2002-12-11 | 2009-07-16 | Donaldson Co Inc | Z-filtermedien mit gegenstromreinigungssystemen und -verfahren |
| JP5008350B2 (ja) | 2006-07-05 | 2012-08-22 | 花王株式会社 | ガラス基板用の研磨液組成物 |
| US7981998B2 (en) | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
-
2002
- 2002-04-19 US US10/126,845 patent/US20030181367A1/en not_active Abandoned
-
2003
- 2003-04-21 JP JP2003586178A patent/JP2006514820A/ja not_active Withdrawn
- 2003-04-21 EP EP11182821A patent/EP2431055A1/en not_active Withdrawn
- 2003-04-21 CA CA002482719A patent/CA2482719A1/en not_active Abandoned
- 2003-04-21 EP EP03726420A patent/EP1575987A4/en not_active Withdrawn
- 2003-04-21 WO PCT/US2003/012543 patent/WO2003089458A2/en not_active Ceased
- 2003-04-21 AU AU2003228658A patent/AU2003228658A1/en not_active Abandoned
-
2004
- 2004-09-30 US US10/955,656 patent/US20050101762A1/en not_active Abandoned
-
2005
- 2005-12-16 US US11/303,372 patent/US7638599B2/en not_active Expired - Fee Related
-
2009
- 2009-12-23 US US12/645,922 patent/US8017727B2/en not_active Expired - Fee Related
-
2010
- 2010-06-04 JP JP2010128982A patent/JP5211109B2/ja not_active Expired - Fee Related
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