JP2006512097A5 - - Google Patents
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- Publication number
- JP2006512097A5 JP2006512097A5 JP2005510053A JP2005510053A JP2006512097A5 JP 2006512097 A5 JP2006512097 A5 JP 2006512097A5 JP 2005510053 A JP2005510053 A JP 2005510053A JP 2005510053 A JP2005510053 A JP 2005510053A JP 2006512097 A5 JP2006512097 A5 JP 2006512097A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- nucleic acid
- ctla
- acid sequence
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43626802P | 2002-12-23 | 2002-12-23 | |
| US46660703P | 2003-04-30 | 2003-04-30 | |
| PCT/US2003/041053 WO2004058801A2 (en) | 2002-12-23 | 2003-12-22 | Modified vaccinia ankara expressing p53 in cancer immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006512097A JP2006512097A (ja) | 2006-04-13 |
| JP2006512097A5 true JP2006512097A5 (enExample) | 2007-02-15 |
Family
ID=32685446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005510053A Withdrawn JP2006512097A (ja) | 2002-12-23 | 2003-12-22 | 癌免疫療法におけるｐ５３を発現する改変・ワクシニア・アンカラ |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7256037B2 (enExample) |
| EP (1) | EP1575611A4 (enExample) |
| JP (1) | JP2006512097A (enExample) |
| AU (1) | AU2003297499A1 (enExample) |
| CA (1) | CA2511625A1 (enExample) |
| WO (1) | WO2004058801A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10100316B2 (en) * | 2002-11-21 | 2018-10-16 | Archemix Llc | Aptamers comprising CPG motifs |
| EP1601681A4 (en) * | 2003-03-12 | 2006-11-29 | Univ Duke | oligonucleotide mimetics |
| US7674456B2 (en) * | 2004-06-14 | 2010-03-09 | Charles Wiseman | Breast cancer cell lines and uses thereof |
| CN101128217B (zh) | 2005-02-23 | 2012-04-25 | 巴法里安诺迪克有限公司 | 改良的痘病毒快速诱导抗痘病毒或其它传染物的免疫力的用途 |
| WO2007008463A2 (en) * | 2005-07-07 | 2007-01-18 | Coley Pharmaceutical Group, Inc. | Anti-ctla-4 antibody and cpg-motif-containing synthetic oligodeoxynucleotide combination therapy for cancer treatment |
| CN1919873B (zh) * | 2005-08-25 | 2012-05-30 | 北京沙东生物技术有限公司 | 包含人HSP70 ATPase结构域与哺乳动物p53蛋白的融合蛋白及其应用 |
| WO2007123737A2 (en) * | 2006-03-30 | 2007-11-01 | University Of California | Methods and compositions for localized secretion of anti-ctla-4 antibodies |
| CN101678091A (zh) * | 2007-05-24 | 2010-03-24 | 葛兰素史密丝克莱恩生物有限公司 | 冷冻干燥的抗原组合物 |
| US7998488B2 (en) * | 2008-11-14 | 2011-08-16 | Baxter International Inc. | Vaccine formulations and uses thereof |
| WO2015077717A1 (en) | 2013-11-25 | 2015-05-28 | The Broad Institute Inc. | Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status |
| WO2015085147A1 (en) | 2013-12-05 | 2015-06-11 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| JP7060324B2 (ja) | 2013-12-20 | 2022-04-26 | ザ・ブロード・インスティテュート・インコーポレイテッド | ネオ抗原ワクチンによる併用療法 |
| US10975442B2 (en) | 2014-12-19 | 2021-04-13 | Massachusetts Institute Of Technology | Molecular biomarkers for cancer immunotherapy |
| EP3234130B1 (en) | 2014-12-19 | 2020-11-25 | The Broad Institute, Inc. | Methods for profiling the t-cell- receptor repertoire |
| CA2975432A1 (en) | 2015-02-13 | 2016-08-18 | Transgene Sa | Immunotherapeutic vaccine and antibody combination therapy |
| EP4122492A1 (en) | 2015-02-25 | 2023-01-25 | Memorial Sloan Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| KR20180006916A (ko) | 2015-04-17 | 2018-01-19 | 메모리얼 슬로안-케터링 캔서 센터 | 고형 종양에 대한 면역치료제로서 mva 또는 mva델타e3l의 용도 |
