JP2006512168A - 拡張期血行動態を監視するための方法と装置 - Google Patents
拡張期血行動態を監視するための方法と装置 Download PDFInfo
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- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
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Abstract
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Claims (39)
- 音響エネルギーを感知し、心音を示す音響センサ信号を作成するための音響センサと、
心臓の電気的事象を示す心臓信号を感知するための心臓感知回路と、
前記音響センサと前記心臓感知回路に結合され、前記音響センサ信号と心臓信号に基づいて選択された心音を検知するように構成された心音検知器と、
前記心音検知器に結合され、前記選択された心音に関連する少なくとも1つの所定のパラメータの値を生成するように構成されたパラメータ生成器と、
パラメータ生成器に結合され、前記少なくとも1つの所定のパラメータの値に基づいて、1つまたは複数のタイプの選択された心音に関連する少なくとも1つの傾向を作成し、解析するように構成された傾向解析器を備えるプロセッサと、
プロセッサに通信可能に結合され、少なくとも1つの傾向に基づいて決定された少なくとも1つの治療パラメータを有する少なくとも1つの心臓治療を行うように構成された治療回路とを備えるシステム。 - 前記音響センサが、加速度計を備える請求項1に記載のシステム。
- 前記音響センサが、マイクロフォンを備える請求項1に記載のシステム。
- 前記音響センサと前記心音検知器の間に結合され、
前記音響センサに結合された、前記音響センサ信号をデジタル化するためのデジタイザと、
前記デジタル化された音響センサ信号内での前記選択された心音の表示を強化するために、少なくとも1つのプログラム可能な遮断周波数を有する、前記デジタイザに結合されたバンド・パス・フィルタとを備える、
センサ・インタフェース・モジュールをさらに備える前記請求項のいずれか1項に記載のシステム。 - 前記バンド・パス・フィルタが、5から20Hzの範囲の低遮断周波数と、30から120Hzの範囲の高遮断周波数を備えるエンベロプ検知器タイプのフィルタを備える請求項4に記載のシステム。
- 前記心臓感知回路が、
前記心臓の電気的事象を検知するために前記感知増幅器に結合された心臓事象検知器と、
前記検知された心臓の電気的事象の選択された事象を表す事象マーカを生成するために前記心臓事象検知器に結合された事象マーカ生成器とを備える前記請求項のいずれか1項に記載のシステム。 - 前記心音検知器が、前記音響センサと前記心臓感知回路に結合されたゲーティング・モジュールを備え、前記ゲーティング・モジュールが、選択された心臓の電気的事象の1つの発生時間に基づいて、前記選択された心音の1つを検知するように時間調整された心音検知ウィンドウを生成するように構成された前記請求項のいずれか1項に記載のシステム。
- 前記パラメータ生成器が、
前記選択された心音の選択されたタイプにそれぞれ関連する振幅を測定するように構成された強度検知器と、
前記選択された心音の2つの選択されたタイプに関連する振幅のそれぞれの間の差を決定するように構成された相対強度検知器と、
前記選択された心音の選択されたタイプにそれぞれ関連する継続時間を測定するように構成された継続時間タイマと、
前記選択された心音の選択されたタイプと前記選択された心臓の電気的事象の選択されたタイプのそれぞれの間の時間間隔を測定するように構成された電気機械的間隔タイマと、
前記選択された心音の2つの選択されたタイプのそれぞれの間の時間間隔を測定するように構成された機械的間隔タイマと、
前記選択された心音の選択されたタイプに関連する基本周波数を計算するように構成された周波数解析器と
の少なくとも1つを備える測定モジュールを備える前記請求項のいずれか1項に記載のシステム。 - 前記パラメータ生成器が、前記測定モジュールに結合されたスクリーニング・モジュールをさらに備え、前記スクリーニング・モジュールが、前記少なくとも1つの所定のパラメータの生の値の間のノイズ値を排除するように構成され、前記ノイズ値が、背景ノイズが所定のレベルを超えるときに測定された、前記少なくとも1つの所定のパラメータの値を含む請求項8に記載のシステム。
- 前記スクリーニング・モジュールに結合された活動監視モジュールをさらに備え、その活動監視モジュールが、前記背景ノイズに関連する物理的活動を感知するための活動センサを備える請求項9に記載のシステム。
- 前記音響センサに結合された活動監視モジュールをさらに備え、その活動監視モジュールが、前記背景ノイズを示す活動レベル信号を作成するように構成されている請求項9に記載のシステム。
- 前記パラメータ生成器が、少なくとも1つの所定のパラメータのスクリーニングされた値を格納するために、前記スクリーニング・モジュールに結合されたメモリ回路をさらに備える請求項9から11のいずれか1項に記載のシステム。
- 前記パラメータ生成器に結合されたデータ取得タイマをさらに備え、前記データ取得タイマが、前記センサ・インタフェース・モジュール、前記心音検知器、周期的な基準で所定の継続時間のためのプロセッサの1つまたは複数を有効化する前記請求項のいずれか1項に記載のシステム。
- 傾向解析器に結合された警報信号生成器をさらに備え、前記警報信号生成器が、傾向解析の結果に基づいて所定の心臓状態を示す警報信号を生成するように構成されている前記請求項のいずれか1項に記載のシステム。
- 前記傾向解析器が、少なくとも1つの傾向を示す第1の入力と、閾値レベルを示す第2の入力と、前記傾向解析の結果を示す出力とを備える比較器を備える前記請求項のいずれか1項に記載のシステム。
