JP2006502963A5 - - Google Patents
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- Publication number
- JP2006502963A5 JP2006502963A5 JP2003564026A JP2003564026A JP2006502963A5 JP 2006502963 A5 JP2006502963 A5 JP 2006502963A5 JP 2003564026 A JP2003564026 A JP 2003564026A JP 2003564026 A JP2003564026 A JP 2003564026A JP 2006502963 A5 JP2006502963 A5 JP 2006502963A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- furan
- oxo
- hydroxy
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35393902P | 2002-01-31 | 2002-01-31 | |
| PCT/US2003/002766 WO2003064403A1 (en) | 2002-01-31 | 2003-01-30 | Furanone derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006502963A JP2006502963A (ja) | 2006-01-26 |
| JP2006502963A5 true JP2006502963A5 (https=) | 2006-04-20 |
Family
ID=27663268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003564026A Pending JP2006502963A (ja) | 2002-01-31 | 2003-01-30 | フラノン誘導体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6667330B2 (https=) |
| EP (1) | EP1478634A4 (https=) |
| JP (1) | JP2006502963A (https=) |
| AU (1) | AU2003207750A2 (https=) |
| CA (1) | CA2474871A1 (https=) |
| MX (1) | MXPA04007292A (https=) |
| NZ (1) | NZ534305A (https=) |
| WO (1) | WO2003064403A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7985771B2 (en) * | 2002-01-31 | 2011-07-26 | Monsanto Technology Llc | Furanone derivatives |
| US20040156874A1 (en) * | 2003-02-11 | 2004-08-12 | Bradley Pharmaceuticals, Inc. | Urea- a topical anti-inflammatory |
| TW200600091A (en) * | 2004-05-21 | 2006-01-01 | Telik Inc | Sulfonylethyl phosphorodiamidates |
| ES2619303T3 (es) | 2005-06-01 | 2017-06-26 | Edison Pharmaceuticals, Inc. | Productos terapéuticos redox activos para el tratamiento de enfermedades mitocondriales y otras afecciones y modulación de biomarcadores energéticos |
| WO2007100652A2 (en) | 2006-02-22 | 2007-09-07 | Edison Pharmaceuticals, Inc. | Side chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| EA038941B1 (ru) | 2007-11-06 | 2021-11-12 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | ПРОИЗВОДНЫЕ 4-(п-ХИНОНИЛ)-2-ГИДРОКСИБУТАНАМИДА ДЛЯ ЛЕЧЕНИЯ МИТОХОНДРИАЛЬНЫХ ЗАБОЛЕВАНИЙ |
| US8952071B2 (en) | 2008-01-08 | 2015-02-10 | Edison Pharmaceuticals, Inc. | (Het)aryl-p-quinone derivatives for treatment of mitochondrial diseases |
| WO2009111576A2 (en) | 2008-03-05 | 2009-09-11 | Edison Pharmaceuticals, Inc. | 2-SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES |
| JP5798481B2 (ja) | 2008-06-25 | 2015-10-21 | エジソン ファーマシューティカルズ， インコーポレイテッド | 酸化ストレス疾患を治療するための２−ヘテロシクリルアミノアルキル−（ｐ−キノン）誘導体 |
| MX363223B (es) | 2008-09-10 | 2019-03-15 | Bioelectron Tech Corp | Tratamiento de trastornos generalizados del desarrollo con terapeuticos con actividad redox. |
| EP2362726B1 (en) | 2008-10-14 | 2018-08-08 | Bioelectron Technology Corporation | Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells |
| ES2553557T3 (es) | 2008-10-28 | 2015-12-10 | Edison Pharmaceuticals, Inc. | Proceso para la producción de alfa-tocotrienol y derivados |
| CA2777479C (en) | 2009-04-28 | 2017-10-17 | Ptc Therapeutics, Inc. | Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones |
| EP2734512B1 (en) | 2011-07-19 | 2019-11-20 | Bioelectron Technology Corporation | Methods for selective oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols |
| EP3345596B1 (en) * | 2012-09-21 | 2021-01-20 | Rhode Island Hospital | Inhibitors of beta-hydrolase for treatment of cancer |