| JP6913032B2 (ja) | 2015-05-20 | 2021-08-04 | ザ・ブロード・インスティテュート・インコーポレイテッド | 共通ネオ抗原 |
| US20190038713A1 (en) | 2015-11-07 | 2019-02-07 | Multivir Inc. | Compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer |
| CN109152815B (zh) | 2016-02-25 | 2022-10-18 | 纪念斯隆凯特琳癌症中心 | 用于癌症免疫治疗的具有胸苷激酶缺失和具有或不具有人flt3l或gm-csf表达的复制型减毒痘苗病毒 |
| WO2017147554A2 (en) | 2016-02-25 | 2017-08-31 | Memorial Sloan-Kettering Cancer Center | Recombinant mva or mvadele3l expressing human flt3l and use thereof as immuno-therapeutic agents against solid tumors |
| US11602554B2 (en) | 2016-12-08 | 2023-03-14 | City Of Hope | P53-targeting vaccines and pd-1 pathway inhibitors and methods of use thereof |
| WO2018111902A1 (en) | 2016-12-12 | 2018-06-21 | Multivir Inc. | Methods and compositions comprising viral gene therapy and an immune checkpoint inhibitor for treatment and prevention of cancer and infectious diseases |
| WO2018112470A1 (en) * | 2016-12-16 | 2018-06-21 | The Brigham And Women's Hospital, Inc. | Co-delivery of nucleic acids for simultaneous suppression and expression of target genes |
| EP3574116A1 (en) | 2017-01-24 | 2019-12-04 | The Broad Institute, Inc. | Compositions and methods for detecting a mutant variant of a polynucleotide |
| CN111107872A (zh) | 2017-05-12 | 2020-05-05 | 纪念斯隆-凯特林癌症中心 | 有用于癌症免疫疗法的牛痘病毒突变体 |
| CN111556760A (zh) * | 2017-11-06 | 2020-08-18 | 纪念斯隆-凯特林癌症中心 | 作为疫苗免疫佐剂的热灭活的牛痘病毒 |
| CA3094329A1 (en) | 2018-03-19 | 2020-02-20 | Multivir Inc. | Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer |
| CA3112654A1 (en) | 2018-09-15 | 2020-03-19 | Memorial Sloan Kettering Cancer Center | Recombinant poxviruses for cancer immunotherapy |
| WO2020077039A1 (en) * | 2018-10-12 | 2020-04-16 | Synergene Therapeutics, Inc. | Methods for reducing side effects of immunotherapy |
| WO2021113644A1 (en) | 2019-12-05 | 2021-06-10 | Multivir Inc. | Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer |
| CA3183081A1 (en) * | 2020-06-24 | 2021-12-30 | Arnold Levine | Combination therapy for treatment of cancer |
| CN115537399B (zh) * | 2022-09-22 | 2025-02-11 | 沈阳药科大学 | 修饰化外泌体及其制法和外泌体联合pd-1抗体的原位喷雾水凝胶和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341245C (en) * | 1988-01-12 | 2001-06-05 | F. Hoffmann-La Roche Ag | Recombinant vaccinia virus mva |
| US6410010B1 (en) * | 1992-10-13 | 2002-06-25 | Board Of Regents, The University Of Texas System | Recombinant P53 adenovirus compositions |
| US6045802A (en) * | 1994-10-03 | 2000-04-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
| EP1594970B1 (en) * | 2003-02-18 | 2008-07-30 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Recombinant mva and method for generation thereof |
-
2003
- 2003-12-22 CA CA002511625A patent/CA2511625A1/en not_active Abandoned
- 2003-12-22 WO PCT/US2003/041053 patent/WO2004058801A2/en not_active Ceased
- 2003-12-22 EP EP03814346A patent/EP1575611A4/en not_active Withdrawn
- 2003-12-22 JP JP2005510053A patent/JP2006512097A/ja not_active Withdrawn
- 2003-12-22 AU AU2003297499A patent/AU2003297499A1/en not_active Abandoned
- 2003-12-23 US US10/746,558 patent/US7256037B2/en not_active Expired - Lifetime
-
2007
- 2007-05-21 US US11/805,180 patent/US7563448B2/en not_active Expired - Lifetime
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