- 前記傾向解析器が、第2の所定の時間の間、前記少なくとも1つの所定のパラメータの値に基づいて閾値レベルを生成するように構成された閾値生成器をさらに備える請求項15に記載のシステム。
- 前記治療回路が、少なくとも傾向と、前記選択された心音に関連する少なくとも1つの所定のパラメータの値に基づいて治療パラメータを決定するように所定の制御アルゴリズムを実行するように構成された治療コントローラを備える前記請求項のいずれか1項に記載のシステム。
- 少なくとも前記心臓感知回路、前記心音検知器、前記治療回路を収容する密封された缶を備える埋め込み可能なデバイスを備える前記請求項のいずれか1項に記載のシステム。
- 前記密封された缶が、前記音響センサをさらに収容する請求項18に記載のシステム。
- 前記埋め込み可能なデバイスに結合された近端部と心臓の中または周囲に配置された遠端部を有するリードをさらに備え、前記音響センサが、前記リードと前記遠端部またはその近くで接続されている請求項18に記載のシステム。
- 前記密封された缶が、前記パラメータ生成器をさらに収容する請求項18〜20のいずれか1項に記載のシステム。
- 前記密封された缶が、前記プロセッサをさらに収容する請求項18〜21のいずれか1項に記載のシステム。
- 遠隔リンクを介して埋め込み可能なデバイスに通信可能に結合された外部システムをさらに備え、前記外部システムがプロセッサを備える請求項18〜20のいずれか1項に記載のシステム。
- 前記外部システムが、前記パラメータ生成器をさらに備える請求項23に記載のシステム。
- 心音を示す音響センサ信号を作成するために音響エネルギーを感知するステップと、
心臓の電気的事象を示す少なくとも1つの心臓信号を感知するステップと、
選択された心音を検知するステップと、
選択された心音と選択された心臓事象に関連する少なくとも1つの所定のパラメータの値を生成するステップと、
前記少なくとも1つの所定のパラメータの選択された値を解析するステップであって、その選択された値が第1の所定の時間の間に検知された前記選択された心音の1つまたは複数のタイプに関連する、選択するステップと、
前記少なくとも1つの所定のパラメータの前記選択された値に基づいて少なくとも1つの傾向を作成するステップと、
前記少なくとも1つの傾向に基づいて決定された少なくとも1つのパラメータを有する少なくとも1つの治療を行うステップと
を含む方法。 - 音響エネルギーを感知するステップが、前記音響エネルギーを示す加速度信号を感知することを含む請求項25に記載の方法。
- 第3心音(S3)と第4心音(S4)の検知を容易にする少なくとも1つの遮断周波数を決定するステップと、
前記少なくとも1つの遮断周波数をフィルタにプログラミングするステップと、
前記音響センサ信号内のS3、S4の表示を強化するために前記音響センサ信号をフィルタリングするステップとをさらに含む請求項25、26のいずれか1項に記載の方法。 - 少なくとも1つの心臓信号を検知するステップが、
心房収縮と心室収縮を含む心臓の電気的事象を検知するステップと、
前記検知された心臓の電気的事象の選択された事象を表す事象マーカを生成するステップとを含む請求項25〜27のいずれか1項に記載の方法。 - 前記選択された心音を検知するステップが、前記選択された心臓の電気的事象の1つの発生時間に基づいて前記選択された心音の1つを検知するようにそれぞれ時間調整された心音検知ウィンドウを生成するステップを含む請求項25〜28のいずれか1項に記載の方法。
- 少なくとも1つの所定のパラメータの値を生成することが、
前記選択された心音の選択されたタイプにそれぞれ関連する振幅と、
前記選択された心音の2つの選択されたタイプに関連する振幅のそれぞれの間の差である相対強度と、
前記選択された心音の選択されたタイプにそれぞれ関連する継続時間と、
前記選択された心音の選択されたタイプと前記選択された心臓の電気的事象の選択されたタイプのそれぞれの間の電気機械的時間間隔と、
前記選択された心音の2つの選択されたタイプのそれぞれ間の機械的時間間隔と、
前記選択された心音の選択されたタイプにそれぞれ関連する基本周波数の、少なくとも1つを生成するステップを含む請求項25〜29のいずれか1項に記載の方法。 - 少なくとも1つの所定のパラメータの値を生成するステップが、
第3心音(S3)の振幅と、
第4心音(S4)の振幅と、
S3のS4に対する強度と、
S3の継続時間と、
S4の継続時間と、
S3とそれに隣接する次の心房収縮との間の時間間隔と、
S4とそれに隣接する前の心房収縮との間の時間間隔と、
S3の開始と第2心音(S2)の間の時間間隔と、
S3の基本周波数と、
S4の基本周波数の、少なくとも1つの値を生成するステップを含む請求項25〜30のいずれか1項に記載の方法。 - 前記少なくとも1つの所定のパラメータの値を生成するステップが、背景ノイズが所定のレベルを超えているときに測定された少なくとも1つの所定のパラメータの値を含むノイズ値をスクリーニングするステップをさらに含む請求項30、31のいずれかに記載の方法。
- 前記ノイズ値をスクリーニングするステップが、前記背景ノイズを示す物理的活動レベルを感知するステップを含む請求項32に記載の方法。
- 少なくとも1つの所定のパラメータの値を生成するステップが、所定の周期的な基準で、所定のデータ取得持続時間の間、前記少なくとも1つの所定のパラメータの値を生成するステップを含む請求項25〜33のいずれか1項に記載の方法。
- 前記少なくとも1つの傾向に基づいて所定の心臓状態を示す警報信号を生成するステップをさらに備える請求項25〜34のいずれか1項に記載の方法。
- 警報信号を生成するステップが、前記少なくとも1つの傾向に関連する量を所定の閾値レベルと比較するステップを含む請求項35に記載の方法。
