JP2008519592A5 - - Google Patents
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- Publication number
- JP2008519592A5 JP2008519592A5 JP2007540681A JP2007540681A JP2008519592A5 JP 2008519592 A5 JP2008519592 A5 JP 2008519592A5 JP 2007540681 A JP2007540681 A JP 2007540681A JP 2007540681 A JP2007540681 A JP 2007540681A JP 2008519592 A5 JP2008519592 A5 JP 2008519592A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- peptide
- lysine
- arginine
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 239000004472 Lysine Substances 0.000 claims 12
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 12
- 239000004475 Arginine Substances 0.000 claims 10
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 10
- 235000018417 cysteine Nutrition 0.000 claims 8
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 8
- 150000001413 amino acids Chemical class 0.000 claims 6
- 235000001014 amino acid Nutrition 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 108091006116 chimeric peptides Proteins 0.000 claims 4
- 108020001507 fusion proteins Proteins 0.000 claims 4
- 230000003834 intracellular effect Effects 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- 102000037865 fusion proteins Human genes 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- 150000008574 D-amino acids Chemical class 0.000 claims 1
- 101710118867 Maurocalcin Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0412045 | 2004-11-12 | ||
| FR0412045A FR2877946B1 (fr) | 2004-11-12 | 2004-11-12 | Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet |
| PCT/FR2005/002817 WO2006051224A1 (fr) | 2004-11-12 | 2005-11-14 | Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008519592A JP2008519592A (ja) | 2008-06-12 |
| JP2008519592A5 true JP2008519592A5 (https=) | 2008-12-18 |
| JP5416901B2 JP5416901B2 (ja) | 2014-02-12 |
Family
ID=34953760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007540681A Expired - Fee Related JP5416901B2 (ja) | 2004-11-12 | 2005-11-14 | 興味のある分子の細胞内位置決めのためのベクターとして用いられるマウロカルシン由来ペプチド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8207293B2 (https=) |
| EP (1) | EP1814905B1 (https=) |
| JP (1) | JP5416901B2 (https=) |
| CN (1) | CN101094863A (https=) |
| AU (1) | AU2005303623A1 (https=) |
| CA (1) | CA2586811A1 (https=) |
| FR (1) | FR2877946B1 (https=) |
| IL (1) | IL183022A0 (https=) |
| WO (1) | WO2006051224A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2537858A1 (en) | 2011-06-20 | 2012-12-26 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives | Small efficient cell penetrating peptides derived from the scorpion toxin maurocalcine |
| WO2014141124A1 (en) | 2013-03-13 | 2014-09-18 | Institut National De La Sante Et De La Recherche Medicale | Erk-pathway activating compound for preventing or treating leptin resistance |
| US9777274B2 (en) | 2013-03-15 | 2017-10-03 | Techulon Inc. | Antisense molecules for treatment of staphylococcus aureus infection |
| SG11201507141SA (en) | 2013-03-15 | 2015-10-29 | Techulon Inc | Antisense molecules for treatment of staphylococcus aureus infection |
| ES2699576T3 (es) | 2013-06-12 | 2019-02-11 | Pharis Biotec Gmbh | Péptidos con actividades antagonistas contra CXCR4 natural |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| CN105087492B (zh) * | 2015-07-16 | 2021-04-13 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 培养原代海马神经元的方法 |
| US11090358B2 (en) | 2015-09-09 | 2021-08-17 | Fred Hutchinson Cancer Research Center | Cartilage-homing peptides |
| AU2016366668A1 (en) * | 2015-12-11 | 2018-05-31 | Fred Hutchinson Cancer Research Center | Peptides for renal therapy |
| AU2018210157B2 (en) | 2017-01-18 | 2022-10-06 | Fred Hutchinson Cancer Center | Peptide compositions and methods of use thereof for disrupting TEAD interactions |
| EP3595699A4 (en) | 2017-03-16 | 2020-12-23 | Blaze Bioscience, Inc. | PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE |
| AU2018283161A1 (en) | 2017-06-15 | 2020-01-02 | Blaze Bioscience, Inc. | Renal-homing peptide conjugates and methods of use thereof |
| EP3727146A4 (en) | 2017-12-19 | 2021-10-06 | Blaze Bioscience, Inc. | TUMOR HOMING AND CELL-PENETANT PEPTIDE IMMUNO-ONCOLOGY AGENT COMPLEX AND METHOD OF USE |
| CN120459270A (zh) * | 2025-05-16 | 2025-08-12 | 中国人民解放军海军军医大学 | OpiCa1或其纳米脂质体在制备治疗和/或预防心肌纤维化相关疾病药物中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6051429A (en) | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| FR2739621B1 (fr) | 1995-10-05 | 1997-12-05 | Centre Nat Rech Scient | Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives |
| JP2002532383A (ja) * | 1998-09-15 | 2002-10-02 | ニゾ フード リサーチ | 生物学的液体からペプチドを製造する方法及びその方法で得られるペプチド |
| GB0005124D0 (en) * | 2000-03-03 | 2000-04-26 | Cellpep Sa | Maurocalcin,analogues thereof and their therapeutical uses |
| ES2340376T3 (es) * | 2002-06-10 | 2010-06-02 | Amylin Pharmaceuticals, Inc. | Desproteccion del azufre posterior a la escision para la sintesis convergente de proteinas mediante ligacion quimica. |
| SE0201863D0 (en) | 2002-06-18 | 2002-06-18 | Cepep Ab | Cell penetrating peptides |
-
2004
- 2004-11-12 FR FR0412045A patent/FR2877946B1/fr not_active Expired - Fee Related
-
2005
- 2005-11-14 US US11/719,171 patent/US8207293B2/en not_active Expired - Fee Related
- 2005-11-14 JP JP2007540681A patent/JP5416901B2/ja not_active Expired - Fee Related
- 2005-11-14 AU AU2005303623A patent/AU2005303623A1/en not_active Abandoned
- 2005-11-14 WO PCT/FR2005/002817 patent/WO2006051224A1/fr not_active Ceased
- 2005-11-14 CA CA002586811A patent/CA2586811A1/fr not_active Abandoned
- 2005-11-14 CN CNA2005800457088A patent/CN101094863A/zh active Pending
- 2005-11-14 EP EP05817457.4A patent/EP1814905B1/fr not_active Expired - Lifetime
-
2007
- 2007-05-06 IL IL183022A patent/IL183022A0/en unknown
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