| US9868711B2 (en) | 2013-03-15 | 2018-01-16 | Bioelectron Technology Corporation | Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders |
| US9670170B2 (en) | 2013-03-15 | 2017-06-06 | Bioelectron Technology Corporation | Resorufin derivatives for treatment of oxidative stress disorders |
| US9296712B2 (en) | 2013-03-15 | 2016-03-29 | Edison Pharmaceuticals, Inc. | Resorufin derivatives for treatment of oxidative stress disorders |
| DK3233786T3 (da) | 2014-12-16 | 2022-05-09 | Ptc Therapeutics Inc | Polymorfe og amorfe former af (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6- dioxocyclohexa-1,4-dienyl)butanamid |
| WO2017106786A1 (en) | 2015-12-16 | 2017-06-22 | Bioelectron Technology Corporation | Improved methods for enriching alpha-tocotrienol from mixed tocol compositions |
| US10703701B2 (en) | 2015-12-17 | 2020-07-07 | Ptc Therapeutics, Inc. | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| JP2018083799A (ja) | 2016-11-15 | 2018-05-31 | バイオエレクトロン テクノロジー コーポレイション | ２−置換アミノ−ナフト［１，２−ｄ］イミダゾール−５−オン化合物またはその製薬学上許容される塩 |
| TN2021000075A1 (en) | 2018-10-17 | 2023-01-05 | Ptc Therapeutics Inc | 2,3,5-TRIMETHYL-6-NONYLCYCLOHEXA-2,5-DIENE-1,4-DIONE FOR SUPPRESSING AND TREATING α-SYNUCLEINOPATHIES, TAUOPATHIES, AND OTHER DISORDERS |
| MX2024000445A (es) | 2021-07-08 | 2024-04-05 | Ptc Therapeutics Inc | Composiciones farmaceuticas que comprenden 2,3,5-trimetil-6-nonilc iclohexa-2,5-dieno-1,4-diona. |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4875564A (https=) | 1972-01-08 | 1973-10-11 | ||
| JPS4988862A (https=) | 1972-12-29 | 1974-08-24 | ||
| JPH06100445A (ja) | 1992-07-06 | 1994-04-12 | Banyu Pharmaceut Co Ltd | 抗腫瘍剤 |
| US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5464865A (en) * | 1993-12-22 | 1995-11-07 | Ortho Pharmaceutical Corporation | 4-aryl- and 4-arylthio-5-hydroxy-2(5H)-furanones as inhibitors of phospholipase A2 |
| JPH07206841A (ja) | 1994-01-20 | 1995-08-08 | Sankyo Co Ltd | ブチロラクトンの製造法 |
| US6020343A (en) | 1995-10-13 | 2000-02-01 | Merck Frosst Canada, Inc. | (Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors |
| US5756518A (en) * | 1996-04-02 | 1998-05-26 | Kowa Co., Ltd. | Phenylene derivatives |
| WO1997037985A1 (en) * | 1996-04-10 | 1997-10-16 | Warner-Lambert Company | Nonpeptide endothelin antagonists with increased water solubility |
| US6005000A (en) * | 1996-08-22 | 1999-12-21 | Oxis International, Inc. | 5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor |
| US6008243A (en) * | 1996-10-24 | 1999-12-28 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use |
| BRPI0011172B8 (pt) * | 1999-04-14 | 2021-05-25 | Pacific Corp | derivados do 4,5-diaril-3(2h)-furanona como inibidores de ciclooxigenase-2 |
| US6576662B2 (en) * | 2000-05-05 | 2003-06-10 | Dr. Reddy's Laboratories Limited | Compounds having anticancer activity : process for their preparation and pharmaceutical compositions containing them |
-
2003
- 2003-01-28 US US10/354,474 patent/US6667330B2/en not_active Expired - Fee Related
- 2003-01-30 MX MXPA04007292A patent/MXPA04007292A/es unknown
- 2003-01-30 NZ NZ534305A patent/NZ534305A/en unknown
- 2003-01-30 JP JP2003564026A patent/JP2006502963A/ja active Pending
- 2003-01-30 AU AU2003207750A patent/AU2003207750A2/en not_active Abandoned
- 2003-01-30 WO PCT/US2003/002766 patent/WO2003064403A1/en not_active Ceased
- 2003-01-30 EP EP03705988A patent/EP1478634A4/en not_active Withdrawn
- 2003-01-30 CA CA002474871A patent/CA2474871A1/en not_active Abandoned
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