JP2006506327A - プロスタグランジンｅ２の受容体サブタイプｅｐ４のアンタゴニスト・ポリペプチド - Google Patents
プロスタグランジンｅ２の受容体サブタイプｅｐ４のアンタゴニスト・ポリペプチド Download PDFInfo
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- JP2006506327A JP2006506327A JP2004508111A JP2004508111A JP2006506327A JP 2006506327 A JP2006506327 A JP 2006506327A JP 2004508111 A JP2004508111 A JP 2004508111A JP 2004508111 A JP2004508111 A JP 2004508111A JP 2006506327 A JP2006506327 A JP 2006506327A
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Classifications
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- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
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- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
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| US38233602P | 2002-05-23 | 2002-05-23 | |
| PCT/CA2003/000771 WO2003099857A1 (en) | 2002-05-23 | 2003-05-23 | Antagonistic peptides of prostaglandin e2 receptor subtype ep4 |
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| Publication Number | Publication Date |
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| JP2006506327A true JP2006506327A (ja) | 2006-02-23 |
| JP2006506327A5 JP2006506327A5 (enExample) | 2006-09-14 |
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| Country | Link |
|---|---|
| US (1) | US20040023853A1 (enExample) |
| EP (1) | EP1506220A1 (enExample) |
| JP (1) | JP2006506327A (enExample) |
| CN (1) | CN1662551A (enExample) |
| AU (1) | AU2003233297A1 (enExample) |
| BR (1) | BR0311247A (enExample) |
| CA (1) | CA2485485A1 (enExample) |
| WO (1) | WO2003099857A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024111404A1 (ja) * | 2022-11-21 | 2024-05-30 | 協和発酵バイオ株式会社 | 抗がん剤により誘発される急性腎障害の予防又は治療剤 |
| WO2025115623A1 (ja) * | 2023-11-28 | 2025-06-05 | 新田ゼラチン株式会社 | プロスタグランジンｅ２産生抑制剤、それを含む飲食品、プロスタグランジンｅ２産生抑制方法、およびプロスタグランジンｅ２産生抑制剤の製造方法 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2565628A1 (en) * | 2004-05-03 | 2005-11-10 | Astellas Pharma Inc. | The combination of prostaglandin e2 receptor antagonist and renin-angiotensin system inhibitor for treating renal diseases |
| US20060115785A1 (en) * | 2004-11-30 | 2006-06-01 | Chunhua Li | Systems and methods for intra-oral drug delivery |
| CN101500504B (zh) * | 2006-06-06 | 2012-06-13 | 雷卡奥索技术公司 | 转导正畸矫正装置 |
| CN101041687B (zh) * | 2007-02-28 | 2010-09-29 | 长春博泰医药生物技术有限责任公司 | Pge2特异结合的噬菌体环七肽及筛选方法和合成肽的用途 |
| WO2010087425A1 (ja) | 2009-01-30 | 2010-08-05 | 国立大学法人京都大学 | 前立腺癌の進行抑制剤および進行抑制方法 |
| ES2537017T3 (es) | 2010-09-29 | 2015-06-01 | Nb Health Laboratory Co. Ltd. | Anticuerpo dirigido contra el receptor EP4 de la prostaglandina E2 humano |
| CN105431416B (zh) | 2013-06-12 | 2019-01-08 | 科研制药株式会社 | 4-炔基咪唑衍生物和含有其作为有效成分的药物 |
| TW201623277A (zh) * | 2014-03-26 | 2016-07-01 | 安斯泰來製藥股份有限公司 | 醯胺化合物 |
| US10279044B2 (en) | 2015-05-29 | 2019-05-07 | Purdue Research Foundation | Bone fracture repair by targeting of agents that promote bone healing |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| KR102612140B1 (ko) | 2017-05-18 | 2023-12-08 | 이도르시아 파마슈티컬스 리미티드 | 피리미딘 유도체 |
| PE20191787A1 (es) | 2017-05-18 | 2019-12-24 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituidos |
| AR111808A1 (es) | 2017-05-18 | 2019-08-21 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores del receptor de pge2 |
| EA201992676A1 (ru) | 2017-05-18 | 2020-05-06 | Идорсия Фармасьютиклз Лтд | Фенильные производные в качестве модуляторов pge2 рецепторов |
| US11325899B2 (en) | 2017-05-18 | 2022-05-10 | Idorsia Pharmaceuticals Ltd | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators |
| JP7816164B2 (ja) | 2020-11-13 | 2026-02-18 | 小野薬品工業株式会社 | Ｅｐ４拮抗薬と免疫チェックポイント阻害物質との併用によるがん治療 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5605814A (en) * | 1993-08-31 | 1997-02-25 | Merck Frosst Canada Inc. | DNA encoding human prostaglandin receptor EP2 |
| TWI247606B (en) * | 1999-11-24 | 2006-01-21 | Ono Pharmaceutical Co | Treating agent for osteopenic diseases |
| WO2001042281A1 (en) * | 1999-12-06 | 2001-06-14 | Hôpital Sainte-Justine | Compositions for treating abnormalities in glomerular filtration, patent ductus arteriosus and osteoporosis |
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2003
- 2003-05-23 CA CA002485485A patent/CA2485485A1/en not_active Abandoned
- 2003-05-23 EP EP03727063A patent/EP1506220A1/en not_active Withdrawn
- 2003-05-23 CN CN038146851A patent/CN1662551A/zh active Pending
- 2003-05-23 US US10/444,516 patent/US20040023853A1/en not_active Abandoned
- 2003-05-23 WO PCT/CA2003/000771 patent/WO2003099857A1/en not_active Ceased
- 2003-05-23 BR BR0311247-0A patent/BR0311247A/pt not_active IP Right Cessation
- 2003-05-23 JP JP2004508111A patent/JP2006506327A/ja active Pending
- 2003-05-23 AU AU2003233297A patent/AU2003233297A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024111404A1 (ja) * | 2022-11-21 | 2024-05-30 | 協和発酵バイオ株式会社 | 抗がん剤により誘発される急性腎障害の予防又は治療剤 |
| WO2025115623A1 (ja) * | 2023-11-28 | 2025-06-05 | 新田ゼラチン株式会社 | プロスタグランジンｅ２産生抑制剤、それを含む飲食品、プロスタグランジンｅ２産生抑制方法、およびプロスタグランジンｅ２産生抑制剤の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1506220A1 (en) | 2005-02-16 |
| CA2485485A1 (en) | 2003-12-04 |
| AU2003233297A2 (en) | 2003-12-12 |
| CN1662551A (zh) | 2005-08-31 |
| WO2003099857B1 (en) | 2004-02-19 |
| BR0311247A (pt) | 2005-03-15 |
| US20040023853A1 (en) | 2004-02-05 |
| WO2003099857A1 (en) | 2003-12-04 |
| AU2003233297A1 (en) | 2003-12-12 |
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