JP2006500398A - 良性及び悪性の腫瘍疾患を処置するためのジソラゾール及びその誘導体を含有している医薬 - Google Patents

良性及び悪性の腫瘍疾患を処置するためのジソラゾール及びその誘導体を含有している医薬 Download PDF

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JP2006500398A
JP2006500398A JP2004535140A JP2004535140A JP2006500398A JP 2006500398 A JP2006500398 A JP 2006500398A JP 2004535140 A JP2004535140 A JP 2004535140A JP 2004535140 A JP2004535140 A JP 2004535140A JP 2006500398 A JP2006500398 A JP 2006500398A
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alkyl
disorazole
cancer
medicament
general formula
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JP2006500398A5 (https=
Inventor
イルシク ヘルベルト
ヤンセン ロルフ
ザッセ フローレンツ
バースナー ジルケ
シュミット ペーター
ギュンター エックハルト
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Aeterna Zentaris GmbH
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Zentaris AG
Aeterna Zentaris GmbH
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    • C07ORGANIC CHEMISTRY
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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JP2004535140A 2002-08-24 2003-08-22 良性及び悪性の腫瘍疾患を処置するためのジソラゾール及びその誘導体を含有している医薬 Withdrawn JP2006500398A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40559402P 2002-08-24 2002-08-24
PCT/EP2003/009329 WO2004024149A1 (de) 2002-08-24 2003-08-22 Arzneimittel enthaltend disorale und ihre derivate und deren anwendung zur behandlung gutartiger und bosärtiger tumorerkrankungen

Publications (2)

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JP2006500398A true JP2006500398A (ja) 2006-01-05
JP2006500398A5 JP2006500398A5 (https=) 2006-10-05

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JP2004535140A Withdrawn JP2006500398A (ja) 2002-08-24 2003-08-22 良性及び悪性の腫瘍疾患を処置するためのジソラゾール及びその誘導体を含有している医薬

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US (2) US20040106662A1 (https=)
EP (1) EP1536789A1 (https=)
JP (1) JP2006500398A (https=)
KR (1) KR20050038632A (https=)
CN (1) CN1678310A (https=)
AR (1) AR042617A1 (https=)
AU (1) AU2003296872B2 (https=)
BR (1) BR0313789A (https=)
CA (1) CA2438001A1 (https=)
HR (1) HRP20050277A2 (https=)
IL (1) IL166588A0 (https=)
MX (1) MXPA05002157A (https=)
NO (1) NO20051444L (https=)
NZ (1) NZ538926A (https=)
PL (1) PL376407A1 (https=)
RU (1) RU2322236C2 (https=)
TW (1) TW200404537A (https=)
UA (1) UA79480C2 (https=)
WO (1) WO2004024149A1 (https=)
ZA (1) ZA200501196B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010502673A (ja) * 2006-09-06 2010-01-28 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング 細胞結合分子を有するジソラゾールのコンジュゲート及びそれらの誘導体、新規ジソラゾール誘導体、それらの製法ならびに使用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101578287B (zh) * 2006-09-06 2012-09-05 阿特纳赞塔里斯有限公司 地索拉唑及其衍生物与细胞结合分子的轭合物,新的地索拉唑衍生物,其制备方法及其应用
EP1900742A1 (en) * 2006-09-07 2008-03-19 AEterna Zentaris GmbH Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof
EP3641891A4 (en) 2017-06-22 2021-01-27 William Marsh Rice University SYNTHESIS OF DISORAZOLES AND THEIR ANALOGUES AS POWERFUL ANTI-CANCER AGENTS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19605024A1 (de) * 1996-01-31 1997-08-07 Schering Ag Neue selektive Taxane, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
PT1412332E (pt) * 2001-07-31 2005-06-30 Jerome P Horwitz Derivados de quinolina e sua utilizacao como agentes antitumorais
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
US7364877B2 (en) * 2002-12-06 2008-04-29 Kosan Biosciences, Inc. Polynucleotides encoding disorazole polyketide synthase polypeptides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010502673A (ja) * 2006-09-06 2010-01-28 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング 細胞結合分子を有するジソラゾールのコンジュゲート及びそれらの誘導体、新規ジソラゾール誘導体、それらの製法ならびに使用

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Publication number Publication date
HRP20050277A2 (en) 2005-04-30
BR0313789A (pt) 2005-07-05
IL166588A0 (en) 2006-01-15
UA79480C2 (en) 2007-06-25
CN1678310A (zh) 2005-10-05
US20090311264A1 (en) 2009-12-17
CA2438001A1 (en) 2004-02-24
MXPA05002157A (es) 2005-05-23
WO2004024149A1 (de) 2004-03-25
EP1536789A1 (de) 2005-06-08
US20040106662A1 (en) 2004-06-03
RU2005108570A (ru) 2005-08-27
AR042617A1 (es) 2005-06-29
NO20051444L (no) 2005-05-19
KR20050038632A (ko) 2005-04-27
PL376407A1 (en) 2005-12-27
AU2003296872B2 (en) 2008-02-14
RU2322236C2 (ru) 2008-04-20
NZ538926A (en) 2006-03-31
TW200404537A (en) 2004-04-01
AU2003296872A1 (en) 2004-04-30
ZA200501196B (en) 2005-10-26

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