JP2006506327A5 - - Google Patents
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- JP2006506327A5 JP2006506327A5 JP2004508111A JP2004508111A JP2006506327A5 JP 2006506327 A5 JP2006506327 A5 JP 2006506327A5 JP 2004508111 A JP2004508111 A JP 2004508111A JP 2004508111 A JP2004508111 A JP 2004508111A JP 2006506327 A5 JP2006506327 A5 JP 2006506327A5
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| EP1742662A2 (en) * | 2004-05-03 | 2007-01-17 | Astellas Pharma Inc. | Combination of prostaglandin e2 receptor antagonists and renin-angiotensin system inhibitors for treating renal diseases |
| US20060115785A1 (en) | 2004-11-30 | 2006-06-01 | Chunhua Li | Systems and methods for intra-oral drug delivery |
| WO2007146187A2 (en) * | 2006-06-06 | 2007-12-21 | Reika Ortho Technologies, Inc. | Transduction orthodontic devices |
| CN101041687B (zh) * | 2007-02-28 | 2010-09-29 | 长春博泰医药生物技术有限责任公司 | Pge2特异结合的噬菌体环七肽及筛选方法和合成肽的用途 |
| JPWO2010087425A1 (ja) | 2009-01-30 | 2012-08-02 | 国立大学法人京都大学 | 前立腺癌の進行抑制剤および進行抑制方法 |
| JP5273689B2 (ja) | 2010-09-29 | 2013-08-28 | 株式会社エヌビィー健康研究所 | ヒトプロスタグランジンｅ２受容体ｅｐ４に対する抗体 |
| HRP20180703T1 (hr) | 2013-06-12 | 2018-06-15 | Kaken Pharmaceutical Co., Ltd. | Derivat 4-alkinil imidazola i lijek koji kao aktivni sastojak sadrži isti |
| TW201623277A (zh) * | 2014-03-26 | 2016-07-01 | 安斯泰來製藥股份有限公司 | 醯胺化合物 |
| WO2016196400A1 (en) | 2015-05-29 | 2016-12-08 | Purdue Research Foundation | Bone fracture repair by targeting of agents that promote bone healing |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| CN110621671A (zh) | 2017-05-18 | 2019-12-27 | 爱杜西亚药品有限公司 | 作为pge2受体调节剂的苯并呋喃及苯并噻吩衍生物 |
| EP3625224B1 (en) | 2017-05-18 | 2021-08-04 | Idorsia Pharmaceuticals Ltd | N-substituted indole derivatives |
| PL3625228T3 (pl) | 2017-05-18 | 2021-12-20 | Idorsia Pharmaceuticals Ltd | Pochodne pirymidyny jako modulatory receptora pge2 |
| CN110621667A (zh) | 2017-05-18 | 2019-12-27 | 爱杜西亚药品有限公司 | 嘧啶衍生物 |
| EA201992676A1 (ru) | 2017-05-18 | 2020-05-06 | Идорсия Фармасьютиклз Лтд | Фенильные производные в качестве модуляторов pge2 рецепторов |
| US20230390303A1 (en) | 2020-11-13 | 2023-12-07 | Ono Pharmaceutical Co., Ltd. | Cancer treatment by combination of ep4 antagonist and immune checkpoint inhibitor |
| EP4603087A1 (en) * | 2022-11-21 | 2025-08-20 | Kyowa Hakko Bio Co., Ltd. | Prophylactic or therapeutic agent for acute kidney injury induced by anticancer agent |
| WO2025115623A1 (ja) * | 2023-11-28 | 2025-06-05 | 新田ゼラチン株式会社 | プロスタグランジンｅ２産生抑制剤、それを含む飲食品、プロスタグランジンｅ２産生抑制方法、およびプロスタグランジンｅ２産生抑制剤の製造方法 |
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| US5605814A (en) * | 1993-08-31 | 1997-02-25 | Merck Frosst Canada Inc. | DNA encoding human prostaglandin receptor EP2 |
| TWI247606B (en) * | 1999-11-24 | 2006-01-21 | Ono Pharmaceutical Co | Treating agent for osteopenic diseases |
| ATE298346T1 (de) * | 1999-12-06 | 2005-07-15 | Chu Sainte Justine | Verbindungen zur behandlung von abnormaler glomerularer filtration, patent ductus arteriosus und osteoporosis |
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- 2003-05-23 EP EP03727063A patent/EP1506220A1/en not_active Withdrawn
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