- 前記警報信号を生成するステップが、第2の所定の時間中に測定された少なくとも1つの所定のパラメータの値に基づいて閾値を生成するステップを含む請求項36に記載の方法。
- 前記警報信号を生成するステップが、収縮期充填パターンの1つの変化を示す警報信号を生成するステップを含む請求項35〜37のいずれか1項に記載の方法。
- 前記少なくとも1つの傾向を作成するステップが、第3心音(S3)および第4心音(S4)の少なくとも1つに関連する少なくとも1つの傾向を作成するステップを含む請求項25〜38のいずれか1項に記載の方法。
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2003
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- 2003-12-30 JP JP2004565783A patent/JP4576236B2/ja not_active Expired - Fee Related
- 2003-12-30 EP EP03800278A patent/EP1581302B1/en not_active Expired - Lifetime
- 2003-12-30 EP EP10158651.9A patent/EP2223718B1/en not_active Expired - Lifetime
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US8597197B2 (en) | 2006-11-20 | 2013-12-03 | Cardiac Pacemakers, Inc. | Monitoring of heart sounds |
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US10729909B2 (en) | 2006-11-29 | 2020-08-04 | Cardiac Pacemakers, Inc. | Adaptive sampling of heart sounds |
US8332034B2 (en) | 2007-04-17 | 2012-12-11 | Cardiac Pacemakers, Inc. | Heart sound tracking system and method |
US9049981B2 (en) | 2007-04-17 | 2015-06-09 | Cardiac Pacemakers, Inc. | Heart sound tracking system and method |
US9364193B2 (en) | 2007-04-17 | 2016-06-14 | Cardiac Pacemakers, Inc. | Heart sound tracking system and method |
JP2010524564A (ja) * | 2007-04-17 | 2010-07-22 | カーディアック ペースメイカーズ, インコーポレイテッド | 心音追跡システムおよび心音追跡方法 |
WO2010134388A1 (ja) * | 2009-05-20 | 2010-11-25 | Mihara Makoto | 生体情報モニタリングシステム |
JP2015188512A (ja) * | 2014-03-27 | 2015-11-02 | 旭化成株式会社 | 心疾患診断装置、心音解析プログラム、および、媒体 |
JP2015188511A (ja) * | 2014-03-27 | 2015-11-02 | 旭化成株式会社 | 心疾患診断装置、心音解析プログラムおよび媒体 |
WO2021242026A1 (ko) * | 2020-05-28 | 2021-12-02 | 주식회사 반달컴퍼니 | 반려 동물의 생체 정보를 측정하기 위한 장치 |
KR20210147858A (ko) * | 2020-05-28 | 2021-12-07 | 주식회사 반달컴퍼니 | 반려 동물의 생체 정보를 측정하기 위한 장치 |
KR102476015B1 (ko) * | 2020-05-28 | 2022-12-09 | 주식회사 반달컴퍼니 | 반려 동물의 생체 정보를 측정하기 위한 장치 |
Also Published As
Publication number | Publication date |
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ATE470475T1 (de) | 2010-06-15 |
WO2004060483A1 (en) | 2004-07-22 |
US20040127792A1 (en) | 2004-07-01 |
EP2223718B1 (en) | 2014-04-02 |
EP2223718A1 (en) | 2010-09-01 |
EP1581302B1 (en) | 2010-06-09 |
AU2003300013A1 (en) | 2004-07-29 |
EP1581302A1 (en) | 2005-10-05 |
US7972275B2 (en) | 2011-07-05 |
JP4576236B2 (ja) | 2010-11-04 |
US20120041317A1 (en) | 2012-02-16 |
US8636669B2 (en) | 2014-01-28 |
US8403860B2 (en) | 2013-03-26 |
US20070066913A1 (en) | 2007-03-22 |
US20110098588A1 (en) | 2011-04-28 |
US8048001B2 (en) | 2011-11-01 |
DE60332960D1 (de) | 2010-07-22 |
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